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compositionComposition:CILNIDIPINE-10MG+NEBIVOLOL-5MG
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Prescription Medicine
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Nebivol-CL Tablet 10's is used to treat high blood pressure. It contains Cilnidipine and Nebivolol, which allow the blood to flow more smoothly and the heart to pump more efficiently. Additionally, it works by slowing down the heart rate to enhance blood circulation and lower blood pressure. In some cases, you may experience side effects such as headache, nausea, dizziness, tiredness, increased potassium level, constipation, oedema, cold extremities, and low blood pressure. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CILNIDIPINE-10MG+NEBIVOLOL-5MG

Manufacturer/Marketer :

Knoll Healthcare Pvt Ltd

Consume Type :

Oral

Return Policy :

Not Returnable

About Nebivol-CL Tablet 10's

Nebivol-CL Tablet 10's is a prescription medication used to treat high blood pressure (hypertension). It combines two active ingredients that work together to lower blood pressure, helping to reduce the workload on your heart. By keeping your blood pressure within a healthy range, this medication helps prevent serious long-term complications such as heart attacks, strokes, and kidney problems.

For the best results, you must take Nebivol-CL Tablet 10's consistently every day, exactly as prescribed by your doctor. It is typically taken once daily and can be taken with or without food. To get the maximum benefit from your treatment, it is highly recommended to combine this medicine with healthy lifestyle choices, such as eating a low-salt diet, maintaining a healthy weight, and staying physically active.

Like many blood pressure medicines, Nebivol-CL Tablet 10's can cause some mild side effects, such as headaches, mild swelling in the ankles, or feeling unusually tired. Most of these effects improve as your body adjusts to the medication. However, if you experience more serious symptoms like an extremely slow heart rate, severe dizziness, or chest pain, you should contact your doctor immediately.

Before you start taking this medicine, it is important to discuss your medical history with your doctor. Do not take this if you have severe liver damage, a very slow heart rate, serious heart block, or cardiogenic shock. It is also crucial to tell your doctor if you have a history of asthma, lung disease, or blood circulation problems in your limbs.

Nebivol-CL Tablet 10's can interact with other substances, including alcohol, which can cause your blood pressure to drop too low and make you feel dizzy or faint. Let your doctor know about all other medicines you are taking, especially other heart drugs, water pills, or antidepressants. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly patient, consult your healthcare provider to ensure this treatment is safe for you.

Uses of Nebivol-CL Tablet 10's

Nebivol-CL Tablet 10's may be prescribed for the following conditions: 

  • Hypertension (High Blood Pressure): Nebivol-CL Tablet 10's is primarily prescribed to lower elevated blood pressure, reducing the strain on your cardiovascular system and lowering your risk of long-term complications.
  • Prevention of Stroke and Heart Attack: By consistently keeping your blood pressure within a normal, controlled range, Nebivol-CL Tablet 10's helps protect your blood vessels and heart from damage.

Key Benefits

Nebivol-CL Tablet 10's combines two blood pressure-lowering medicines that work together to provide effective cardiovascular protection and support long-term heart health.

  • Lowers Blood Pressure Effectively: Helps control high blood pressure through complementary mechanisms, providing stable blood pressure management.
  • Protects the Heart and Blood Vessels: Reduces strain on the cardiovascular system and helps lower the risk of complications associated with uncontrolled hypertension.
  • Supports Kidney Health: May help protect kidney function, particularly in individuals with hypertension and certain underlying conditions such as diabetes.
  • Promotes Comfortable Blood Flow: Helps relax and widen blood vessels, improving circulation without causing a significant increase in heart rate.
  • Simplifies Treatment: Combining two medicines in one tablet may improve treatment convenience and adherence.

Directions for Use

  • Nebivol-CL Tablet 10's can be taken with or without food, as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Nebivol-CL Tablet 10's as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Nebivol-CL Tablet 10's Works

Nebivol-CL Tablet 10's contains cilnidipine and nebivolol, which work together to help lower blood pressure through complementary mechanisms. Cilnidipine is a calcium channel blocker that relaxes and widens blood vessels by reducing the entry of calcium into the muscle cells of blood vessel walls. It also acts on nerve endings, helping to reduce the release of substances that can cause blood vessels to narrow and the heart to work harder. Nebivolol is a selective beta-blocker that helps slow the heart rate and reduces the force with which the heart pumps blood. It also promotes the release of nitric oxide, a natural substance that helps relax and widen blood vessels, further improving blood flow. Together, these actions help lower blood pressure, reduce the workload on the heart, and support overall cardiovascular health.
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Alcohol

Unsafe

Taking this medicine with alcohol may lead to decreased blood pressure. Therefore, avoid alcohol consumption.

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Pregnancy

Consult your doctor

It should not be used during pregnancy unless clearly necessary. Consult a doctor before taking the medicine.

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Breast Feeding

Consult your doctor

Doctors consultation is recommended as there is no data available on whether this drug is passed through the mother's milk to the infant.

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Driving

Caution

It may cause sleepiness and drowsiness. Drive only if you are alert.

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Liver

Consult your doctor

Please consult the doctor if you have any concerns regarding the usage of Nebivol-CL Tablet 10's in patients with liver problems.

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Kidney

Consult your doctor

Please consult the doctor if you have any concerns about using Nebivol-CL Tablet 10's in patients with kidney problems.

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Children

Unsafe

It is not to be used in children below 12 years as there have been cases of harmful interactions.

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Heart

Safe if prescribed

Nebivol-CL Tablet 10's is safe for use in heart patients if recommended by the physician.

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Geriatrics

Caution

Nebivol-CL Tablet 10's should be used under caution in geriatric patients. Please consult your physician.

What if I have taken an overdose of Nebivol-CL Tablet 10's

If you suspect an overdose, seek immediate medical attention or visit the nearest emergency room. Symptoms of an overdose can include severe dizziness, fainting, an extremely slow heartbeat, or feeling unusually weak.

Diet & Lifestyle Advise

  • Reduce Salt Intake: Limit your consumption of processed and salty foods, as excess sodium directly raises blood pressure and can make your medication less effective.
  • Stay Active: Aim for at least 150 minutes of moderate-intensity exercise, such as brisk walking, every week. Always discuss new exercise routines with your doctor first.
  • Limit Alcohol: Keep alcohol consumption to a minimum, as drinking alcohol can cause a sudden, unsafe drop in blood pressure when combined with this medicine.
  • Avoid Smoking: Quit smoking, as nicotine constricts your blood vessels, raises your heart rate, and counteracts the beneficial cardiovascular effects of Nebivol-CL Tablet 10's.
  • Manage Stress: Practice relaxation techniques such as deep breathing, meditation, or yoga to help keep your stress levels and blood pressure low.
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How Soon It Starts Working

  • The time required for Nebivol-CL Tablet 10's to start to work: The time required for Nebivol-CL Tablet 10's to show its action is unknown.
  • The time for which the effects of Nebivol-CL Tablet 10's last: The duration of action for Nebivol-CL Tablet 10's is unknown.

What if you forget to take Nebivol-CL Tablet 10's

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Storage

• Store Nebivol-CL Tablet 10's tablets at room temperature, ideally between 20°C and 25°C (68°F to 77°F). • Keep the medication in its original blister pack or container to protect it from moisture and direct sunlight.

Drug Warnings

  • Monitor Blood Pressure and Heart Rate: Check your blood pressure and pulse regularly and maintain a record to share with your healthcare provider.
  • Do Not Stop Treatment Suddenly: Abrupt discontinuation may cause a rebound increase in blood pressure, chest pain, or a rapid heart rate. Follow your doctor's instructions if treatment needs to be stopped.
  • Stand Up Slowly: Rise gradually from sitting or lying positions to help reduce dizziness and prevent falls.
  • Monitor Blood Sugar if You Have Diabetes: This medicine may mask some symptoms of low blood sugar, such as a rapid heartbeat.
  • Inform Healthcare Providers: Tell your doctor, dentist, surgeon, or anaesthesiologist that you are taking Nebivol-CL Tablet 10's before any medical or surgical procedure.

verifiedApollotooltip

Inform your doctor if you are taking any of the following medicines, as they may interact with Nebivol-CL Tablet 10's: 

  • Other Blood Pressure Drugs: Taking other medications that lower blood pressure at the same time may cause your blood pressure to drop too low, leading to severe dizziness or fainting.
  • Heart Rhythm Medicines: Medicines like amiodarone or digoxin can cause your heart rate to slow down to dangerous levels when taken with Nebivol-CL Tablet 10's.
  • Pain Relievers (NSAIDs): Regularly taking non-steroidal anti-inflammatory drugs like ibuprofen or naproxen can reduce the blood-pressure-lowering effectiveness of this medicine.
  • Certain Antidepressants: Medications like fluoxetine or paroxetine can increase the levels of nebivolol in your blood, making side effects more likely.

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verifiedApollotooltip

Certain foods and beverages may affect how Nebivol-CL Tablet 10's works or increase the likelihood of side effects: 

  • Grapefruit and Grapefruit Juice: Grapefruit can significantly increase the levels of cilnidipine in your body, which may cause your blood pressure to drop unexpectedly low.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

FAQs

Nebivol-CL Tablet 10's is used to treat high blood pressure. It helps lower blood pressure by relaxing the blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently.
If you forget to take a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take a double dose to make up for a forgotten dose.
Nebivol-CL Tablet 10's and contraceptives as such are safe to use as no interaction between them has been reported, yet doctor consultation is recommended.
It may contain ingredients derived from animal sources, such as glucosamine and chondroitin, which are typically sourced from shellfish and animal cartilage. Please check with your healthcare professional for if you have any questions.
Nebivol-CL Tablet 10's is generally well-tolerated and may cause some mild side effects, such as headache, tiredness, nausea, abdominal pain, indigestion, diarrhoea, and constipation. The good news is that these side effects are usually temporary and will resolve on their own over time. If you experience any persistent discomfort, it's always a good idea to consult with your doctor for personalized guidance.
Storage: Nebivol-CL Tablet 10's should be stored in a cool, dry place away from direct sunlight, ideally at temperatures between 10°C to 25°C. Keep the medication in its original container, tightly closed, and out of reach of children and pets. Disposal: Do not flush the medication down the toilet or pour it into a drain unless instructed to do so. Instead, follow any specific disposal instructions provided by your healthcare provider or local waste disposal company.
$Name is generally well-tolerated. However, as with any supplement, indigestion may occur. To help manage indigestion, try taking Nebivol-CL Tablet 10's with food to reduce stomach upset, avoid lying down after taking it, stay hydrated by drinking plenty of water, and avoid spicy or fatty foods that can exacerbate indigestion. If your symptoms persist or worsen, seek medical attention.
It is highly recommended to limit or avoid alcohol while taking this medicine. Alcohol can cause your blood pressure to drop too low, making you feel excessively dizzy, lightheaded, or sleepy. Talk to your doctor or pharmacist about safe alcohol limits for you.
If you feel dizzy, sit or lie down immediately until the feeling passes. To prevent this, avoid standing up too quickly from a lying or sitting position. If the dizziness is severe or does not go away, talk to your doctor.
Nebivol-CL Tablet 10's is generally not recommended during pregnancy or while breastfeeding, as it may affect blood flow to the baby. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor to discuss safer alternative treatments.
Nebivol-CL Tablet 10's does not usually affect blood sugar levels directly, but the beta-blocker component (nebivolol) can hide the physical symptoms of low blood sugar, such as a fast heart rate or shakiness. If you have diabetes, check your blood sugar regularly and talk to your doctor.
Nebivol-CL Tablet 10's starts to lower your blood pressure within a few hours of taking your first dose. However, it may take several weeks of consistent use to see the full benefits and achieve stable blood pressure control. Talk to your doctor if you have concerns about your blood pressure readings.
No, you should not stop taking this medicine even if you feel completely well. High blood pressure often has no symptoms, and stopping the medicine abruptly can cause your blood pressure to rise rapidly, increasing your risk of a heart attack or stroke. Always consult your doctor before making any changes.
Ankle swelling can occur because cilnidipine relaxes and widens the small blood vessels in your lower limbs, which can occasionally cause fluid to pool in your ankles. If you experience severe or painful swelling, talk to your doctor.
Some beta-blockers can occasionally cause sexual side effects, such as erectile dysfunction, in a small number of people. However, nebivolol is generally known to have a lower risk of these side effects compared to older beta-blockers due to its nitric oxide-releasing properties. If you experience any persistent side effects, talk to your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. National Center for Biotechnology Information (NCBI). Pmc2015014 Scientific Research Publication. Bethesda, MD: NLM; 2025. [Accessed on 02 Jun. 2026]Check here
  2. National Center for Biotechnology Information (NCBI). Pmc6477925 Scientific Research Publication. Bethesda, MD: NLM; 2025. [Accessed on 02 Jun. 2026]Check here
  3. Shivani Priyadarshni, Bryan H. Curry. Nebivolol. NIH. National Library of Medicine, National center for biotechnology information. November 2021. [Accessed on 8th June 2022]Check here
  4. Robert Weiss. Nebivolol: A Novel Beta-Blocker with Nitric Oxide-Induced Vasodilatation. NIH. National Library of Medicine, National center for biotechnology information. [Revised in September 2006] [Accessed on 8th June 2022]Check here
  5. Torrent Pharmaceuticals Ltd. Cilnidipine + Nebivolol Tablets [Internet]. Ahmedabad: Torrent Pharmaceuticals Ltd.; 2024 [Accessed on 2025 Jun 23]Check here
  6. Central Drugs Standard Control Organisation. Drugs. [Internet]. New Delhi: Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India; [Accessed on 2025 Jun 23]Check here

Country of origin

India

Manufacturer/Marketer address

M-17, Pharma Tower, Basement & Ground Floor, Badli Industrial Area, New Delhi 110 042
Other Info - NEB0400
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