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Napro-ES 500 mg Capsule 10's is a painkiller medicine used to relieve pain. This combination medicine has anti-inflammatory properties which work by blocking the action of the body's cyclo-oxygenase (COX) enzyme to produce prostaglandins that cause pain and swelling. You may experience common side effects like indigestion, stomach pain, constipation, dizziness, nausea, and diarrhoea.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Manufacturer/Marketer :

RPG Life Sciences Ltd

Consume Type :

Oral

Return Policy :

Not Returnable

About Napro-ES 500 mg Capsule 10's

Napro-ES 500 mg Capsule 10's is an oral medication prescribed to relieve pain, swelling, and joint stiffness caused by chronic inflammatory conditions like arthritis. By combining a pain reliever with a protective stomach coating, it helps manage long-term discomfort while shielding your digestive system from irritation. It is designed to target both joint inflammation and stomach protection in a single pill.

To get the best results, it is important to take this medicine consistently every day exactly as your doctor directs. It is best taken at least 30 minutes before a meal to ensure the protective component can work effectively. Making simple lifestyle adjustments, such as maintaining a healthy weight and doing gentle joint-friendly exercises, can also support your overall physical function.

While many people tolerate this medication well, some may experience mild side effects like an upset stomach, nausea, or a mild headache. If you notice any serious side effects, such as dark or tarry stools, severe stomach pain, or a sudden allergic reaction, seek medical help immediately. Always consult your doctor if you experience any unusual symptoms while taking this medicine.

Talk to your doctor before starting this medication if you have a history of high blood pressure, heart disease, or kidney problems. Do not take this if you have severe liver damage, advanced kidney disease, or if you have ever had an asthma attack or severe allergic reaction to aspirin or other pain relievers. Your doctor will help determine if this is the safest option for your condition.

This medicine can interact with certain blood thinners and blood pressure drugs, so it is vital to share a complete list of your current medications with your healthcare team. Drinking alcohol or smoking while using this drug can significantly increase your risk of stomach bleeding. Pregnant women, breastfeeding mothers, and elderly individuals should always consult their doctor before starting this treatment.

Uses of Napro-ES 500 mg Capsule 10's

This medicine is used to relieve pain, reduce inflammation, and help protect the stomach lining during treatment. The detailed uses of Napro-ES 500 mg Capsule 10's are as follows:

  • Osteoarthritis: Helps reduce joint pain, stiffness, and swelling in daily wear-and-tear arthritis, allowing for easier movement.
  • Rheumatoid Arthritis: Eases chronic joint inflammation, pain, and swelling caused by autoimmune joint disease.
  • Ankylosing Spondylitis: Relieves spinal pain and stiffness, helping to improve back mobility and comfort.
  • Stomach Ulcer Prevention: Specifically protects the stomach lining from painful sores and ulcers that can occur when taking long-term pain relievers.

Key Benefits

This medicine helps relieve pain and inflammation while protecting the stomach from irritation. Its benefits include:

  • Helps reduce joint pain, swelling, and stiffness.
  • Improves mobility and makes everyday activities more comfortable.
  • Provides long-lasting relief from pain and inflammation.
  • Helps protect the stomach lining and lowers the risk of stomach ulcers caused by long-term pain-reliever use.
  • Combines pain relief and stomach protection in a single medicine for added convenience.
  • Supports a more active and comfortable lifestyle by improving physical function.

Directions for Use

  • Napro-ES 500 mg Capsule 10's should be taken on an empty stomach at least 30 minutes before a meal.
  • It is usually taken 2 times a day or as prescribed by your doctor.
  • Swallow Napro-ES 500 mg Capsule 10's as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Napro-ES 500 mg Capsule 10's Works

Napro-ES 500 mg Capsule 10's contains Esomeprazole and Naproxen. Esomeprazole: It is a proton pump inhibitor (PPI) that reduces the amount of acid produced in the stomach. This helps protect the stomach lining and lowers the risk of ulcers caused by long-term use of pain-relieving medicines. Naproxen: It is a nonsteroidal anti-inflammatory drug (NSAID) that blocks the production of chemicals responsible for pain, inflammation, and swelling, helping relieve joint pain and stiffness.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption with Napro-ES 500 mg Capsule 10's as it may increase the risk of stomach bleeding and ulcer.

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Pregnancy

Caution

There is limited data on how Napro-ES 500 mg Capsule 10's affects pregnancy. Please consult your doctor if you are planning to become pregnant or already pregnant before starting Napro-ES 500 mg Capsule 10's.

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Breast Feeding

Caution

Napro-ES 500 mg Capsule 10's passes into the breast milk. However, no evidence of risk has been reported. Please consult your doctor before intake of Napro-ES 500 mg Capsule 10's. Your doctor will weigh the benefits and any potential risks before prescribing Napro-ES 500 mg Capsule 10's to you.

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Driving

Caution

Napro-ES 500 mg Capsule 10's may cause dizziness, tiredness, drowsiness or vision problems in some people. So, drive only if you are alert after taking Napro-ES 500 mg Capsule 10's.

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Liver

Caution

Napro-ES 500 mg Capsule 10's is to be used with caution in people having liver diseases. Dose adjustments may be necessary. So, you should use it only with your doctor's prescription.

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Kidney

Caution

Napro-ES 500 mg Capsule 10's is not recommended for use in patients with moderate to severe and severe renal impairment. The dose may be adjusted by your doctor as required. So, it should be used only when prescribed by your doctor.

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Children

Caution

Napro-ES 500 mg Capsule 10's should be used in children below 12 years of age only when prescribed by a child specialist.

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Heart

Caution

Napro-ES 500 mg Capsule 10's should be taken with caution in patients with heart problems. Please inform your doctor if you have any pre-existing heart problems.

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Geriatrics

Caution

Napro-ES 500 mg Capsule 10's should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using Napro-ES 500 mg Capsule 10's.

What if I have taken an overdose of Napro-ES 500 mg Capsule 10's

If you suspect an overdose or experience severe symptoms like extreme drowsiness, nausea, vomiting, or breathing difficulties after taking too much of this medication, seek immediate medical attention or call your local poison control center.

Diet & Lifestyle Advise

  • Avoid alcohol and tobacco: Avoid drinking alcohol and using tobacco products, as both can increase the risk of stomach ulcers and serious stomach bleeding while taking this medicine.
  • Stay hydrated: Drink plenty of water throughout the day to support healthy kidney function.
  • Exercise regularly: Include low-impact activities such as walking, swimming, or cycling to help keep your joints flexible and strong.
  • Maintain a healthy diet: Eat a balanced diet rich in calcium and vitamin D, as long-term use of acid-reducing medicines may affect the absorption of these nutrients.
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How Soon It Starts Working

The time required for Napro-ES 500 mg Capsule 10's to start to work: Napro-ES 500 mg Capsule 10's ideally shows its action within 1 hour after administration. The time for which the effects of Napro-ES 500 mg Capsule 10's last: The effect of Napro-ES 500 mg Capsule 10's lasts for 24 hours.

What if you forget to take Napro-ES 500 mg Capsule 10's

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a missed tablet.

Storage

•Store Napro-ES 500 mg Capsule 10's tablets at room temperature, ideally between 68°F and 77°F (20°C to 25°C).

Drug Warnings

  • Monitor blood pressure: Check your blood pressure regularly, as this medicine may sometimes increase blood pressure.
  • Inform your healthcare provider: Tell your doctor, dentist, or surgeon that you are taking Napro-ES 500 mg Capsule 10's before any medical or surgical procedure.
  • Avoid other pain relievers: Do not take other over-the-counter pain relievers, such as ibuprofen or aspirin, unless your doctor advises you to.
  • Attend regular check-ups: If you use this medicine long term, your doctor may recommend regular blood tests or kidney function tests.
  • Seek immediate medical help: Stop taking this medicine and contact your doctor immediately if you develop persistent chest pain, shortness of breath, or slurred speech.

verifiedApollotooltip
  • Blood thinners: May increase the risk of severe stomach bleeding when taken with medications like warfarin or aspirin.
  • Blood pressure medications: Can reduce the effectiveness of certain blood pressure drugs, such as ACE inhibitors or beta-blockers.
  • Certain immune-modifying drugs: May increase the risk of kidney toxicity when combined with medications like methotrexate or cyclosporine.

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verifiedApollotooltip
  • High-fat meals: Taking this medication with a high-fat meal can delay how quickly your body absorbs the active ingredients, which is why it is recommended to take it on an empty stomach.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[NON-STEROIDAL DRUG]

FAQs

Napro-ES 500 mg Capsule 10's belongs to a group of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) or painkillers used to reduce and relieve pain.
Napro-ES 500 mg Capsule 10's contains Naproxen (NSAID or pain reliever) and esomeprazole (antacid). Naproxen works by blocking the release of certain chemical messengers (prostaglandins) that cause pain and inflammation (redness and swelling). Esomeprazole works by blocking the action of the enzyme known as the gastric proton pump that is responsible for the production of acid. This helps reduce the amount of acid produced, heals the ulcers and prevents the formation of new ulcers.
You are not recommended to take Napro-ES 500 mg Capsule 10's with clopidogrel as co-administration of these two medicines may increase the risk of bleeding more easily. However, please consult a doctor immediately if you notice blood in urine or stools, dizziness, unusual bleeding or bruising, vomiting, weakness or headache. If you are supposed to use these medicines together, you are advised to contact your doctor to adjust the dose appropriately to use safely.
Yes, Napro-ES 500 mg Capsule 10's can alter specific medical tests like neuroendocrine tumors (secretin stimulation test) and urine screening tests for tetrahydrocannabinol (THC). So before undergoing such diagnostics test, contact your doctor.
Naproxen in Napro-ES 500 mg Capsule 10's may increase the risk of heart problems such as heart attack and stroke especially when used in high doses or for a prolonged duration. It is advised to inform your doctor if you have any of these conditions or have a history of heart problems or stroke before taking Napro-ES 500 mg Capsule 10's. However, it is recommended to take Napro-ES 500 mg Capsule 10's in the dose and for the duration as prescribed by your doctor. It should be not used by the patient who had recent heart bypass surgery (coronary artery bypass graft - CABG).
Napro-ES 500 mg Capsule 10's does not cure arthritis but relieves symptoms of arthritis-like joint pain, swelling and stiffness. Arthritis is a chronic condition of joints with pain and inflammation.
Napro-ES 500 mg Capsule 10's is a pregnancy Category C medicine so, it is advisable to tell your doctor before its intake. It may inhibit ovulation (release of an egg from the ovary) and decrease the levels of progesterone leading to infertility in women. However, this effect is temporary and ovulation returns to normal mostly after one month of stopping Napro-ES 500 mg Capsule 10's. However, if you are planning for pregnancy or have difficulties becoming pregnant, please inform your doctor before taking Napro-ES 500 mg Capsule 10's.
It is highly recommended to take Napro-ES 500 mg Capsule 10's on an empty stomach, at least 30 minutes before a meal, to allow the protective coating to work properly. If you experience severe stomach upset, talk to your doctor.
It is best to avoid alcohol while taking this medicine, as combining them significantly increases your risk of developing stomach ulcers or internal bleeding. Talk to your doctor if you have concerns about this.
No, you should not take other nonsteroidal anti-inflammatory drugs (NSAIDs) while taking this medicine, as doing so greatly increases your risk of serious stomach side effects. Talk to your doctor or pharmacist before taking any new medications.
This medication is generally not recommended during pregnancy, especially during the last three months, as it can cause complications for the baby and during delivery. Talk to your doctor for safer alternatives.
Some people may experience mild dizziness or drowsiness while taking this medication. Avoid driving or operating machinery until you know how this medicine affects you, and talk to your doctor if these symptoms persist.
This medication is typically prescribed for chronic joint conditions like arthritis and is not meant for short-term, occasional pain like a simple headache. Talk to your doctor for guidance on appropriate headache treatments.
If your symptoms do not improve after a few weeks of consistent use, do not increase your dose on your own. Talk to your doctor to re-evaluate your treatment plan and discuss alternative options.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

463, 4 Th Floor, Rpg House, Dr. Annie Besant Road, Worli, Mumbai 400 030. Maharashtra, India
Other Info - NAP0286
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