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  3. Mylocar 60 mg Injection 1's

Mylocar 60 mg Injection 1's, Pack of 1 Injection
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Mylocar 60 mg Injection is used to treat Multiple Myeloma. It contains Carfilzomib, which suppresses proteasomes that prevent protein breakdown in MM (multiple myeloma) cells. When proteasome function is stopped within the MM cell, a protein build-up occurs within the MM cell, which destroys the malignant cells. Sometimes, Mylocar 60 mg Injection may cause side effects such as fatigue (feeling overtired), anaemia, nausea, thrombocytopenia (low platelet level), dyspnea (feeling short of breath), diarrhoea, and pyrexia (fever).

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Composition :

CARFILZOMIB-60MG

Manufacturer/Marketer :

BDR Pharmaceuticals Internationals Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Mylocar 60 mg Injection

Mylocar 60 mg Injection belongs to the group of proteasome inhibitors (anti-cancer medicines). It is used alone and in combination with other medications to treat people with multiple myeloma (a type of cancer of the bone marrow) who have already been treated with other medicines. Multiple myeloma, also known as myeloma, is a type of bone marrow cancer that affects several areas of the body, such as the spine, skull, pelvis, and ribs.

Mylocar 60 mg Injection contains Carfilzomib, which suppresses proteasomes that prevent protein breakdown in MM (multiple myeloma) cells. When proteasome function is stopped within the MM cell, a protein build-up occurs within the MM cell, which destroys the malignant cells.

Mylocar 60 mg Injection is administered in a hospital setting by a physician qualified by training and experience to administer cancer chemotherapeutic agents. Sometimes, you may experience common side effects, such as fatigue (feeling overtired), anaemia, nausea, thrombocytopenia (low platelet level), dyspnea (feeling short of breath), diarrhoea, and pyrexia (fever). Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if any of these side effects persist or worsen.

Before taking the Mylocar 60 mg Injection, inform your doctor about all your allergic or hypersensitivity reactions to medicines or food. Mylocar 60 mg Injection can cause fetal harm when administered to a pregnant woman. It is critical not to become pregnant while undergoing therapy and for several months afterwards. Before beginning treatment, discuss effective contraception with your healthcare professional. Inform them immediately if you or your partner becomes pregnant while undergoing therapy. Breastfeeding is usually not advised during this treatment since it is unknown whether this medication passes into breast milk. Do not skip any laboratory checks because Thrombocytopenia, Hepatic Toxicity and Hepatic Failure may occur. If it happens, reduce or interrupt dosing as clinically indicated.

Uses of Mylocar 60 mg Injection

Mylocar 60 mg Injection is used in the treatment of Multiple Myeloma. The detailed uses of Mylocar 60 mg Injection are as follows:<br/>• Relapsed or refractory multiple myeloma: Mylocar 60 mg Injection is used for the treatment of multiple myeloma in adult patients whose cancer has relapsed or is refractory to one or more lines of therapy. It is specifically indicated when the disease becomes resistant to previous treatments, helping to slow disease progression and extend survival. By targeting cancer cells that have adapted to earlier therapies, Mylocar 60 mg Injection provides a critical second-line or later treatment option.<br/>• Combination therapy support: Mylocar 60 mg Injection is used in combination with other agents such as dexamethasone or lenalidomide to enhance overall treatment efficacy in patients with relapsed or refractory multiple myeloma. These combinations have shown improved response rates and longer progression-free survival compared to monotherapy. The synergy between Mylocar 60 mg Injection and these medications helps increase cancer cell death while maintaining manageable toxicity profiles.<br/>• Proteasome inhibition in cancer therapy: Mylocar 60 mg Injection is used as a selective proteasome inhibitor that blocks the activity of proteasomes, which are cellular structures responsible for breaking down unneeded or damaged proteins. In cancer cells, this inhibition disrupts protein homeostasis and causes toxic proteins to accumulate, leading to cellular stress and programmed cell death (apoptosis). By targeting the increased protein turnover demands of myeloma cells, Mylocar 60 mg Injection effectively eliminates cancer cells while leaving most normal cells relatively unaffected.<br/>

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication.• Mylocar 60 mg Injection will be administered by a doctor or nurse in a healthcare facility.• Do not self-administer.

Medicinal Benefits

Carfilzomib, a proteasome inhibitor, is present in Mylocar 60 mg Injection. It suppresses proteasomes, preventing protein breakdown in MM (multiple myeloma) cells. When proteasome function is stopped within the MM cell, a protein build-up occurs within the MM cell, which destroys the malignant cells.

How Mylocar 60 mg Injection Works

Mylocar 60 mg Injection contains Carfilzomib, which suppresses proteasomes that prevent protein breakdown in MM (multiple myeloma) cells. When proteasome function is stopped within the MM cell, a protein build-up occurs within the MM cell, which destroys the malignant cells.

Storage

• Store in a cool and dry place away from sunlight.• Keep Mylocar 60 mg Injection out of reach and sight of children.• Cold chain - To be stored in cold places at 2ºC to 8ºC.
Side effects of Mylocar 60 mg Injection
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
Here's a comprehensive approach to managing medication-triggered high blood pressure (hypertension):
  • Inform your doctor if you experience high blood pressure symptoms after starting a new medication or changing your medication regimen.
  • To reduce high blood pressure symptoms, your doctor may change your medication regimen or dose.
  • Monitor your blood pressure regularly to track changes and potential side effects.
  • Make lifestyle changes, such as following a healthy diet, exercising regularly, and reducing sodium intake.
  • Consider incorporating stress-reducing activities, like meditation or deep breathing exercises, into your daily routine.
  • Create a personalized plan with your doctor to manage high blood pressure, which may include additional medications, therapies, or lifestyle modifications.
  • Follow up with your doctor on a frequent basis to assess progress, change treatment plans, and address any concerns or issues.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):
  • Tell your doctor immediately if you experience shortness of breath after taking medication.
  • Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
  • Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
  • For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
  • Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
  • Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
  • Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

What if I have taken an overdose of Mylocar 60 mg Injection

As Mylocar 60 mg Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away. Overdose of Mylocar 60 mg Injection may cause chills, dizziness, and decreased urination.

Drug Warnings

Before taking Mylocar 60 mg Injection, inform your doctor about your medical history and other medications you are currently taking to rule out any potential negative effects. Avoid taking Mylocar 60 mg Injection if you are pregnant or breastfeeding or allergic to any component present in Mylocar 60 mg Injection. Both women and men using this Mylocar 60 mg Injection should use birth control to avoid pregnancy. Inform your doctor right away if you or your partner become pregnant during treatment with Mylocar 60 mg Injection. Inform your doctor if you have a history of heart failure and ischemia, Pulmonary Hypertension, Thrombocytopenia, low blood pressure or hepatic toxicity; your doctor will closely monitor and manage it. Carfilzomib injection may induce serious or life-threatening responses for up to 24 hours following administration. Before each dose of carfilzomib, you will be given specific drugs to assist in preventing a reaction. If you develop any of the following symptoms after your treatment, contact your doctor right away: fever, chills, joint or muscle pain, flushing or swelling of the face, swelling or tightening of the throat, vomiting, weakness, shortness of breath, disorientation or fainting, or chest tightness or pain.

Drug-Drug Interactions

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CarfilzomibConjugated Estrogens
Severe
CarfilzomibEltrombopag
Severe

Drug-Drug Interactions

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CarfilzomibConjugated Estrogens
Severe
How does the drug interact with Mylocar 60 mg Injection:
Combining Mylocar 60 mg Injection with Conjugated Estrogens can increase the risk of developing blood clots.

How to manage the interaction:
Although taking Conjugated estrogen and Mylocar 60 mg Injection together can result in an interaction, it can be taken if prescribed by a doctor. However, if you experience chest discomfort, shortness of breath, weakness, or blurred vision, consult a doctor. Do not stop using any medications without consulting a doctor.
CarfilzomibEltrombopag
Severe
How does the drug interact with Mylocar 60 mg Injection:
Coadministration of Eltrombopag with Mylocar 60 mg Injection can increase the risk or severity of blood clots that can lead to complications such as heart attack, pulmonary embolism (blockage of an artery in the lung), and stroke.

How to manage the interaction:
Although taking Eltrombopag and Mylocar 60 mg Injection together can cause an interaction, it can be taken if your doctor has suggested it. If you notice any of these signs, chest pain, difficulty breathing, coughing up blood, sudden vision loss, pain, redness, swelling in an arm or leg, or weakness on one side of your body it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice.
CarfilzomibTestosterone
Severe
How does the drug interact with Mylocar 60 mg Injection:
The combined use of Testosterone and Mylocar 60 mg Injection can increase the risk of blood clots.

How to manage the interaction:
Co-administration of Testosterone and Mylocar 60 mg Injection can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
CarfilzomibPrasterone
Severe
How does the drug interact with Mylocar 60 mg Injection:
Taking Prasterone with Mylocar 60 mg Injection can increase the risk of clotting.

How to manage the interaction:
Co-administration of Prasterone with Mylocar 60 mg Injection can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience sudden loss of eyesight, chest pain, breathing difficulties, coughing up blood, pain, redness, or swelling in an arm or leg, and numbness or weakness on one side of the body, consult a doctor, immediately. Do not stop using any medications without a doctor's advice.
CarfilzomibClozapine
Severe
How does the drug interact with Mylocar 60 mg Injection:
Combining Mylocar 60 mg Injection with Clozapine can increase the risk of neutropenia.

How to manage the interaction:
Co-administration of Clozapine with Mylocar 60 mg Injection can possibly result in an interaction, but it can be taken if your doctor has advised it. If you experience any of the following symptoms, contact your doctor immediately: severe infection, fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, or pain or burning when urinating. Do not discontinue any medications without consulting a doctor.
CarfilzomibDesogestrel
Severe
How does the drug interact with Mylocar 60 mg Injection:
Mylocar 60 mg Injection can occasionally cause dangerous blood clots and using it together with ethinyl estradiol may increase the risk.

How to manage the interaction:
Co-administration of Desogestrel with Mylocar 60 mg Injection can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any symptoms like rapid loss of eyesight, chest pain, shortness of breath, breathing difficulties, coughing up blood, pain, redness, or swelling in an arm or leg, and numbness or weakness on one side of the body, contact a doctor. Do not stop using any medications without a doctor's advice.
CarfilzomibEstradiol
Severe
How does the drug interact with Mylocar 60 mg Injection:
Mylocar 60 mg Injection can cause serious blood clots and taking it alongside estradiol may enhance the risk.

How to manage the interaction:
Co-administration of Estradiol with Mylocar 60 mg Injection can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience symptoms like chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness, or swelling in an arm or leg, or numbness or weakness on one side of the body, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
CarfilzomibStanozolol
Severe
How does the drug interact with Mylocar 60 mg Injection:
Coadministration of Mylocar 60 mg Injection and sulfasalazine can increase the risk or severity of developing blood clots.

How to manage the interaction:
Although taking Mylocar 60 mg Injection and sulfasalazine together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness, or swelling in an arm or leg, and numbness or weakness on one side of the body, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
CarfilzomibLevonorgestrel
Severe
How does the drug interact with Mylocar 60 mg Injection:
Mylocar 60 mg Injection can occasionally cause dangerous blood clots and using it together with levonorgestrel may increase the risk.

How to manage the interaction:
Co-administration of Mylocar 60 mg Injection with Levonorgestrel can result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these signs, it's important to contact a doctor right away: blood clots that can be harmful, high blood pressure or cholesterol, heart problems like heart attack or blockage in the lung, stroke, complications, chest pain, difficulty breathing, coughing up blood, sudden vision loss, pain, redness, or swelling in an arm or leg, and numbness or weakness on one side of your body. Do not discontinue any medications without consulting a doctor.
CarfilzomibTamoxifen
Severe
How does the drug interact with Mylocar 60 mg Injection:
Taking Mylocar 60 mg Injection with tamoxifen may increase the risk of blood clots. The risk is also increased with age, cigarette smoking, high blood pressure, or high cholesterol.

How to manage the interaction:
Although taking tamoxifen and Mylocar 60 mg Injection together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not stop using any medications without consulting doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Mylocar 60 mg Injection Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Avoid alcohol consumption while on treatment with Mylocar 60 mg Injection.

bannner image

Pregnancy

Unsafe

Mylocar 60 mg Injection should not be taken during pregnancy as it might cause fetal harm. Inform your doctor immediately if you are conceiving while on therapy.

bannner image

Breast Feeding

Unsafe

Do not breastfeed while you are receiving Mylocar 60 mg Injection and for two weeks after your final dose.

bannner image

Driving

Caution

Mylocar 60 mg Injection may cause fatigue, dizziness, fainting, and/or a drop in blood pressure. So, if you have any of these symptoms while in therapy, you should not operate machinery or drive a car.

bannner image

Liver

Caution

Extreme caution is exercised while using Mylocar 60 mg Injection in patients with liver impairment. Inform your doctor if you have liver impairment. Your doctor monitors liver enzymes and withholds dosing if suspected.

bannner image

Kidney

Caution

Limited information is available. Please inform your doctor before prescribing Mylocar 60 mg Injection if you have kidney impairment. Your doctor will weigh the benefits and potential risks before prescribing Mylocar 60 mg Injection.

bannner image

Children

Caution

The safety and effectiveness of Mylocar 60 mg Injection in pediatric patients have not been established.

Have a query?

FAQs

Mylocar 60 mg Injection is used to treat Multiple Myeloma.

Mylocar 60 mg Injection contains Carfilzomib, which inhibits proteasomes and thereby prevents protein breakdown in MM (multiple myeloma) cells. When the proteasome action within the MM cell is disturbed, a protein accumulation occurs, destroying the cancerous cells.

No, it is unsafe to father a child while taking Mylocar 60 mg Injection. It is recommended for sexually active men to use condoms while on treatment and for at least several months after their last dose of Mylocar 60 mg Injection.

Based on the medical condition, Mylocar 60 mg Injection may be given alone or together with other medicines used to treat multiple myeloma.

Tell your healthcare professional immediately if you get any signs of an infusion-related reaction during or after the infusion. Your doctor may give other medicines, or the infusion may need to be slowed down or stopped.

Mylocar 60 mg Injection can cause a significant decrease in the number of blood cells and platelets. Your doctor may suggest laboratory tests before and during the treatment. Tell your healthcare provider if you develop a fever or have signs of bruising or bleeding.

Mylocar 60 mg Injection treats multiple myeloma that has returned or no longer responds to treatment. It's often used with other medications. If you have questions or concerns, talk to your doctor. They will help you understand if Mylocar 60 mg Injection is right for you.

Mylocar 60 mg Injection is to be administered by intravenous infusion in a hospital setting under the supervision of a physician qualified to administer cancer chemotherapeutic agents.

Mylocar 60 mg Injection is given on two consecutive days each week for three weeks followed by a 12-day rest period or it may be given once a week for 3 weeks followed by a 13-day rest period. However, the pattern and duration of treatment may vary. Please consult the doctor if you have any concerns.

You may experience nausea and extreme tiredness from Mylocar 60 mg Injection. To cope with nausea, try eating small meals, avoiding strong smells, and staying hydrated. For tiredness, prioritize rest, break tasks into smaller chunks, and take regular breaks. Practice relaxation techniques like deep breathing, meditation, or yoga, and stay hydrated and energized with nutritious food. However, if these are bothering you consult your doctor immediately.

Mylocar 60 mg Injection can lower your blood cell and platelet counts, increasing the risk of infections, anemia, and bleeding. To keep an eye on this, your doctor will likely order regular blood tests before and during treatment. Consult your doctor if you suspect any symptoms of low immunity like delayed healing or frequent infections.

If you experience any of the following, seek a doctor's advice right away: fever, infection signs, unusual bleeding, shortness of breath, chest pain, severe nausea, weakness, confusion, or severe headache. Also, consult your doctor if you have concerns or questions about your treatment, notice any health changes or side effects, miss a dose, or need to change your treatment schedule.

Mylocar 60 mg Injection should not be taken during pregnancy as it might cause fetal harm. Inform your doctor immediately if you are pregnant or think you may be pregnant while on therapy.

Do not breastfeed while you are receiving Mylocar 60 mg Injection and for two weeks after your final dose as it may pass into the breastmilk. Consult your doctor if you have any concerns regarding it.

Country of origin

India

Manufacturer/Marketer address

407-408, Sharda Chambers, New Marine Lines, Mumbai 400 020 (Maharashtra), New Marine Lines, Marine Lines, Mumbai, Maharashtra 400020
Other Info - MYL0093

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 7:05 AM IST

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Reference

  1. https://www.cancer.gov/research/participate/clinical-trials/intervention/carfilzomib#:~:text=Carfilzomib%20works%20by%20blocking%20the,that%20kills%20the%20cancerous%20cells.
  2. https://www.cdc.gov/cancer/myeloma/index.htm
  3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/202714lbl.pdf
  4. https://www.cancerresearchuk.org/about-cancer/treatment/drugs/carfilzomib-dexamethasone
  5. https://medlineplus.gov/druginfo/meds/a612031.html#:~:text=Carfilzomib%20is%20in%20a%20class,cancer%20cells%20in%20your%20body.
  6. https://ashpublications.org/blood/article/121/6/893/31397/Carfilzomib

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