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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Mounjaro 2.5mg Solution for Injection 0.5 ml is an antidiabetic medicine used to treat Type II Diabetes as an adjunct to diet and exercise. It contains Tirzepatide, which works by activating both GIP (glucose-dependent insulin polypeptide) and GLP-1 (glucagon-like peptide-1) hormone receptors, thereby helping control blood sugar levels. In obese people, it slows gastric emptying and fosters a sense of fullness, leading to better weight loss. This medicine may cause specific side effects such as vomiting, nausea, abdominal pain, diarrhoea, headache and allergic reactions. Mounjaro 2.5mg Solution for Injection 0.5 ml should be stored in cold places at 2°C to 8°C.

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Composition :

TIRZEPATIDE-2.5MG

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Mounjaro 2.5mg Solution for Injection 0.5 ml

Mounjaro 2.5mg Solution for Injection 0.5 ml is an antidiabetic medicine used to treat diabetes. It is used for the treatment of Type II Diabetes. Type II Diabetes Mellitus is a serious condition wherein the body doesn’t use insulin effectively, which causes unusual blood glucose levels. Mounjaro 2.5mg Solution for Injection 0.5 ml is also used in combination with other medicines to treat obesity.

Mounjaro 2.5mg Solution for Injection 0.5 ml contains Tirzepatide, which belongs to the class of GLP-1 receptor agonist. This medicine works by activating both GIP (glucose-dependent insulin polypeptide) and GLP-1 (glucagon-like peptide-1) hormone receptors, thereby helping control blood sugar levels. It also helps reduce appetite by delaying the stomach's emptying process and interacting with brain areas that contain GLP-1 receptors, which signal feelings of fullness.

Mounjaro 2.5mg Solution for Injection 0.5 ml should be administered as recommended by your doctor. Your doctor will clearly explain how to adjust the dose and administer the medicine. This medicine may cause specific side effects such as vomiting, nausea, abdominal pain, diarrhea, headache, and allergic reactions. If these side effects persist or worsen, please consult your doctor.

Mounjaro 2.5mg Solution for Injection 0.5 ml should be avoided if you are allergic to any of the medicines or their components. Inform your doctor about your medical history and other conditions like liver/kidney disease, stomach problems, vision problems (retinopathy), pancreatitis, depression, and hypoglycemia. This can help prevent unwanted effects. Let your doctor know if you are pregnant or breastfeeding before taking Mounjaro 2.5mg Solution for Injection 0.5 ml. This medicine should be stored in cold places at 2°C to 8°C.

Uses of Mounjaro 2.5mg Solution for Injection 0.5 ml

Treatment of Type II Diabetes Mellitus: Mounjaro 2.5mg Solution for Injection 0.5 ml is used in the treatment of type II Diabetes Mellitus. It is a viable alternative for supplementing the incretin effect in achieving glycemic control, as this impact is weakened in diabetes, with the additional benefits of glycosylated hemoglobin (HbA1c) reduction.Management of weight loss: Mounjaro 2.5mg Solution for Injection 0.5 ml is used to manage weight loss in obese people. It helps prolong the sensation of fullness and thereby promotes weight loss, cardiovascular health, a good lipoprotein profile, and improvement in nonalcoholic steatohepatitis.

Directions for Use

This injection comes as a multi-dose vial. It should be given subcutaneously in the abdomen, thigh, or upper arm. Mounjaro 2.5mg Solution for Injection 0.5 ml should be administered once a week with or without food. Your doctor will explain how to use the medicine. Mounjaro 2.5mg Solution for Injection 0.5 ml would not be administered intramuscularly or intravenously.

Medicinal Benefits

Mounjaro 2.5mg Solution for Injection 0.5 ml contains Tirzepatide. The medication maximizes the effects of GLP-1 drugs like semaglutide by helping people with type 2 diabetes lose weight and achieve far better glycemic control. It enhances the body's response to insulin, promoting better glucose control and reducing fat storage.

How Mounjaro 2.5mg Solution for Injection 0.5 ml Works

Mounjaro 2.5mg Solution for Injection 0.5 ml contains Tirzepatide, which belongs to the class of GLP-1 receptor agonist. This medicine works by activating both GIP (glucose-dependent insulin polypeptide) and GLP-1 (glucagon-like peptide-1) hormone receptors, thereby helping control blood sugar levels. In obese people, it slows gastric emptying and fosters a sense of fullness, leading to better weight loss. It also decreases hunger by delaying the stomach's emptying period and interacting with brain regions that contain GLP-1 receptors, indicating fullness.
Side effects of Mounjaro 2.5mg Solution for Injection 0.5 ml
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Consume more protein-rich foods and healthy fats like beans, avocados, cheese, nuts and lean meats to minimize appetite.
  • Prefer foods high in fiber to help feel full for a long time.
  • If you have decreased appetite, eat only when you are hungry.
  • Eat several small meals or snacks all day.
  • Try to take only small sips of fluids while eating.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • If you experience symptoms of increased levels of amylase like nausea, vomiting, pain in the upper abdomen that may spread to the back, bloating, loss of appetite or fast heartbeat while taking a medicine, consult your doctor and discuss about discontinuing the suspected medicine or switching to alternative medicine.
  • Your doctor may recommend regular blood tests to monitor your amylase levels and check if the medicine is still causing a problem.

What if I have taken an overdose of Mounjaro 2.5mg Solution for Injection 0.5 ml

Please do not exceed the recommended dose. An overdose of Mounjaro 2.5mg Solution for Injection 0.5 ml may cause low blood sugar, stomach pains, feeling or being sick (nausea or vomiting), and feeling dizzy and worried. Seek immediate medical attention if you observe these symptoms or suspect that you might have taken an overdose.

Drug Warnings

Mounjaro 2.5mg Solution for Injection 0.5 ml should be avoided if you are allergic to any of the medicines or the components in it. Before starting the treatment, inform your doctor about your medical history and the medications you take, including herbs and supplements. This can help prevent unwanted effects. Mounjaro 2.5mg Solution for Injection 0.5 ml is not recommended for use in patients with severe liver/kidney disease, type I diabetes, family history of MTC (medullary thyroid carcinoma) or in patients with multiple endocrine neoplasia syndrome type 2. It is unknown whether Mounjaro 2.5mg Solution for Injection 0.5 ml can be given to pregnant women or breastfeeding mothers. Hence, inform your doctor if you are pregnant or breastfeeding. It is not recommended for use in children below 18 years of age. Caution should be exercised in conditions like liver/kidney disease, stomach problems, vision problems, pancreatitis, depression, gall bladder problems, malnutrition, and hypoglycemia.

Drug-Drug Interactions

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TirzepatideGatifloxacin
Critical
TirzepatideThiopental
Severe

Drug-Drug Interactions

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TirzepatideGatifloxacin
Critical
How does the drug interact with Mounjaro 2.5mg Solution for Injection 0.5 ml:
Gatifloxacin may reduce the effectiveness Mounjaro 2.5mg Solution for Injection 0.5 ml and therby increase the blood glucose levels.

How to manage the interaction:
Close blood glucose monitoring is recommended when on treatment with gatifloxacin along with Mounjaro 2.5mg Solution for Injection 0.5 ml.
TirzepatideThiopental
Severe
How does the drug interact with Mounjaro 2.5mg Solution for Injection 0.5 ml:
Mounjaro 2.5mg Solution for Injection 0.5 ml is one medication that can cause your stomach to empty more slowly. Even if you follow your doctor's orders to fast, you can still have stomach contents if you have a surgery or treatment that calls for general anesthesia with thiopental. This may make indigestion more likely while under anesthesia.

How to manage the interaction:
The doctor may advise you to temporarily stop taking Mounjaro 2.5mg Solution for Injection 0.5 ml beforehand, or they may take extra precautions during anesthesia and your operation or procedure to reduce the dangers, depending on your condition and unique situation. If you have any queries or worries, speak with your physician. Your physician might be able to recommend substitutes that don't compromise the security of your anesthetic.
TirzepatideKetamine
Severe
How does the drug interact with Mounjaro 2.5mg Solution for Injection 0.5 ml:
Mounjaro 2.5mg Solution for Injection 0.5 ml may cause the stomach to take longer to empty, which raises the possibility of vomiting during anesthesia and the inhalation of stomach contents into the lungs.

How to manage the interaction:
Before undergoing surgery or a procedure, inform doctor if on Mounjaro 2.5mg Solution for Injection 0.5 ml treatment. Doctor may temporarily stop the treatment or take further precautions to reduce the risks.
TirzepatidePropofol
Severe
How does the drug interact with Mounjaro 2.5mg Solution for Injection 0.5 ml:
This raises the possibility of regurgitation while under anesthesia, leading to the inhalation of stomach contents into the lungs, which can result in lung inflammation or damage.

How to manage the interaction:
Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interfere with the safety of your anesthesia. It is essential to inform your doctor about all other medications you are taking, including vitamins and herbal supplements. Do not stop using any medications without first talking to your doctor.
TirzepatideMethoxyflurane
Severe
How does the drug interact with Mounjaro 2.5mg Solution for Injection 0.5 ml:
Mounjaro 2.5mg Solution for Injection 0.5 ml may cause the stomach to take longer to empty, which raises the possibility of vomiting during anesthesia and the inhalation of stomach contents into the lungs.

How to manage the interaction:
Before undergoing surgery or a procedure, inform doctor if on Mounjaro 2.5mg Solution for Injection 0.5 ml treatment. Doctor may temporarily stop the treatment or take further precautions to reduce the risks.
TirzepatideSevoflurane
Severe
How does the drug interact with Mounjaro 2.5mg Solution for Injection 0.5 ml:
This raises the possibility of regurgitation while under anesthesia, leading to the inhalation of stomach contents into the lungs, which can result in lung inflammation or damage.

How to manage the interaction:
Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interfere with the safety of your anesthesia. It is essential to inform your doctor about all other medications you are taking, including vitamins and herbal supplements. Do not stop using any medications without first talking to your doctor.
TirzepatideIsoflurane
Severe
How does the drug interact with Mounjaro 2.5mg Solution for Injection 0.5 ml:
Mounjaro 2.5mg Solution for Injection 0.5 ml may cause the stomach to take longer to empty, which raises the possibility of vomiting during anesthesia and the inhalation of stomach contents into the lungs.

How to manage the interaction:
Before undergoing surgery or a procedure, inform doctor if on Mounjaro 2.5mg Solution for Injection 0.5 ml treatment. Doctor may temporarily stop the treatment or take further precautions to reduce the risks.
TirzepatideBexarotene
Severe
How does the drug interact with Mounjaro 2.5mg Solution for Injection 0.5 ml:
Taking bexarotene along with Mounjaro 2.5mg Solution for Injection 0.5 ml may increase the risk of inflammation of the pancreas resulting in increased triglyceride levels.

How to manage the interaction:
Close monitoring of tri glyceride levels is should be done when Mounjaro 2.5mg Solution for Injection 0.5 ml is co-administered along with bexarotene.
TirzepatideEnflurane
Severe
How does the drug interact with Mounjaro 2.5mg Solution for Injection 0.5 ml:
Mounjaro 2.5mg Solution for Injection 0.5 ml may cause the stomach to take longer to empty, which raises the possibility of vomiting during anesthesia and the inhalation of stomach contents into the lungs.

How to manage the interaction:
Before undergoing surgery or a procedure, inform doctor if on Mounjaro 2.5mg Solution for Injection 0.5 ml treatment. Doctor may temporarily stop the treatment or take further precautions to reduce the risks.
TirzepatideHalothane
Severe
How does the drug interact with Mounjaro 2.5mg Solution for Injection 0.5 ml:
Mounjaro 2.5mg Solution for Injection 0.5 ml may cause the stomach to take longer to empty, which raises the possibility of vomiting during anesthesia and the inhalation of stomach contents into the lungs.

How to manage the interaction:
Before undergoing surgery or a procedure, inform doctor if on Mounjaro 2.5mg Solution for Injection 0.5 ml treatment. Doctor may temporarily stop the treatment or take further precautions to reduce the risks.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Try doing 30 minutes of moderate-intensity physical activity or one hour and 15 minutes of high-intensity exercise weekly.
  • Include whole-grain foods, fruits, veggies and other fiber-enriched foods in your diet.
  • Add omega-3 fatty acid-containing oils for daily cooking.
  • Avoid too much stress, as it may elevate your blood sugar level. To control stress-related blood sugar changes, you can adopt stress management techniques like mindfulness, meditation, or yoga.
  • Loss of weight gradually to achieve a healthy body mass index (18.5 to 24.9).
  • Keep your blood pressure as normal (140/90) as possible, as it reduces the risk of cardiovascular diseases in diabetes patients.
  • Avoid smoking and alcohol consumption while on treatment with Mounjaro 2.5mg Solution for Injection 0.5 ml.
  • Take short, frequent meals, and avoid prolonged fasting when taking Mounjaro 2.5mg Solution for Injection 0.5 ml.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS
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Alcohol

Unsafe

Avoid drinking alcohol as it can cause serious adverse effects.

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Pregnancy

Consult your doctor

It is unknown whether Mounjaro 2.5mg Solution for Injection 0.5 ml can be taken for pregnant women or not. If you are pregnant or planning pregnancy, inform your doctor before receiving Mounjaro 2.5mg Solution for Injection 0.5 ml.

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Breast Feeding

Consult your doctor

It is unknown whether Mounjaro 2.5mg Solution for Injection 0.5 ml passes into breast milk. Hence, if breastfeeding, inform your doctor before receiving Mounjaro 2.5mg Solution for Injection 0.5 ml. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Safe if prescribed

Mounjaro 2.5mg Solution for Injection 0.5 ml usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Use Mounjaro 2.5mg Solution for Injection 0.5 ml with caution, especially if you have a history of liver disease. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

Use Mounjaro 2.5mg Solution for Injection 0.5 ml with caution, especially if you have a history of kidney disease. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Mounjaro 2.5mg Solution for Injection 0.5 ml is not recommended for children as the safety and effectiveness were not established.

Have a query?

FAQs

Mounjaro 2.5mg Solution for Injection 0.5 ml is used in the treatment of type II Diabetes Mellitus. It is a viable alternative for supplementing the incretin effect in achieving glycemic control, as this impact is weakened in diabetes, with the additional benefits of glycosylated hemoglobin (HbA1c) reduction. It also used to manage weight loss in obese people. It helps prolong the sensation of fullness and thereby promotes weight loss, cardiovascular health, a good lipoprotein profile, and improvement in nonalcoholic steatohepatitis.

Mounjaro 2.5mg Solution for Injection 0.5 ml contains Tirzepatide, which belongs to the class of GLP-1 receptor agonist. This medicine works by activating both GIP (glucose-dependent insulin polypeptide) and GLP-1 (glucagon-like peptide-1) hormone receptors, thereby helping control blood sugar levels. In obese people, it slows gastric emptying and fosters a sense of fullness, leading to better weight loss. It also decreases hunger by delaying the stomach's emptying period and interacting with brain regions that contain GLP-1 receptors, indicating fullness.

If a dose of Mounjaro 2.5mg Solution for Injection 0.5 ml is missed, give it as soon as possible within four days (96 hours); if more than four days have passed, skip the missed dose and return to your usual routine. If necessary, you can switch the day of weekly administration as long as there is a minimum of three days (72 hours) between the two doses.

Mounjaro 2.5mg Solution for Injection 0.5 ml should be kept between 2°C and 8°C in the refrigerator. Avoid freezing or using it once frozen. Keep the medicine in its original container to keep it from light. Mounjaro 2.5mg Solution for Injection 0.5 ml shouldn't be returned to the fridge if it has been kept at room temperature. If not utilized within 21 days of being removed from the refrigerator, discard.

Mounjaro 2.5mg Solution for Injection 0.5 ml is not recommended to treat type 1 diabetes (your body produces no insulin). It is used in the treatment of only Type II diabetes (a chronic and lifelong condition wherein the body doesn’t use insulin effectively, which causes unusual blood glucose levels).

Mounjaro 2.5mg Solution for Injection 0.5 ml can be taken with other diabetes medications if prescribed by the doctor. However, taking Mounjaro 2.5mg Solution for Injection 0.5 ml with other diabetes medications may increase the risk of hypoglycaemia (low blood sugar). Therefore inform your doctor about your complete medication history before starting treatment with Mounjaro 2.5mg Solution for Injection 0.5 ml.

Mounjaro 2.5mg Solution for Injection 0.5 ml may cause serious adverse effects like thyroid C-cell tumours, pancreatitis, diabetic retinopathy complications, acute kidney injury, hypersensitivity, and acute gallbladder disease. Consult the doctor if you notice any unusual symptoms.

You should inform the doctor if you get eye problems, such as changes in vision, during treatment with this medicine as the Mounjaro 2.5mg Solution for Injection 0.5 ml may lead to complications of diabetic eye disease (retinopathy). When taking this medication, you may feel nauseous, sick (vomiting), or have diarrhoea. These adverse effects may result in dehydration (loss of fluids). You must consume enough water to avoid dehydration, especially if you have kidney issues.

No, after taking your dose, you should throw away any leftover medication. The vial is only intended for one usage, and reusing leftover medicines may result in infection or improper dosage.

To get the air bubbles to rise to the top, gently tap the syringe a few times. Then, push the plunger up gradually until the 0.5 mL mark is reached. By then, there shouldn't be any air bubbles in the syringe.

Mounjaro 2.5mg Solution for Injection 0.5 ml is not recommended during pregnancy, as it is unknown if it affects your unborn baby. If you are pregnant or planning pregnancy, inform your doctor before taking Mounjaro 2.5mg Solution for Injection 0.5 ml.

No, Mounjaro 2.5mg Solution for Injection 0.5 ml is not an Insulin. It is a GLP-1 and GIP receptor agonist that slows digestion, lowers glucagon levels, and increases insulin release to control blood sugar. Unlike insulin, Mounjaro 5mg Solution for Injection improves the body's natural reaction to food intake rather than taking the place of insulin.

Mounjaro 2.5mg Solution for Injection 0.5 ml is used to manage weight loss. Maintaining a proper diet and regular use of Mounjaro 2.5mg Solution for Injection 0.5 ml can enhance weight loss. It depends on individual factors how much weight can be reduced in 3 months. If you have concerns, please consult your doctor.

Mounjaro 2.5mg Solution for Injection 0.5 ml is administered as a weekly subcutaneous injection, which can be given in the abdomen, thigh, or upper arm. It should be injected on the same day each week, with or without food. To prevent irritation, change the injection site each time. Always use a fresh needle and syringe for each dose. Before using, ensure the solution is clear, colorless, and has not been frozen. Be sure to follow your doctor's guidance on the correct dosage and how to administer it.

Mounjaro 2.5mg Solution for Injection 0.5 ml aids weight loss by reducing appetite and helping you feel full longer, which leads to eating less. It works by mimicking two natural hormones in the body—GLP-1 and GIP—that help control hunger, blood sugar, and digestion. These hormones help regulate appetite and metabolism, contributing to both weight loss and better blood sugar control.

Mounjaro 2.5mg Solution for Injection 0.5 ml slows down the stomach's emptying, which may postpone the bloodstream's absorption of glucose. If this is used with a drug that causes hypoglycemia, this can result in dangerously low blood sugar levels.

Mounjaro 2.5mg Solution for Injection 0.5 ml should not be used by anyone who has had MTC or a family member who has Type 2 of the Multiple Endocrine Neoplasia Syndrome (MEN-2). It should not be used in people under 18 years of age. Additionally, anyone who has experienced severe tirzepatide allergic responses should not use it. It should be avoided by patients who have a history of gastroparesis, severe gastrointestinal disorders, or pancreatitis since it may exacerbate these diseases. Under medical supervision, people with severe liver or renal illness should use it with caution.

Country of origin

India

Manufacturer/Marketer address

Plot# 92, Sector 32, Institutional Area, Gurgaon-122001, Haryana, India
Other Info - MOU0066

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