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  3. Nepzil 10mg Tablet

Nepzil 10mg Tablet, Pack of 1 Tablet
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Nepzil 10mg Tablet is used to treat the symptoms of dementia in people with mild and moderately severe Alzheimer's disease. It contains Donepezil, which works by increasing the levels of acetylcholine in the brain, a neurotransmitter involved in memory function. In some cases, it may cause side effects such as diarrhoea, nausea, headache, muscle cramps, and tiredness. Most of these side effects are temporary and gradually resolve over time. However, please consult the doctor if any of these symptoms persist or worsen.

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Composition :

DONEPEZIL-10MG

Manufacturer/Marketer :

Mission Research Laboratories (I) Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Nepzil 10mg Tablet

Nepzil 10mg Tablet is used to treat the symptoms of dementia in people with mild and moderately severe Alzheimer's disease. Alzheimer’s disease is a brain condition that slowly damages memory, thinking, learning, and organizing skills. It is the most common cause of dementia, mainly affecting older adults. As the disease progresses, it leads to significant cognitive decline and changes in behaviour and personality.

Nepzil 10mg Tablet contains Donepezil, which works by increasing the levels of a substance (acetylcholine) in the brain involved in memory function by slowing down the breakdown of acetylcholine. Thereby, it helps treat symptoms of dementia in patients with Alzheimer's disease.

The dose and duration of treatment with Nepzil 10mg Tablet can be determined by the doctor based on your medical condition. In some cases, Nepzil 10mg Tablet may cause side effects such as diarrhoea, nausea, headache, muscle cramps and tiredness. Most of these side effects do not require medical attention and resolve gradually over time. However, if the side effects persist or worsen, consult the doctor.

Do not take Nepzil 10mg Tablet if you are allergic to Nepzil 10mg Tablet or any of its components. Inform the doctor if you have a heart rhythm disorder, a stomach ulcer, urination problems, asthma or other breathing disorders, seizures or liver disease before taking Nepzil 10mg Tablet. Consult the doctor if you are pregnant or breastfeeding before taking Nepzil 10mg Tablet. Also, keep the doctor informed about your health condition and any medications you are taking to rule out any potential side effects or interactions. Nepzil 10mg Tablet should be used for children only if prescribed by the doctor.

Uses of Nepzil 10mg Tablet

Nepzil 10mg Tablet is used to manage cognitive symptoms associated with neurodegenerative disorders. The detailed uses of Nepzil 10mg Tablet are as follows:<br/> • Treatment of dementia symptoms in alzheimer's disease: Nepzil 10mg Tablet is prescribed to improve memory, awareness, and the ability to perform daily functions in individuals with mild to moderate Alzheimer's disease. It works by enhancing communication between nerve cells in the brain.<br/>

Directions for Use

  • Nepzil 10mg Tablet can be taken with or without food, as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Nepzil 10mg Tablet as a whole with a glass of water.
  • Do not crush, chew or break it.

Medicinal Benefits

Nepzil 10mg Tablet belongs to the group of medicines called acetylcholinesterase inhibitors used to treat the symptoms of dementia in people with mild and moderately severe Alzheimer's disease. Nepzil 10mg Tablet contains Donepezil, which works by increasing the levels of a substance (acetylcholine) in the brain involved in memory function by slowing down the breakdown of acetylcholine. Thereby, it helps treat symptoms of dementia in patients with Alzheimer's disease.

How Nepzil 10mg Tablet Works

Nepzil 10mg Tablet contains Donepezil, which works by increasing the levels of a substance (acetylcholine) in the brain involved in memory function by slowing down the breakdown of acetylcholine. Thereby, it helps treat symptoms of dementia in patients with Alzheimer's disease.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Nepzil 10mg Tablet
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
  • Avoid massaging the bruise, as this might worsen the damage to the injured tissue.
  • Resting the affected area helps prevent more injury and aids healing.
  • Place a cloth-wrapped ice pack or cold compress on the affected area for 10 to 15 minutes.
  • If the bruise is extensive, severe, or accompanied by other symptoms like warmth, redness, or swelling, get medical help.
  • Please inform your doctor about joint swelling, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Maintain a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet.
  • Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Whenever there is swelling, apply heat or cold packs to the affected joint that can help reduce pain and inflammation.
  • Track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
  • Take rest and refrain from doing physical activity for a while, and restart after a few days.
  • Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
  • Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.
  • Dehydration would need immediate medical attention if its severe where medical help can save you from crisis.
  • In case the level of dehydration is from mild to moderate, drink plenty of water for an immediate relief.
  • Seek a place where the surrounding temperature is less and try to stay away from heat and humidity.
  • Lie down by keeping a cool and wet towel on your forehead to prevent high temperature in your body to avoid dehydration.
  • Talk to your medical practitioner and use oral rehydrating salts to replace the lost salts from your body.

What if I have taken an overdose of Nepzil 10mg Tablet

Do not take more than the prescribed dose of Nepzil 10mg Tablet, as it may cause an overdose. The symptoms of overdose include vomiting, severe nausea, blurred vision, sweating, drooling, feeling lightheaded, seizures (fits), shallow breathing, slow heartbeat, fainting or muscle weakness. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Nepzil 10mg Tablet if you are allergic to Nepzil 10mg Tablet or any of its components. Inform the doctor if you have liver or kidney disease, stomach or duodenal ulcer, seizure or convulsions, heart problems, low levels of potassium or magnesium, lung disease, or extrapyramidal symptoms. Consult the doctor if you are pregnant or breastfeeding. Keep the doctor informed about your health condition and medications to rule out any side effects/interactions.

Drug-Drug Interactions

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DonepezilBupropion
Severe
DonepezilIohexol
Severe

Drug-Drug Interactions

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DonepezilBupropion
Severe
How does the drug interact with Nepzil 10mg Tablet:
Taking bupropion with Nepzil 10mg Tablet may increase the levels of Nepzil 10mg Tablet and the risk of developing seizures.

How to manage the interaction:
Co-administration of bupropion along with Nepzil 10mg Tablet can lead to an interaction, but it can be taken when recommended by a doctor. However, if you experience sudden dizziness, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
DonepezilIohexol
Severe
How does the drug interact with Nepzil 10mg Tablet:
Coadministration of Iohexol and Nepzil 10mg Tablet can increase the risk of developing seizures. The risk increases in patients with a history of seizure or head injury.

How to manage the interaction:
Although taking Nepzil 10mg Tablet and Iohexol together can cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without first talking to your doctor.
DonepezilTramadol
Severe
How does the drug interact with Nepzil 10mg Tablet:
Coadministration of Nepzil 10mg Tablet with tramadol can increase the risk of developing seizures. The risk increases in patients with a history of seizure or head injury.

How to manage the interaction:
Taking Nepzil 10mg Tablet with tramadol together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms such as confusion, increased heart rate, blurred vision, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DonepezilIomeprol
Severe
How does the drug interact with Nepzil 10mg Tablet:
Co-administration of Iomeprol and Nepzil 10mg Tablet can increase the risk of developing seizures. The risk increases in patients with a history of seizure or head injury.

How to manage the interaction:
Co-administration of Nepzil 10mg Tablet with Iomeprol can possibly result in an interaction, but it can be taken if your doctor has advised it. Contact your doctor if you experience any symptoms like shortness of breath, irregular heart rhythms, or problems with movement and memory. Do not discontinue any medications without first consulting your doctor.
DonepezilCyclopentolate
Severe
How does the drug interact with Nepzil 10mg Tablet:
Coadministration of Cyclopentolate with Nepzil 10mg Tablet can reduce the levels and effects of Cyclopentolate.

How to manage the interaction:
There may be a possibility of interaction between Cyclopentolate and Nepzil 10mg Tablet, but it can be taken when prescribed by a doctor. However, if you experience any symptoms like sudden dizziness, shortness of breath, or rapid heartbeat consult your doctor immediately. Do not stop using any medications without talking to your doctor.
DonepezilIopamidol
Severe
How does the drug interact with Nepzil 10mg Tablet:
The combined use of iopamidol and Nepzil 10mg Tablet can increase the risk of developing seizures. The risk increases in patients with a history of seizures or head injury.

How to manage the interaction:
Taking Nepzil 10mg Tablet with Iopamidol together can possibly result in an interaction, but it can be taken if your doctor has advised it. Contact your doctor if you experience any symptoms like shortness of breath, irregular heart rhythms, or problems with movement and memory. Do not stop using any medications without a doctor's advice.
DonepezilMetrizamide
Severe
How does the drug interact with Nepzil 10mg Tablet:
The combined use of metrizamide and Nepzil 10mg Tablet can increase the risk of developing seizures. If you have a history of seizures or a head injury, contact your doctor immediately.

How to manage the interaction:
Although there is a possible interaction between Nepzil 10mg Tablet and Metrizamide, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A person dealing with Alzheimer's disease needs to take proper nutrition to make their body strong and healthy. For a patient dealing with dementia, poor nutrition can affect behavioral symptoms and may cause weight loss.
  • Consume more whole grains, low-fat dairy products, vegetables, fruits, and lean protein foods, and cut down high saturated fat, refined sugars, and cholesterol from your diet.
  • Patients dealing with dementia should do meditation activities that help calm down their minds and make medicine work more efficiently.
  • Engage in physical exercises like walking, stretching or yoga to enhance mood.
  • Interacting regularly with friends or family can improve mood and mental function.
  • Engage in reading books, puzzles, learning new skills or memory games to stay mentally active.

Habit Forming

No

Therapeutic Class

ANTI- ALZHEIMER'S AGENTS

Nepzil 10mg Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

It is advised to avoid alcohol consumption while taking Nepzil 10mg Tablet, as alcohol can worsen dementia symptoms and reduce the effectiveness of the medication.

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Pregnancy

Caution

Please consult the doctor if you are pregnant before taking Nepzil 10mg Tablet. The doctor may prescribe this medication only if the benefits outweigh the risks.

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Breast Feeding

Caution

It is unknown whether Nepzil 10mg Tablet passes into breast milk. Therefore, please consult the doctor if you are breastfeeding before taking Nepzil 10mg Tablet.

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Driving

Caution

Nepzil 10mg Tablet may cause dizziness. Therefore, avoid driving or operate heavy machinery until you are fully alert.

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Liver

Caution

If you have any concerns regarding the use of Nepzil 10mg Tablet in patients with liver problems, please consult a doctor.

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Kidney

Caution

If you have any concerns about using Nepzil 10mg Tablet in patients with kidney problems, please consult a doctor.

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Children

Caution

Nepzil 10mg Tablet should be used for children only if prescribed by the doctor. Please consult the doctor before using Nepzil 10mg Tablet to your child.

Have a query?

FAQs

Nepzil 10mg Tablet belongs to the group of medicines called acetylcholinesterase inhibitors. It is used to treat the symptoms of dementia in people with mild and moderately severe Alzheimer's disease.

Nepzil 10mg Tablet belongs to the group of medicines called acetylcholinesterase inhibitors. It works by increasing the levels of a substance (acetylcholine) in the brain involved in memory function by slowing down the breakdown of acetylcholine.

Do not stop taking Nepzil 10mg Tablet unless told to do so by your doctor. If you stop taking Nepzil 10mg Tablet, the benefits of your treatment will gradually fade away.

Nepzil 10mg Tablet may cause side effects such as nausea, vomiting, diarrhoea, loss of appetite, muscle cramps, weakness and unusual tiredness. If these side effects persist or worsen, please consult your doctor.

Nepzil 10mg Tablet results in bone weakness and can increase the risk of fractures in elderly patients if taken in high doses for an extended period of time.

Nepzil 10mg Tablet may cause diarrhoea as a common side effect but sometimes can be serious. Nepzil 10mg Tablet reduces the levels of gastric acid and can increase the bacterial count in the gut and can lead to infections. Thus, if you have persistent diarrhoea, consult your doctor immediately.

The long term use of the Nepzil 10mg Tablet results in liver function disturbances, changes in electrolyte (magnesium, calcium and sodium) levels and B12 deficiency. Therefore, if you experience symptoms such as loss of appetite, yellow skin and eyes, nausea, dizziness, itching, fits, headache, tiredness, irritability, or pale skin, consult your doctor immediately. As you have been prescribed Nepzil 10mg Tablet for a long duration, your doctor may recommend regular follow-ups and blood tests.

Yes, you can Nepzil 10mg Tablet on an empty stomach or with food or as advised by your doctor. But take it at the same time every day for best results.

Country of origin

India
Other Info - NE54357

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 22, 2025 | 8:52 AM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/020690s035,021720s008,022568s005lbl.pdf
  2. https://www.medicines.org.uk/emc/files/pil.4428.pdf
  3. https://www.drugs.com/mtm/donepezil.html
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