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compositionComposition:DICLOFENAC-150MG
prescription
Prescription Medicine
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Nac Sr 150mg Tablet is used to relieve pain and inflammation associated with migraine, muscle pain, dental pain, rheumatoid arthritis, ankylosing spondylitis, osteoarthritis, gout, strain, and sprain. It contains Diclofenac, which works by blocking the effect of an enzyme called cyclo-oxygenase (COX) that produces prostaglandins responsible for pain and inflammation. Thereby, it provides relief from pain and inflammation. It may cause certain side effects such as stomach pain, heartburn, nausea, vomiting, diarrhoea, indigestion, loss of appetite, headache, and dizziness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

DICLOFENAC-150MG

Manufacturer/Marketer :

Systopic Laboratories Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Nac Sr 150mg Tablet

Nac Sr 150mg Tablet is a tablet primarily used to reduce pain, swelling, and joint stiffness caused by various inflammatory conditions. It helps manage symptoms of arthritis, muscle aches, and other painful bone or joint issues in adults. This medicine works by stopping the body from producing certain natural chemicals that cause inflammation.

To get the best results, you should take Nac Sr 150mg Tablet exactly as your doctor prescribes, often at regular intervals to maintain steady levels in your body. It is generally recommended to take this tablet with a glass of water, and taking it with food or milk can help protect your stomach from irritation. Alongside taking this medicine, incorporating gentle low-impact exercises and maintaining a healthy weight can significantly improve your joint mobility.

While taking Nac Sr 150mg Tablet , you may experience mild side effects like a mild upset stomach, nausea, or dizziness. However, you must contact your doctor immediately if you experience serious symptoms, such as severe stomach pain, black or tarry stools, or sudden shortness of breath.

Before starting Nac Sr 150mg Tablet , tell your doctor if you have a history of high blood pressure, heart problems, or kidney issues. Do not take this if you have an active stomach ulcer, severe heart failure, or if you have ever had an allergic reaction or asthma attack triggered by aspirin or other pain relievers.

This medicine can interact with blood thinners, blood pressure medications, and alcohol, which can increase your risk of stomach bleeding or kidney problems. If you are pregnant, planning a pregnancy, breastfeeding, or are an older adult, consult your doctor or pharmacist before taking Nac Sr 150mg Tablet . NSAID medicines such as Nac Sr 150mg Tablet may pose risks during pregnancy, particularly after 20 weeks of gestation. 

Uses of Nac Sr 150mg Tablet

Nac Sr 150mg Tablet is used to treat joint issues. The detailed uses of Nac Sr 150mg Tablet are as follows:

  • Osteoarthritis: Nac Sr 150mg Tablet relieves joint pain, swelling, and stiffness, making daily movements easier.
  • Rheumatoid arthritis: It targets chronic joint inflammation and helps reduce swelling and morning stiffness.
  • Ankylosing spondylitis: It helps manage painful inflammation in the spine, improving flexibility and comfort.
  • Acute muscle pain and gout flare-ups: It quickly reduces severe, short-term pain and inflammation in muscles and joints.
     

Key Benefits

Nac Sr 150mg Tablet provides targeted relief that helps you return to your normal daily activities. It delivers several key benefits:

  • Effective Pain Relief: It targets the source of discomfort, helping to significantly lower pain levels so you can go about your day comfortably.
  • Reduced Joint Swelling and Stiffness: By lowering inflammation, this medicine helps restore flexibility to your joints, allowing for smoother, pain-free movement and faster recovery after physical strain.
  • Improved Daily Functioning: Relief from chronic joint pain means you can participate more easily in physical therapy, work, and recreational activities, enhancing your overall quality of life.
     
Side effects of Nac Sr 150mg Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Consult a doctor for a proper diagnosis, as elevated liver enzymes or high protein levels may indicate liver disease or other health issues.
  • Your doctor may adjust the medication dosage or switch to a different medication if the condition is caused by it.
  • Limit or avoid alcohol to reduce stress on the liver.
  • To promote liver health, eat a well-balanced diet rich in fruits and vegetables, whole grains, and lean proteins.
  • Exercise regularly, like walking or jogging, to support liver health.
  • Regular blood tests are necessary to check enzyme levels and progress.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.

Directions for Use

To get the full benefit of Nac Sr 150mg Tablet and minimise side effects, follow these simple guidelines:

  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can destroy its protective coating and increase the risk of stomach irritation.
  • Take the tablet during or immediately after a meal to help prevent stomach upset.
  • Always take Nac Sr 150mg Tablet exactly as prescribed by your doctor. Do not change your dose or stop taking it without consulting them first.
     

How Nac Sr 150mg Tablet Works

Nac Sr 150mg Tablet contains diclofenac and belongs to a class of medicines called nonsteroidal anti-inflammatory drugs (NSAIDs). When your body experiences injury or joint damage, it produces natural chemicals called prostaglandins, which trigger pain, fever, and swelling. This medicine works by blocking the specific enzymes (known as COX enzymes) responsible for making these prostaglandins. By lowering the production of these chemicals in your body, Nac Sr 150mg Tablet effectively reduces both the painful sensations and the physical swelling in your joints and muscles.
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Nac Sr 150mg Tablet to avoid unpleasant side effects.

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Pregnancy

Consult your doctor

Nac Sr 150mg Tablet is not recommended during pregnancy. Please consult your doctor. Your doctor will prescribe an alternative medicine after overweighing the benefits over the risks.

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Breast Feeding

Caution

There is not enough evidence to establish the safety of Nac Sr 150mg Tablet in nursing mothers. So, it is advisable to take Nac Sr 150mg Tablet only if prescribed by your doctor.

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Driving

Unsafe

Nac Sr 150mg Tablet may cause dizziness. So avoid driving or drive only if you are alert.

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Liver

Consult your doctor

If u have or had a history of any liver-related diseases, please consult the doctor before taking Nac Sr 150mg Tablet .

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Kidney

Consult your doctor

If you have or had a history of kidney-related diseases, please consult a doctor before taking Nac Sr 150mg Tablet .

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Children

Unsafe

Nac Sr 150mg Tablet not recommended for children under 12 years of age.

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Heart

Consult your doctor

Nac Sr 150mg Tablet should be used with caution in heart patients, as it can cause an increase in the risk of side effects.

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Geriatrics

Caution

Nac Sr 150mg Tablet should be used with caution in elderly patients. Please consult your doctor before use.

What if I have taken an overdose of Nac Sr 150mg Tablet

Do not take more than the prescribed dose of Nac Sr 150mg Tablet as it may cause overdose. The symptoms of overdose include stomach pain, nausea, vomiting, drowsiness, bloody/black/tarry stools, slow/shallow/irregular breathing, loss of consciousness and vomiting a substance that is bloody or looks like coffee grounds. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Stay hydrated: Drink plenty of water throughout the day to help your kidneys filter the medication safely and efficiently.
  • Protect your stomach: Avoid consuming spicy or highly acidic foods if you experience stomach sensitivity while taking this medicine.
  • Maintain low-impact activity: Engage in gentle exercises like swimming, walking, or cycling to keep your joints flexible without putting excess stress on them.
  • Apply warm or cold compresses: Use ice packs to reduce acute joint swelling or warm compresses to soothe stiff muscles alongside your medication.
  • Watch your salt intake: If you have high blood pressure, limit your sodium intake, as NSAIDs can sometimes cause your body to retain fluids.
     
health query

Have a query?

How Soon It Starts Working

  • The time required for Nac Sr 150mg Tablet to start to work: Nac Sr 150mg Tablet ideally shows its action within 10 to 30 minutes after administration.
  • The time for which the effects of Nac Sr 150mg Tablet last: The effect of Nac Sr 150mg Tablet lasts 8 hours.

What if you forget to take Nac Sr 150mg Tablet

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and take the next dose at the scheduled time. Do not take a double dose.

Storage

Store Nac Sr 150mg Tablet tablets at controlled room temperature, ideally between 20°C and 25°C (68°F to 77°F). Keep the tablets in their original packaging to protect them from moisture and direct light.

Drug Warnings

  • Always check the tablet before taking it; do not take any tablets that are cracked, chipped, or showing signs of dampness.
  • Take Nac Sr 150mg Tablet with food, milk, or an antacid if it causes mild stomach discomfort.
  • Avoid taking this medicine with other over-the-counter pain relievers (like ibuprofen or naproxen) to prevent serious stomach irritation or kidney strain.
  • Monitor your blood pressure regularly while using this medicine, as it can sometimes cause a slight increase.
  • Limit or avoid alcohol consumption while taking Nac Sr 150mg Tablet , as the combination significantly increases your risk of stomach ulcers or bleeding.
  • Use the lowest effective dose for the shortest duration needed. Long-term or high-dose use of NSAIDs such as Nac Sr 150mg Tablet may increase the risk of serious cardiovascular events, including heart attack and stroke. 
     

Drug-Drug Interactions

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Drug-Drug Interactions

Inform your doctor if you are taking any of the following medicines, as they may interact.

  • Blood thinners (like warfarin): Taking these together can greatly increase the risk of serious stomach bleeding.
  • Other NSAIDs (like aspirin or ibuprofen): Combining these increases the likelihood of stomach ulcers and kidney damage.
  • Blood pressure medications (like ACE inhibitors or diuretics): Nac Sr 150mg Tablet may decrease the effectiveness of these medicines and increase the risk of kidney strain.

 

Drug-Food Interactions

  • Alcohol: Consuming alcohol while taking this medicine increases your risk of developing stomach bleeding or ulcers.

 

Drug-Disease Interactions

Inform your doctor if you have a history of the following conditions before taking Nac Sr 150mg Tablet , as it may worsen your condition or cause complications.

  • Stomach Ulcers or Bleeding: This medication can worsen active stomach ulcers or increase the risk of recurrent gastrointestinal bleedings.
  • Kidney or Liver Disease: Nac Sr 150mg Tablet can put extra strain on these organs, potentially worsening their function.
  • Asthma: Some people with asthma may experience breathing difficulties or allergic attacks when taking this class of medication.
  • Heart Disease or High Blood Pressure: This medicine may cause fluid retention, worsen blood pressure control, and increase the risk of serious cardiovascular events such as heart attack or stroke, particularly with prolonged use or higher doses. 
     
DiclofenacMeloxicam
Critical
DiclofenacBromfenac
Severe

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
How does the drug interact with Nac Sr 150mg Tablet:
Co-administration of Nac Sr 150mg Tablet with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Nac Sr 150mg Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
DiclofenacBromfenac
Severe
How does the drug interact with Nac Sr 150mg Tablet:
Taking Nac Sr 150mg Tablet with bromfenac will have an additive effect and may increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
There may be possible interaction between Nac Sr 150mg Tablet and bromfenac but you can take it if prescribed by a doctor. Consult your doctor if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness. Do not stop using any medications without first talking to your doctor.
DiclofenacWarfarin
Severe
How does the drug interact with Nac Sr 150mg Tablet:
Taking Nac Sr 150mg Tablet with warfarin may, increase the risk of bleeding.

How to manage the interaction:
There may be a possible interaction between Nac Sr 150mg Tablet and Warfarin, but they can be taken together if a doctor has prescribed them. However, consult your doctor immediately if you experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor. Do not discontinue any medications without consulting a doctor.
DiclofenacValdecoxib
Severe
How does the drug interact with Nac Sr 150mg Tablet:
Taking Valdecoxib with Nac Sr 150mg Tablet may increase risk of side effects.

How to manage the interaction:
There may be a possible interaction between Nac Sr 150mg Tablet and Valdecoxib but can be taken if prescribed by doctor. However, consult your doctor immediately if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medications without consulting a doctor.
DiclofenacTenofovir alafenamide
Severe
How does the drug interact with Nac Sr 150mg Tablet:
Co-administration of Nac Sr 150mg Tablet and tenofovir alafenamide may cause kidney problems.

How to manage the interaction:
There may be a possible interaction between Nac Sr 150mg Tablet and Tenofovir alafenamide but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms such as such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without talking to your doctor.
DiclofenacIbuprofen
Severe
How does the drug interact with Nac Sr 150mg Tablet:
Taking Nac Sr 150mg Tablet and ibuprofen can increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Co-administration of Nac Sr 150mg Tablet and Ibuprofen can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacLeflunomide
Severe
How does the drug interact with Nac Sr 150mg Tablet:
Co administration of Nac Sr 150mg Tablet with Leflunomide may result in liver problems.

How to manage the interaction:
Co-administration of Nac Sr 150mg Tablet and Leflunomide can lead to an interaction; it can be taken if advised by your doctor. However, if you have a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, or yellowing of the skin or eyes. Do not stop using any medication without consulting your doctor.
DiclofenacMethotrexate
Severe
How does the drug interact with Nac Sr 150mg Tablet:
Co-administration of methotrexate with Nac Sr 150mg Tablet can increase the levels and effects of methotrexate. This can lead to increased risk of side effects.

How to manage the interaction:
Although there is a possible interaction between methotrexate and Nac Sr 150mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as mouth sores or ulcers, nausea, vomiting, diarrhea, rash, loss of hunger, joint pain or swelling, yellowing of the skin or eyes, dark urine, shortness of breath, a dry cough, paleness, dizziness or fainting, unusual bruising or bleeding, fits, infection, fever, chills, body aches, sore throat or muscle weakness, consult a doctor immediately. Do not stop using medications without a doctor's advice.
DiclofenacAcalabrutinib
Severe
How does the drug interact with Nac Sr 150mg Tablet:
Taking acalabrutinib together with Nac Sr 150mg Tablet may increase the risk of bleeding.

How to manage the interaction:
Co-administration of Nac Sr 150mg Tablet and Acalabrutinib can lead to an interaction; it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacDeferasirox
Severe
How does the drug interact with Nac Sr 150mg Tablet:
Co-administration of Nac Sr 150mg Tablet and deferasirox may increase your risk of developing stomach bleeding.

How to manage the interaction:
There may be a possible interaction between Nac Sr 150mg Tablet and deferasirox but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms such as severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, increased or decreased urination, fluid retention, swelling, shortness of breath, muscle cramps, weakness, confusion, and irregular heart rhythm. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANALGESICS]

FAQs

Nac Sr 150mg Tablet is used to relieve pain and inflammation associated with migraine, muscle pain, dental pain, rheumatoid arthritis, ankylosing spondylitis, osteoarthritis, gout, strain, and sprain.
Nac Sr 150mg Tablet works by blocking the effect of an enzyme called cyclo-oxygenase (COX) that produces prostaglandins responsible for the sense of pain and inflammation. Thus, it provides relief from pain and inflammation.
Nac Sr 150mg Tablet can be stopped if it is prescribed for short-term pain relief. If it has been prescribed for long-term usage, it is advised to continue as advised by your doctor.
Nac Sr 150mg Tablet may cause dizziness in some patients. Drive only if you are alert after taking Nac Sr 150mg Tablet and omit driving if you feel dizzy.
No, Nac Sr 150mg Tablet is not indicated for stomach pain. If you have symptoms of stomach pain, contact your doctor.
You may begin to feel pain relief within a few hours of taking your first dose. However, for chronic conditions like arthritis, it may take a couple of weeks of consistent use to experience the full anti-inflammatory benefits. Talk to your doctor if your symptoms do not improve.
It is best to avoid or strictly limit alcohol while taking Nac Sr 150mg Tablet . Alcohol increases the risk of stomach irritation, bleeding, and ulcers when combined with this type of pain reliever. Talk to your doctor for personalised advice.
You should avoid taking Nac Sr 150mg Tablet during pregnancy unless specifically advised by your doctor. From around 20 weeks of pregnancy onward, NSAIDs may affect the baby's kidney function and reduce amniotic fluid levels. From around 30 weeks onward (the third trimester), Nac Sr 150mg Tablet should generally be avoided because it may cause premature closure of the fetal ductus arteriosus and other serious complications. Always consult your doctor before taking this medicine during
You should not take Nac Sr 150mg Tablet with other nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen, as this significantly increases the risk of stomach ulcers and kidney damage. Talk to your doctor or pharmacist before combining any pain medications.
Do not increase your dose of Nac Sr 150mg Tablet on your own. If your pain does not improve, talk to your doctor so they can evaluate your treatment plan and explore other options safely.
Yes, Nac Sr 150mg Tablet can sometimes cause fluid retention, which can lead to an increase in blood pressure. It is important to monitor your blood pressure regularly while taking this medication. Talk to your doctor if you notice any unusual readings.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Drugs.com Clinical Review Team. Diclofenac Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  2. MedlinePlus. A689002 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026]Check here
  3. Diclofenac Diclofenac. 1998. [Accessed on 02 Apr. 2019]Check here
  4. Diclofenac sodium [Prescribing Information]. 2021. [Accessed on 06 Apr. 2024]Check here
  5. Cipla Limited. REACTIN® 100 SR Tablets – Product Information [Internet]. Mumbai: Cipla Limited; [Accessed on 2025 Sep 17]Check here
  6. Dexcel Pharma Ltd. Electronic Medicines Compendium (EMC). [Revised in March 2022] [Accessed on 29th July 2024]Check here
  7. Carlsbad Tech. Diclofenac sodium DR (75 mg tablets). Dailymed. [Revised in May 2016] [Accessed on 29th July 2024]Check here

Country of origin

India

Manufacturer/Marketer address

Systopic Laboratories Pvt. Ltd., 101, Pragati Chambers, Commercial Complex, Ranjit Nagar, New Delhi-110008
Other Info - NAC0024

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