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  3. Nebzmart-GF Combipack Smartule ( 5 x 1 ml )

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Nebzmart-GF Combipack Smartule ( 5 x 1 ml ), Pack of 1 CAPSULE
Nebzmart-GF Combipack Smartule ( 5 x 1 ml ), Pack of 1 CAPSULE
Nebzmart-GF Combipack Smartule ( 5 x 1 ml ), Pack of 1 CAPSULE
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Extra 15% Off with Bank Offers

Composition :

ARFORMOTEROL-15MCG + GLYCOPYRRONIUM-25MCG

Manufacturer/Marketer :

Glenmark Pharmaceuticals Ltd

Consume Type :

INHALATION

Return Policy :

Not Returnable

Expires on or after :

About Nebzmart-GF Combipack Smartule ( 5 x 1 ml )

Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) belongs to the group of medicines called bronchodilators indicated for long-term, maintenance treatment of Chronic Obstructive Pulmonary Disease (COPD). COPD is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the bronchial tube lining). 
 
Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) is a combination of two medicines, namely: Arformoterol (long-acting beta2-adrenergic agonist) and Glycopyrronium (anti-cholinergic). Arformoterol prevents tightening of the muscles in the airways, making it easier for the air to get in and out of the lungs. Glycopyrronium decreases the secretions in the airways. Together, Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) provides relief from COPD.
 
You are advised to use Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as headache, nausea, dry mouth, chest pain, muscle cramps, and dizziness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Do not stop using Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) on your own as it might cause worsening of symptoms. Consult your doctor before using Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) if you are pregnant or breastfeeding. Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) may cause dizziness, so drive with caution. Avoid consuming alcohol as it might cause increased dizziness. Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) is not recommended for children below 18years as the safety and effectiveness have not been established. Keep your doctor informed about your health condition and the medicines you are taking to avoid unpleasant side effects.

Uses of Nebzmart-GF Combipack Smartule ( 5 x 1 ml )

Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) is used in the treatment of Chronic Obstructive Pulmonary Disease (COPD). The detailed uses of Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) are as follows:

  • It is used to treat Chronic Obstructive Pulmonary Disease (COPD), which helps to enhance lung function and alleviate dyspnea.
  • Treatment for Prevention: Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) can be used as a maintenance treatment to help patients better regulate their respiratory condition over the long term by preventing flare-ups of COPD or asthma attacks.
  • Improving Lung Function: By lowering airway inflammation, Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) aids in improving lung function and can increase physical activity tolerance in people with long-term respiratory conditions.
  • Symptomatic Relief: This medication offers prompt alleviation of respiratory disease symptoms such coughing, wheezing, and dyspnea.

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Directions for Use

  • Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) can be taken with or without food.
  • Check the instruction leaflet before use.
  • Open the smartule by twisting off the cap. Squeeze the content into the reservoir of the nebulizing chamber. 
  • Discard the smartule after use. 
  • Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) should be used with a nebuliser only in the dose and duration prescribed by a doctor. It is not to be injected or administered orally.
  • Any invisible damage caused during transit or storage may cause contamination. Do not use the smartule if the suspension is discolored, has any leaks upon squeezing or contains visible black particles.

Medicinal Benefits

Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) is a combination of two medicines, namely: Arformoterol and Glycopyrronium. Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) belongs to the group of medicines called bronchodilators used to treat Chronic Obstructive Pulmonary Disease (COPD). Arformoterol is a long-acting beta-agonist that prevents tightening of the muscles in the airways, making it easier for the air to get in and out of the lungs. Glycopyrronium is an anti-cholinergic that decreases the secretions in the airways. Together, Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) provides relief from COPD.

How Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) Works

Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) is a combination of two medicines, namely: Arformoterol (long-acting beta2-adrenergic agonist) and Glycopyrronium (anti-cholinergic). Arformoterol prevents tightening of the muscles in the airways, making it easier for the air to get in and out of the lungs. Glycopyrronium decreases the secretions in the airways. Together, Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) provides relief from COPD.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Nebzmart-GF Combipack Smartule ( 5 x 1 ml )
  • Focus on eating nutrient-rich foods such as citrus fruits, spinach, ginger, garlic, turmeric, and fermented foods to improve immunity and general health.
  • Drink plenty of water to stay hydrated, and think about taking probiotics, zinc, vitamin C, and vitamin D supplements.
  • Adopt healthful practices such as leading a balanced lifestyle and remaining at home when necessary.
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.
Here are the steps to manage the medication-triggered Sinusitis (Sinus infection or Inflammation Of Sinuses):
  • Consult your doctor if you experience symptoms of sinusitis, such as nasal congestion, facial pain, or headaches, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your sinusitis symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • If your doctor advises, you can use nasal decongestants or saline nasal sprays to help relieve nasal congestion and sinus pressure.
  • To help your body recover, get plenty of rest, stay hydrated, and engage in stress-reducing activities. If your symptoms persist or worsen, consult your doctor for further guidance.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.

What if I have taken an overdose of Nebzmart-GF Combipack Smartule ( 5 x 1 ml )

Do not use Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) in more doses or more often than prescribed. If you have any unusual signs or symptoms, please consult a doctor immediately.

Drug Warnings

Do not use Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) if you are allergic to any of its contents. Inform your doctor if you have asthma, heart problems, seizures/epilepsy, thyroid gland problems, diabetes, narrow-angle glaucoma, kidney problems, severe liver problems, if you have any difficulty in passing urine or if you are taking any medicines for lung diseases. Consult your doctor before using Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) if you are pregnant or breastfeeding. Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) may cause dizziness, so drive with caution. Avoid consuming alcohol as it might cause increased dizziness. Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) is not recommended for children below 18years as the safety and effectiveness have not been established. 

Drug-Drug Interactions

verifiedApollotooltip
GlycopyrrolatePotassium citrate
Critical
GlycopyrrolatePotassium chloride
Critical

Drug-Drug Interactions

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GlycopyrrolatePotassium citrate
Critical
How does the drug interact with Nebzmart-GF Combipack Smartule ( 5 x 1 ml ):
Co-administration of Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) with Potassium citrate can increase the risk or severity of ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
Taking Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) with Potassium citrate together is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
GlycopyrrolatePotassium chloride
Critical
How does the drug interact with Nebzmart-GF Combipack Smartule ( 5 x 1 ml ):
Taking Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) with Potassium chloride can increase the risk or severity of ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
Taking Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) with Potassium chloride together is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
GlycopyrrolateTopiramate
Severe
How does the drug interact with Nebzmart-GF Combipack Smartule ( 5 x 1 ml ):
Coadministration of Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) with Topiramate can increase the risk or severity of side effects like increased body temperature and decreased sweating.

How to manage the interaction:
Taking Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) with Topiramate together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience drowsiness, dizziness, lightheadedness, fever, chills, or decreased sweating, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
GlycopyrrolateZonisamide
Severe
How does the drug interact with Nebzmart-GF Combipack Smartule ( 5 x 1 ml ):
Coadministration of Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) with Zonisamide can increase the risk or severity of Zonisamide side effects like increased body temperature and decreased sweating especially in warm weather.

How to manage the interaction:
Taking Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) with Zonisamide together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience dizziness, drowsiness, fatigue, increased heart rate, fever, or excessive sweating, contact a doctor immediately. Make sure to hydrate yourself during warm weather or after exercise. Do not discontinue any medications without consulting a doctor.
FormoterolEpinephrine
Severe
How does the drug interact with Nebzmart-GF Combipack Smartule ( 5 x 1 ml ):
Using epinephrine together with Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) may increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) and Epinephrine together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
FormoterolLabetalol
Severe
How does the drug interact with Nebzmart-GF Combipack Smartule ( 5 x 1 ml ):
Co-administration of labetalol and Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) together could decrease the effects of both medications.

How to manage the interaction:
Although taking Labetalol and Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
FormoterolSotalol
Severe
How does the drug interact with Nebzmart-GF Combipack Smartule ( 5 x 1 ml ):
Taking sotalol with Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) could reduce the benefits of both medications because they have opposite effects on the body.

How to manage the interaction:
Although there is an interaction between Sotalol and Nebzmart-GF Combipack Smartule ( 5 x 1 ml ), they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
FormoterolRibociclib
Severe
How does the drug interact with Nebzmart-GF Combipack Smartule ( 5 x 1 ml ):
Taking ribociclib together with Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) can increase the risk of an irregular heart rhythm

How to manage the interaction:
Co-administration of Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) with Ribociclib can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath, contact your doctor right away. Do not stop using any medications without first talking to your doctor.
FormoterolCarteolol
Severe
How does the drug interact with Nebzmart-GF Combipack Smartule ( 5 x 1 ml ):
Taking carteolol with Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) can reduce the effects of both drugs.

How to manage the interaction:
Although there is an interaction between Carteolol and Nebzmart-GF Combipack Smartule ( 5 x 1 ml ), they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
FormoterolMetipranolol
Severe
How does the drug interact with Nebzmart-GF Combipack Smartule ( 5 x 1 ml ):
Using Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) together with metipranolol can reduce the effects of both medications.

How to manage the interaction:
Although there is an interaction between Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) and metipranolol, they can be taken together if prescribed by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to strengthen your breathing muscles and boost your immune system.

  • Avoid foods such as cabbage, beans, garlic, onions, shrimp, pickled food, dried fruits, fried foods, carbonated drinks, wine, bottled lemon and lime juice as it may worsen symptoms.

  • Do meditation, deep breathing, regular exercise and try progressive muscle relaxation techniques to get relief from stress and reduce the risk of an attack.

  • Quit smoking as it may reduce the effectiveness of Nebzmart-GF Combipack Smartule ( 5 x 1 ml ), irritate the lungs and worsen breathing problems.

  • Learn breathing exercises like pursed-lip breathing. It helps provide relief from COPD.

Habit Forming

No

Therapeutic Class

BRONCHODILATOR
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Alcohol

Caution

You are advised not to consume alcohol while using Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) as it might cause increased dizziness.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before using Nebzmart-GF Combipack Smartule ( 5 x 1 ml ); your doctor will decide whether Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) can be used by breastfeeding mothers or not.

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Driving

Caution

Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) may cause dizziness. Drive or operate machinery only if you are alert.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor before using Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) if you have liver impairment/liver disease or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor before using Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) if you have kidney impairment/kidney disease or any concerns regarding this.

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Children

Unsafe

Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) is not recommended for children below 18years as the safety and effectiveness have not been established.

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Heart

Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) should be used with caution in patients with heart problems. Please inform your doctor if you have any pre-existing heart problems.

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Geriatrics

Consult your doctor

Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) should be used in elderly patients only when prescribed by a doctor. If you have any concerns about using Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) in older adults, please consult your doctor.

FAQs

Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) belongs to the group of medicines called bronchodilators indicated for long-term, maintenance treatment of Chronic Obstructive Pulmonary Disease (COPD).

Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) contains Arformoterol and Glycopyrronium. Arformoterol relaxes and widens the openings in the airways, making it easier for the air to get in and out of the lungs. Glycopyrronium decreases the secretions in the airways. Together, Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) provides relief from COPD.

Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) is indicated for the maintenance treatment for COPD. It does not treat a sudden attack of wheezing or breathlessness. Use a rescue inhaler to treat sudden breathing problems.

Dry mouth could be a side-effect of Nebzmart-GF Combipack Smartule ( 5 x 1 ml ). Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, and drinking water regularly can help cope with dry mouth.

Do not stop using Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) on your own as it might cause worsening of symptoms. To treat your condition effectually, continue using Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) for as long as your doctor has prescribed it. Talk to your doctor if your breathing problems, wheezing, or cough do not improve or worsen.

Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) is not indicated for the treatment of asthma as the safety and effectiveness of Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) in patients with asthma have not been established. Consult your doctor if you have asthma.

Consult your doctor before using Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) if you are diabetic, as it might sometimes raise blood sugar levels. Regular monitoring of blood glucose levels whilst using Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) is advised.

No, avoid smoke while taking Nebzmart-GF Combipack Smartule ( 5 x 1 ml ). Smoking irritates the lungs which will worsen the condition. If you find any difficulties in quitting smoke, take advice from your doctor for alternative remedies or any dose adjustments.

Nebzmart-GF Combipack Smartule ( 5 x 1 ml ) causes side effects such as headache, dizziness, dry mouth, nausea, chest pain, muscle cramps, and anxiety. However, these conditions do not require any medical treatment, they will resolve over time.

Country of origin

India

Manufacturer/Marketer address

Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.
Other Info - NEB0242

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Author Details

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Oct 31, 2025 | 7:29 AM IST

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Reference

  1. https://www.drugs.com/mtm/arformoterol-inhalation.html
  2. https://go.drugbank.com/drugs/DB01274
  3. https://www.drugs.com/mtm/glycopyrrolate-inhalation.html

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