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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

MPL XR-50 Tablet is used to treat high blood pressure (hypertension), heart-related chest pain (angina), irregular heart rhythm (arrhythmia), and to protect the heart after a heart attack (myocardial infarction). Besides this, it may also help in relieving symptoms of migraine-related headache and tremors (fits). It contains Metoprolol, which helps in slowing down the heart rate, making it easier for the heart to pump blood throughout the body. This lowers the blood pressure and helps in reducing the risk of having a stroke, heart attack, or other heart or kidney problems in the future. In some cases, it may cause certain common side effects like dizziness, tiredness, diarrhoea, stomach pain, nausea, and headache. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Whats That

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Composition :

METOPROLOL-50MG

Manufacturer/Marketer :

Sunij Pharma Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About MPL XR-50 Tablet

MPL XR-50 Tablet is used in the treatment of high blood pressure (hypertension), heart-related chest pain (angina), and irregular heart rhythm (arrhythmia). Hypertension is a lifelong or chronic condition in which the force exerted by the blood against the artery walls becomes so high that it leads to heart disease.

MPL XR-50 Tablet contains 'Metoprolol', which helps in slowing down the heart rate, making it easier for the heart to pump blood throughout the body. 

Not everyone who is taking MPL XR-50 Tablet will get these side effects. In some cases, MPL XR-50 Tablet may cause certain common side effects like dizziness, tiredness, diarrhoea, stomach pain, nausea, and headache. Most of these side effects do not require medical attention and resolve gradually over time. However, if the side effects are persistent, reach out to your doctor.

You can take MPL XR-50 Tablet with food or without food. It should be swallowed as a whole with a glass of water. Do not chew, bite, crush, or break it. Your doctor will advise you on how often you should take your tablets based on your medical condition. It is always important to complete your treatment course for better results.

Inform your doctor if you are allergic to MPL XR-50 Tablet . Also, let your doctor know if you have low blood pressure, asthma, overactive thyroid, metabolic acidosis, or severe blood circulation problems. Consult your doctor before taking MPL XR-50 Tablet if you are pregnant or breastfeeding. MPL XR-50 Tablet is not recommended for use in children. MPL XR-50 Tablet may cause dizziness, so drive with caution.

Uses of MPL XR-50 Tablet

MPL XR-50 Tablet is used in the treatment of High blood pressure (hypertension), prevention of heart-related chest pain (angina), heart rhythm disorder (arrhythmia), and heart attack (myocardial infarction). The detailed uses of MPL XR-50 Tablet are as follows:<br/>

  • Treatment of Hypertension: MPL XR-50 Tablet controls high blood pressure by reducing the heart rate and the force of contraction, thereby lowering blood pressure.<br/> 
  • Prevention of Heart-related Chest Pain: MPL XR-50 Tablet prevents chest pain (angina) by reducing the workload on the heart and improving blood flow to the heart muscle.<br/>
  • Control of Abnormal Heart Rhythms: MPL XR-50 Tablet helps manage irregular heartbeats (arrhythmias) by slowing the heart rate and stabilizing the heart's rhythm, reducing symptoms and improving heart function.<br/>
  • Management of Heart Attack: MPL XR-50 Tablet is used to manage heart attack (myocardial infarction) by reducing the workload on the heart and preventing further damage.<br/>

Directions for Use

• MPL XR-50 Tablet should be taken with or immediately after a meal for better absorption. • It is usually taken 2-3 times daily at the same time each day or as prescribed by your doctor. • Swallow MPL XR-50 Tablet as a whole with a glass of water. • Do not crush, chew, open, or break it.

Medicinal Benefits

  • MPL XR-50 Tablet  helps in slowing down the heart rate, making it easier for the heart to pump blood throughout the body.
  • This medicine lowers the blood pressure and helps in reducing the risk of having a stroke, heart attack, or other heart or kidney problems in the future.
  • MPL XR-50 Tablet may also help in relieving symptoms of migraine-related headache and tremors (fits).

How MPL XR-50 Tablet Works

MPL XR-50 Tablet contains 'Metoprolol', which helps in slowing down the heart rate, making it easier for the heart to pump blood throughout the body. This lowers the blood pressure and helps in reducing the risk of having a stroke, heart attack, or other heart or kidney problems in the future.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of MPL XR-50 Tablet

Do not take more than the prescribed dose of MPL XR-50 Tablet as it may cause overdose. The symptoms of overdose include slow heart rate, difficulty breathing, trembling or dizziness. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take MPL XR-50 Tablet if you are allergic to MPL XR-50 Tablet or any other beta-blockers.
  • Avoid taking MPL XR-50 Tablet if you have/had heart conduction, rhythm problems, uncontrolled/severe heart failure, blocked blood vessels, blood circulation problems, untreated pheochromocytoma, metabolic acidosis, low blood pressure, or prinzmetal angina.
  • Inform your doctor if you have asthma, COPD, diabetes, blood vessel disorder, slow heart rate, pheochromocytoma, myasthenia gravis, dry eye problems, kidney or liver impairment; if you are taking anti-depressants, other blood pressure-lowering medicines, or anti-arrhythmic agents.
  • Consult your doctor before taking MPL XR-50 Tablet if you are pregnant or breastfeeding.
  • MPL XR-50 Tablet is not recommended for children as safety and efficacy have not been established.
  • MPL XR-50 Tablet may cause dizziness, so drive with caution.
  • Don't stop taking MPL XR-50 Tablet without consulting your doctor. Suddenly stopping the use of MPL XR-50 Tablet may cause changes in your heart rhythm and blood pressure, cause chest pain, or a heart attack. Your doctor will gradually lower your dose to help prevent these symptoms.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with MPL XR-50 Tablet:
Co-administration of Disopyramide with MPL XR-50 Tablet can increase the side effects of disopyramide.

How to manage the interaction:
Although taking MPL XR-50 Tablet and Disopyramide together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience dizziness, fainting, palpitations, slow or fast pulse, or irregular heartbeats, consult a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with MPL XR-50 Tablet:
Taking Metoprolol with Ceritinib together increase the risk of abnormal heart rhythm.

How to manage the interaction:
Although there is a possible interaction between MPL XR-50 Tablet and Ceritinib, you can take these medicines together if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with MPL XR-50 Tablet:
Co-administration of Ritodrine with MPL XR-50 Tablet can decrease the effectiveness of both medications.

How to manage the interaction:
Although taking MPL XR-50 Tablet and Ritodrine together can cause an interaction, it can be taken if a doctor has suggested it. In case you experience any unusual symptoms, consult a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with MPL XR-50 Tablet:
Taking Metoprolol with Diltiazem together can cause increased side effects.

How to manage the interaction:
There may be a possibility of interaction between Diltiazem and MPL XR-50 Tablet, but it can be taken if prescribed by a doctor. However, if you notice fatigue, a headache, dizziness, swelling of the hands and feet, difficulty breathing, chest pain, an irregular heartbeat, make sure to contact a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with MPL XR-50 Tablet:
Taking MPL XR-50 Tablet with Theophylline, could make MPL XR-50 Tablet less effective and enhance the effects of Theophylline.

How to manage the interaction:
Although taking MPL XR-50 Tablet and theophylline together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as nausea, vomiting, insomnia, shaking of hands and legs, restlessness, uneven heartbeats, or difficulty breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with MPL XR-50 Tablet:
Using saquinavir together with metoprolol can increase the risk of an irregular heart rhythm

How to manage the interaction:
Co-administration of MPL XR-50 Tablet with Saquinavir can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with MPL XR-50 Tablet:
Taking Tizanidine with MPL XR-50 Tablet together can decrease blood pressure.

How to manage the interaction:
Although taking MPL XR-50 Tablet and Tizanidine together can cause an interaction, it can be taken if a doctor has suggested it. However, contact a doctor immediately if you experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. Do not stop using any medications without consulting a doctor.
How does the drug interact with MPL XR-50 Tablet:
Co-administration of verapamil with MPL XR-50 Tablet can increase the risk of side effects.

How to manage the interaction:
Although taking verapamil and MPL XR-50 Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as fatigue, headache, fainting, swelling of the extremities, weight gain, shortness of breath, chest pain, increased or decreased heartbeat, or irregular heartbeat, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with MPL XR-50 Tablet:
Co-administration of Clonidine and MPL XR-50 Tablet together may lower the blood pressure and slow the heart rate.

How to manage the interaction:
Although there is a possible interaction between Clonidine and MPL XR-50 Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience headaches, slow heartbeat, dizziness, contact a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with MPL XR-50 Tablet:
Taking MPL XR-50 Tablet with Atazanavir together can increase the risk of abnormal heart rhythm

How to manage the interaction:
Taking MPL XR-50 Tablet with Atazanavir together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do regular physical activity or exercise.
  • Opt for a diet rich in whole grains, fruits, vegetables, and low-fat dairy products.
  • Limit intake of sodium chloride (table salt) in your daily diet.
  • Quitting smoking is the best strategy to lower the risk of heart disease.
  • Avoid chronic stress as it can raise your blood pressure. 
  • Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Try to include heart-healthy omega-3 fatty acid-containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES
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Alcohol

Unsafe

Alcohol might increase the blood pressure-lowering effect of MPL XR-50 Tablet . It might also cause increased dizziness. Therefore, avoid alcohol consumption while taking MPL XR-50 Tablet .

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Pregnancy

Unsafe

MPL XR-50 Tablet is not recommended for use during pregnancy. If you are pregnant or planning for pregnancy, consult your doctor.

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Breast Feeding

Consult your doctor

MPL XR-50 Tablet may pass into breastmilk. Consult a doctor before taking MPL XR-50 Tablet if you are breastfeeding.

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Driving

Caution

MPL XR-50 Tablet may cause dizziness and tiredness. Therefore, drive or operate machinery only if you are alert.

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Liver

Consult your doctor

Dose adjustment may be needed. Consult your doctor before taking MPL XR-50 Tablet if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Dose adjustment may be needed. Consult your doctor before taking MPL XR-50 Tablet if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

MPL XR-50 Tablet is not recommended in children as the safety and efficacy have not been established.

Have a query?

FAQs

MPL XR-50 Tablet is indicated in the treatment of high blood pressure (hypertension), prevention of heart-related chest pain (angina), heart rhythm disorder (arrhythmia), and heart attack (myocardial infarction).

MPL XR-50 Tablet helps in slowing down the heart rate, making it easier for the heart to pump blood throughout the body. Thereby, lowers blood pressure.

Do not stop taking MPL XR-50 Tablet without consulting your doctor as it may lead to a rise in blood pressure. To treat your condition effectually, continue taking MPL XR-50 Tablet for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking MPL XR-50 Tablet .

Consult your doctor before taking MPL XR-50 Tablet if you have hyperthyroidism (overactive thyroid) as it might mask the symptoms or make it difficult to recognise the signs of thyrotoxicosis (excess thyroid hormone in the body).

Consult your doctor before taking MPL XR-50 Tablet with anti-diabetic medicines as it might mask the signs of low blood sugar. Regular monitoring of blood glucose levels while taking MPL XR-50 Tablet is advised.

Your doctor may probably ask you to stop taking MPL XR-50 Tablet 24hours prior to the surgery, as it might lower blood pressure when combined with general anaesthesia. If you are due to have any surgery or are receiving an anaesthetic, inform the doctor that you are taking MPL XR-50 Tablet .

Taking MPL XR-50 Tablet along with multivitamin/multimineral supplements may decrease the effect of MPL XR-50 Tablet . Therefore, maintain a gap of at least 2 hours between both. However, you are advised to take MPL XR-50 Tablet with other medicines only after consulting your doctor.

High blood pressure increases the workload on the arteries and heart. If untreated, it could damage the blood vessels of the heart, brain, and kidney and might result in stroke, heart failure or kidney failure. Hypertension increases the risk of heart attacks. Therefore, anti-hypertensives such as MPL XR-50 Tablet are used to lower the blood pressure to normal; this reduces the risk of developing these disorders.

Yes, MPL XR-50 Tablet contains metoprolol which belongs to a group of medicines called beta-blockers.

No, MPL XR-50 Tablet is not a blood thinner. It is an antihypertensive medicine.

MPL XR-50 Tablet starts working within 2 hours. However, it can take up to a week to show its full effect.

No, it is not dangerous to take MPL XR-50 Tablet . It is safe to take MPL XR-50 Tablet if prescribed by the doctor.

MPL XR-50 Tablet may cause sleepiness. Drive or operate machinery only if you are alert. Consult the doctor if you have sleep problems.

Alcohol might increase the blood pressure-lowering effect of MPL XR-50 Tablet . It might also cause increased dizziness. Therefore, avoid alcohol consumption while taking MPL XR-50 Tablet .

MPL XR-50 Tablet may cause side effects like dizziness, tiredness, diarrhoea, stomach pain, nausea, and headache. If the side effects are persistent, reach out to your doctor.

Country of origin

India

Manufacturer/Marketer address

T-1/B National Park, Gulbai Tekra, Ahmedabad ? 380 015, (India)
Other Info - MPL0006

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