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Nebifine-AM Tablet is used to treat high blood pressure and reduce the further risk of heart attack or stroke. It lowers blood pressure and reduces the risk of stroke, heart attack, other heart problems, or kidney problems in the future. It contains S Amlodipine and Nebivolol, which relaxes the blood vessels and reduces the heart's workload, making the heart more efficient at pumping blood throughout the body. Some people may experience headaches, feeling exhausted and swollen ankles. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Troikaa Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Nebifine-AM Tablet

Nebifine-AM Tablet is an oral prescription medicine used to treat high blood pressure (hypertension). By lowering elevated blood pressure, this medication helps protect your cardiovascular system and reduces the risk of serious complications like heart attacks or strokes. It combines two highly effective blood pressure-lowering medicines into a single, convenient tablet.

To get the best results, you must take Nebifine-AM Tablet consistently at the same time every day. It can be taken with or without food, depending on your preference or your doctor's advice. Combining this treatment with lifestyle adjustments, such as eating a low-salt diet, exercising regularly, and managing daily stress, greatly enhances its effectiveness.

While taking Nebifine-AM Tablet , some people may experience mild side effects like dizziness, ankle swelling, or tiredness. These symptoms often improve as your body adjusts to the medicine, but you should contact your doctor immediately if you notice severe shortness of breath, an unusually slow heartbeat, or chest pain.

Before you start taking Nebifine-AM Tablet , it is crucial to discuss your complete medical history with your healthcare provider, especially if you have a history of heart failure, blood circulation issues, or lung conditions. Do not take this if you have a very slow heart rate, severe heart block, or severe liver damage.

This medication can interact with other drugs, alcohol, and tobacco, which may either reduce its effectiveness or dangerously lower your blood pressure. Pregnant or breastfeeding women, as well as elderly individuals, should consult their doctor before starting this medication to ensure it is safe for their specific needs.

Uses of Nebifine-AM Tablet

Nebifine-AM Tablet is used to treat high blood pressure (hypertension). The detailed uses of Nebifine-AM Tablet are as follows:

  • High blood pressure (Hypertension): Nebifine-AM Tablet helps lower elevated blood pressure, which reduces the workload on your heart and protects your blood vessels from long-term damage.
     

Key Benefits

Nebifine-AM Tablet helps manage high blood pressure by providing effective and sustained blood pressure control. By combining two complementary blood pressure-lowering actions, it supports long-term cardiovascular health and helps protect vital organs from the effects of hypertension.

  • Helps Maintain Healthy Blood Pressure Levels: By lowering and controlling elevated blood pressure, Nebifine-AM Tablet helps reduce strain on the heart and blood vessels, supporting stable blood pressure throughout the day and night.
  • Supports Long-Term Heart, Brain, and Kidney Health: Effective blood pressure control with Nebifine-AM Tablet helps reduce the risk of complications such as heart attack, stroke, heart failure, and kidney damage, promoting long-term cardiovascular and overall health.
  • Provides Consistent All-Day Blood Pressure Control: With its dual-action approach, Nebifine-AM Tablet helps maintain smooth and reliable blood pressure control throughout the day, supporting better physical wellbeing and helping you stay active with confidence.
     

Directions for Use

  • Nebifine-AM Tablet can be taken with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow it as a whole with a glass of water.
  • Do not chew, crush, or break it.

How Nebifine-AM Tablet Works

Nebifine-AM Tablet works by combining two different active ingredients that target blood pressure in two distinct ways, providing a more comprehensive effect than either ingredient alone. The first active component, nebivolol, belongs to a class of medicines called beta-blockers. It works by blocking certain chemical signals in the body, which slows down your heart rate and allows the heart to pump blood more efficiently with less effort. It also helps widen the blood vessels slightly by releasing a natural substance called nitric oxide. The second active component, s-amlodipine, is a calcium channel blocker. It prevents calcium from entering the muscle cells of your blood vessels. This action relaxes and widens the blood vessels, allowing blood to flow through them much more easily. Together, these two mechanisms reduce the pressure within your cardiovascular system and make it easier for your heart to distribute blood throughout your body.
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Nebifine-AM Tablet to avoid unpleasant side-effects.

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Pregnancy

Unsafe

Nebifine-AM Tablet should not be taken until prescribed. Nebifine-AM Tablet can have some harmful effects on the baby (fetus); your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

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Breast Feeding

Caution

Nebifine-AM Tablet is usually not recommended in breastfeeding mothers. Limited human data available suggests that the drug does not do any significant harm to the baby. Consume only if benefits outweigh risks.

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Driving

Unsafe

It is not recommended to drive after taking Nebifine-AM Tablet as it may occasionally cause drowsiness or fatigue.

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Liver

Caution

Nebifine-AM Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Nebifine-AM Tablet to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Nebifine-AM Tablet is not recommended in children below the age of 6 years. The safety and efficacy of Nebifine-AM Tablet in children have not yet been established.

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Heart

Safe if prescribed

Nebifine-AM Tablet is safe for use in heart patients if recommended by the physician.

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Geriatrics

Caution

Nebifine-AM Tablet should be used under caution in geriatric patients. Please consult your physician.

What if I have taken an overdose of Nebifine-AM Tablet

If you take more than your prescribed dose, seek emergency medical attention immediately. An overdose can cause your blood pressure and heart rate to drop dangerously low, leading to symptoms like severe dizziness, fainting, weakness, or difficulty breathing.

Diet & Lifestyle Advise

To get the most benefit from Nebifine-AM Tablet , consider incorporating these heart-healthy habits into your daily routine:

  • Reduce your salt intake: Limit high-sodium foods, processed meats, and canned goods, as sodium causes the body to retain water and increases blood pressure.
  • Eat a heart-healthy diet: Focus on whole grains, fresh fruits, vegetables, lean proteins, and low-fat dairy.
  • Stay active: Engage in moderate aerobic exercise, such as brisk walking, cycling, or swimming, for at least 30 minutes most days of the week, after getting your doctor's approval.
  • Manage stress: Practice relaxation techniques such as deep breathing, meditation, or yoga to help keep your blood pressure stable.
  • Avoid smoking and limit alcohol: Smoking damages your blood vessels, and excessive alcohol can raise your blood pressure and interfere with your medication.
     
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How Soon It Starts Working

The time required for Nebifine-AM Tablet to start to work: The time required for Nebifine-AM Tablet to start to work is 2 hours after administration. The time for which the effects of Nebifine-AM Tablet last: The effect of Nebifine-AM Tablet lasts for 24 hours.

What if you forget to take Nebifine-AM Tablet

If you miss a dose, take it as soon as you remember. However, if your next scheduled dose is less than 12 hours away, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.

Storage

•Store the tablets at room temperature, ideally below 30°C (86°F). •Keep the medication in its original packaging to protect it from moisture and direct light.

Drug Warnings

  • Always check your tablet blister pack before use to ensure the tablets are intact and undamaged.
  • Do not stop taking Nebifine-AM Tablet suddenly, as doing so can cause a severe, sudden rise in your blood pressure, which can be dangerous.
  • If you need to stop this treatment, your doctor will advise you on how to do so by gradually increasing dose or tapering off safely.
  • Stand up slowly from a sitting or lying position to minimize the risk of dizziness or falling, especially when you first start taking this medicine.
  • Avoid driving or operating machinery if you feel dizzy or sleepy after taking your dose.
  • Monitor your blood pressure at home regularly and keep a log to share with your doctor during your checkups.
     

Drug-Drug Interactions

verifiedApollotooltip
  • Other blood pressure medications: Combining this medicine with other antihypertensives can cause your blood pressure to fall too low.
  • Heart rhythm medications (such as digoxin or amiodarone): Taking these alongside Nebifine-AM Tablet can cause an excessively slow heart rate.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs like ibuprofen): These can reduce the blood pressure-lowering effect of your medicine.
  • Certain antidepressants: Some mood-stabilising medications can increase the levels of this medicine in your body, raising the risk of side effects.
     
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip
  • Grapefruit and grapefruit juice: Avoid consuming grapefruit, as it can increase the amount of s-amlodipine in your body, which can cause a sudden, dangerous drop in blood pressure.
  • Alcohol: Avoid or limit alcohol consumption, as it can worsen dizziness and drowsiness when combined with this medication.

 

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

FAQs

Nebifine-AM Tablet is used to treat high blood pressure and reduce the further risk of heart attack or stroke.
Nebifine-AM Tablet is a combination drug containing, S Amlodipine (calcium channel blocker) and Nebivolol (beta-blocker). Both relax the blood vessels, which lowers your blood pressure and reduces your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future.
Your doctor may probably tell you to stop taking Nebifine-AM Tablet as it lowers blood pressure (hypotension) when combined with general anesthesia before surgery. So, please inform your doctor before surgery if you are taking Nebifine-AM Tablet .
Yes, Nebifine-AM Tablet is known to cause ankle swelling. Please try to keep your feet up when sitting for long hours. If the problem persists still, consult your doctor and do as advised.
Yes, Nebifine-AM Tablet can cause dry mouth. Therefore, it is always advised to increase fluid intake while taking Nebifine-AM Tablet . If you still feel excessively thirsty, please consult your doctor and do as advised for best results of Nebifine-AM Tablet .
Common side effects of Nebifine-AM Tablet may include, headaches, feeling exhausted, and swollen ankles. Most of these side effects of Nebifine-AM Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Yes, you can take Nebifine-AM Tablet with food. It will not affect the medication's effectiveness.
Swallow it as a whole with a glass of water. Do not crush, chew, or break it.
The dosage of Nebifine-AM Tablet will depend on your individual needs and medical history. Your doctor will prescribe the appropriate dosage based on your blood pressure levels and other factors.
No, Nebifine-AM Tablet is not an antibiotic medication. Nebifine-AM Tablet belongs to antihypertensive class medication.
Avoid salty foods, red meat, processed meats, and foods high in saturated and trans fats. These can worsen high blood pressure. Limit alcohol and caffeinated beverages.
Unhealthy diet can cause high blood pressure. Too much salt, unhealthy fats, and processed foods can increase your risk. Eating fruits, vegetables, and whole grains can help lower blood pressure.
Elevated blood pressure is blood pressure that is slightly higher than normal. If your blood pressure is between 120/80 mmHg and 129/80 mmHg, you have elevated blood pressure.
Risk factors that can increase your risk of high blood pressure include health conditions, your lifestyle, and your family history. Some of the risk factors for high blood pressure cannot be controlled, such as your age or family history. But you can take steps to lower your risk by changing the factors you can control.
No, you should never stop taking Nebifine-AM Tablet without consulting your doctor. High blood pressure often has no symptoms, so you may feel perfectly fine while the medicine is doing its job. Stopping the drug suddenly can cause your blood pressure to spike dangerously. Talk to your doctor if you have concerns about your treatment.
It is best to avoid or limit alcohol while taking Nebifine-AM Tablet . Alcohol can increase the blood pressure-lowering effect of the medicine, making you feel excessively dizzy, lightheaded, or sleepy. If you choose to drink, talk to your doctor about what is safe for you.
Certain pain relievers, specifically nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen, can reduce the effectiveness of Nebifine-AM Tablet in lowering your blood pressure. They can also affect your kidney function. If you need pain relief, talk to your doctor or pharmacist to find a safer alternative.
Generally, Nebifine-AM Tablet is not recommended during pregnancy or breastfeeding as it may harm the developing baby. If you are pregnant, planning to become pregnant, or breastfeeding, you must discuss alternative options with your healthcare provider. Talk to your doctor for safe alternatives.
Grapefruit and its juice interfere with how your body processes one of the active ingredients in Nebifine-AM Tablet . This can cause the medicine's levels to rise too high in your bloodstream, leading to a sudden, severe drop in blood pressure and increased side effects. Talk to your doctor if you have questions about your diet.
Yes, feeling cold in your hands or feet is a common side effect of the beta-blocker component in Nebifine-AM Tablet . It happens because the medicine diverts blood flow slightly away from your extremities to protect your main organs. If this becomes highly uncomfortable or if your skin changes colour, talk to your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Triton Healthcare Pvt Ltd, Plot No. 75, Natarajan Street, Dhanalakshmi Colony, Vadapalani, Chennai - 600 026.
Other Info - NEB0190
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