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compositionComposition:PEMETREXED-100MG
prescription
Prescription Medicine
info
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Mytrex 100 Inj is used to treat Non-small cell lung cancer and malignant pleural mesothelioma. It contains Pemetrexed, which treats cancer by blocking the action of substances that may help the cancer cells multiply. Do not use this medication if you are pregnant or breastfeeding. Women and men should use effective contraception during treatment with Mytrex 100 Inj and for 6 and 3 months afterwards. It is not recommended for children below 18 years.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

PEMETREXED-100MG

Manufacturer/Marketer :

Mylan Pharmaceuticals Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Mytrex 100 Inj

Mytrex 100 Inj is an injection used to treat certain types of cancers, such as non-small cell lung cancer and malignant pleural mesothelioma. It is a medical treatment designed to slow down or stop the growth of cancer cells in the body. By targeting these abnormal cells, the medicine helps manage the disease and prevent it from spreading further.

This medicine is given as an infusion into a vein on a schedule determined by your doctor, usually once every three weeks. Because it is given in a clinical setting by healthcare professionals, maintaining your scheduled appointments is vital for consistent results. Staying well-hydrated and eating balanced, small meals during your treatment cycle can support your body through therapy.

Common side effects of this treatment include fatigue, nausea, and low blood cell counts. You must contact your doctor immediately if you develop signs of an infection, such as a fever, or experience unusual bleeding and bruising. Your healthcare team will monitor your blood counts regularly to ensure it is safe for you to continue treatment.

Before you begin taking Mytrex 100 Inj, tell your doctor if you have kidney disease, as this condition can affect how your body clears the medicine. Do not take this if you have had a severe allergic reaction to this medicine or any of its ingredients. It is also important to share your complete medical history with your oncologist before your first session.

Certain medicines, such as nonsteroidal anti-inflammatory drugs (NSAIDs), can interact with Mytrex 100 Inj and increase your risk of severe side effects. Avoid alcohol and smoking during treatment, as they can place extra strain on your liver and worsen fatigue. If you are pregnant, planning to become pregnant, or breastfeeding, you should not take this medicine, and elderly patients may require closer monitoring of their kidney function.

Uses of Mytrex 100 Inj

Mytrex 100 Inj is used to treat certain types of cancers. The detailed uses of Mytrex 100 Inj are as follows:

  • Non-small cell lung cancer: Mytrex 100 Inj helps by stopping the division and growth of cancer cells in patients with advanced non-squamous non-small cell lung cancer.
  • Malignant pleural mesothelioma: Mytrex 100 Inj is used in combination with other chemotherapy drugs to treat this rare cancer of the lung lining, helping to control tumour growth.

Key Benefits

Mytrex 100 Inj helps treat certain types of cancer by slowing the growth and spread of cancer cells. With regular use as prescribed, it helps control disease progression, relieve tumour-related symptoms, and support long-term treatment outcomes.

  • Helps Control Cancer Progression: By slowing the growth or stabilising tumours, this medicine helps manage the disease and delay its progression.
  • Relieves Cancer-Related Symptoms: As tumour growth is controlled, this medicine may help reduce persistent coughing, chest pain, breathing difficulties, and other symptoms caused by cancer, improving daily comfort.
  • Supports Long-Term Disease Management: When used as maintenance therapy after initial treatment, this medicine helps delay the return of cancer, prolong disease control, and support better quality of life and overall treatment outcomes.
Side effects of Mytrex 100 Inj
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
  • Avoid contact with people who are sick.
  • Wash your hands regularly with soap and water.
  • Avoid unpasteurized dairy products.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Mytrex 100 Inj will be administered by a nurse or doctor.
  • Do not self-administer.

How Mytrex 100 Inj Works

Mytrex 100 Inj contains pemetrexed, which is a folate antimetabolite that works by disrupting the replication process of cancer cells. Cancer cells require certain natural substances, including folate, to synthesise DNA and RNA so they can grow and divide. This medicine acts as an impostor, blocking the specific enzymes that use folate to build genetic material. Without the necessary building blocks for DNA, the cancer cells are unable to replicate and eventually die. Because cancer cells divide much faster than most healthy cells, they are highly sensitive to this blockage, which helps limit the spread of the disease throughout your body.
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Alcohol

Consult your doctor

It is not known if alcohol affects Mytrex 100 Inj. Please consult your doctor.

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Pregnancy

Unsafe

Pemetrexed belongs to pregnancy category D. The use of Mytrex 100 Inj should be avoided during pregnancy as it might harm the unborn baby.

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Breast Feeding

Unsafe

Breastfeeding must be discontinued during treatment with Mytrex 100 Inj.

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Driving

Caution

Mytrex 100 Inj may cause tiredness. Caution is advised while driving or operating heavy machinery.

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Liver

Consult your doctor

If you have a history of liver disease, inform your doctor before receiving Mytrex 100 Inj.

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Kidney

Caution

Dose adjustment may be needed. If you have a history of kidney disease, inform your doctor before receiving Mytrex 100 Inj.

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Children

Unsafe

Mytrex 100 Inj is not recommended for children below 18 years as safety and effectiveness have not been established.

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Heart

Consult your doctor

Please consult your doctor if you have any heart problems before taking Mytrex 100 Inj.

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Geriatrics

Consult your doctor

Please consult a doctor before administering Mytrex 100 Inj to geriatric patients. Your doctor will prescribe Mytrex 100 Inj if the benefits outweigh the risks.

What if I have taken an overdose of Mytrex 100 Inj

An overdose is highly unlikely because a trained medical professional prepares and injects your dose. However, if you suspect an error or experience severe symptoms after your session, seek immediate medical attention.

Diet & Lifestyle Advise

  • Take your prescribed supplements: Always take your folic acid and vitamin B12 supplements exactly as directed to help protect your healthy blood cells from the medicine.
  • Stay well-hydrated: Drink plenty of water and clear fluids, especially on the days surrounding your treatment, to help support your kidney function.
  • Eat small, frequent meals: If you experience nausea or a loss of appetite, eating smaller portions five to six times a day can help maintain your nutrition.
  • Avoid infections: Wash your hands frequently, practice good personal hygiene, and avoid close contact with anyone who is currently sick.
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How Soon It Starts Working

The time required for Mytrex 100 Inj to start to work: The time required for Mytrex 100 Inj to show its action is not clinically established. The time for which the effects of Mytrex 100 Inj last: The effect of Mytrex 100 Inj lasts for 6 to 9 hours.

What if you forget to take Mytrex 100 Inj

Since this medicine is given by a healthcare professional at scheduled clinical visits, missing a dose is unlikely. If you miss an appointment, contact your clinic immediately to reschedule your infusion.

Storage

• Unopened vials of Mytrex 100 Inj dry powder should be stored at room temperature, between 20°C to 25°C (68°F to 77°F).
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Keep Refrigerated. Do not freeze.

Drug Warnings

  • Check the solution: If you observe your treatment being prepared, ensure the liquid is clear, colourless to light yellow, and free of visible particles before it is injected.
  • Monitor your temperature: Keep a reliable digital thermometer at home and check your temperature immediately if you feel warm, cold, or unwell.
  • Avoid certain pain relievers: Do not take ibuprofen, naproxen, or other NSAIDs for a few days before and after your infusion without consulting your doctor first, as they can increase the medicine's toxicity.
  • Protect your skin: Use gentle, fragrance-free moisturisers and wear sunscreen when outdoors, as your skin may become highly sensitive during treatment.

Drug-Drug Interactions

verifiedApollotooltip

  • Nonsteroidal anti-inflammatory drugs (NSAIDs): Medicines like ibuprofen or naproxen can slow down the removal of Mytrex 100 Inj from your body, increasing the risk of severe side effects.
  • Kidney-damaging medicines: Other medications that can strain the kidneys may increase the toxicity of Mytrex 100 Inj if used at the same time.
PemetrexedEtanercept
Severe
PemetrexedMeloxicam
Severe

Drug-Drug Interactions

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PemetrexedEtanercept
Severe
How does the drug interact with Mytrex 100 Inj:
When Etanercept is used with Mytrex 100 Inj, the likelihood or severity of infection may increase.

How to manage the interaction:
Although taking Mytrex 100 Inj and Etanercept together can cause an interaction, it can be taken if a doctor has suggested it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
PemetrexedMeloxicam
Severe
How does the drug interact with Mytrex 100 Inj:
Co-administration of Meloxicam and Mytrex 100 Inj together may increase the levels of Mytrex 100 Inj in the blood.

How to manage the interaction:
Co-administration of Meloxicam with Mytrex 100 Inj can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice symptoms like fever, chills, flu-like symptoms, mouth sores, severe diarrhea, or any injuries, call a doctor right away. Do not discontinue any medications without consulting a doctor.
PemetrexedCladribine
Severe
How does the drug interact with Mytrex 100 Inj:
Taking Cladribine with Mytrex 100 Inj can increase the risk of developing serious infections.

How to manage the interaction:
Although taking Cladribine and Mytrex 100 Inj together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
PemetrexedClozapine
Severe
How does the drug interact with Mytrex 100 Inj:
Combining Mytrex 100 Inj with Clozapine can increase the risk of infection.

How to manage the interaction:
Co-administration of Mytrex 100 Inj with Clozapine can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
PemetrexedTofacitinib
Severe
How does the drug interact with Mytrex 100 Inj:
Taking Tofacitinib with Mytrex 100 Inj may increase the risk of infection.

How to manage the interaction:
Although there is a possible interaction between Mytrex 100 Inj and Tofacitinib, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
PemetrexedBaricitinib
Severe
How does the drug interact with Mytrex 100 Inj:
Coadministration of Mytrex 100 Inj with Baricitinib can increase the risk of developing serious infections.

How to manage the interaction:
Although taking Mytrex 100 Inj and Baricitinib together can cause an interaction, it can be taken if your doctor has suggested it. However, consult a doctor if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate. Do not stop using any medications without a doctor's advice.
PemetrexedInfliximab
Severe
How does the drug interact with Mytrex 100 Inj:
When Mytrex 100 Inj is taken with Infliximab, it can enhance the metabolism of Mytrex 100 Inj. This can reduce the treatment outcome and can increase the risk or severity of developing serious infections.

How to manage the interaction:
Taking Mytrex 100 Inj with Infliximab together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PemetrexedThalidomide
Severe
How does the drug interact with Mytrex 100 Inj:
Taking thalidomide together with Mytrex 100 Inj may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Mytrex 100 Inj together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Mytrex 100 Inj when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[CHEMOTHERAPY]

FAQs

Your doctor may prescribe folic acid and vitamin B12 before and during treatment with Mytrex 100 Inj to help protect healthy cells and reduce the risk and severity of certain side effects, particularly blood-related and gastrointestinal side effects. Take these supplements exactly as directed by your doctor.
Hair thinning or mild hair loss can occur during treatment with Mytrex 100 Inj, although complete hair loss is less common than with many other chemotherapy medicines. Speak with your doctor if you are concerned or if hair loss becomes troublesome.
This medicine can cause severe fatigue, dizziness, or weakness. Avoid driving or operating machinery until you know how the treatment affects you. Talk to your doctor.
No, this medicine can cause severe harm to an unborn baby. Both men and women should use highly effective birth control during treatment and for several months afterwards. Talk to your doctor.
The medicine is typically given once every three weeks, but your oncologist will determine the exact schedule based on your response to the therapy. Talk to your doctor.
It is best to avoid alcohol, as it can worsen liver strain, dehydration, and fatigue associated with your treatment. Talk to your doctor.
You should avoid live vaccines because your immune system may be weakened by the treatment, which could make the vaccine unsafe. Talk to your doctor.
Skin rashes are a known side effect. Your doctor may prescribe steroid tablets to take before your injection to prevent this, but you should report any new skin changes immediately. Talk to your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Mylan Pharmaceuticals Private Limited , Commercial Operations , Prestige Tech Park,Platina-3, 7th to 12th floor, Prestige Tech Park, Kadubesanahalli, Bangalore -560103
Other Info - MYT0041
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