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Mircera 50mcg Injection is used to treat anaemia due to chronic kidney disease. It contains Methoxy polyethylene glycol and Epoetin beta which work by stimulating the bone marrow to make more red blood cells. In some cases, this medicine may cause side effects such as pain, itching, swelling or redness at the injection site, vomiting, diarrhoea, headache, constipation, stomach pain, fever and chills. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Mircera 50mcg Injection

Mircera 50mcg Injection is a prescription injection used to treat anaemia, a medical condition where your body does not have enough healthy red blood cells. It is specifically used to treat anaemia associated with chronic kidney disease in both adults and children. By encouraging your body to produce more red blood cells, this medicine helps manage the severe fatigue caused by this condition.

Because this medication is long-acting, you will typically inject it less frequently than other similar treatments, usually once a month or once every two weeks. It is highly important to receive or inject your doses consistently on the exact schedule set by your healthcare team. This medicine can be injected with or without regard to food, but supporting your treatment with a proper diet and regular blood pressure monitoring will help you get the best results.

While using this medicine, you may experience some common, mild side effects such as mild headaches, back pain, or temporary discomfort where the injection was given. However, you must contact your doctor immediately if you experience any serious side effects, such as a sudden severe headache, chest pain, or signs of an allergic reaction like hives and difficulty breathing.

Before starting your treatment, talk to your doctor if you have a history of heart disease, seizures, or high blood pressure that is difficult to manage. Do not take this if you have severe, uncontrolled high blood pressure, or if you have ever had a condition called pure red cell aplasia after using similar red blood cell-stimulating medications.

You should avoid smoking during your treatment because it can further strain your heart and blood vessels, and you should check with your doctor before combining this injection with other prescription drugs that might alter your blood cell production. If you are pregnant, planning to breastfeed, or are an older adult, consult your doctor or pharmacist to ensure this treatment is safe for your specific situation.

Uses of Mircera 50mcg Injection

Mircera 50mcg Injection is used to treat anaemia (low haemoglobin in the blood). The detailed uses of Mircera 50mcg Injection are as follows:

  • Anaemia associated with chronic kidney disease: Mircera 50mcg Injection helps by stimulating your bone marrow to produce more red blood cells, which improves oxygen delivery throughout your body and relieves severe fatigue.
  • Anaemia in patients on dialysis: For individuals undergoing hemodialysis or peritoneal dialysis, Mircera 50mcg Injection helps maintain stable red blood cell levels, reducing the need for frequent blood transfusions.

Key Benefits

Mircera 50mcg Injection helps increase red blood cell production in people with anaemia associated with chronic kidney disease, improving oxygen delivery throughout the body. This helps relieve symptoms of anaemia, reduce the need for blood transfusions, and support better daily functioning and quality of life.

Benefits may include:

  • Helps reduce fatigue, weakness, and lack of energy caused by anaemia.
  • Increases red blood cell production to improve oxygen supply to the body's tissues.
  • Helps improve physical stamina and supports everyday activities.
  • Reduces the need for frequent red blood cell transfusions in many patients.
  • Helps lower the risks associated with repeated blood transfusions.
  • Supports better overall quality of life by helping maintain healthier haemoglobin levels when used as prescribed.
Side effects of Mircera 50mcg Injection 0.3 ml
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to manage the medication-triggered Common Cold:
  • Inform your doctor about the common cold symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Drink plenty of fluids, such as warm water or soup, to help thin out mucus.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Gently massage the affected area using your hands or a massager.
  • Light exercises such as walking or climbing stairs may help the muscles return to normal.
  • Apply heat/ice to the affected area.
  • Drink electrolyte-rich fluids.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Mircera 50mcg Injection may be administered by your doctor, or you may be told to inject the medication yourself at home. Your doctor will train you on how to use Mircera 50mcg Injection at home. Check the label for directions and use it as advised by the doctor. Mircera 50mcg Injection should be administered subcutaneously (under the skin) in the thighs, abdomen, buttocks, or upper arm.
  • Rotate the injection site each time. Do not inject into the areas where the skin is tender, red, bruised, hard, scarred or has stretch marks.

How Mircera 50mcg Injection Works

Mircera 50mcg Injection works by mimicking a natural hormone in your body called erythropoietin, which is produced by healthy kidneys. This hormone signals your bone marrow to produce red blood cells. In chronic kidney disease, the kidneys cannot make enough of this hormone, leading to anaemia. Mircera 50mcg Injection binds to the same receptors in your body but has a much longer-lasting effect than the natural hormone, allowing your body to steadily generate healthy red blood cells over a longer period.
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Alcohol

Caution

It is not known that Mircera 50mcg Injection may interact with alcohol. Therefore, avoid drinking alcohol while using Mircera 50mcg Injection .

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Pregnancy

Caution

Mircera 50mcg Injection should not be taken until prescribed. Your doctor will decide what the best treatment for you is. Please consult your doctor.

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Breast Feeding

Caution

Inform your doctor before taking Mircera 50mcg Injection . Your doctor will advise you to either stop or continue treatment.

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Driving

Safe if prescribed

Mircera 50mcg Injection usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Take Mircera 50mcg Injection with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Safe if prescribed

Mircera 50mcg Injection is safely given to kidney patients only if prescribed by your doctor.

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Children

Caution

Mircera 50mcg Injection is safe for children above 5 years of age.

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Heart

Consult your doctor

Let your doctor know if you have any pre-existing herat conditions.

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Geriatrics

Consult your doctor

Limited information available for use of Mircera 50mcg Injection in elderly patients. Please consult your doctor.

What if I have taken an overdose of Mircera 50mcg Injection

If you suspect you have received too much of this medication, seek immediate medical attention or contact a poison control centre, as it can cause a dangerous spike in blood pressure or red blood cell levels.

Diet & Lifestyle Advise

  • Iron-Rich Diet: Ensure you get enough iron, as your body needs iron to build red blood cells. Your doctor may prescribe iron supplements or advise you on safe dietary sources depending on your kidney health.
  • Monitor Blood Pressure: High blood pressure is a common concern with this medicine. Check your blood pressure regularly at home as instructed by your healthcare team.
  • Follow Renal Diet Guidelines: Stick closely to the diet plan provided by your kidney specialist, which may include managing your intake of fluids, potassium, phosphorus, and sodium.
  • Avoid Smoking: Smoking restricts blood vessels and puts extra strain on your cardiovascular system, which is particularly risky when taking this type of medication.
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How Soon It Starts Working

The time required for Mircera 50mcg Injection to start to work: The time required for Mircera 50mcg Injection to show its action is unknown. The time for which the effects of Mircera 50mcg Injection last: The duration of action for Mircera 50mcg Injection is clinically unknown.

What if you forget to take Mircera 50mcg Injection

If you miss a dose of Mircera 50mcg Injection , do not take a double dose to make up for it. Contact your doctor or pharmacist right away to find out when you should receive your next injection.

Storage

• Store Mircera 50mcg Injection in the refrigerator between 2°C and 8°C.
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Keep Refrigerated. Do not freeze.Prepaid payment required.

Drug Warnings

  • Avoid using: Do not use this medicine if you have uncontrolled high blood pressure or have previously developed Pure Red Cell Aplasia (PRCA) after treatment with another erythropoiesis-stimulating agent.
  • Check the Expiry Date: Always check the expiration date on the package before injecting.
  • Inspect the Solution Before Use: Inspect the liquid inside the prefilled syringe; if it is cloudy, discoloured, or contains floating particles, do not use it and contact your pharmacist.
  • Do Not Shake the Syringe: Never shake the syringe. Shaking can damage the delicate medicine and make it ineffective.
  • Rotate Injection Sites: Rotate your injection sites (e.g., alternating between thighs and abdomen) to avoid hard lumps or skin breakdown.
  • Never Reuse Needles or Syringes: Never reuse a syringe or needle. Always use a brand-new, sterile syringe for every dose.
  • Monitor Your Blood Pressure: Ensure your blood pressure is well-controlled before starting this medicine, and monitor it closely throughout your treatment.
  • Keep Up with Blood Tests: Regular monitoring of your haemoglobin levels, blood pressure, and iron stores helps your doctor adjust your dose safely and reduce the risk of complications.

Drug-Drug Interactions

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  • Iron Supplements: Iron levels may need monitoring or supplementation because the medicine increases iron use during red blood cell production.
  • Other Erythropoietin-stimulating agents (ESAs): Do not use together, as this may cause excessively high haemoglobin levels and increase the risk of serious cardiovascular complications.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No clinically significant food interactions are known with Mircera 50mcg Injection when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[MISCELLANEOUS]

FAQs

Mircera 50mcg Injection is used to treat anaemia (lack of haemoglobin in blood) due to chronic kidney disease.
Mircera 50mcg Injection works by stimulating the bone marrow (soft tissue within the bones that makes red blood cells) to make more red blood cells. This Mircera 50mcg Injection is very similar to the natural substance in the body known as erythropoietin (hormone formed by kidneys and produced RBC) which prevents anaemia (lack of haemoglobin and RBC in the blood).
You need to tell your doctor about all the prescription and nonprescription medications, vitamins, and nutritional supplements you plan to take. Your doctor may need to change the doses of your medications or monitor you carefully for side effects and if there is any high blood pressure, heart disease (such as heart failure, past heart attack/stroke), seizure disorder, or severe anaemia caused by antibodies to past erythropoietin-type treatment (pure red cell aplasia).
The most common side effects of Mircera 50mcg Injection are high blood pressure, vomiting, diarrhoea, headache, constipation, stomach pain, back pain, pain in the legs or hands, fever and chills. Most of these side effects of Mircera 50mcg Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
You may observe symptoms like racing or a fast heartbeat on the overdose of Mircera 50mcg Injection . Immediately inform your doctor or nurse if you think too much Mircera 50mcg Injection has been injected.
Mircera 50mcg Injection can increase your blood pressure, particularly during the early stages of treatment when your red blood cell levels are rising. Your doctor will check your blood pressure regularly to detect and manage any increases promptly, and may prescribe or adjust blood pressure medicines if needed. In some cases, treatment with Mircera 50mcg Injection may be stopped if blood pressure remains uncontrolled. Tell your doctor if you notice your blood pressure is higher than usual or if you develop symptoms such as severe headache, dizziness, or blurred vision.
Yes, you or a caregiver can learn to inject Mircera 50mcg Injection at home. Your healthcare provider will give you detailed training on how to prepare and inject the medicine safely. Do not attempt to inject it until you feel fully comfortable doing so. Talk to your doctor if you have any doubts.
If Mircera 50mcg Injection has been left out of the refrigerator, do not use it if it has been exposed to high heat or direct sunlight. If it was left at room temperature for a short period, contact your pharmacist to find out if it is still safe to use. Talk to your doctor or pharmacist before using any medicine that was stored incorrectly.
The safety of this medication during pregnancy and breastfeeding is not fully established. If you are pregnant, planning to become pregnant, or breastfeeding, you must discuss the risks and benefits of this treatment with your healthcare team. Talk to your doctor to find the safest option for you.
Many patients need to take iron supplements because this medicine uses up their body's iron stores to create new red blood cells. Your doctor will test your iron levels and prescribe a supplement if necessary. Talk to your doctor before starting any over-the-counter iron supplements.
This medication is a long-acting form of erythropoietin, meaning it stays active in your body for a longer period. This typically allows for less frequent dosing (such as once a month) compared to older treatments that require multiple injections per week. Talk to your doctor to see if this is the right option for you.
While rare, medicines that stimulate red blood cell production can increase the risk of blood clots. Seek immediate medical attention if you experience sudden pain, warmth, redness, or swelling in one of your legs, chest pain, or sudden shortness of breath. Talk to your doctor if you have a history of blood clots before starting treatment.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

INDIA

Manufacturer/Marketer address

1503, 15th Floor, ‘The Capital’, Plot no. C-70, Behind ICICI Bank, BKC, Bandra (E) , Mumbai 400051
Other Info - MIR0014
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