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compositionComposition:HYDROCHLOROTHIAZIDE-12.5MG+NEBIVOLOL-5MG
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Prescription Medicine
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Nebiwin H Tablet is used to treat high blood pressure. It effectively lowers elevated blood pressure and supports better heart function. By maintaining normal blood pressure, this combination helps reduce the risk of heart attack, stroke, heart failure, and kidney complications associated with long-term hypertension.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

HYDROCHLOROTHIAZIDE-12.5MG+NEBIVOLOL-5MG

Manufacturer/Marketer :

Docwin Healthcare

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Nebiwin H Tablet

Nebiwin H Tablet is a prescription oral tablet primarily used to treat high blood pressure (hypertension). By lowering elevated blood pressure, this medication helps protect vital organs like your heart, kidneys, and brain from long-term damage. Managing high blood pressure effectively reduces your risk of experiencing serious complications like strokes or heart attacks.

To achieve the best results, it is important to take Nebiwin H Tablet consistently at the same time every day as directed by your healthcare provider. You can take this medication with or without food, but keeping your routine uniform helps maintain stable medicine levels in your body. Combining this medication with a heart-healthy diet low in sodium and regular physical activity can significantly improve your blood pressure control.

While taking Nebiwin H Tablet , you may experience some common, mild side effects such as mild dizziness, headache, or feeling unusually tired. However, you should contact your doctor immediately if you experience serious symptoms like an unusually slow heartbeat, severe dizziness, chest pain, or signs of high fluid loss such as extreme thirst or dry mouth.

Do not take this if you have severe liver damage, severe kidney disease, a very slow heart rate, or serious heart block conditions. Before starting this medicine, talk to your doctor if you have a history of diabetes, asthma, gout, thyroid disorders, or blood circulation problems. Your doctor will help determine if this medication is the safest option for your specific health profile.

Certain medicines, such as specific pain relievers or lithium, can interact with Nebiwin H Tablet and affect how it works or increase side effects. You should also limit alcohol consumption and discuss smoking with your doctor, as both can interfere with blood pressure control. If you are pregnant, breastfeeding, or are an elderly individual, consult your healthcare provider to discuss special precautions.

Uses of Nebiwin H Tablet

Your doctor may prescribe Nebiwin H Tablet for the following established clinical uses:

  • High Blood Pressure (Hypertension): Helps lower elevated blood pressure when single-agent treatments are not sufficient, reducing the strain on your cardiovascular system.
  • Reducing Cardiovascular Risk: Lowering long-term high blood pressure helps decrease your chances of suffering from future strokes, heart attacks, or kidney failure.

Key Benefits

Nebiwin H Tablet helps manage high blood pressure effectively while supporting long-term cardiovascular health. By combining two blood pressure-lowering medicines in a single tablet, it provides comprehensive blood pressure control and helps reduce the risk of hypertension-related complications.

  • Helps Maintain Healthy Blood Pressure Levels: By lowering and controlling blood pressure, Nebiwin H Tablet helps reduce strain on the heart and blood vessels, supporting better cardiovascular function and overall health.
  • Supports Protection of Vital Organs: Consistent blood pressure control with Nebiwin H Tablet helps protect important organs such as the heart, kidneys, brain, and blood vessels from damage associated with uncontrolled hypertension.
  • Provides Convenient Dual-Action Treatment: By combining two active ingredients in a single tablet, Nebiwin H Tablet offers effective blood pressure management with a simplified treatment regimen. This convenience may help improve adherence to therapy and support long-term treatment success.

Directions for Use

  • It can be taken with or without food as advised by a doctor.
  • Adhere to your doctor's guidance regarding the dosage and timing of this medication for optimal effectiveness.
  • Swallow Nebiwin H Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Nebiwin H Tablet Works

Nebiwin H Tablet works by utilising two distinct actions in the body to lower blood pressure more effectively than either could alone. The first active component, nebivolol, is a selective beta-blocker. It works by targeting specific receptors in your heart and blood vessels. This action slows down your heart rate slightly and allows the heart to pump blood more efficiently and with less effort, which naturally lowers the pressure in your blood vessels. The second active component, hydrochlorothiazide, is a diuretic, often referred to as a 'water pill'. It acts on your kidneys to help your body eliminate excess salt and water through your urine. Reducing the total amount of fluid circulating through your blood vessels lowers the overall pressure against the artery walls. Together, these two actions provide comprehensive, 24-hour blood pressure control.
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Alcohol

Unsafe

You are recommended not to consume alcohol and Nebiwin H Tablet to avoid unpleasant side effects like drowsiness and dizziness.

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Pregnancy

Unsafe

Nebiwin H Tablet is not recommended during pregnancy. Nebiwin H Tablet contains hydrochlorothiazide that crosses the placenta. This may cause fetal damage and can affect the unborn baby (fetus).

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Breast Feeding

Unsafe

Tell your doctor if you are breast-feeding or about to start breast-feeding. Nebiwin H Tablet is not recommended for mothers who are breast-feeding.

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Driving

Caution

Nebiwin H Tablet usually causes drowsiness and dizziness, affecting your ability to drive or operate machinery.

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Liver

Caution

Nebiwin H Tablet to be taken with caution, especially if you have a history of liver disease. Your doctor may adjust your dose depending on your current liver conditions.

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Kidney

Caution

Nebiwin H Tablet to be taken with caution, especially if you have a history of Kidney disease. Your doctor may adjust your dose depending on your current kidney conditions.

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Children

Unsafe

Nebiwin H Tablet is not recommended for children younger than 18 years of age.

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Heart

Caution

Nebiwin H Tablet should be taken with caution in patients with heart problems. Please inform your doctor if you have any pre-existing heart problems before using Nebiwin H Tablet .

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Geriatrics

Caution

Nebiwin H Tablet should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using Nebiwin H Tablet .

What if I have taken an overdose of Nebiwin H Tablet

If you suspect an overdose, seek immediate medical attention or contact your local poison control centre. Symptoms of an overdose can include severe dizziness, a dangerously slow heartbeat, or fainting.

Diet & Lifestyle Advise

To support your medical treatment and achieve the best cardiovascular outcomes, consider incorporating these practical, evidence-based habits into your routine:

  • Reduce Sodium Intake: Limit your daily intake of salt by avoiding processed foods, canned soups, and adding extra salt at the table, as sodium directly raises blood pressure.
  • Eat Potassium-Rich Foods: Because diuretics can cause your body to lose potassium, discuss with your doctor whether you should include foods like bananas, spinach, and sweet potatoes in your diet.
  • Stay Safely Hydrated: Drink adequate water throughout the day, but avoid sudden, excessive fluid intake unless advised otherwise by your physician.
  • Incorporate Light Exercise: Aim for at least 30 minutes of moderate physical activity, such as brisk walking, on most days of the week, as approved by your doctor.
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How Soon It Starts Working

The time required for Nebiwin H Tablet to start to work: The time required for Nebiwin H Tablet to start to work is 2 hours after administration. 

The time for which the effects of Nebiwin H Tablet last: The effect of Nebiwin H Tablet lasts for 12 hours.

What if you forget to take Nebiwin H Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose entirely and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.

Storage

•Store Nebiwin H Tablet at room temperature, ideally between 20°C and 25°C (68°F to 77°F). •Keep the tablets in their original packaging to protect them from direct light and moisture. Do not store them in humid environments like bathroom cabinets.

Drug Warnings

  • Stand up slowly: To prevent dizziness or fainting, take your time when moving from a sitting or lying position to a standing one.
  • Monitor blood sugar: If you have diabetes, check your blood glucose regularly. This medication can sometimes hide the physical signs of low blood sugar, such as a rapid heart rate.
  • Protect your skin: This medicine can increase your sensitivity to sunlight. Wear protective clothing, apply sunscreen daily, and avoid tanning beds to prevent painful sunburns.
  • Do not stop abruptly: Stopping this medicine suddenly can cause your blood pressure to spike dangerously. Consult your doctor if you need to gradually decrease your dose.
  • Keep your medical appointments: Regular check-ups are necessary so your doctor can monitor your blood pressure and run routine blood tests to check your kidney function and electrolyte levels.

Drug-Drug Interactions

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Drug-Drug Interactions

  • Other blood pressure lowering medicines: Combining these can cause your blood pressure to drop too low, resulting in severe dizziness or fainting.
  • NSAIDs (like ibuprofen or naproxen): These pain relievers can reduce the blood-pressure-lowering effectiveness of Nebiwin H Tablet and increase the risk of kidney damage.
  • Lithium: This medication can reduce the clearance of lithium from your body, significantly increasing the risk of lithium toxicity.
  • Diabetes medications: Your doctor may need to adjust your insulin or oral diabetes medications, as Nebiwin H Tablet can alter blood glucose levels.

Drug-Food Interactions

  • Alcohol: Avoid or severely limit alcohol, as it can compound the blood-pressure-lowering effect of Nebiwin H Tablet , causing severe dizziness and drowsiness.

Drug-Disease Interactions

  • Severe Kidney or Liver Disease: Do not take this medication if you have severe kidney failure or liver damage, as it can worsen these conditions.
  • Asthma or COPD: This medicine should be used with caution if you have chronic airway diseases, as beta-blockers can sometimes trigger breathing difficulties.
  • Gout: This medicine can increase uric acid levels in the blood, which may trigger painful gout attacks in susceptible individuals.
Nebivolol + HydrochlorothiazideLithium
Severe
Nebivolol + HydrochlorothiazideArsenic trioxide
Severe

Drug-Drug Interactions

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Nebivolol + HydrochlorothiazideLithium
Severe
How does the drug interact with Nebiwin H Tablet:
Coadministration of Lithium and Hydrochlorothiazide can increase the effects of lithium.

How to manage the interaction:
Taking Lithium and Hydrochlorothiazide together can result in an interaction, but it can be taken if advised by a doctor. However, if you experience any symptoms like loose stools, vomiting, drowsiness, shaking of hands and legs, thirst, increased urination, lack of coordination, or muscle weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Nebivolol + HydrochlorothiazideArsenic trioxide
Severe
How does the drug interact with Nebiwin H Tablet:
Co-administration of Arsenic trioxide and Hydrochlorothiazide can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Arsenic trioxide and Hydrochlorothiazide together is avoided as it can result in an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, fast heartbeats, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, nausea, or vomiting. consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Nebivolol + HydrochlorothiazideFingolimod
Severe
How does the drug interact with Nebiwin H Tablet:
Taking Fingolimod and Nebivolol can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Fingolimod and Nebivolol together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, shortness of breath, chest pain, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Nebivolol + HydrochlorothiazideZiprasidone
Severe
How does the drug interact with Nebiwin H Tablet:
Taking Ziprasidone and Hydrochlorothiazide can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Ziprasidone and Hydrochlorothiazide together can result in an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
Nebivolol + HydrochlorothiazideRitodrine
Severe
How does the drug interact with Nebiwin H Tablet:
Coadministration of Nebivolol and Ritodrine may decrease the effect of Nebivolol. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Nebivolol and Ritodrine together can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
Nebivolol + HydrochlorothiazideSaquinavir
Severe
How does the drug interact with Nebiwin H Tablet:
Using saquinavir together with nebivolol can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking saquinavir together with nebivolol can result in an interaction, it can be taken if a doctor has advised it. However, if you experience dizziness, lightheadedness, fainting, slow pulse, irregular heartbeat, contact a doctor. Do not discontinue any medications without a doctor's advice.
Nebivolol + HydrochlorothiazideDisopyramide
Severe
How does the drug interact with Nebiwin H Tablet:
Taking Disopyramide and Nebivolol can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Disopyramide and Nebivolol together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, shortness of breath, chest pain, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Nebivolol + HydrochlorothiazideAminophylline
Severe
How does the drug interact with Nebiwin H Tablet:
Using nebivolol together with aminophylline can make nebivolol less effective and increase the effects of aminophylline.

How to manage the interaction:
Although Nebiwin H Tablet and Aminophylline can cause an interaction, it can be taken if a doctor prescribes it. Consult a doctor if you experience nausea, vomiting, insomnia, tremors, restlessness, uneven heartbeats, or difficulty breathing. Do not stop using any medications without talking to a doctor.
Nebivolol + HydrochlorothiazideClonidine
Severe
How does the drug interact with Nebiwin H Tablet:
Co-administration of clonidine and nebivolol together may decrease blood pressure and slow the heart rate.

How to manage the interaction:
Taking clonidine and nebivolol together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience slow heartbeat, headaches, dizziness, or feeling like you might pass out contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Nebivolol + HydrochlorothiazideDolasetron
Severe
How does the drug interact with Nebiwin H Tablet:
Taking Dolasetron and Nebivolol can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Dolasetron and Nebivolol together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, shortness of breath, chest pain, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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HYDROCHLOROTHIAZIDE-12.5MG+NEBIVOLOL-5MGPotassium rich foods, Calcium rich foods
Moderate

Drug-Food Interactions

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HYDROCHLOROTHIAZIDE-12.5MG+NEBIVOLOL-5MGPotassium rich foods, Calcium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt, Tofu Set With Calcium, Ragi, Seasame Seeds, Kale, Milk, Almonds, Bok Choy, Calcium-Fortified Soy Milk, Cheese

How to manage the interaction:
Consumption of Nebiwin H Tablet with calcium rich food may decrease the effectiveness of Hydrochlorothiazide. Increase consumption of potassium-rich foods with Nebiwin H Tablet may cause potassium depletion (low potassium level). Avoid consumption of potassium, calcium rich foods while being treated with Nebiwin H Tablet.

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

FAQs

Nebiwin H Tablet is used to treat hypertension (high blood pressure) and reduce the risk of stroke in patients with high blood pressure.
Nebiwin H Tablet contains nebivolol and hydrochlorothiazide. Nebivolol is a beta blocker that works on the heart to lower heart rate and make the heart more efficient at pumping blood throughout the body. The diuretic hydrochlorothiazide lowers blood pressure by removing excess water and electrolytes from the body. It also relaxes blood vessels and improves blood flow over time.
Nebiwin H Tablet can be safely taken as long as your doctor has prescribed it. Conditions such as high blood pressure are life-long, and one should not abruptly discontinue them without discussing them with a doctor.
If you have missed a dose of Nebiwin H Tablet , you are advised to take it as soon as you remember. However, try not to miss a dose in the first place. If it is time for you to take your next dose, do not take both doses together. Take only one dose; taking a double dose of Nebiwin H Tablet will lead to low blood pressure.
Yes, Nebiwin H Tablet can cause dizziness. Avoid driving or operating any heavy machinery while taking Nebiwin H Tablet . In case you feel dizzy or lightheaded, rest for some time until you feel better.
No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending on your current blood pressure readings, your doctor may lower your medicine dosage and not recommend discontinuing it.
The best time to take Nebiwin H Tablet is morning or evening as advised by the doctor based on your medical condition.
Nebiwin H Tablet can be taken with food or without food as recommended by the doctor.
Nebiwin H Tablet consists of hydrochlorothiazide and nebivolol. Hydrochlorothiazide is a thiazide diuretic and nebivolol is a beta blocker. This medication is used for the treatment of hypertension (high blood pressure) and reduces the risk of stroke in patients with high blood pressure.
Nebiwin H Tablet should be taken orally. Swallow the medicine as a whole with water, do not crush, break or chew it.
The side effects of Nebiwin H Tablet include constipation, diarrhoea, nausea, fatigue, headache, dizziness, decreased potassium level in the blood, altered blood lipid level, increased blood uric acid, increased calcium level in blood, breathlessness, swelling of hands & feet, paraesthesia (burning sensation of the skin), and decreased magnesium level in the blood. Consult the doctor if any of these side effects persist or worsen.
You should be cautious while taking Nebiwin H Tablet if you have kidney disease, liver disease, asthma, diabetes, eye problem (glaucoma), increased uric acid level (gout), hyperlipidaemia (increased lipid level) or hyperthyroidism (increased thyroid level). Consult the doctor before taking Nebiwin H Tablet if you have any of these health conditions.
Consult the doctor before taking other medications with Nebiwin H Tablet , particularly diuretics, blood pressure-lowering medications (amiodarone, clonidine, diltiazem, amlodipine, digoxin, disopyramide), antispasmodic medications (baclofen), medications for mental illness (amisulpiride, haloperidol, chlorpromazine), depression medications (amitriptyline, paroxetine, fluoxetine), anti-cancer medications (cyclophosphamide, methotrexate, fluorouracil), mood stabilizers (lithium), angina medications (bepridil), blood sugar-lowering medications (insulin, metformin), gout medications (allopurinol, sulfinpyrazone, probenecid), and medications used to treat low blood pressure medications (noradrenaline).
Nebiwin H Tablet should be stored in a cool and dry place away from sunlight. Keep it out of sight and reach of children.
No, this medication is generally not recommended during pregnancy as it may cause harm to the developing baby. If you suspect you are pregnant or are planning to become pregnant, talk to your doctor immediately about safer treatment options.
Yes, one of the active components of this medicine is a diuretic, which helps your body get rid of excess fluid by increasing urine output. To avoid waking up during the night to use the bathroom, it is usually best to take your dose in the morning. Talk to your doctor if this becomes problematic.
It is highly recommended to avoid or limit alcohol while taking this medicine. Alcohol can lower your blood pressure further, increasing the risk of severe dizziness, drowsiness, and fainting. Talk to your doctor or pharmacist for personalised advice.
This medication can alter your blood sugar levels and may also mask physical warning signs of low blood sugar, such as a fast heartbeat. If you have diabetes, you should monitor your blood sugar closely and talk to your doctor about managing your condition.
Because this medicine contains a diuretic that can lower potassium levels in your blood, your doctor will routinely monitor your blood work. You should not start taking potassium supplements unless your doctor explicitly tells you to do so. Talk to your doctor if you have concerns.
Yes, this medication can make your skin more sensitive to sunlight, which increases your risk of sunburn and skin reactions. It is important to wear high-SPF sunscreen, wear protective clothing, and limit your direct sun exposure while taking this medicine. Talk to your doctor if you experience any unusual skin changes.

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Country of origin

India

Manufacturer/Marketer address

305/A, Panlee Complex, Mithakhali Cross Roads, Navrangpura, Ahmedabad - 380006
Other Info - NEB0324
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