apollo
logo
0
Select Delivery Location
compositionComposition:PEGFILGRASTIM-6MG
prescription
Prescription Medicine
info
Best Price

₹7517 with coupons & bank offers*

View

NC-UP 6 mg PFS Injection 0.6 ml belongs to the class of medicine called hematopoietic agents used in the treatment of neutropenia. It helps reduce the chances of infection in cancer patients by stimulating the formation of white blood cells. Common side effects include nausea, headaches, bone pain, pain in the extremity, and injection site reactions.

Read more
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
OffersOffers & Discounts

Get Free delivery (₹99) with circle icon

Join Circle
Get 18% Off with Coupons
Extra 10% Off with Bank Offers
bank offer
bank offer
bank offer

More about the Product

Composition :

PEGFILGRASTIM-6MG

Manufacturer/Marketer :

Halsted Pharma Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-29

Return Policy :

Not Returnable

About NC-UP 6 mg PFS Injection 0.6 ml

NC-UP 6 mg PFS Injection 0.6 ml is a prescription injection used to lower the risk of infection in patients with non-myeloid cancers who are receiving strong chemotherapy. It helps prevent a severe drop in certain infection-fighting white blood cells, known as neutrophils, which can often occur after chemotherapy treatments. By stimulating your body to produce more of these protective cells, this medicine shields you from potentially dangerous infections.

This medicine is typically given as a single injection during each chemotherapy cycle, usually 24 hours after your chemotherapy session. Staying highly consistent with your scheduled injection dates is critical for maintaining your body's immune defense throughout your cancer treatment. Because this is an injection, food intake does not affect how it works. Making simple lifestyle adjustments, such as staying thoroughly hydrated and practising strict hand hygiene, can significantly support your body during this treatment.

The most common side effect you may experience is temporary bone pain, which indicates that your bone marrow is actively producing new white blood cells. However, you must contact your doctor immediately if you experience severe left upper stomach pain, shoulder pain, or sudden breathing difficulties, as these are signs of serious complications. Always consult your healthcare provider if any side effect becomes severe or bothersome.

Before you begin using this medicine, it is important to talk to your doctor if you have a history of sickle cell disorders, kidney disease, or lung problems. Do not take this if you have had a severe allergic reaction to human granulocyte colony-stimulating factors or acrylic adhesives. Sharing your medical history helps ensure this therapy is safe for your specific condition.

This medicine does not have direct interactions with food, alcohol, or smoking, but consuming alcohol should be avoided as it can dehydrate your body and weaken your recovering immune system. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly patient, you should consult your healthcare provider to discuss the benefits and risks of using this injection.

Uses of NC-UP 6 mg PFS Injection 0.6 ml

NC-UP 6 mg PFS Injection 0.6 ml helps increase white blood cell production to reduce the risk of serious infections in people with low neutrophil counts. It may be used for:

  • Febrile neutropenia prevention in chemotherapy patients: NC-UP 6 mg PFS Injection 0.6 ml helps by stimulating your bone marrow to quickly produce more white blood cells, lowering your risk of developing a severe infection and fever while receiving chemotherapy.
  • Radiation-induced bone marrow suppression: In cases of accidental or high-dose radiation exposure, NC-UP 6 mg PFS Injection 0.6 ml helps speed up the recovery of damaged white blood cells to protect the body against life-threatening infections.
     

Key Benefits

NC-UP 6 mg PFS Injection 0.6 ml helps reduce the risk of serious infections, supports uninterrupted cancer treatment, and promotes faster recovery of white blood cells. Key benefits include:

  • Reduces the risk of infection: Increases neutrophil levels, helping lower the risk of serious infections and febrile neutropenia during chemotherapy.
  • Supports uninterrupted chemotherapy: Helps maintain adequate white blood cell counts, reducing the need to delay or reduce chemotherapy doses.
  • May reduce hospitalisation: Lowers the likelihood of severe infections that require emergency hospital care or intravenous antibiotics.
  • Provides long-lasting protection: A single injection offers prolonged support throughout the chemotherapy cycle, reducing the need for frequent injections.
Side effects of Nc-up 6mg Pfs Inj 0.6ml
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Regular exercise, like swimming, walking, and yoga, can help reduce bone pain by strengthening muscles and releasing natural pain relievers.
  • Physical therapy, including stretching, strengthening exercises, TENS (a type of therapy using electrical pulses), and massage, can help ease bone pain and improve movement.
  • Mind-body techniques, like relaxation, meditation, and hypnosis, can reduce pain and help control muscle tension that comes with bone pain.
  • Acupuncture may help reduce bone pain by triggering the release of natural painkillers and easing nerve discomfort.
  • Avoid sitting for long periods; take short walks or stretch regularly.
  • Herbs like turmeric and ginger might help with bone pain.
  • Eat a diet rich in calcium, vitamin D, and protein for strong bones and muscles.
  • Quit smoking and limit alcohol.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Regular exercise, like swimming, walking, and yoga, can help reduce bone pain by strengthening muscles and releasing natural pain relievers.
  • Physical therapy, including stretching, strengthening exercises, TENS (a type of therapy using electrical pulses), and massage, can help ease bone pain and improve movement.
  • Mind-body techniques, like relaxation, meditation, and hypnosis, can reduce pain and help control muscle tension that comes with bone pain.
  • Acupuncture may help reduce bone pain by triggering the release of natural painkillers and easing nerve discomfort.
  • Avoid sitting for long periods; take short walks or stretch regularly.
  • Herbs like turmeric and ginger might help with bone pain.
  • Eat a diet rich in calcium, vitamin D, and protein for strong bones and muscles.
  • Quit smoking and limit alcohol.
  • Incorporate foods high in antioxidants, such as tomatoes, leafy greens, and berries, to prevent inflammation.
  • Encourage stress-relieving activities like yoga, deep breathing, and meditation.
  • Support the immune system and help the body rid itself of toxins.
  • Regularly check white blood cell counts to monitor the effectiveness of therapy and make any necessary modifications.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • NC-UP 6 mg PFS Injection 0.6 ml may be administered by your doctor, or you may be told to inject the medication yourself at home. Your doctor will train you on how to use NC-UP 6 mg PFS Injection 0.6 ml at home.
  • Check the label for directions and use it as advised by the doctor.
  • NC-UP 6 mg PFS Injection 0.6 ml should be administered subcutaneously (under the skin) in the thighs, abdomen, buttocks, or upper arm.
  • Rotate the injection site each time.
  • Do not inject into the areas where the skin is tender, red, bruised, hard, scarred, or has stretch marks.

How NC-UP 6 mg PFS Injection 0.6 ml Works

NC-UP 6 mg PFS Injection 0.6 ml contains pegfilgrastim, which works by stimulating the bone marrow to produce more neutrophils (a type of white blood cell), helping reduce the risk of serious infections during chemotherapy. NC-UP 6 mg PFS Injection 0.6 ml is a long-acting form of granulocyte colony-stimulating factor (G-CSF). It binds to receptors in the bone marrow and stimulates the production, maturation, and release of neutrophils into the bloodstream. This helps restore low white blood cell counts caused by chemotherapy or radiation exposure, providing prolonged protection against infection with a single injection per chemotherapy cycle.
bannner image

Alcohol

Caution

It is unknown whether consuming alcohol with NC-UP 6 mg PFS Injection 0.6 ml is safe. However, as a precaution, it is best to avoid or limit alcohol consumption.

bannner image

Pregnancy

Caution

Pregnancy Category C. It should be used in pregnant women only if clinically needed, and the benefits outweigh the risks. Please consult your doctor.

bannner image

Breast Feeding

Caution

It is unknown whether NC-UP 6 mg PFS Injection 0.6 ml passes into the breast milk. Please seek medical advice from your doctor if you are breastfeeding before taking NC-UP 6 mg PFS Injection 0.6 ml.

bannner image

Driving

Safe if prescribed

The ability to drive or utilize machines is unaffected by NC-UP 6 mg PFS Injection 0.6 ml.

bannner image

Liver

Caution

Consult your doctor if you have liver problems.

bannner image

Kidney

Caution

Caution should be exercised while using NC-UP 6 mg PFS Injection 0.6 ml in patients with renal dysfunction. Monitoring of patients with renal dysfunction is recommended.

bannner image

Children

Caution

Please consult your doctor if you have any concerns regarding the usage of NC-UP 6 mg PFS Injection 0.6 ml in children.

bannner image

Heart

Caution

NC-UP 6 mg PFS Injection 0.6 ml should be used with caution in patients with heart conditions, as it may increase the risk of side effects. Please inform your doctor if you have any heart problems before receiving NC-UP 6 mg PFS Injection 0.6 ml.

bannner image

Geriatrics

Caution

NC-UP 6 mg PFS Injection 0.6 ml should be administered with caution in elderly patients due to an increased risk of side effects. Seek medical advice if you have any concerns.

What if I have taken an overdose of NC-UP 6 mg PFS Injection 0.6 ml

If you accidentally inject more than the prescribed dose of NC-UP 6 mg PFS Injection 0.6 ml, seek immediate medical attention. Even if you do not have any symptoms, contact your doctor or go to the nearest emergency department as soon as possible.

Diet & Lifestyle Advise

  • Practice strict hand hygiene: Wash your hands thoroughly with soap and water throughout the day, especially before eating and after using public spaces, to minimize your exposure to bacteria.
  • Eat fully cooked foods: Avoid raw meats, raw seafood, runny eggs, and unpasteurized dairy products, as these can carry bacteria that your recovering immune system might struggle to fight.
  • Avoid crowded places: Limit your exposure to large crowds and individuals showing symptoms of cold, flu, or other contagious illnesses during your chemotherapy cycles.
  • Stay well-hydrated: Drink plenty of water and clear fluids daily to support your kidneys and help your body process your treatments effectively.
  • Engage in gentle movement: Light stretching or walking can help ease the temporary bone and joint pain that often occurs as your bone marrow works to produce new cells.
health query

Have a query?

How Soon It Starts Working

The time required for NC-UP 6 mg PFS Injection 0.6 ml to start to work: NC-UP 6 mg PFS Injection 0.6 ml ideally shows its action within 24 hours after administration. The time for which the effects of NC-UP 6 mg PFS Injection 0.6 ml last: The effect of NC-UP 6 mg PFS Injection 0.6 ml lasts for several days.

What if you forget to take NC-UP 6 mg PFS Injection 0.6 ml

If you miss your scheduled injection, contact your doctor or pharmacist immediately. Because this medicine must be carefully timed in relation to your chemotherapy sessions, your healthcare team will advise you on the safest time to receive your missed dose. Do not take a double dose to make up for a missed one.

Storage

•Store NC-UP 6 mg PFS Injection 0.6 ml in a refrigerator between 2°C and 8°C in its original carton to protect it from light.•Do not freeze this medicine. If the syringe has been frozen, do not use it.

Drug Warnings

  • Check the expiry date: Always check the expiry date before using NC-UP 6 mg PFS Injection 0.6 ml. Do not use it if it has expired.
  • Do not shake the syringe: Never shake the prefilled syringe, as this may damage the medicine.
  • Rotate injection sites: Use a different injection site each time and avoid injecting into skin that is bruised, tender, red, or hard.
  • Never reuse injection equipment: Use a new needle or prefilled syringe for each injection and dispose of it safely after use.
  • Follow the correct timing: Inject NC-UP 6 mg PFS Injection 0.6 ml at least 24 hours after completing chemotherapy and not within 14 days before your next chemotherapy session.

Drug-Drug Interactions

verifiedApollotooltip
  • Lithium: Taking NC-UP 6 mg PFS Injection 0.6 ml with lithium may further increase white blood cell counts and requires careful monitoring by your doctor.
  • Other bone marrow-stimulating medicines: Using NC-UP 6 mg PFS Injection 0.6 ml with other granulocyte colony-stimulating factors (G-CSFs) or medicines that stimulate bone marrow may increase the risk of excessively high white blood cell counts.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

Login/Sign Up

Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with NC-UP 6 mg PFS Injection 0.6 ml when used as directed. 

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Habit Forming

No

Therapeutic Class

[HEMATOPOIETIC]

FAQs

NC-UP 6 mg PFS Injection 0.6 ml belongs to the class of medicine called 'hematopoietic agent' used to treat neutropenia, a deficiency of specific white blood cells caused by cancer, bone marrow transplant, chemotherapy, or other diseases.
NC-UP 6 mg PFS Injection 0.6 ml contains 'Pegfilgrastim,' which is a growth factor that stimulates the formation of white blood cells and helps to reduce the chances of infection in cancer patients receiving chemotherapy.
This medication should not be used in individuals who have a known allergy to filgrastim, pegfilgrastim, or any of the inactive components present in it.
Yes, NC-UP 6 mg PFS Injection 0.6 ml may interfere with certain lab tests, such as bone imaging and blood testing, potentially resulting in incorrect test findings. Make sure your doctor and laboratory personnel are aware that you take NC-UP 6 mg PFS Injection 0.6 ml.
NC-UP 6 mg PFS Injection 0.6 ml may sometimes cause capillary leak syndrome, a condition that causes blood leakage from small blood vessels. Inform your doctor immediately if you notice difficulty breathing, swelling, a feeling of fullness, and tiredness.
Yes, you can self-inject if your healthcare provider trains you on proper technique, safety, and disposal. Do not attempt to inject yourself until you feel completely confident in doing so. Talk to your doctor or pharmacist if you need a demonstration.
Bone pain is a common sign that the medicine is working. It stimulates your bone marrow to quickly produce a large number of new white blood cells, which can create temporary pressure and pain inside your bones. Talk to your doctor about safe over-the-counter pain relievers you can use.
Because this medicine must be precisely timed with your chemotherapy cycle, missing a dose requires immediate guidance. Contact your healthcare provider right away to reschedule. Talk to your doctor or pharmacist for custom advice on your chemotherapy schedule.
The safety of this medicine during pregnancy or breastfeeding is not fully established. It should only be used if the potential benefit justifies the risk to the baby. Talk to your doctor to evaluate your options safely.
When traveling, keep the medicine in its original packaging inside a cool travel pack with ice packs, ensuring it does not freeze. Avoid exposing it to extreme heat or direct light. Talk to your pharmacist for specific travel storage tips.
While there is no direct interaction between this medicine and alcohol, alcohol can dehydrate you and strain your recovery during chemotherapy. Talk to your doctor before consuming alcohol during your treatment.
No, this medicine does not treat or cure cancer itself. It is a supportive therapy designed to protect your immune system and prevent life-threatening infections while you undergo cancer treatments. Talk to your doctor to learn more about how it fits into your overall treatment plan.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Ground floor, Plot No.25-HIG, Survey No.912P. 913P, 941P, 944P 945 to 962 and 964P Phase XV, KPHB Colony, Kukatpally. Medchal- Malkajgiri District, Telangana State, India
Other Info - NCU0006
whatsapp Floating Button
Buy Now
Add to Cart