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compositionComposition:ACECLOFENAC-200MG+PREGABALIN-75MG
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Prescription Medicine
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Nervitop AP 200/75 Tablet is used to treat neuropathic pain. It contains Pregabalin and Aceclofenac which work modulating nerve cell activity and inhibiting chemical messengers that cause pain. In some cases, this medicine may cause side effects such as nausea, vomiting, stomach pain, diarrhoea, loss of appetite, heartburn, dry mouth, dizziness, and sleepiness. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

ACECLOFENAC-200MG+PREGABALIN-75MG

Manufacturer/Marketer :

Zerico Lifesience Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Nervitop AP 200/75 Tablet

Nervitop AP 200/75 Tablet is a medication used to manage moderate-to-severe pain involving both nerve damage and tissue inflammation. It is commonly prescribed to treat conditions where muscle stiffness, swelling, and burning or shooting nerve pain occur together. By addressing both nerve sensitivity and joint or muscle swelling, this medication helps restore physical comfort.

For the best results, it is important to take Nervitop AP 200/75 Tablet consistently at the same times each day as directed by your healthcare provider. This tablet is generally taken with food to protect your stomach lining from potential irritation. Along with taking your medication, incorporating light physical therapy and gentle stretching, and maintaining a balanced diet can help support your overall recovery.

While taking Nervitop AP 200/75 Tablet , some people may experience common, mild side effects such as drowsiness, dizziness, or an upset stomach. These side effects often subside as your body adjusts to the medication. However, you must consult your doctor immediately if you experience serious symptoms, such as severe stomach pain, swelling of the face or limbs, or dark, tarry stools.

This medication can interact with other substances, including sleeping pills, muscle relaxants, and certain pain relievers, which can increase the risk of extreme drowsiness. Avoid drinking alcohol while taking Nervitop AP 200/75 Tablet , as it can worsen dizziness and increase the risk of stomach bleeding. Specific patient groups, such as pregnant women, breastfeeding mothers, and elderly individuals, must consult their doctor before starting this treatment.

Uses of Nervitop AP 200/75 Tablet

Your doctor may prescribe this medicine to treat several conditions, including:

  • Neuropathic Pain with Inflammation: Nervitop AP 200/75 Tablet helps calm damaged, hyperactive nerve fibres while simultaneously lowering tissue inflammation and swelling.
  • Sciatica: It relieves sharp, radiating nerve pain that travels down the leg and reduces inflammation around the spinal nerve roots.
  • Chronic Back Pain: It addresses both mechanical joint inflammation and nerve compression, helping to reduce persistent backaches. 

Key Benefits

Here are the key benefits for effective pain relief:

  • Relieves Nerve Pain: Nervitop AP 200/75 Tablet offers comprehensive relief by targeting pain from two different angles. Instead of just masking symptoms, it calms overactive pain signals in the nervous system while lowering the chemical signals that cause painful swelling in muscles and joints.
  • Improves Mobility: This dual action helps improve your daily physical functioning. By reducing stiffness and sharp nerve pain, Nervitop AP 200/75 Tablet allows you to move more freely, perform daily chores, and participate in physical rehabilitation with less discomfort.
  • Supports Better Sleep: Additionally, easing persistent nighttime nerve pain and muscle aches helps improve sleep quality, which is crucial for your body's natural healing process and overall well-being. 

Directions for Use

  • Nervitop AP 200/75 Tablet can be taken with or without food, but taking it with food can help minimize stomach discomfort.
  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Swallow Nervitop AP 200/75 Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Nervitop AP 200/75 Tablet Works

The first active ingredient is aceclofenac, which belongs to a class of medications called non-steroidal anti-inflammatory drugs NSAIDs, a group of medicines that reduce pain and swelling. Its mechanism of action works by inhibiting COX enzymes, reducing prostaglandin synthesis, which in turn reduces pain and inflammation. The second active ingredient is pregabalin, which belongs to a class of medicines called anticonvulsants/gabapentinoid(alpha-2-delta calcium channel ligand). It works by attaching to calcium channels in nerve cells, blocking the pain messages to the brain. This helps relieve nerve pain Together, these two ingredients provide comprehensive relief by cooling down both localised tissue swelling and nerves becoming too sensitive throughout the body.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Nervitop AP 200/75 Tablet as it may increase drowsiness and sleepiness.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Nervitop AP 200/75 Tablet ; your doctor will decide whether Nervitop AP 200/75 Tablet can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Nervitop AP 200/75 Tablet causes drowsiness, sleepiness, and blurred vision. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Nervitop AP 200/75 Tablet should not be given to children as the safety and efficacy have not been established.

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Heart

Caution

Nervitop AP 200/75 Tablet should be taken with caution in patients with heart disease. Please consult your physician.

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Geriatrics

Caution

Nervitop AP 200/75 Tablet can be given in elderly patients with extreme caution, due to the cause of adverse effects.

What if I have taken an overdose of Nervitop AP 200/75 Tablet

If you accidentally take more than your prescribed dose, seek immediate medical attention. Symptoms of an overdose may include severe drowsiness, confusion, shallow breathing, or severe stomach pain, respiratory depression, and coma.

Diet & Lifestyle Advise

  • Avoid Alcohol: Avoid drinking alcohol, as it can significantly increase the drowsiness caused by pregabalin and increase your risk of stomach bleeding from aceclofenac.
  • Stay Active: Incorporate low-impact activities, such as swimming or walking, to keep your joints flexible and strengthen muscles without putting excess strain on your nerves.
  • Stay Hydrated: Stay well-hydrated throughout the day to support your kidney function, which is essential when taking pain-relieving medications.
  • Eat a Healthy Diet: Focus on a nutrient-rich, anti-inflammatory diet containing leafy green vegetables, berries, and healthy fats to help naturally support your recovery.
  • Do Not Share Your Medicine: Patients should never share prescription medication with others. 
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How Soon It Starts Working

The time required for Nervitop AP 200/75 Tablet to start to work: Nervitop AP 200/75 Tablet ideally shows its action within 30 to 60 minutes of administration. The time for which the effects of Nervitop AP 200/75 Tablet last: Nervitop AP 200/75 Tablet effect lasts for 8 to 12 hours.

What if you forget to take Nervitop AP 200/75 Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store Nervitop AP 200/75 Tablet at room temperature, ideally between 15°C and 30°C (59°F to 86°F), in a dry place.

Drug Warnings

  • Avoid Driving or Operating Machinery: Do not drive, operate heavy machinery, or perform hazardous tasks until you are sure how Nervitop AP 200/75 Tablet affects your alertness and physical coordination.
  • Do not stop taking this medication suddenly: As abruptly stopping pregabalin can lead to withdrawal symptoms such as anxiety, sweating, headaches, and trouble sleeping. Your doctor will guide you on gradually decreasing the dose or tapering off safely.
  • Inform your doctor: Inform the Surgeon, anesthesiologist, or dentist that you are taking Nervitop AP 200/75 Tablet before undergoing any scheduled medical or dental procedures.
  • Watch for Stomach Bleeding: Monitor your stool and digestive health regularly; seek immediate medical care if you notice dark, tarry stools or vomit that looks like coffee grounds. 

verifiedApollotooltip

Some medicines can affect how Nervitop AP 200/75 Tablet works or increase the risk of side effects. Tell your doctor about all the medicines and supplements you are taking.

  • Central Nervous System Depressants: Taking this medicine with sleeping pills, anxiety medications, or muscle relaxants can cause extreme drowsiness and slow breathing.
  • Other Pain Relievers: Combining this medication with other NSAIDs (like ibuprofen) or aspirin increases the risk of stomach irritation, ulcers, and internal bleeding.

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verifiedApollotooltip

No clinically significant food interactions are known with Nervitop AP 200/75 Tablet when used as directed.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTICONVULSANT]

FAQs

Nervitop AP 200/75 Tablet is used to treat neuropathic pain, a nerve disease that causes nerve pain due to nerve damage.
Nervitop AP 200/75 Tablet is a combination of two drugs: Pregabalin (anti-convulsant), and Aceclofenac (NSAID). Pregabalin works by changing how nerves send messages to your brain. Aceclofenac work by blocking the effect of a natural chemical messenger called cyclo-oxygenase (COX) enzymes that make another chemical (prostaglandins). These prostaglandins are produced at sites of damage or injury and cause inflammation and pain. Together, Nervitop AP 200/75 Tablet helps to treat neuropathic pain (pain due to nerve damage).
Some people may experience weight gain while taking Nervitop AP 200/75 Tablet . This may occur due to an increased appetite or mild fluid retention caused by pregabalin. Maintain a healthy weight through regular exercise and a balanced diet. If you notice rapid or unusual weight gain or swelling of your hands or feet, talk to your doctor.
Nervitop AP 200/75 Tablet is used to treat neuropathic pain due to diabetic neuropathy. Diabetic neuropathy is a condition in which nerve damage occurs due to high blood glucose levels. It mostly damages the nerves in legs and feet.
No, you should avoid alcohol while taking this medicine. Alcohol can worsen side effects like dizziness and sleepiness, and it significantly increases the risk of stomach irritation and bleeding. Talk to your doctor if you have questions.
Yes, drowsiness and sleepiness are common side effects of this medication, especially during the first few days of treatment. Avoid driving or operating machinery if you feel drowsy. Talk to your doctor if this sleepiness interferes with your daily activities.
You should use this medication with caution if you have high blood pressure, as the aceclofenac component can cause fluid retention, which may raise blood pressure levels. Your doctor will monitor your cardiovascular health during treatment. Talk to your doctor.
Do not take this medication if you are pregnant or planning to become pregnant unless your doctor explicitly advises it. Aceclofenac should not be used during the third trimester of pregnancy. Pregabalin should only be used in pregnancy if the benefit outweighs the risk.
No. Do not stop taking Nervitop AP 200/75 Tablet suddenly, even if your pain improves or you feel well. Abrupt discontinuation may cause withdrawal symptoms such as anxiety, insomnia, sweating, and a rapid heart rate. Continue taking it for as long as prescribed, and if treatment needs to be stopped, your doctor will gradually reduce the dose.
Dry mouth is a common side effect of pregabalin. To help relieve it, sip water frequently, chew sugar-free gum, or suck on sugar-free hard candies. Avoid smoking, excessive caffeine, and alcohol-containing mouthwashes, as they may worsen dry mouth. Talk to your doctor or pharmacist if it persists or becomes bothersome.
Do not take this if you have a history of active stomach ulcers, severe heart failure, severe liver damage, or advanced kidney disease. Before starting this medication, talk to your doctor if you have a history of asthma, high blood pressure, fluid retention, or seizures, as these conditions require close monitoring during treatment.

Disclaimer

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Reference

  1. Electronic Medicines Compendium (EMC). Pil.7448 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. Electronic Medicines Compendium (EMC). Pil.4240 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  3. National Health Service (NHS). Pregabalin - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  4. Pregabalin Pregabalin. 2009. [Accessed on 22 Apr. 2019]Check here
  5. Pregablin Pregablin. 2004. [Accessed on 22 Apr. 2019]Check here
  6. Laboratories BTT. Aceclofenac 100 mg Film-coated Tablets Aceclofenac. Electronic Medicines Compendium. [Revised in January 2016]. [Accessed on 14th January 2023].Check here
  7. MSN Laboratories Europe Limited. Pregabalin. Electronic Medicines Compendium. [Revised in March 2022]. [Accessed on 14th January 2023].Check here

Country of origin

India

Manufacturer/Marketer address

Zerico Lifesciences Pvt Ltd, 8,Solitaire Ii,Poonam Garden, Mira Road East,Mumbai. , Maharastra., Pin 401107.
Other Info - NER0591

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