Nemifen P 100/325 Tablet 10'S
MRP ₹60
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About Nemifen P 100/325 Tablet 10'S
Nemifen P 100/325 Tablet 10'S belongs to a class of painkillers called non-steroidal anti-inflammatory drugs (NSAIDs) used to relieve pain in conditions like osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and dysmenorrhea. Besides this, it is also useful for dental pain, muscle pain, back pain, ear pain, and throat pain.
Nemifen P 100/325 Tablet 10'S is composed of two medicines: Nimesulide and Paracetamol. Nemifen P 100/325 Tablet 10'S works by blocking the effect of prostaglandins, a chemical responsible for inducing pain and inflammation in the body. It also lowers the elevated body temperature by promoting heat loss (through sweating), which helps reset the hypothalamic thermostat. Together, Nemifen P 100/325 Tablet 10'S helps relieve pain.
Take Nemifen P 100/325 Tablet 10'S exactly as directed by your doctor. The most common side effects of Nemifen P 100/325 Tablet 10'S are loss of appetite (in case of liver condition), nausea, vomiting, abdominal pain, persistent tiredness or dark/discoloured urine. It is not necessary for everyone to experience the above side effects. In case of any discomfort, speak with your doctor.
Do not take Nemifen P 100/325 Tablet 10'S if you are allergic to painkillers like aspirin, ibuprofen, naproxen or diclofenac. It is not recommended for use in children, people with liver disease, heart disease or gastric ulcers/bleeding problems. Nemifen P 100/325 Tablet 10'S may be associated with a small increase in heart attack risk (myocardial infarction). Avoid alcohol consumption as it may damage your liver and cause increased side effects on taking this medicine. Consult your doctor if your pain, inflammation and fever symptoms do not disappear even after ten days.
Uses of Nemifen P 100/325 Tablet 10'S
Nemifen P 100/325 Tablet 10'S is used to provide pain relief. The detailed uses of Nemifen P 100/325 Tablet 10'S are as follows:
- Pain Relief: Nemifen P 100/325 Tablet 10'S relieves mild to moderate pain, such as headaches, muscle aches, and joint pain.
- Fever Reduction: Nemifen P 100/325 Tablet 10'S helps to reduce fever, relieving discomfort caused by high body temperature.
- Arthritis Management: Nemifen P 100/325 Tablet 10'S is involved in managing arthritis symptoms by reducing pain and inflammation.
- Post-operative Care: Nemifen P 100/325 Tablet 10'S helps to manage post-operative pain, making recovery more comfortable after surgery.
- Chronic Pain Conditions: Nemifen P 100/325 Tablet 10'S provides relief for chronic pain conditions, helping when other treatments may not be enough.
- Respiratory Infection Relief: Nemifen P 100/325 Tablet 10'S is also used to alleviate pain, fever, and inflammation associated with respiratory infection.
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Directions for Use
- Nemifen P 100/325 Tablet 10'S should be taken with food.
- Follow your doctor's instructions on the dosage and timing of this medication.
- Swallow Nemifen P 100/325 Tablet 10'S as a whole with a glass of water.
- Do not crush, break, or chew it.
Medicinal Benefits
Nemifen P 100/325 Tablet 10'S comprises nimesulide and paracetamol, primarily used to treat mild to moderate pain. Nemifen P 100/325 Tablet 10'S is prescribed mainly to treat pain and relieve discomfort caused by conditions like tooth pain, arthritis, period pain and other types of short-term pains. It helps treat pain by blocking the chemical messenger in the brain responsible for causing fever, pain and inflammation. Nimesulide works by blocking the effect of a chemical known as prostaglandin, responsible for inducing pain and inflammation in our body. On the other hand, Paracetamol lowers the elevated body temperature and mild pain by inhibiting prostaglandin synthesis by promoting heat loss (through sweating) that helps reset the hypothalamic thermostat. Paracetamol has the advantage of producing less gastric irritation than other painkillers like aspirin.
How Nemifen P 100/325 Tablet 10'S Works
Storage
- Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
- Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
- Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
- Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
- Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
- Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
- Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
- Drink water or other clear fluids.
- To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
- Include bland foods like rice, toast, crackers, and rice in your diet.
- Avoid lying down immediately after eating as it may cause indigestion or heartburn.
- Avoid acidic and spicy food as it may cause indigestion.
What if I have taken an overdose of Nemifen P 100/325 Tablet 10'S
Drug Warnings
Nemifen P 100/325 Tablet 10'S is contraindicated in patients with a history of hypersensitivity (allergic) reaction to Nemifen P 100/325 Tablet 10'S, paracetamol, nimesulide, or other pain killers. Please inform your doctor before starting Nemifen P 100/325 Tablet 10'S if you have an active stomach ulcer, recent gastrointestinal bleeding, asthma, recent by-pass heart surgery or severe kidney/liver impairment. Nimesulide present in Nemifen P 100/325 Tablet 10'S is known to affect fertility, so if you are planning for pregnancy, contact the doctor. Nemifen P 100/325 Tablet 10'S should be avoided in both pregnant (especially last trimester of pregnancy) and breastfeeding women, as it may pass the milk affecting the baby. Patients with heart diseases and recent stroke (bleeding in the brain) should not take Nemifen P 100/325 Tablet 10'S as a substitute for aspirin. It should not be given to children (below 12 years) with symptoms of fever and chills or suffering from influenza (flu) or chickenpox.
Drug-Drug Interactions
Drug-Drug Interactions
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Co-administration of Atenolol with Nemifen P 100/325 Tab could increase the risk of low blood pressure.
How to manage the interaction:
Although there is a possible interaction between Atenolol and Nemifen P 100/325 Tab, you can take these medicines together if prescribed by a doctor. Consult a doctor if you experience excessive sweating, shortness of breath, palpitations, or chest discomfort. Do not discontinue any medications without consulting a doctor.
Co-administration of ketamine and Nemifen P 100/325 Tab may decrease the effectiveness of Ketamine which could result in a higher blood level.
How to manage the interaction:
Although taking Ketamine and Nemifen P 100/325 Tab together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you're feeling very sleepy or having trouble breathing, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
Co-administration of Mipomersen with Nemifen P 100/325 Tab may increase the risk or severity of liver injury.
How to manage the interaction:
There may be a possibility of interaction between Nemifen P 100/325 Tab and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
Co-administration of Nemifen P 100/325 Tab may decrease the excretion rate of Oxazepam which could result in a higher serum level.
How to manage the interaction:
Although there is a possible interaction between Oxazepam and Nemifen P 100/325 Tab, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
Co-administration of Nemifen P 100/325 Tab and Leflunomide may increase the risk of liver problems.
How to manage the interaction:
Although there is a possible interaction between Nemifen P 100/325 Tab and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Co-administration of Teriflunomide with Nemifen P 100/325 Tab may increase the risk or severity of Liver problems.
How to manage the interaction:
Taking Nemifen P 100/325 Tab with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
Co-administration of Lomitapide and Nemifen P 100/325 Tab may increase the risk of severity of liver injury.
How to manage the interaction:
Although there is a possible interaction between Nemifen P 100/325 Tab and Lomitapide, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
Co-administration of Nemifen P 100/325 Tab and Ketoconazole may increase the risk of liver injury.
How to manage the interaction:
Although there is a possible interaction between Nemifen P 100/325 Tab and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you have joint pain or swelling, fever, chills, unusual bleeding or bruising, skin rash, itching, over-tiredness, nausea, vomiting, loss of appetite, stomach pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor immediately as these may be signs and symptoms of liver damage. Do not discontinue the medication without consulting a doctor.
Co-administration of Nemifen P 100/325 Tab and Valdecoxib may increase the risk or severity of adverse effects.
How to manage the interaction:
Although there is a possible interaction between Nemifen P 100/325 Tab and Valdecoxib, you can take these medicines together if prescribed by a doctor. However, if the side effects worsen, please consult a doctor.
Drug-Food Interactions
Drug-Food Interactions
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Diet & Lifestyle Advise
- Include more glucosamine, chondroitin sulphate, vitamin D, and calcium-enriched supplements. Besides this, turmeric and fish oils can help reduce inflammation in the tissue.
- Please do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching low,, impact aerobic exercises like walking on a treadmill, bike riding and swimming. You can also strengthen your muscles by lifting light weights.
- In chronic arthritis or joint pain conditions, fish like salmon, trout, tuna and sardines. These fishes are enriched with omega-3 fatty acids that minimize chemical cytokines, which ramp up inflammation.
- Your sitting posture is important, especially when you have pain and inflammation. Try to sit as little as possible and only for a short time. Long-term immobility is harmful in conditions like arthritis. Use back support like a rolled-up towel to minimise pain at the back of your spine curve. Keep your knees and hips at a right angle. Besides this, you can also use a footrest if required.
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Alcohol
Caution
Taking Nemifen P 100/325 Tablet 10'S with alcohol may cause dizziness or drowsiness. Besides this, it can also damage your liver if taken for a longer duration. So, avoid or limit the intake of alcoholic beverages with Nemifen P 100/325 Tablet 10'S.
Pregnancy
Unsafe
Use of Nemifen P 100/325 Tablet 10'S during pregnancy is not recommended as taking this medicine during the last 3 months of pregnancy may harm the unborn baby. Consult your doctor for further advice.
Breast Feeding
Unsafe
Use of Nemifen P 100/325 Tablet 10'S during breastfeeding is not recommended as it may pass through the milk and harm the baby. Consult your doctor for further advice.
Driving
Caution
After taking Nemifen P 100/325 Tablet 10'S, you may notice dizziness, sleepiness, drowsiness. So, you should stop taking Nemifen P 100/325 Tablet 10'S and contact your doctor.
Liver
Caution
Nemifen P 100/325 Tablet 10'S to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.
Kidney
Caution
Nemifen P 100/325 Tablet 10'S to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.
Children
Caution
Nemifen P 100/325 Tablet 10'S is contraindicated in children below 20 kg body weight or younger than 6 years of age. It may cause kidney problems in children and adolescents who are dehydrated.
Heart
Nemifen P 100/325 Tablet 10'S should be avoided in cardiac patients as it can lead to serious cardiavascular risks
Geriatrics
Caution
Nemifen P 100/325 Tablet 10'S should be given with caution in geriatrics due to increased risk of side effects. If you have any concerns about using Nemifen P 100/325 Tablet 10'S, please consult a doctor.
FAQs
Nemifen P 100/325 Tablet 10'S is used to relieve pain in conditions like osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and dysmenorrhea. Besides this, it is also useful for dental pain, muscle pain, back pain, ear pain, and throat pain.
Nemifen P 100/325 Tablet 10'S works by blocking the effect of prostaglandins, a chemical responsible for inducing pain and inflammation in the body. It also lowers the elevated body temperature by promoting heat loss (through sweating), which helps reset the hypothalamic thermostat. Together, Nemifen P 100/325 Tablet 10'S helps relieve pain.
No, Nemifen P 100/325 Tablet 10'S is not indicated for stomach pain. If you have stomach pain post-ingestion, it may be a sign of stomach ulcer or gastric bleeding. Do not take Nemifen P 100/325 Tablet 10'S in this condition. It is better to inform your doctor in case of stomach pain post-ingestion of this medication.
No, Nemifen P 100/325 Tablet 10'S should not be taken as a long-term medication as it may lead to stomach ulcers/bleeding and kidney problems. For best results, take it in the doses and duration advised by your doctor.
Yes, Nemifen P 100/325 Tablet 10'S should preferably be taken with food to avoid an upset stomach. If taken on an empty stomach, it may cause stomach irritation and an upset stomach.
You should not take Nemifen P 100/325 Tablet 10'S if you have a history of peptic ulceration, a history of gastrointestinal haemorrhage, Crohn's disease or ulcerative colitis.
No, Nemifen P 100/325 Tablet 10'S should not be taken if you plan to get pregnant, as it contains nimesulide, which may cause birth defects. So, before starting Nemifen P 100/325 Tablet 10'S, please consult your doctor if you are pregnant or planning pregnancy.
Though Nemifen P 100/325 Tablet 10'S may be used for tooth pain, it should not be used in children unless advised by the doctor. Please consult the doctor before using Nemifen P 100/325 Tablet 10'S in children; the doctor will prescribe appropriate medicine based on the child’s condition.
Nemifen P 100/325 Tablet 10'S is a combination medication that belongs to the class of painkillers called non-steroidal anti-inflammatory drugs. It is mainly prescribed to treat pain and relieve discomfort caused by tooth pain, arthritis, period pain, and other types of short-term pain.
As Nemifen P 100/325 Tablet 10'S is indicated for short-term pain relief, it can be discontinued if the pain is relieved. However, it is advised to take Nemifen P 100/325 Tablet 10'S for the prescribed duration to treat your condition effectively.
Taking Nemifen P 100/325 Tablet 10'S may cause nausea and vomiting. If you feel sick, talk to your doctor or pharmacist for help. To cope with nausea and vomiting, take your medicine with food or milk, eat small meals, and stay hydrated. Avoid spicy foods and lying down after taking the medicine. Try ginger products like ginger tea or candies. If your symptoms are severe, ask your doctor for help.
Don't take Nemifen P 100/325 Tablet 10'S if you're allergic to it or other painkillers, have stomach ulcers or bleeding, asthma, recent heart surgery, severe kidney or liver problems. Consult the doctor if you are pregnant or breastfeeding.
Nemifen P 100/325 Tablet 10'S can be taken with vitamin B-complex if prescribed by your doctor. Please consult your doctor if you have any concerns.
Nemifen P 100/325 Tablet 10'S may cause harm to the liver, especially if used for a longer duration or in higher doses. So, do not take a higher dose than the recommended dose of Nemifen P 100/325 Tablet 10'S.
Taking more than the recommended dose of Nemifen P 100/325 Tablet 10'S is dangerous. Overuse of Nemifen P 100/325 Tablet 10'S can harm your liver and kidneys, which can be life-threatening. Always follow the dosage instructions as advised by the doctor.
Nemifen P 100/325 Tablet 10'S should be stored in a cool and dry place away from the sunlight. Keep away from children and pets.
Though Nemifen P 100/325 Tablet 10'S may help lower body temperature, it is primarily used in the treatment of pain relief. Consult your doctor before taking Nemifen P 100/325 Tablet 10'S for fever or if you have any concerns.
Follow your doctor's advice and take the right amount of medicine. Inform your doctor about any health problems, allergies, or other drugs you're taking. Be aware of side effects and take care of yourself. If you're pregnant while on treatment, inform your doctor immediately. Don't take other medications unless instructed by the doctor. Alcohol consumption should be avoided. By following these precautions, you'll benefit most from your medicine and stay safe.
You are recommended to consult your doctor before taking other medications while using Nemifen P 100/325 Tablet 10'S to avoid drug interactions.
If you suspect an overdose of Nemifen P 100/325 Tablet 10'S, seek medical help immediately. Quick action can help prevent serious harm, so don’t wait to seek medical attention.
The common side effects of Nemifen P 100/325 Tablet 10'S include loss of appetite, nausea, vomiting, abdominal pain, persistent tiredness, or dark or discolored urine. Everyone doesn't need to experience the above side effects. In case of any discomfort, speak with your doctor.
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Reference
- https://www.ema.europa.eu/en/documents/referral/nimesulide-article-107-procedures-annex-iii_en.pdf
- https://www.hpra.ie/img/uploaded/swedocuments/7fbc1048-646d-456d-90c0-18da7ec8c42f.pdf
- https://www.medicines.org.uk/emc/files/pil.5164.pdf
- https://www.nhsinform.scot/tests-and-treatments/medicines-and-medical-aids/types-of-medicine/paracetamol
