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Myo Pyrolate Injection 5 ml is used to reverse the effects of muscle relaxants and anaesthesia medicines used during surgery. It contains Glycopyrrolate and Neostigmine which increase the level of an enzyme that is involved in transmission between nerve impulses and muscle movements. In some cases, this medicine may cause side effects such as constipation, dry mouth, nausea, vomiting, dizziness, diarrhoea, and dry skin. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Neon Laboratories Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Myo Pyrolate Injection 5 ml

Myo Pyrolate Injection 5 ml is a prescription injection used at the end of surgery to reverse the effects of certain muscle-relaxing medicines. It helps restore normal muscle strength, swallowing, and breathing before you wake up. This allows for a smoother, safer transition as you recover from anaesthesia.

Because this medication is used in a hospital or surgical setting, it is given as an injection by a healthcare professional. You do not need to worry about a regular schedule or taking it with food, but your medical team will monitor your recovery closely. Following simple post-surgery guidelines like resting and drinking small sips of water can help support your body's recovery process.

While Myo Pyrolate Injection 5 ml is generally safe, some patients may experience temporary side effects like a dry mouth, mild nausea, or a fast heart rate. If you experience severe dizziness, difficulty breathing, or extreme muscle weakness after your surgery, tell your healthcare team immediately.

Talk to your doctor before surgery if you have a history of asthma, heart disease, or bowel obstructions. This medicine should not be given to individuals with known allergies to its ingredients or those with certain physical blockages in the stomach, gut, or urinary tract.

It can interact with other drugs such as certain blood pressure medicines, which can change how your body responds to the treatment. Pregnant, breastfeeding, or elderly individuals should consult their doctor regarding its safe use.

Uses of Myo Pyrolate Injection 5 ml

Your doctor may prescribe this medicine to treat several conditions, including:

  • Reversing muscle relaxation after surgery: Myo Pyrolate Injection 5 ml helps wake up your muscles and restores normal breathing and swallowing after you have been given muscle-relaxing drugs during an operation.
  • Preventing unwanted side effects: It helps control and prevent a dangerously slow heart rate and excess saliva production that can happen when reversing surgical muscle relaxants.

Key Benefits

Myo Pyrolate Injection 5 ml helps reverse the effects of certain muscle relaxants used during surgery, allowing your muscles to regain normal function so you can breathe on your own after anaesthesia. Its combination of active ingredients restores muscle strength while reducing unwanted side effects. Key benefits include:

  • Restores Normal Muscle Function: This medication reverses the effects of muscle relaxants used during surgery, helping your breathing and other muscles regain their normal strength.
  • Supports a Safe Recovery from Anaesthesia: By restoring muscle function after an operation, this medication helps you recover safely and smoothly as the effects of anaesthesia wear off.
  • Reduces Unwanted Side Effects: The combination of active ingredients helps minimise unwanted effects such as a slow heart rate and excessive saliva or airway secretions that may occur during muscle relaxant reversal.
     

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Myo Pyrolate Injection 5 ml will be administered by the doctor or nurse in a healthcare setting.
  • Do not self-administer.

How Myo Pyrolate Injection 5 ml Works

Myo Pyrolate Injection 5 ml contains glycopyrolate and neostigmine, two active parts that work together to safely wake up your muscles after surgery: The first active part works by blocking the breakdown of a natural chemical messenger in your body called acetylcholine. By keeping more of this chemical active, it helps your nerves and muscles communicate again, reversing the muscle relaxation and restoring your strength. The second active part acts as a protective shield. Because the first part can cause side effects like a very slow heart rate, excess sweating, and watery saliva, this second component blocks those specific actions. This keeps your heart rate stable and your mouth comfortable while your muscles recover.
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Alcohol

Unsafe

Avoid consuming alcohol while taking Myo Pyrolate Injection 5 ml as it may cause increased dizziness.

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Pregnancy

Caution

Myo Pyrolate Injection 5 ml contains neostigmine which is a pregnancy category C drug. It may be unsafe to use during pregnancy since animal studies of Myo Pyrolate Injection 5 ml showed harmful effects on the fetus. Please consult your doctor before taking Myo Pyrolate Injection 5 ml if you are pregnant or planning to conceive.

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Breast Feeding

Caution

It is not known if Myo Pyrolate Injection 5 ml is excreted into the breast milk. Please consult your doctor before taking Myo Pyrolate Injection 5 ml if you are a breastfeeding mother.

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Driving

Unsafe

Myo Pyrolate Injection 5 ml can make you feel dizzy, eyesight becomes a week and affect your ability to drive. It is advised not to drive or operate machinery while using Myo Pyrolate Injection 5 ml if you are not mentally alert and focused.

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Liver

Caution

If u have or had a history or evidence of any liver-related diseases, please consult the doctor before taking Myo Pyrolate Injection 5 ml. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Kidney

Caution

If u have or had a history or evidence of any kidney-related diseases, please consult the doctor before taking Myo Pyrolate Injection 5 ml. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Children

Safe if prescribed

Myo Pyrolate Injection 5 ml can be given to children with caution if prescribed by the doctor, the dose depends on the child’s age and weight.

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Heart

Consult your doctor

Please inform your doctor if you have a history of heart disease before using Myo Pyrolate Injection 5 ml. Your doctor will prescribe it only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Limited information available for use of Myo Pyrolate Injection 5 ml in elderly patients. Please consult your doctor.

What if I have taken an overdose of Myo Pyrolate Injection 5 ml

An overdose is highly unlikely because this medicine is carefully measured and given by trained specialists in a hospital. However, if an overdose occurs, your healthcare team is equipped to manage it immediately. If you experience unusual weakness or breathing problems after your procedure, alert a medical professional right away.

Diet & Lifestyle Advise

  • Rest and recover: Allow your body plenty of time to rest after anaesthesia, as your muscles may still feel slightly weak or tired for a day or two.
  • Stay hydrated: Drink small sips of water once your doctor says it is safe to eat or drink, as this can help relieve any lingering dry mouth.
  • Avoid heavy physical activity: Refrain from heavy lifting, operating machinery, or strenuous exercise until your healthcare provider confirms that your muscle strength has fully returned.
  • Eat light meals first: Start with simple, easily digestible foods like broth, gelatin, or toast to prevent nausea as your digestive system wakes up after anaesthesia.
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How Soon It Starts Working

The time required for Myo Pyrolate Injection 5 ml to start to work: The effect of Myo Pyrolate Injection 5 ml begins to take action within 5 to 15 minutes of administration. The time for which the effects of Myo Pyrolate Injection 5 ml last: Myo Pyrolate Injection 5 ml effect lasts for 2 to 4 hours.

What if you forget to take Myo Pyrolate Injection 5 ml

Since Myo Pyrolate Injection 5 ml is given as a single injection by a healthcare professional during a surgical procedure, it is not possible for you to miss a dose.

Storage

•Myo Pyrolate Injection 5 ml is typically stored and managed by hospital staff. It should be kept at a controlled room temperature, ideally between 20°C and 25°C (68°F to 77°F). •Keep the medication in its original packaging to protect it from light, and do not freeze it.
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Keep Refrigerated. Do not freeze.

Drug Warnings

  • Visual check: Before injection, the medical team will inspect the solution. Do not use if the liquid is cloudy, discoloured, or contains tiny particles.
  • Monitor your heart rate: Inform your doctor immediately if you feel your heart racing or beating irregularly after the injection.
  • Avoid sudden movements: Sit up or stand up slowly after surgery to prevent dizziness or lightheadedness.
  • Tell your doctor about allergies: Always inform your anaesthesia team about any allergies you have to medications or preservatives before surgery.

Drug-Drug Interactions

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Inform your doctor about all the medicines you are using before using this, as they may interact with Myo Pyrolate Injection 5 ml and affect your treatment.

  • May increase the risk of an overly fast heart rate or dry mouth if used with other anticholinergic medications.
  • May have reduced effectiveness if combined with certain antibiotics (like aminoglycosides) or magnesium, which can interfere with muscle recovery.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No clinically significant food interactions are known with Myo Pyrolate Injection 5 ml when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[MUSCLE STIMULANTS AND CHOLINESTERASE INHIBITORS]

FAQs

Myo Pyrolate Injection 5 ml is used to reverse the effects of muscle relaxants and anaesthesia medicines used during surgery.
Myo Pyrolate Injection 5 ml contains two medicines namely: Glycopyrrolate and Neostigmine. Neostigmine increases levels of a substance known as acetylcholine by stopping an enzyme required for the breakdown of acetylcholine involved in transmission between nerve impulses and muscle movements. It is used at the end of surgery to reverse the effects of several medicines used during surgery like anesthetics and muscle relaxants. Glycopyrrolate is an anticholinergic It works by blocking the activity of a chemical messenger (acetylcholine) in the brain. It is added to avoid the unwanted effects of neostigmine like stomach acid, excess saliva production and decreased heart rate.
Myo Pyrolate Injection 5 ml should be used with caution in the medical history of asthma, breathing problems, stomach ulcers, high temperature, high blood pressure, heart attack, heart disease, overactive thyroid (hypothyroidism). Please let your doctor know if you have any other medical problems before starting Myo Pyrolate Injection 5 ml.
Do not stop taking Myo Pyrolate Injection 5 ml on your own. To treat your condition effectually please continue taking Myo Pyrolate Injection 5 ml for the prescribed period. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Myo Pyrolate Injection 5 ml.
Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose.
Keep Myo Pyrolate Injection 5 ml in a cool, dry place away from direct sunlight. Dispose of unused medicine and keep it out of sight and reach from children and pets.
This medicine is injected directly into a vein (intravenously) by a trained healthcare professional, such as an anesthesiologist, while you are in the operating room or recovery area. Talk to your doctor for more details.
Myo Pyrolate Injection 5 ml typically begins to work within a few minutes after it is injected, helping you regain muscle strength rapidly as you wake up from anaesthesia. Talk to your doctor if you feel prolonged weakness.
No, you should not drive, operate machinery, or perform any dangerous tasks for at least 24 hours after receiving this medicine and anaesthesia, as it can cause temporary drowsiness and blurred vision. Talk to your doctor about when it is safe to resume driving.
Yes, a dry mouth is a very common but temporary side effect of Myo Pyrolate Injection 5 ml. It usually resolves on its own within a few hours after surgery. Talk to your doctor if this discomfort persists.
Myo Pyrolate Injection 5 ml is only used during pregnancy if the potential benefits outweigh the risks to the baby. Your surgical team will evaluate your health needs carefully. Talk to your doctor if you are pregnant or planning a pregnancy.
Yes, Myo Pyrolate Injection 5 ml can be used in children under strict medical supervision, with the dosage carefully adjusted based on their body weight. Talk to your doctor for specific pediatric guidance.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.6599 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. Ministry of Health and Family Welfare. National Formulary of India (NFI) 2021. 6th ed. New Delhi, India: IPC; 2021. Clinical Drug Monographs: Myo Pyrolate Injection
  3. If you suffer from asthma attacks, wheezing, or difficulty in breathing
  4. If you have low or high blood pressure
  5. If you suffer from cardiac arrhythmia (irregular heartbeats) or slow heart rate

Country of origin

India

Manufacturer/Marketer address

140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.
Other Info - MYO0148
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