Apollo
logo
0

Welcome User

Login/Sign Up

Home
Buy Medicines
Lab Tests
Doctor Consult
Circle Membership
insurance
Blogs
Contact Us
Privacy Policy
Return & Refunds
Need Help
Terms and Conditions
Select Delivery Location
compositionComposition:MELPHALAN-50MG
prescription
Prescription Medicine
info
image icons

Myelostem 50 Injection is used to treat Multiple myeloma, advanced cancer of the ovaries, childhood neuroblastoma (cancer of the nervous system), malignant melanoma (skin cancer) and soft tissue sarcoma. It contains Melphalan, which reduces the number of abnormal cells your body makes. Thus, it treats cancer efficiently. The most common adverse reactions observed in patients treated with this medicine are neutrophil count decreased, white blood cell count decreased, platelet count decreased, lymphocyte count decreased, diarrhoea, fatigue, anaemia, nausea, vomiting and hypokalemia.

Read more
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
OffersOffers & Discounts

Get Free delivery (₹99) with circle icon

Join Circle
coupon
Get 18% Off with Coupons
coupon
Extra 10% Off with Bank Offers
bank offer
bank offer
bank offer

More about the Product

Composition :

MELPHALAN-50MG

Manufacturer/Marketer :

Halsted Pharma Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Myelostem 50 Injection

Myelostem 50 Injection is an injectable prescription medicine used primarily to treat multiple myeloma, which is a type of cancer that affects plasma cells in the bone marrow. It is also used to treat advanced ovarian cancer when other treatments are no longer suitable. This medication works by targeting and slowing the growth of abnormal cells in your body.

Because it is given directly into a vein, it is scheduled in treatment cycles rather than taken daily. Keeping all of your scheduled clinical appointments is critical to ensure the medication works consistently. During your treatment cycles, drinking plenty of water and maintaining a balanced, nutrient-rich diet can support your body's recovery.

Like many cancer treatments, this medicine can cause common side effects such as nausea, temporary hair loss, and low blood cell counts. Please contact your doctor right away if you experience serious side effects, such as signs of a severe infection, unexpected bruising, or sudden breathing difficulties.

Talk to your doctor before starting this treatment if you have kidney disease, a weakened immune system, or existing low blood counts. Do not take this if you have had a severe allergic reaction to this medicine or any of its ingredients in the past.

This medicine can interact with other treatments, including live vaccines, which can lead to severe infections because your immune system will be weakened. It is also important to consult your healthcare provider if you are pregnant, planning to become pregnant, breastfeeding, or if you are an older adult, as specific safety precautions are required for these groups.

Uses of Myelostem 50 Injection

Your doctor may recommend this injection to help manage the following conditions:

  • Multiple Myeloma: It helps by destroying abnormal plasma cells in the bone marrow. It is often used in high doses to clear out these abnormal cells before a stem cell transplant.
  • Ovarian Cancer: It is used to treat advanced cancer of the ovaries, helping to slow down or stop the progression of the disease when other therapies have not worked.

Key Benefits

When taken consistently as directed, this medicine may provide the following health benefits:

  • Helps control cancer growth: It helps target rapidly multiplying cancer cells, which may help control the spread of the disease and may lead to a period of remission.
  • Prepares for stem cell transplant: For patients undergoing a stem cell transplant, this medicine helps clear the bone marrow, making room for healthy new cells to grow and rebuild the immune system.
  • May help relieve symptoms: By helping control the growth of abnormal cells, this medicine may help relieve symptoms associated with multiple myeloma and ovarian cancer, such as bone pain or extreme fatigue.
Side effects of Myelostem 50 Injection

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Myelostem 50 Injection will be administered by a healthcare professional.
  • Do not self-administer it.

How Myelostem 50 Injection Works

Myelostem 50 Injection belongs to a class of medicines known as alkylating agents. It works by binding directly to the DNA inside cancer cells. This action damages the cells' genetic blueprint, preventing them from copying their DNA and multiplying. Because cancer cells grow and divide much faster than normal cells, they are highly sensitive to this DNA damage, which ultimately causes them to break down and die.
bannner image

Alcohol

Caution

Avoid alcohol consumption while on treatment with Myelostem 50 Injection.

bannner image

Pregnancy

Caution

Myelostem 50 Injection should not be used during pregnancy. So, inform your doctor if you are pregnant or suspect pregnancy. You or your partner must use a reliable form of contraception to prevent pregnancy while taking these medications.

bannner image

Breast Feeding

Caution

If you are breastfeeding, inform your doctor. You should not breastfeed while on treatment with Myelostem 50 Injection.

bannner image

Driving

Caution

It is unknown whether Myelostem 50 Injection alters the ability to drive, so do not drive or operate machinery if you experience any symptoms affecting your ability to concentrate and react.

bannner image

Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before taking Myelostem 50 Injection.

bannner image

Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before taking Myelostem 50 Injection. Your doctor may titrate the dose if required based on your condition.

bannner image

Children

Caution

Myelostem 50 Injection is only not recommended for use in children as the safety and effectiveness have not been established.

bannner image

Heart

Caution

Myelostem 50 Injection should be avoided in heart patients, especially those with a history of arrhythmias or cardiac dysfunction, due to its potential for cardiotoxicity and thromboembolic risks. If absolutely necessary, it must be administered under strict medical supervision with full cardiac monitoring.

bannner image

Geriatrics

Caution

Myelostem 50 Injection may be used in geriatric patients, as studies have not shown age-specific limitations to its effectiveness. However, older adults often have reduced liver, kidney, or heart function, so cautious dosing and close monitoring are essential to minimize toxicity.

What if I have taken an overdose of Myelostem 50 Injection

Because this medicine is prepared and given by trained medical professionals, an overdose is extremely rare. If you suspect you have received too much of this medicine, or if you experience severe side effects immediately after an infusion, notify your healthcare team.

Diet & Lifestyle Advise

  • Stay Hydrated: Drink plenty of water and clear fluids throughout your treatment cycle, unless your doctor tells you otherwise. This helps your kidneys flush the medicine out of your body safely.
  • Practice Gentle Mouth Care: To prevent or soothe mouth sores, use a soft-bristled toothbrush and rinse your mouth with a mild, alcohol-free mouthwash or a simple saltwater solution several times a day.
  • Avoid Infections: Wash your hands frequently with soap and water. Stay away from crowded areas and avoid close contact with people who have active infections, cold symptoms, or the flu, as your body's defences will be lowered.
  • Eat Small, Frequent Meals: If you experience nausea, try eating smaller portions of bland foods throughout the day rather than three large meals.
health query

Have a query?

How Soon It Starts Working

The time required for Myelostem 50 Injection to start to work: The time required for Myelostem 50 Injection to show its action is unknown. The time for which the effects of Myelostem 50 Injection last: The duration of action for Myelostem 50 Injection is unknown.

What if you forget to take Myelostem 50 Injection

Since this medicine is injected by a healthcare professional in a clinic, it is highly unlikely that you will miss a dose. However, if you miss a scheduled appointment for your infusion, contact your doctor or clinic immediately to reschedule your treatment.

Storage

•Because it is a parenteral injection given in a clinical setting, the healthcare facility will store and handle the medication.

Drug Warnings

  • Additional medicines: Your doctor may prescribe anti-nausea medicines or other supportive treatments alongside medicine to help prevent or manage side effects during treatment.
  • Keep all monitoring appointments: Your doctor will schedule regular blood tests to check your blood cell counts and kidney function. If you receive long-term treatment, your lung function may also be monitored to help detect side effects early.
  • Risk of secondary blood cancers: Long-term treatment may slightly increase the risk of developing certain blood cancers, such as acute myeloid leukaemia (AML) or myelodysplastic syndrome (MDS). Your doctor will monitor your health during and after treatment.
  • Long-term lung effects: Rarely, long-term treatment may affect the lungs. Tell your doctor if you develop a persistent cough or shortness of breath during or after treatment.
  • Contraindication: Do not receive it if you are allergic to it or any of its ingredients. Your doctor may also delay, avoid, or choose an alternative treatment if you have a severe active infection, very low blood cell counts (severe bone marrow suppression), or if your cancer has previously not responded to medicine.

Drug-Drug Interactions

verifiedApollotooltip
  • Cyclosporine: Taking this medicine with cyclosporine may increase the risk of kidney problems.
  • Medicines that lower blood cell counts: Taking this medicine with other medicines that reduce blood cell counts (such as some chemotherapy medicines) may increase the risk of infections and bleeding.
  • Live vaccines: Do not receive live vaccines while taking this medicine unless your doctor advises you to, as they may increase the risk of serious infections.
  • Previous treatment failure: Your doctor may not recommend Myelostem 50 Injection if your cancer has previously not responded to treatment with this medicine.
MelphalanYellow fever vaccine
Critical
MelphalanBCG vaccine
Critical

Drug-Drug Interactions

Login/Sign Up

MelphalanYellow fever vaccine
Critical
How does the drug interact with Myelostem 50 Injection:
Co-administration of the Yellow fever vaccine with Myelostem 50 Injection can increase the risk or severity of infection or reduces the effectiveness of the vaccine.

How to manage the interaction:
Taking Myelostem 50 Injection with the Yellow fever vaccine is not recommended, but it can be taken if prescribed by the doctor. Do not stop using any medication without consulting your doctor.
MelphalanBCG vaccine
Critical
How does the drug interact with Myelostem 50 Injection:
Co-administration of the BCG vaccine with Myelostem 50 Injection together can increase the risk or severity of infection or reduces the effectiveness of the vaccine.

How to manage the interaction:
Taking Myelostem 50 Injection with the BCG vaccine is not recommended, but it can be taken if prescribed by the doctor. Do not stop using any medication without consulting your doctor.
MelphalanLeflunomide
Severe
How does the drug interact with Myelostem 50 Injection:
Co-administration of Myelostem 50 Injection with Leflunomide together can increase the risk of infections.

How to manage the interaction:
Although taking Leflunomide and Myelostem 50 Injection together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
MelphalanNalidixic acid
Severe
How does the drug interact with Myelostem 50 Injection:
Co-administration of Nalidixic acid with Myelostem 50 Injection together can increase the risk or severity of side effects.

How to manage the interaction:
Although taking Myelostem 50 Injection and Nalidixic acid together can evidently cause an interaction, it can be taken if your doctor has suggested it. However contact a doctor immediately, if you experience any symptoms such as easy bruising or bleeding, unusual weakness, nausea, stomach pain, low fever, or loss of appetite. Do not discontinue any medications without consulting a doctor.
MelphalanAdalimumab
Severe
How does the drug interact with Myelostem 50 Injection:
Co-administration of Adalimumab with Myelostem 50 Injection together can increase the risk and severity of infection.

How to manage the interaction:
Although taking Myelostem 50 Injection and Adalimumab together can evidently cause an interaction, it can be taken if a doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
MelphalanInfliximab
Severe
How does the drug interact with Myelostem 50 Injection:
Co-administration of Infliximab with Myelostem 50 Injection can increase the serious infection.

How to manage the interaction:
There may be a possibility of interaction between Myelostem 50 Injection and Infliximab, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
MelphalanNatalizumab
Severe
How does the drug interact with Myelostem 50 Injection:
Co-administration of Myelostem 50 Injection with Natalizumab can increase the risk and severity of infection.

How to manage the interaction:
Taking Myelostem 50 Injection with Natalizumab together can possibly result in an interaction, but it can be taken if your doctor has advised it. It is important to contact a doctor if you experience any symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain, burning during urination, weakness on one side of the body, vision problems, or confusion. Do not stop using any medications without a doctor's advice.
MelphalanThalidomide
Severe
How does the drug interact with Myelostem 50 Injection:
Co-administration of Thalidomide together with Myelostem 50 Injection may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Myelostem 50 Injection together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
MelphalanFingolimod
Severe
How does the drug interact with Myelostem 50 Injection:
Co-administration of Fingolimod and Myelostem 50 Injection can increase the risk of infection.

How to manage the interaction:
There may be a possibility of interaction between Myelostem 50 Injection and Fingolimod, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
MelphalanBaricitinib
Severe
How does the drug interact with Myelostem 50 Injection:
Co-administration of Baricitinib and Myelostem 50 Injection together can raise the risk of serious infections.

How to manage the interaction:
Although there is an interaction, Baricitinib can be taken with Myelostem 50 Injection if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with Myelostem 50 Injection when used as directed. 
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[CHEMOTHERAPY]

FAQs

Myelostem 50 Injection is used to treat Multiple myeloma, advanced cancer of the ovaries, childhood neuroblastoma (cancer of the nervous system), malignant melanoma (skin cancer) and soft tissue sarcoma.
Myelostem 50 Injection contains Melphalan, which works by reducing the number of abnormal cells your body makes. Thus, it treats cancer efficiently.
While taking Myelostem 50 Injection, make sure to attend all of your doctor's appointments to ensure the therapy is effective. Blood tests and weight checks must be monitored on a regular basis. Both men and women should utilize an effective method of contraception while taking Myelostem 50 Injection.
Melphalan can cause a significant decrease in the number of blood cells and platelets. Your doctor may suggest laboratory tests before and during the treatment.
This medicine is injected or infused directly into a vein by a trained healthcare professional in a hospital or clinic setting. It is not designed to be taken or self-injected at home. Talk to your doctor if you have questions about your infusion schedule.
Yes, temporary hair thinning or complete hair loss is a common side effect of this medicine. Hair typically begins to grow back after the treatment cycles are completed. Talk to your doctor for advice on managing hair loss.
No, you should not become pregnant while receiving this medicine, as it can cause serious harm to an unborn baby. Both men and women should use effective birth control during treatment. If you plan to have children in the future, talk to your doctor about fertility preservation options before starting it, as it may affect fertility.
This medicine can lower the number of healthy cells in your blood, including red blood cells, white blood cells, and platelets. Regular blood tests help your doctor ensure it is safe to proceed with your next treatment cycle. Talk to your doctor to learn more.
Your risk of infection is usually highest about 2 to 3 weeks after treatment, when your white blood cell count may be at its lowest. Follow your doctor's advice and contact them immediately if you develop a fever, chills, or other signs of infection.
When used in high doses before a stem cell transplant, this medicine helps clear out the abnormal cells in your bone marrow. This prepares your body to receive and grow the healthy new stem cells. Talk to your doctor for more details about your transplant plan.
You should avoid receiving live vaccines during your treatment, as your immune system will be weakened and you could develop an infection from the vaccine. Always check with your doctor before getting any immunisation.
A fever can be a sign of a serious infection, which can be dangerous when your white blood cell count is low. If your temperature rises, contact your doctor or seek emergency medical care immediately.
Yes, this medicine can cause inflammation of the mouth lining, leading to painful mouth sores. Practising gentle oral hygiene and staying hydrated can help manage this side effect. Talk to your doctor if the sores make it hard to eat or drink.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India
Other Info - MYE0027
whatsapp Floating Button
Buy Now