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  3. Nacel 400 mg Injection 2 ml

Nacel 400 mg Injection 2 ml, Pack of 1 INJECTION
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Composition :

ACETYLCYSTEINE-400MG

Manufacturer/Marketer :

Celon Laboratories Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Nacel 400 mg Injection 2 ml

Nacel 400 mg Injection 2 ml is used to treat Paracetamol (acetaminophen) overdose and prevent liver injury. Paracetamol overdose may occur when the person takes more than 8 Paracetamol tablets in 24 hours accidentally or when intended to cause self-harm. If it is not treated promptly with an antidote, a significant overdose can lead to liver failure.

Nacel 400 mg Injection 2 ml contains Acetylcysteine, which works by restoring the levels of glutathione, a chemical that eliminates toxic substances.

Nacel 400 mg Injection 2 ml will be administered by a healthcare professional; do not self-administer. Some people may experience inflammation and pain at the injection site, nausea, vomiting, fever, excessive shivering, sweating, bruising, or bleeding more easily than normal. Most of these side effects of Nacel 400 mg Injection 2 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to Nacel 400 mg Injection 2 ml or any other medicines, please tell your doctor. Nacel 400 mg Injection 2 ml is given to children in doses advised by a doctor based on the child’s age and weight. If you are pregnant or breastfeeding, please inform your doctor before taking Nacel 400 mg Injection 2 ml. If you are about to undergo any surgery, inform the anaesthetist or surgeon that you are being treated with Nacel 400 mg Injection 2 ml.

Uses of Nacel 400 mg Injection 2 ml

Treatment of Paracetamol overdose

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.• Nacel 400 mg Injection 2 ml will be administered by the doctor.• Do not self-administer.

Medicinal Benefits

Nacel 400 mg Injection 2 ml is an antidote for Paracetamol (acetaminophen) overdose. It works by restoring the body’s glutathione, a chemical that eliminates toxic substances. Also, it protects the liver from damage caused due to high levels of paracetamol. Nacel 400 mg Injection 2 ml is very effective when given within 10 hours of paracetamol overdose.

How Nacel 400 mg Injection 2 ml Works

Nacel 400 mg Injection 2 ml contains Acetylcysteine, which works by restoring the levels of glutathione, a chemical that eliminates toxic substances.

Storage

Store in a cool and dry place away from sunlight
Side effects of Nacel 400 mg Injection 2 ml
Here are the steps to manage the medication-triggered Tachycardia (Fast Heart Rate):
  • Contact your doctor immediately if you're experiencing a fast heart rate, palpitations, or other heart-related symptoms. This is crucial to determine whether the symptoms are related to your medication.
  • Your doctor may need to adjust your medication regimen to alleviate the fast heart rate symptoms. This could involve changing the medication, reducing the dosage, or adding new medications to counteract the side effects.
  • Follow your doctor's advice on monitoring your heart rate and blood pressure. This will help track any changes and ensure your heart rate returns normal.
  • If you experience severe symptoms such as chest pain, dizziness, or shortness of breath, seek immediate medical attention. These symptoms can indicate a more serious condition that requires prompt treatment.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Wear loose-fitting clothes and breathable fabrics.
  • Keep your room cool by using a fan or AC.
  • Avoid or limit spicy food, alcohol and caffeine as they can trigger hot flashes.
  • Manage stress by practising relaxation techniques with yoga and meditation.
  • Quit smoking.
  • Maintain a healthy weight by including fruits and vegetables in your diet.
Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.

What if I have taken an overdose of Nacel 400 mg Injection 2 ml

Nacel 400 mg Injection 2 ml is administered by a health care professional in a hospital setting. Hence, the chances of overdose are less. Symptoms of overdose may include hemolysis, cerebral edema, status epilepticus, and death. Your doctor may take necessary measures if an overdose is suspected.

Drug Warnings

If you are allergic to Nacel 400 mg Injection 2 ml or any other medicines, please tell your doctor. Nacel 400 mg Injection 2 ml is given to children in doses advised by a doctor based on the child’s age and weight. If you are pregnant or breastfeeding, please inform your doctor before taking Nacel 400 mg Injection 2 ml. If you are about to undergo any surgery, inform the anaesthetist or surgeon/dentist that you are being treated with Nacel 400 mg Injection 2 ml. If you have a history of stomach ulcers or have asthma, inform your doctor before taking Nacel 400 mg Injection 2 ml.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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Diet & Lifestyle Advise

  • Do not take more than the Paracetamol dose mentioned on the label or prescribed by the doctor. 
  • Avoid giving Paracetamol to your child unless it is necessary for their fever or pain. 
  • For children below 2 years, use Paracetamol only in the dose advised by the doctor based on the child’s body weight.
  • Limit or avoid alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTIDOTES

Nacel 400 mg Injection 2 ml Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Interaction of alcohol with Nacel 400 mg Injection 2 ml is unknown. Please consult a doctor before consuming alcohol with Nacel 400 mg Injection 2 ml.

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Pregnancy

Caution

Nacel 400 mg Injection 2 ml is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

Nacel 400 mg Injection 2 ml is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.

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Driving

Safe if prescribed

Nacel 400 mg Injection 2 ml usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Nacel 400 mg Injection 2 ml should be used with caution if you have a history of Liver diseases/conditions. Your doctor will decide to administer Nacel 400 mg Injection 2 ml if the benefits are greater than the risks.

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Kidney

Caution

Nacel 400 mg Injection 2 ml should be used with caution if you have a history of Kidney diseases/conditions. Your doctor will decide to administer Nacel 400 mg Injection 2 ml if the benefits are greater than the risks.

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Children

Caution

Nacel 400 mg Injection 2 ml is given to children in doses advised by a doctor based on child’s age and weight.

Have a query?

FAQs

Nacel 400 mg Injection 2 ml is used to treat Paracetamol (acetaminophen) overdose and prevent liver injury.

Nacel 400 mg Injection 2 ml works by restoring the body’s glutathione, a chemical that eliminates toxic substances. Thus, it helps in the treatment of Paracetamol overdose.

You are recommended to inform your doctor or dentist that you have been treated with Nacel 400 mg Injection 2 ml if you are due to undergo any surgery or dental procedure because it may alter the effects of certain medicines that are used during anaesthesia.

Nacel 400 mg Injection 2 ml may interfere with reagent dipstick tests for urinary ketones giving false positive results. Therefore, if you are about to undergo any laboratory tests, inform your doctor or lab technician that you are taking Nacel 400 mg Injection 2 ml.

Nacel 400 mg Injection 2 ml may cause allergic reactions in some people. It is not necessary for everyone taking Nacel 400 mg Injection 2 ml to have allergic reactions. However, if you notice a skin rash, itching, flushing, difficulty breathing or swelling of the face, inform your doctor immediately.

Country of origin

India

Manufacturer/Marketer address

Plot No 264, Patrika Nagar Madhapur, Hitech City Hyderabad, Telangana India - 500081
Other Info - NAC0015

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 18, 2025 | 7:01 AM IST

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Reference

  1. https://www.nps.org.au/assets/medicines/b05f36a6-39c8-422c-99be-a53300ff3bcf.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/021539s004lbl.pdf
  3. https://www.medsafe.govt.nz/Profs/Datasheet/a/Acetylcysteineinj.pdf
  4. https://www.drugs.com/cdi/acetylcysteine-injection.html
  5. https://www.drugs.com/pro/acetylcysteine-injection.html

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