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compositionComposition:LOMUSTINE-40MG
prescription
Prescription Medicine
info
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MOOSTIN 40MG TABLET is used to treat Brain Tumors and Hodgkin's Disease. It contains Lomustine, which belongs to the alkylating agent’s class. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis. This causes shrinkage of tumor cells and thereby prevents the growth and further spread of cancerous or non-cancerous cells. Common side effects of this medication may include nausea, vomiting, headache, visual disturbances, blindness, disorientation, lack of energy, loss of control, and difficulty talking.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

LOMUSTINE-40MG

Manufacturer/Marketer :

Miracalus Pharma Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About MOOSTIN 40MG TABLET

MOOSTIN 40MG TABLET is a prescription medication used to treat certain types of brain tumours and Hodgkin's lymphoma. It is primarily prescribed when other therapies have not worked or as part of a combined chemotherapy plan to help stop cancer cells from growing.

Unlike daily medications, you typically take MOOSTIN 40MG TABLET as a single oral dose once every 6 weeks. It is best to take this medication on an empty stomach or at bedtime to help prevent nausea and vomiting. Making simple adjustments, such as getting plenty of rest and staying well-hydrated, can help support your body during this treatment cycle.

Common side effects include temporary hair loss, nausea, and a decreased appetite. Because this medication can lower your body's ability to fight infections, you must consult your doctor immediately if you experience serious symptoms like a high fever, severe chills, or unusual bleeding.

Talk to your doctor before starting MOOSTIN 40MG TABLET if you have a history of liver damage, kidney disease, or lung problems. Do not take this if you are pregnant, planning to become pregnant, or currently have severely weakened bone marrow.

This medication can interact with other drugs, alcohol, and vaccines, which can increase your risk of severe complications. Specific groups, including pregnant women, breastfeeding mothers, and older adults, must consult their doctor to discuss the risks and benefits before taking MOOSTIN 40MG TABLET.

Uses of MOOSTIN 40MG TABLET

MOOSTIN 40MG TABLET is used to treat certain types of brain tumours and Hodgkin's lymphoma. The detailed uses of MOOSTIN 40MG TABLET are as follows:

  • Brain tumours: MOOSTIN 40MG TABLET helps by slowing down or stopping the growth of cancer cells in the brain, making it a valuable treatment option for specific brain cancers.
  • Hodgkin's lymphoma: This medicine is used to target and destroy cancer cells in the lymphatic system when standard treatments have not been successful.

Key Benefits

MOOSTIN 40MG TABLET helps treat certain types of cancer by slowing the growth and spread of cancer cells. With regular use as prescribed, it helps control tumour progression, relieve cancer-related symptoms, and support effective long-term treatment.

  • Targets Cancer Cells Effectively: By interfering with the growth and division of rapidly multiplying cancer cells, this medicine helps slow tumour growth and limit the spread of cancer.
  • Treats Tumours in the Brain: Because this medicine can cross the blood-brain barrier, it is able to reach and treat certain brain tumours and cancers that have spread to the brain, where many chemotherapy medicines have limited access.
  • Supports Symptom Relief and Disease Control: By helping shrink tumours and reduce their growth, this medicine may relieve tumour-related symptoms, improve daily comfort, and support better overall treatment outcomes.
Side effects of Moostin 40mg Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.
  • Eat well-cooked food to minimize infection risk.
  • Practice good hand hygiene to prevent infections.
  • Avoid crowds and people with illnesses to reduce exposure.
  • Wear a mask when necessary to lower infection risk.
  • Rest adequately to support your body's healing process.
  • Stay hydrated by drinking plenty of water.
  • Regularly monitor blood cell counts for changes.
  • Seek immediate medical help if symptoms like fever, chills, or fatigue occur.
  • Consult your doctor right away if concerning symptoms arise.
  • Follow your doctor's guidance on managing myelosuppression and infection prevention.

Directions for Use

  • MOOSTIN 40MG TABLET can be taken 1 hour before a meal or 2 hours after a meal, or as advised by your doctor.
  • It is taken as a single dose every 6 weeks; however, follow your doctor’s advice regarding the dosage and duration.
  • Swallow the medicine as a whole with a glass of water.
  • Do not break, chew or crush MOOSTIN 40MG TABLET.

How MOOSTIN 40MG TABLET Works

MOOSTIN 40MG TABLET contains lomustine, which belongs to a class of medications called alkylating agents. It works by entering rapidly dividing cancer cells and attaching itself to their DNA. This attachment damages the genetic structure of the cells, preventing them from reproducing or repairing themselves. Since cancer cells divide much faster than normal, healthy cells, they are highly vulnerable to this genetic damage. Once their DNA is disrupted, the cancer cells cannot multiply and eventually die, which helps slow down or stop the progression of the disease.
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Alcohol

Unsafe

Avoid alcohol consumption while on treatment with MOOSTIN 40MG TABLET to prevent serious adverse effects.

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Pregnancy

Unsafe

MOOSTIN 40MG TABLET is not recommended for use in pregnancy as it may harm your fetus. If you are pregnant or planning pregnancy, inform your doctor before taking MOOSTIN 40MG TABLET.

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Breast Feeding

Unsafe

Avoid breastfeeding your child while on treatment with MOOSTIN 40MG TABLET as it causes serious side effects to the baby.

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Driving

Unsafe

MOOSTIN 40MG TABLET may cause visual disturbances as a side effect. Avoid driving vehicles or operating machines until you are alert.

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Liver

Caution

MOOSTIN 40MG TABLET may cause hepatotoxicity. If you have a pre-existing or a history of liver disease, inform your doctor before taking MOOSTIN 40MG TABLET. Your liver function should be monitored carefully before, during and after the treatment with MOOSTIN 40MG TABLET.

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Kidney

Caution

MOOSTIN 40MG TABLET and its metabolites are known to be largely eliminated via the kidney, and the risk of adverse responses to this medicine may be higher in patients with impaired renal function. It may cause nephrotoxicity with progressive renal failure and a decrease in kidney size. Hence, if you have a pre-existing or a history of kidney disease, inform your doctor before taking MOOSTIN 40MG TABLET.

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Children

Caution

Please consult a doctor. Your child's doctor may recommend this medicine based on the age, body weight and disease condition of your child.

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Heart

Consult your doctor

Please consult your doctor before receiving MOOSTIN 40MG TABLET if you have pre-existing heart problems. Your doctor will prescribe MOOSTIN 40MG TABLET if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Limited information available about the use of MOOSTIN 40MG TABLET in geriatric patients. Please consult your physician.

What if I have taken an overdose of MOOSTIN 40MG TABLET

If you or someone else accidentally takes more than the prescribed dose of MOOSTIN 40MG TABLET, seek emergency medical care immediately. An overdose can cause severe damage to your blood cells, liver, and digestive tract.

Diet & Lifestyle Advise

  • Avoid crowds and sick contacts: Your white blood cell counts will drop significantly a few weeks after your dose, making you highly vulnerable to infections. Stay away from crowded public spaces and anyone with a cold or flu.
  • Prevent bleeding and bruising: Use a soft-bristled toothbrush and an electric razor to prevent cuts. Avoid contact sports, heavy lifting, or activities that could lead to falls or injuries.
  • Manage nausea proactively: Eat small, frequent meals rather than large ones. If your doctor prescribes anti-nausea medication, take it exactly as directed before your MOOSTIN 40MG TABLET dose.
  • Stay well-hydrated: Drink plenty of water, clear broths, or herbal teas in the days following your dose to help support your kidneys and prevent dehydration.
health query

Have a query?

How Soon It Starts Working

The time required for MOOSTIN 40MG TABLET to start to work: MOOSTIN 40MG TABLET ideally shows its action within 3 hours after administration. The time for which the effects of MOOSTIN 40MG TABLET last: The duration of action for MOOSTIN 40MG TABLET is unknown.

What if you forget to take MOOSTIN 40MG TABLET

Because MOOSTIN 40MG TABLET is taken only once every 6 weeks, missing a dose can disrupt your treatment plan. If you miss your scheduled dose, contact your doctor or oncology clinic immediately for guidance. Do not take a double dose to make up for a missed one.

Storage

•Store MOOSTIN 40MG TABLET capsules at room temperature, strictly below 25°C (77°F). •Keep the bottle tightly closed in its original packaging to protect the medicine from moisture and light.

Drug Warnings

  • Monitor for delayed blood count drops: Keep in mind that MOOSTIN 40MG TABLET causes your blood cell counts to drop 4 to 6 weeks after you take your dose, not right away. Attend all scheduled blood test appointments so your doctor can monitor this safely.
  • Handle capsules with extreme care: Always wear disposable gloves when touching the capsules. If a capsule is broken or leaking, do not touch it with bare hands; clean it up using a damp paper towel while wearing gloves and place it in a sealed plastic bag.
  • Use highly effective birth control: Both men and women must use dependable birth control during treatment and for several months after the final dose, as this medicine can cause severe birth defects.
  • Avoid live vaccines: Do not receive live vaccines (such as the MMR or shingles vaccine) while taking MOOSTIN 40MG TABLET, as your weakened immune system could allow the virus to cause a severe infection.

Drug-Drug Interactions

verifiedApollotooltip
  • Other chemotherapy drugs: Taking MOOSTIN 40MG TABLET with other cancer treatments can severely increase the risk of low blood cell counts, raising your risk of infection and bleeding.
  • Live vaccines: Combined use can lead to serious, life-threatening infections because your immune system is less able to fight off live viruses.
  • Blood thinners: Medications that prevent blood clots can greatly increase your risk of severe bleeding when taken alongside MOOSTIN 40MG TABLET.
LomustineEtanercept
Severe
LomustineInfliximab
Severe

Drug-Drug Interactions

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LomustineEtanercept
Severe
How does the drug interact with Moostin 40mg Tablet:
When Etanercept is used with Moostin 40mg Tablet, the likelihood or severity of infection may increase.

How to manage the interaction:
There may be a possibility of interaction between Etanercept and Moostin 40mg Tablet, but it can be taken if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
LomustineInfliximab
Severe
How does the drug interact with Moostin 40mg Tablet:
Combining Infliximab with Moostin 40mg Tablet can increase the risk or severity of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between Infliximab and Moostin 40mg Tablet, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, losing weight, or experiencing pain or burning while urinating, contact a doctor right away. Do not discontinue any medications without consulting a doctor.
LomustineBaricitinib
Severe
How does the drug interact with Moostin 40mg Tablet:
Using baricitinib together with Moostin 40mg Tablet may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction between Baricitinib and Moostin 40mg Tablet, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms - fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain or burning during urination - consult a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Drinking alcohol while on this medication can increase stomach irritation, worsen nausea, and place extra strain on your liver.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[CHEMOTHERAPY]

FAQs

MOOSTIN 40MG TABLET is used to treat Brain Tumors and Hodgkin's Disease.
MOOSTIN 40MG TABLET contains Lomustine, which belongs to the alkylating agents class. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis.
MOOSTIN 40MG TABLET is effective in treating brain tumours and Hodgkin's lymphoma (a rare type of blood cancer that affects the lymphatic system). However, its effectiveness can vary depending on the type and stage of cancer, how the body responds to the medication, and whether it is used alone or in combination with other anti-cancer drugs. Always follow your doctor's instructions, as proper dosing and monitoring are crucial for maximizing its effectiveness.
MOOSTIN 40MG TABLET has a long half-life, typically 16 to 48 hours, meaning it can remain in your body for several days. However, its effects can last longer, as it works in the body for weeks.
If you miss a dose of MOOSTIN 40MG TABLET, take it as soon as you remember unless it is almost time for your next dose. In that case, skip the missed dose and take your next dose at the usual time. Do not take two doses at once to make up for a missed dose. Always follow your doctor's instructions for dosing.
MOOSTIN 40MG TABLET may cause common side effects, such as nausea, vomiting, headache, visual disturbances, blindness, disorientation, lack of energy, loss of control, and difficulty talking in some individuals. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Before taking MOOSTIN 40MG TABLET, it's important to share your medical history and current medications with your doctor. If you have any allergies, liver or kidney problems, or breathing issues, be sure to let them know. MOOSTIN 40MG TABLET can lower your blood count, making you more prone to infections or bleeding, and may cause vision problems, so be careful when driving or operating machinery. Additionally, if you're pregnant or breastfeeding, inform your doctor, and children should only take MOOSTIN 40MG TABLET under a paediatrician's care. Typically taken every 6 weeks, be sure to consult your doctor or pharmacist before starting treatment.
Yes, women can use MOOSTIN 40MG TABLET only if recommended by a doctor. MOOSTIN 40MG TABLET is a chemotherapy drug, and its use may require special considerations for women, particularly those who are pregnant, breastfeeding, or planning to become pregnant. This is because it can harm the developing foetus or be passed to the baby through breast milk. Always consult with your doctor before using MOOSTIN 40MG TABLET. Your doctor will evaluate the benefits and risks before prescribing it and may monitor you for any side effects.
MOOSTIN 40MG TABLET has a delayed effect on your body, particularly on your bone marrow's ability to produce new blood cells. It takes several weeks for your blood counts to drop and then safely recover, making a 6-week break necessary between doses. Talk to your doctor if you have questions about your specific treatment schedule.
No, you must swallow the capsules whole. Opening, crushing, or chewing the capsules is highly dangerous because the active powder can damage your skin, mouth, or lungs if touched or inhaled. Talk to your doctor if you have trouble swallowing capsules.
If you vomit after taking your dose, do not take an extra capsule to replace it. Contact your doctor or oncology team immediately to receive safe instructions on how to proceed. Talk to your doctor about using anti-nausea medications before your next scheduled dose.
It is highly recommended to avoid alcohol while taking this medicine. Alcohol can worsen stomach irritation, increase nausea and vomiting, and add extra stress to your liver during treatment. Talk to your doctor for personalised advice.
You can generally receive an inactive (dead) flu shot, but you must avoid the live nasal spray flu vaccine. Because MOOSTIN 40MG TABLET weakens your immune system, live vaccines can cause serious infections. Talk to your doctor before receiving any vaccine.
Your doctor must monitor your blood counts closely because MOOSTIN 40MG TABLET causes a delayed drop in white blood cells, red blood cells, and platelets about 4 to 6 weeks after your dose. These tests ensure your body is recovering safely. Talk to your doctor about your blood test schedule.
No, you should not breastfeed while taking MOOSTIN 40MG TABLET and for a period after your final dose, as this medication can pass into breast milk and cause severe harm to your baby. Talk to your doctor to discuss safe feeding options for your child.

Disclaimer

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Country of origin

India

Manufacturer/Marketer address

213, Shivai Dongre Industrial Premises, Andheri - Kurla Road, Andheri(E), Mumbai - 400 072, Maharashtra, India.
Other Info - MOO0029
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