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compositionComposition:PANCURONIUM-4MG
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Prescription Medicine
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Neocuron 4 mg Injection 2 ml is used to provide muscle relaxation during surgery. It contains Pancuronium which works by blocking nerve impulses and providing muscle relaxation. In some cases, this medicine may cause side effects such as application site reactions and excess saliva. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

PANCURONIUM-4MG

Manufacturer/Marketer :

Neon Laboratories Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Neocuron 4 mg Injection 2 ml

Neocuron 4 mg Injection 2 ml is a prescription muscle relaxant given as an injection into a vein during medical procedures. It is primarily used in hospital settings to temporarily relax your skeletal muscles during major surgeries and to help patients who need assistance from a breathing machine (ventilator).

Because Neocuron 4 mg Injection 2 ml is given only by healthcare professionals in clinical settings, it is not a daily medication that you use at home. There are no daily lifestyle routines required for its use, but following your surgical team's pre-procedure fasting guidelines and maintaining good hydration beforehand is highly important.

While this medicine is highly effective, some people may experience temporary side effects like a faster heart rate or slight changes in blood pressure. It is important to notify your healthcare team immediately if you experience prolonged muscle weakness, breathing difficulties, or signs of an allergic reaction after your procedure.

Before you undergo surgery, talk to your doctor if you have kidney disease, liver damage, myasthenia gravis, or heart problems. Do not take this if you have had a severe allergic reaction to similar muscle-relaxing medications in the past.

This medicine can interact with certain antibiotics and water pills, which may cause the muscle-relaxing effect to last much longer than expected. If you are pregnant, breastfeeding, or an older adult, talk to your doctor or pharmacist about the safety and benefits of using this medicine during your procedure.

Uses of Neocuron 4 mg Injection 2 ml

Doctors typically use Neocuron 4 mg Injection 2 ml in clinical settings for the following reasons:

  • Skeletal muscle relaxation during surgery: It relaxes your body's muscles, which helps surgeons perform operations safely and prevents involuntary muscle movements.
  • Facilitating endotracheal intubation: It relaxes the muscles in your throat and vocal cords, allowing medical staff to easily and safely place a breathing tube before surgery.
  • Assisting with mechanical ventilation: It relaxes the chest wall muscles in critically ill patients, allowing a breathing machine to work smoothly and comfortably.
     

Key Benefits

This medicine provides critical support during major medical procedures, ensuring safety and comfort:

  • Supports safe and precise surgery: By preventing sudden or involuntary muscle twitches, it allows your surgical team to perform delicate procedures with high precision.
  • Improves breathing assistance: For patients in intensive care, it stops the chest muscles from fighting the ventilator, making breathing assistance highly efficient and reducing distress.
  • Reduces throat irritation: Fully relaxing the throat muscles allows the breathing tube to be inserted smoothly, minimising irritation or injury to the airway.
     
Side effects of Neocuron 4 mg Injection 2 ml

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Neocuron 4 mg Injection 2 ml will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Neocuron 4 mg Injection 2 ml Works

Neocuron 4 mg Injection 2 ml contains pancuronium, which belongs to a group of medicines known as non-depolarising neuromuscular blockers. It works by blocking the chemical messages sent from your nerves to your muscles. Normally, your nerves release a chemical called acetylcholine that attaches to muscle cells and tells them to contract or tighten. When injected, Neocuron 4 mg Injection 2 ml temporarily attaches to these muscle receptors and blocks the chemical signals from getting through. Because the muscles do not receive the signal to contract, they remain completely relaxed. This state of temporary relaxation is carefully monitored by your doctor and naturally wears off once the body clears the medicine, or when a reversal medicine is given.
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Alcohol

Caution

It is best to avoid alcohol while taking medication

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Pregnancy

Caution

Avoid taking Neocuron 4 mg Injection 2 ml if you are pregnant unless prescribed by a doctor. Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Neocuron 4 mg Injection 2 ml is not used in breastfeeding mothers. However, consult your doctor before taking Neocuron 4 mg Injection 2 ml; your doctor will decide whether Neocuron 4 mg Injection 2 ml can be taken by breastfeeding mothers or not.

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Driving

Caution

Neocuron 4 mg Injection 2 ml has no or negligible influence on the ability to drive or use machines. Do not drive or operate machines until recovered from the muscle relaxant effects.

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Liver

Caution

Neocuron 4 mg Injection 2 ml should be used with caution in patients with liver diseases. Your doctor may adjust the dose of Neocuron 4 mg Injection 2 ml before prescribing.

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Kidney

Caution

Neocuron 4 mg Injection 2 ml should be used with caution in patients with kidney diseases. Your doctor may adjust the dose of Neocuron 4 mg Injection 2 ml before prescribing.

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Children

Caution

Neocuron 4 mg Injection 2 ml use is not recommended in neonates (children under the age of one month). In the case of necessary treatment in newborn or premature newborns the dose has to be significantly lowered.

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Heart

Caution

Neocuron 4 mg Injection 2 ml should be administered with caution in patients with heart problems. Therefore, please talk to your doctor before receiving Neocuron 4 mg Injection 2 ml.

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Geriatrics

Caution

Neocuron 4 mg Injection 2 ml should be administered with caution in elderly patients due to an increased risk of side effects. If you have any concerns, please consult your doctor.

What if I have taken an overdose of Neocuron 4 mg Injection 2 ml

An overdose of this medicine can cause prolonged muscle relaxation and temporary breathing difficulties. Since it is given in a controlled hospital environment, your medical team will detect any signs of an overdose immediately and can give a reversal medicine or provide breathing support until the effects wear off.

Diet & Lifestyle Advise

To support a safe procedure and a smooth recovery from anaesthesia, keep these tips in mind:

  • Follow your doctor's pre-surgery fasting instructions exactly, including when to stop eating and drinking liquids.
  • Drink plenty of water in the days leading up to your surgery to stay well-hydrated, unless your doctor tells you otherwise.
  • Avoid drinking alcohol and smoking tobacco for at least 24 to 48 hours before your procedure, as they can alter how your body processes anaesthesia.
  • After your procedure, rest quietly and do not attempt any strenuous physical activity until your doctor tells you it is safe.
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How Soon It Starts Working

The time required for Neocuron 4 mg Injection 2 ml to start to work: Neocuron 4 mg Injection 2 ml ideally shows its action within 1 to 2 minutes after administration. The time for which the effects of Neocuron 4 mg Injection 2 ml last: The effect of Neocuron 4 mg Injection 2 ml lasts for 60 to 100 minutes.

What if you forget to take Neocuron 4 mg Injection 2 ml

Because this medication is given only by healthcare professionals during a planned hospital procedure, it is not possible for you to miss a dose.

Storage

•Store Neocuron 4 mg Injection 2 ml in a refrigerator at a controlled temperature between 2°C to 8°C (36°F to 46°F). •Keep the vials in their original carton to protect the liquid from light.
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Keep Refrigerated. Do not freeze.Prepaid payment required.

Drug Warnings

  • Always inform your anesthesiologist if you or any family members have ever had a severe, life-threatening reaction to anaesthesia.
  • Make sure your medical team knows if you have myasthenia gravis, as even small doses of this medicine can cause very long-lasting muscle weakness.
  • Do not attempt to drive, ride a bicycle, or operate heavy machinery for at least 24 hours after receiving this medicine, as your coordination may be temporarily slowed.
  • Ensure your doctor has a complete list of all prescriptions, over-the-counter medicines, and herbal supplements you take before your procedure.

 

Drug-Drug Interactions

verifiedApollotooltip
  • Certain antibiotics (such as aminoglycosides): May increase and prolong the muscle-relaxing effects of Neocuron 4 mg Injection 2 ml, causing unexpected muscle weakness.
  • Water pills (diuretics): Can alter potassium levels in your blood, which may change how effectively this muscle relaxant works.
  • Lithium: May prolong the muscle-relaxing effects, leading to a slower recovery time after surgery.
     

Drug-Drug Interactions

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How does the drug interact with Neocuron 4 mg Injection 2 ml:
Taking Polymyxin b with Neocuron 4 mg Injection 2 ml together can cause breathing problems.

How to manage the interaction:
Taking Polymyxin b with Neocuron 4 mg Injection 2 ml together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any breathing problems, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Neocuron 4 mg Injection 2 ml:
Using Neocuron 4 mg Injection 2 ml with Colistin can increase the risk of developing side effects.

How to manage the interaction:
Although there is a possible interaction between Colistin and Neocuron 4 mg Injection 2 ml, you can take these medicines together if prescribed by your doctor. However, if you experience an upset stomach, rash, dizziness, or fever, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Neocuron 4 mg Injection 2 ml:
Co-administration of Streptomycin with Neocuron 4 mg Injection 2 ml may increase the risk or severity of side effects.

How to manage the interaction:
Co-administration of Neocuron 4 mg Injection 2 ml with Streptomycin can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience flushing, rash, Increased heart rate, sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Neocuron 4 mg Injection 2 ml:
Using Neocuron 4 mg Injection 2 ml with tobramycin can increase the risk of respiratory depression(hypoventilation).

How to manage the interaction:
Although taking Neocuron 4 mg Injection 2 ml and Tobramycin together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Neocuron 4 mg Injection 2 ml:
Co-administration of amikacin with Neocuron 4 mg Injection 2 ml enhances the effects of Neocuron 4 mg Injection 2 ml leading to the risk of breathing disorder.

How to manage the interaction:
Taking Neocuron 4 mg Injection 2 ml with Amikacin together can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without consulting a doctor.
How does the drug interact with Neocuron 4 mg Injection 2 ml:
Coadministration of Neocuron 4 mg Injection 2 ml with Botulinum toxin can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between botulinum toxin and Neocuron 4 mg Injection 2 ml, it can be taken if prescribed by a doctor. However, if you experience muscle weakness or trouble breathing, swallowing, or speaking, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Neocuron 4 mg Injection 2 ml when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[MUSCLE RELAXANTS/SKELETAL MUSCLE RELAXANTS]

FAQs

Neocuron 4 mg Injection 2 ml is used to provide muscle relaxation during surgery.
Neocuron 4 mg Injection 2 ml contains ‘pancuronium’ that relaxes the muscles by blocking nerve impulses. It is used for skeletal muscle relaxation during surgery.
Neocuron 4 mg Injection 2 ml is a cold chain medicine, so it must be stored in the refrigerator between 2-8 degrees Celsius, or its efficiency might get reduced. Do not freeze.
You are advised to inform your doctor before starting treatment with Neocuron 4 mg Injection 2 ml, especially if you are already on medicines like mivacurium (skeletal muscle relaxant), diazepam (a prescription used to control anxiety), steroid medicines, phenytoin (antiepilepsy medication), strong pain-killers (e.g. narcotics), magnesium sulfate (used in the treatment of constipation).
It has been reported that people receiving Neocuron 4 mg Injection 2 ml experienced breathing difficulties, unusually rapid heartbeat, palpitations or irregular heartbeat, problems with vision in rare cases. So, inform your doctor immediately if you notice any of the above signs.
No, Neocuron 4 mg Injection 2 ml is a highly potent injection used only in hospitals during surgery or intensive care. Talk to your doctor or pharmacist about safe oral medicines you can take at home for muscle spasms.
No. Neocuron 4 mg Injection 2 ml only relaxes your muscles. It does not relieve pain or make you unconscious. During surgery, it is given together with general anaesthesia and pain medicines, so you remain asleep and comfortable throughout the procedure. If you have questions about your anaesthesia, speak with your doctor or anaesthesiologist.
This medicine is only used during pregnancy if your doctor decides the benefits clearly outweigh the risks, such as in an emergency surgery. Talk to your doctor if you have concerns about undergoing surgery while pregnant.
Yes, but because your kidneys help remove this medicine from your body, your doctor may need to adjust the dose or monitor you closely to prevent prolonged muscle weakness. Talk to your doctor about your kidney health before your procedure.
This medicine is injected directly into a vein by a trained anaesthesiologist or healthcare provider in a hospital setting. Talk to your doctor if you want to know more about the injection process.
While rare, severe allergic reactions can occur with any medication. Your medical team is fully trained and equipped with rescue medicines to manage any allergic reactions immediately during your procedure. Talk to your doctor if you have a history of drug allergies.

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Country of origin

INDIA

Manufacturer/Marketer address

140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.
Other Info - NEO0065
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