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NAC PLUS TABLET, Pack of 10 TABLETS
NAC PLUS TABLET, Pack of 10 TABLETS
NAC PLUS TABLET, Pack of 10 TABLETS
NAC PLUS TABLET, Pack of 10 TABLETS
NAC PLUS TABLET, Pack of 10 TABLETS
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
NAC PLUS TABLET is used to relieve pain associated with osteoarthritis, sprain, strain, rheumatoid arthritis and ankylosing spondylitis. It contains Diclofenac and Acetaminophen which work by inhibiting chemical messengers that cause pain and inflammation. This medicine may sometimes cause side effects such as stomach upset, dizziness, light-headedness, malaise, nausea, vomiting and rash. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

ACETAMINOPHEN-500MG + DICLOFENAC-50MG

Manufacturer/Marketer :

Systopic Laboratories Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About NAC PLUS TABLET

NAC PLUS TABLET belongs to a class of medications known as a non-steroidal anti-inflammatory drug (NSAID) or pain killer. NAC PLUS TABLET is primarily indicated for relieving pain associated with bones and muscles like osteoarthritis (joints pain), sprains and strains of muscles, rheumatoid arthritis (pain, swelling, and stiffness of joints) and ankylosing spondylitis (inflammation of the spine). This medicine also provides relief in pain associated with back pain, toothache,  rheumatoid arthritis, painful menses, mild migraine, etc. Pain is an uncomfortable feeling in the body that can range from annoying to severe.

NAC PLUS TABLET contains Diclofenac (analgesic) and Acetaminophen (fever reducer/mild analgesic) effective against painful musculoskeletal pain, joint pain, and skeletal muscle spasms. Diclofenac works by blocking the action of a chemical messenger known as cyclo-oxygenase (COX) which causes pain and swelling at the injured or damaged tissue site. On the other hand, Acetaminophen acts as a mild analgesic (mild pain reducer) and antipyretic (fever reducer), which enhances the pain relief action of Diclofenac. Both medicines in combination work well to provide relief pain in different conditions.

Take NAC PLUS TABLET as prescribed by your doctor. You are advised to take NAC PLUS TABLET for as long as your doctor has prescribed it for you depending on your medical condition. Like all medicines, NAC PLUS TABLET may cause common side effects like stomach upset, dizziness, light-headedness, malaise, nausea, vomiting and liver dysfunction (hepatitis), pruritis (itchy skin), rash, although not everybody gets them. Stop taking this medicine if you experience symptoms like the tightness of the chest, breathing difficulties, fever, skin rashes, increased heart rate and or in case of any signs of hypersensitivity.

Do not take NAC PLUS TABLET if you are allergic to painkillers like aspirin, acetaminophen, naproxen or diclofenac. It is not recommended for use in children less than 14 years of age, people with liver disease, heart disease or gastric ulcers/bleeding problems. NAC PLUS TABLET may be associated with a small increase in the risk of heart attack (myocardial infarction). Pregnant women should not take this medicine during their last trimester of pregnancy. NAC PLUS TABLET is excreted in the breast milk so the nursing mother should contact the doctor before its usage. Avoid consumption of alcohol as it may damage your liver and cause even more side effects from taking this drug.

Uses of NAC PLUS TABLET

Treatment of Musculoskeletal pain, Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis, Rheumatoid arthritis, Painful menses, Mild migraine, etc.

Directions for Use

• NAC PLUS TABLET can be taken with food or as advised by your doctor.• Follow your doctor's instructions on the dosage and timing of this medication.• Swallow NAC PLUS TABLET as a whole with a glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

NAC PLUS TABLET is a combination medicine used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle pain, tooth pain, bone and joint pain, headache, swelling, period pain, ear pain, migraine, fever,  sore throat, nose pain, etc.  By reducing the pain, NAC PLUS TABLET helps you to do normal daily activities of the day. Diclofenac present in NAC PLUS TABLET works by reducing the chemical messenger that is responsible for pain and inflammation in the body. While Acetaminophen works by blocking chemical messenger that sends pain signals to the brain. This medicine also reduces fever by regulating body temperature. Both medicines in combination increase the pain threshold and blood flow across the skin and provide relief in various painful conditions.

How NAC PLUS TABLET Works

NAC PLUS TABLET contains Diclofenac (analgesic) and Acetaminophen (fever reducer/mild analgesic) effective against painful musculoskeletal pain, joint pain, and skeletal muscle spasms. Diclofenac works by blocking the action of a chemical messenger known as cyclo-oxygenase (COX) which causes pain and swelling at the injured or damaged tissue site. On the other hand, Acetaminophen acts as a mild analgesic (mild pain reducer) and antipyretic (fever reducer), which enhances the pain relief action of Diclofenac. Both medicines in combination work well to provide relief pain in different conditions.

Storage

Keep NAC PLUS TABLET out of the sight and reach of children.

What if I have taken an overdose of NAC PLUS TABLET

Take NAC PLUS TABLET only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include nausea, vomiting, drowsiness, lethargy, epigastric pain, gastrointestinal bleeding, and liver toxicity. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take NAC PLUS TABLET if you have/had severe heart problems, stomach ulcer or perforation, bleeding problems such as bleeding from the stomach, intestine or brain, have undergone any heart bypass surgery, have had any heart attack, blood circulation problems or inflammation of intestines.  Patients with asthma, prolonged bleeding time, wheezing (whistling sound during breath) and blocked airways (bronchospasm) should avoid using NAC PLUS TABLET. Consult your doctor if your symptoms of pain, inflammation and fever do not disappear even after ten days. If you are using topical form NAC PLUS TABLET you should avoid direct exposure to the sunlight as sunburn or photosensitivity might occur. Keep your doctor informed about your health condition and medicines to rule out any side-effects. Avoid simultaneous consumption of other painkillers or cough and cold medicines with this NAC PLUS TABLET as it may lead to overdose.  Stop taking NAC PLUS TABLET and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach such as blood in stools. Do not take any other NSAID's for pain relief along with NAC PLUS TABLET unless prescribed. 

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
DiclofenacLomitapide
Severe

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
How does the drug interact with Nac Plus Tablet:
Co-administration of Nac Plus Tablet with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Nac Plus Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
DiclofenacLomitapide
Severe
How does the drug interact with Nac Plus Tablet:
Taking Nac Plus Tablet with Lomitapide will have an additive effect and may cause liver problems.

How to manage the interaction:
There may be a possible interaction between Nac Plus Tablet and Lomitapide, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you have fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark colored urine, light colored stools, and/or yellowing of the skin or eyes. Do not stop using any medications without a doctor's advice.
DiclofenacKetoconazole
Severe
How does the drug interact with Nac Plus Tablet:
Coadministration of Nac Plus Tablet with Ketoconazole may increase the risk of liver problems.

How to manage the interaction:
There may be a possible interaction between Nac Plus Tablet and Ketoconazole, but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you have fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark colored urine, light colored stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
DiclofenacSulindac
Severe
How does the drug interact with Nac Plus Tablet:
Co-administration of Nac Plus Tablet and sulindac can increase the risk of side effects.

How to manage the interaction:
Although there is a interaction between Nac Plus Tablet and sulindac, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacPiroxicam
Severe
How does the drug interact with Nac Plus Tablet:
Taking Nac Plus Tablet and piroxicam can increase the risk of side effects such as ulcers, inflammation (redness, swelling), bleeding.

How to manage the interaction:
Co-administration of Nac Plus Tablet and Piroxicam can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacTolmetin
Severe
How does the drug interact with Nac Plus Tablet:
Taking Nac Plus Tablet with Tolmetin may increase the risk of side effects.

How to manage the interaction:
There may be a possible interaction between Nac Plus Tablet and Tolmetin but can be taken if prescribed by doctor. However, consult your doctor immediately if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medications without consulting a doctor.
DiclofenacIbrutinib
Severe
How does the drug interact with Nac Plus Tablet:
Taking Nac Plus Tablet with Ibrutinib can increase the risk of bleeding tendencies.

How to manage the interaction:
There may be a possible interaction between Nac Plus Tablet and Ibrutinib, but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you experience any unusual bleeding, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, or severe headaches. Do not discontinue any medications without consulting a doctor.
DiclofenacVorapaxar
Severe
How does the drug interact with Nac Plus Tablet:
Taking Nac Plus Tablet with Vorapaxar can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possible interaction between Nac Plus Tablet and Vorapaxar, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headaches. Do not discontinue any medications without consulting your doctor.
DiclofenacMethotrexate
Severe
How does the drug interact with Nac Plus Tablet:
Co-administration of methotrexate with Nac Plus Tablet can increase the levels and effects of methotrexate. This can lead to increased risk of side effects.

How to manage the interaction:
Although there is a possible interaction between methotrexate and Nac Plus Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as mouth sores or ulcers, nausea, vomiting, diarrhea, rash, loss of hunger, joint pain or swelling, yellowing of the skin or eyes, dark urine, shortness of breath, a dry cough, paleness, dizziness or fainting, unusual bruising or bleeding, fits, infection, fever, chills, body aches, sore throat or muscle weakness, consult a doctor immediately. Do not stop using medications without a doctor's advice.
DiclofenacDalteparin
Severe
How does the drug interact with Nac Plus Tablet:
Co-administration use of Nac Plus Tablet with Dalteparin may increase the risk of bleeding complications.

How to manage the interaction:
Although taking Dalteparin with Nac Plus Tablet may possibly lead to an interaction, they can be taken if a doctor prescribes it. Consult a doctor if you have any symptoms including dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness. Without consulting a doctor, never stop taking any medication.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes, instead, wear loose garments.
  • Rest well, get plenty of sleep.
  • To avoid developing pressure sores, change your position at least every two hours.
  • Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20 minutes.
  • Stay hydrated, drink plenty of water.

Habit Forming

No

Therapeutic Class

ANALGESICS
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Alcohol

Unsafe

Avoid consumption of alcohol while taking NAC PLUS TABLET as it may increase drowsiness. It can also increase the risk of stomach bleeding.

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Pregnancy

Caution

Avoid taking NAC PLUS TABLET if you are pregnant unless prescribed by a doctor. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking NAC PLUS TABLET, your doctor will decide whether NAC PLUS TABLET can be taken by breastfeeding mothers or not.

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Driving

Caution

NAC PLUS TABLET may affect driving ability as it causes headaches, blurred vision, dizziness or drowsiness so do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

NAC PLUS TABLET is not recommended for children below 12 years of age without the doctor's consent. For children above 12 years, the dose needs to be adjusted and recommended by a child specialist only.

Have a query?

FAQs

NAC PLUS TABLET is used to relieve pain in conditions like osteoarthritis, sprains and strains of muscles, rheumatoid arthritis, ankylosing spondylitis, back pain, toothache, painful menses, and mild migraine.

NAC PLUS TABLET should not be taken as a long term medication as it may lead to stomach ulcers/bleeding and kidney problems. For best results of NAC PLUS TABLET, take it in doses and duration mentioned by your doctor.

NAC PLUS TABLET is not indicated for stomach pain. Also, If you have stomach pain post-ingestion it may be a sign of stomach ulcer or gastric bleeding. Do not take NAC PLUS TABLET in this condition. It is better to inform your doctor in case of stomach pain.

It is advised not to take NAC PLUS TABLET until prescribed by your doctor.

Yes, NAC PLUS TABLET is a short term medication and if you feel better you can stop taking NAC PLUS TABLET, but only after consulting your doctor.

NAC PLUS TABLET is a combination of two drugs, namely: Diclofenac, and Acetaminophen. Diclofenac and Acetaminophen work by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandin (PG). By blocking the COX enzyme's effect, lesser PGs are produced, which reduces mild to moderate pain, fever and inflammation at the injured or damaged site.

NAC PLUS TABLET is used to reduce and relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. Arthritis is the tenderness and swelling in the joints.

NAC PLUS TABLET should not be taken for longer durations unless prescribed by the doctor. If NAC PLUS TABLET has been prescribed for longer durations, regular monitoring of kidney function, liver function and blood count is advised, particularly in elderly patients.

Diarrhea might be a side-effect of NAC PLUS TABLET. Drink enough fluids and eat fiber rich food if you experience diarrhea. If you find blood in stools (tarry stools) or if you experience excess diarrhea consult your doctor. Do not take anti-diarrheal medicine on your own.

No, NAC PLUS TABLET is not used to treat migraine, it is used to decrease pain caused by mild migraine.

Before taking NAC PLUS TABLET, consult your doctor and share your medical history. Follow the recommended dosage and be mindful of potential interactions with other medications or health conditions. Be cautious if you're pregnant, breastfeeding, or have specific health concerns. Always prioritize your safety and well-being.

NAC PLUS TABLET should only be used in children with a doctor's guidance. It is generally not recommended for children under 12 years of age due to potential risks, such as kidney damage, stomach pain, and bleeding. Always consult a healthcare provider before giving NAC PLUS TABLET to children (over 12 years old), as the dose may need to be tailored based on the child's specific needs.

NAC PLUS TABLET is composed of diclofenac (an anti-inflammatory) and acetaminophen (a fever reducer/mild analgesic), which are primarily used to relieve pain and inflammation associated with bones and muscles.

NAC PLUS TABLET is generally safe when used as directed by your doctor, especially for short-term relief of pain associated with bones and muscles. However, it should be used with caution, as prolonged use or high doses may lead to liver damage, stomach ulcers, and bleeding. Please consult your doctor if you have concerns about the safety of NAC PLUS TABLET or need personalized advice.

NAC PLUS TABLET may cause mild side effects, such as nausea and vomiting, in some individuals. It contains a nonsteroidal anti-inflammatory drug (Diclofenac), which can irritate the stomach lining, leading to nausea or vomiting. To manage these side effects, take NAC PLUS TABLET with food or a full glass of water. If the nausea or vomiting is severe, please consult a doctor.

NAC PLUS TABLET may cause dizziness as a potential side effect in some individuals. Avoid driving or operating machinery if you feel dizzy after taking NAC PLUS TABLET. Usually, these effects fade away with time. If the dizziness persists or becomes severe, please consult your doctor, as they may adjust the dosage or recommend alternative treatments.

NAC PLUS TABLET may damage the kidneys if taken in high doses or for a prolonged period, especially if you have pre-existing kidney problems. Acetaminophen can cause liver damage if overused, while diclofenac (a nonsteroidal anti-inflammatory drug) can impair kidney function. Please consult your doctor before using NAC PLUS TABLET; they may adjust the dosage if necessary.

NAC PLUS TABLET has specific contraindications, including allergies to any ingredients or other NSAIDs, active stomach ulcers or bleeding, severe liver or kidney disease, severe heart conditions (history of heart attack or stroke), asthma, and recent heart bypass surgery. However, this is not an exhaustive list. It's essential to consult your doctor for full information and determine if this medication suits you. Your doctor will assess your individual circumstances and advise whether this medication is appropriate for your needs, ensuring safe and effective treatment.

Yes, NAC PLUS TABLET and Vitamin B-complex can generally be taken together, as no known major interactions exist between them. However, it is essential to consult a healthcare provider before taking NAC PLUS TABLET with supplements or other medications to ensure safety and avoid potential interactions.

No, taking a dose higher than the recommended dose of NAC PLUS TABLET is not safe. High doses of NAC PLUS TABLET may lead to liver damage (due to acetaminophen) and increase the risk of stomach bleeding and kidney damage (due to diclofenac). Always follow the dosing instructions and consult a doctor if you are unsure.

NAC PLUS TABLET should be stored in a cool and dry place, away from direct sunlight and moisture. Keep it out of reach of children.

If you have a peptic ulcer, you should avoid taking NAC PLUS TABLET, as it may irritate the stomach lining and worsen the ulcer (especially because of diclofenac, a nonsteroidal anti-inflammatory drug [NSAID]). Please consult your healthcare provider before taking NAC PLUS TABLET to ensure it is appropriate for your condition.

NAC PLUS TABLET may cause common side effects such as stomach upset, dizziness, light-headedness, malaise, nausea, vomiting, liver dysfunction (hepatitis), pruritus (itchy skin), and rash. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Avoid taking NAC PLUS TABLET during pregnancy unless prescribed by a doctor. In particular, diclofenac (one of its ingredients) is not recommended during the last trimester, as it may harm the baby. Please consult your doctor if you have any concerns regarding this. Your doctor will prescribe it only if the benefits outweigh the risks.

It is generally not recommended to drink alcohol while taking NAC PLUS TABLET. Both alcohol and NAC PLUS TABLET can strain the liver and increase the risk of liver damage or stomach bleeding. Drinking alcohol may also increase drowsiness, so do not drive or operate machinery unless you are fully alert. Always consult your doctor for personalized advice.

Country of origin

India

Manufacturer/Marketer address

Systopic Laboratories Pvt. Ltd., 101, Pragati Chambers, Commercial Complex, Ranjit Nagar, New Delhi-110008
Other Info - NAC0003

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:48 AM IST

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Reference

  1. https://www.mims.com/india/drug/info/diclofenac%20+%20paracetamol?type=full&mtype=generic
  2. https://www.torquepharma.com/product-detail.php?id=122&catid=7
  3. https://www.nhs.uk/medicines/diclofenac/

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