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  3. Nevir-ER Tablet 30's

Nevir-ER Tablet 30's, Pack of 1 TABLET
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Composition :

NEVIRAPINE-400MG

Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Nevir-ER Tablet

Nevir-ER Tablet is an antiretroviral medicine used in the treatment of HIV. Human Immunodeficiency Virus (HIV) is a retroviral infection that attacks and damages the cells of the immune system. This weakens the ability to fight against infections and diseases. If this condition is left untreated, it can lead to Acquired Immuno Deficiency Syndrome (AIDS). Nevir-ER Tablet is combined with other antiretroviral medicines to treat HIV infection.

Nevir-ER Tablet contains Neviparine, which belongs to the class of non-nucleoside reverse transcriptase inhibitor (NNRTI). It works by inhibiting the HIV reverse transcriptase enzymes that are necessary for the virus's DNA reproduction. This causes inhibition of DNA replication and thereby prevents further spread of infection.

Nevir-ER Tablet may cause side effects such as nausea, headache, abdominal pain, loss of appetite, vomiting, fatigue, diarrhoea, myalgia (muscle pain), skin rash and other allergic reactions. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. Nevir-ER Tablet should be taken as advised by your doctor. Your doctor will decide the dose of the medicine based on your health condition. Do not take more than the recommended dose.

Nevir-ER Tablet should be avoided if you are allergic to it. This medicine is contraindicated in patients with moderate to severe hepatic impairment or used as an occupational or non-occupational post-exposure prophylaxis. Nevir-ER Tablet is known you cause fatal or non-fatal hepatotoxicity and skin disorders. Hence, careful monitoring should be done during the first 18 weeks of the treatment initiation. Before taking this medicine, inform your doctor if you have liver/kidney disease, hypersensitivity reactions, Stevens-Johnson syndrome, toxic epidermal necrolysis, cirrhosis, or hepatic fibrosis. If you are pregnant and breastfeeding, let your doctor know before taking Nevir-ER Tablet . Nevir-ER Tablet should be used in children only if recommended by the doctor. 

Uses of Nevir-ER Tablet

Nevir-ER Tablet is used in the treatment of Human Immunodeficiency Virus (HIV) Infection. The detailed uses of Nevir-ER Tablet are as follows:<br/>• Treatment of HIV-1 infection: Nevir-ER Tablet used in the treatment of HIV-1 infection.<br/>• Improve immune function: Nevir-ER Tablet helps reduce viral load and increase CD4 cell counts, improving immune function and slowing disease progression.<br/>

Directions for Use

• Nevir-ER Tablet can be taken with or without food because food does not impact its effectiveness.• It is usually taken once or twice a day; however, follow your doctor's advice regarding the dosage and duration.• Swallow the medicine as a whole with a glass of water.• Do not break, chew or crush Nevir-ER Tablet .

Medicinal Benefits

Nevir-ER Tablet contains Neviparine, which belongs to the class of non-nucleoside reverse transcriptase inhibitor (NNRTI). It works by inhibiting the HIV reverse transcriptase enzymes that are necessary for the virus's DNA reproduction. This causes inhibition of DNA replication and thereby prevents further spread of infection. Nevir-ER Tablet is used in combination with other antiretroviral medicines to help reduce the symptoms, control the infection, and prevent opportunistic infections effectively. It also helps in improving the quality of life of a patient with HIV. 

How Nevir-ER Tablet Works

Nevir-ER Tablet contains Neviparine, which belongs to the class of non-nucleoside reverse transcriptase inhibitor (NNRTI). It works by inhibiting the HIV reverse transcriptase enzymes that are necessary for the virus's DNA reproduction. This causes inhibition of DNA replication and thereby prevents further spread of infection.

Storage

Store in a cool and dry place away from sunlight
Side effects of Nevir-ER Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
  • Avoid contact with people who are sick.
  • Wash your hands regularly with soap and water.
  • Avoid unpasteurized dairy products.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
  • Maintain good oral hygiene.
  • Rinsing with salt water may also help relieve mouth ulcers.
  • Avoid foods that cause inflammation like spicy, salty or sugary foods.
  • Eat soft foods like yoghurt, apple sauce, and mashed potatoes.
  • Drink enough fluids.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

What if I have taken an overdose of Nevir-ER Tablet

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Nevir-ER Tablet may include dizziness, difficulty falling asleep or staying asleep, excessive tiredness, fever, headache, nausea, painful red bumps on the skin, rash, swelling of the hands, feet, ankles, or lower legs, and vomiting. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Nevir-ER Tablet should be avoided if you are allergic to it. This medicine is contraindicated in patients with moderate to severe hepatic impairment or used as an occupational or non-occupational post-exposure prophylaxis. This medicine should only be prescribed in patients with CD4+ greater than 250 cells/mm3 (females) and 400 cells/mm3 (males). Inform your doctor about your medical history and the medicines you take to prevent possible interactions. Nevir-ER Tablet is known you cause fatal or non-fatal hepatotoxicity and skin disorders. Hence, careful monitoring should be done during the first 18 weeks of the treatment initiation. If the patient develops any signs or symptoms of hepatitis, increased transaminase, rash, or hypersensitivity reactions, Nevir-ER Tablet should be discontinued immediately. This medicine may cause dizziness; hence, avoid driving or operating machines while taking Nevir-ER Tablet . Before taking this medicine, inform your doctor if you have liver/kidney diseases, hypersensitivity reactions, Stevens-Johnson syndrome, toxic epidermal necrolysis, cirrhosis, or hepatic fibrosis. If pregnant and breastfeeding, inform your doctor before taking Nevir-ER Tablet . Nevir-ER Tablet should be used in children only if recommended by the doctor. If prescribed, the child should be carefully monitored for any changes. Nevir-ER Tablet treats the infection but does not cure or prevent it.

Drug-Drug Interactions

verifiedApollotooltip
NevirapineAtazanavir
Critical
NevirapineRanolazine
Critical

Drug-Drug Interactions

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NevirapineAtazanavir
Critical
How does the drug interact with Nevir-ER Tablet:
When Atazanavir is taken with Nevir-ER Tablet, it can reduce the levels and side effects of atazanavir & increase the blood levels and effects of Nevir-ER Tablet.

How to manage the interaction:
Taking Nevir-ER Tablet with Atazanavir is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience a rash on any parts of your body, loss of appetite, nausea, vomiting, jaundice (yellowing of the skin and/or eyes), dark-coloured urine, pale-coloured stools, or pain or ache in the right abdominal area below your ribs, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NevirapineRanolazine
Critical
How does the drug interact with Nevir-ER Tablet:
Co-administration of Nevir-ER Tablet with Ranolazine may significantly reduce the blood levels of Ranolazine. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Nevir-ER Tablet with Ranolazine is generally avoided as it can lead to an interaction, they can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
NevirapineLomitapide
Severe
How does the drug interact with Nevir-ER Tablet:
Coadministration of Nevir-ER Tablet and Lomitapide may increase the risk or severity of liver problems.

How to manage the interaction:
Although taking Nevir-ER Tablet and Lomitapide together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes call a doctor right away. Do not discontinue any medications without consulting a doctor.
NevirapineDaclatasvir
Severe
How does the drug interact with Nevir-ER Tablet:
Using Nevir-ER Tablet together with daclatasvir may decrease the blood levels of daclatasvir.

How to manage the interaction:
Taking Daclatasvir with Nevir-ER Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without a doctor's advice.
NevirapineVoclosporin
Severe
How does the drug interact with Nevir-ER Tablet:
Coadministration of Nevir-ER Tablet with Voclosporin may lower voclosporin blood levels, which might lessen how well it works to treat your disease.

How to manage the interaction:
Co-administration of Nevir-ER Tablet with Voclosporin can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to a doctor.
NevirapineOlaparib
Severe
How does the drug interact with Nevir-ER Tablet:
When Olaparib is taken with Nevir-ER Tablet may reduce the blood levels of Olaparib. This can lead to low treatment outcomes.

How to manage the interaction:
There may be a possibility of interaction between Nevir-ER Tablet and Olaparib, but it can be taken if prescribed by a doctor. Do not discontinue any medications without first consulting a doctor.
NevirapineLeflunomide
Severe
How does the drug interact with Nevir-ER Tablet:
Coadministration of Nevir-ER Tablet and leflunomide can increase the risk of liver problems.

How to manage the interaction:
Although there is an interaction between leflunomide and Nevir-ER Tablet, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NevirapineMipomersen
Severe
How does the drug interact with Nevir-ER Tablet:
Coadministration of Nevir-ER Tablet and Mipomersen can increase the risk and severity of liver problems.

How to manage the interaction:
Although taking Nevir-ER Tablet and Mipomersen together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you have any symptoms like fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark urine, or bleeding make sure to contact your doctor immediately. Do not stop using any medications without a doctor's advice.
NevirapineTeriflunomide
Severe
How does the drug interact with Nevir-ER Tablet:
Coadministration of Nevir-ER Tablet and Teriflunomide can increase the risk and severity of liver problems.

How to manage the interaction:
Although taking Nevir-ER Tablet and Teriflunomide together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms - fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-coloured urine, or bleeding make sure to contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NevirapineRifampicin
Severe
How does the drug interact with Nevir-ER Tablet:
Taking Nevir-ER Tablet with rifampicin can decrease the blood levels of Nevir-ER Tablet, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Nevir-ER Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food such as vegetables and fruit as it helps to boost your immune system. Try to take lean protein and whole grains.
  • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.
  • Eat bland and low-fat foods, and avoid spicy or oily foods if you experience nausea or vomiting.
  • Get tested for other sexually transmitted infections, such as gonorrhoea or syphilis.
  • Try to reduce emotional and physical stress by spending time with your family or doing whatever makes you happy.
  • Drink more fluids and avoid alcoholic beverages to prevent dehydration.  
  • Never share personal items with body fluids or blood on them, such as razor blades or toothbrushes.
  • Avoid sharing used needles, other injection or drug equipment.

Habit Forming

No

Therapeutic Class

ANTIRETROVIRAL AGENTS
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Alcohol

Unsafe

Avoid alcohol consumption while on treatment with Nevir-ER Tablet . Alcohol intake might increase the risk of stomach or intestine bleeding.

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Pregnancy

Consult your doctor

If you are pregnant or suspect you may be pregnant, inform your doctor before taking Nevir-ER Tablet . Your doctor will prescribe a suitable dose of this medicine to prevent maternal-fetal HIV transmission.

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Breast Feeding

Unsafe

Nevir-ER Tablet is excreted in milk. If you have HIV or are taking Nevir-ER Tablet , you should not breastfeed your baby.

bannner image

Driving

Unsafe

Avoid driving vehicles after taking Nevir-ER Tablet as it may cause fatigue.

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Liver

Caution

Nevir-ER Tablet can result in serious, sometimes fatal, liver damage. Inform your doctor if you have or have had a liver illness, particularly hepatitis B or C. Your doctor will most likely advise you not to take Nevir-ER Tablet .

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Kidney

Caution

Before using Nevir-ER Tablet , inform your doctor if you have or have ever had kidney disease, particularly if you are on dialysis treatment.

bannner image

Children

Consult your doctor

Please consult your doctor. Your doctor will decide the dose of this medicine based on the age and condition of your child.

Have a query?

FAQs

Nevir-ER Tablet is used to treat HIV infection.

Nevir-ER Tablet contains Neviparine, which works by inhibiting the HIV reverse transcriptase enzymes that are necessary for the virus&amp;#039;s DNA reproduction. This causes inhibition of viral replication and thereby prevents further spread of infection.

No, completing the entire treatment course prescribed by the doctor is always recommended. Sudden discontinuation of the medicine can lead to serious side effects. Your doctor will decide whether to stop the medication or not.

Nevir-ER Tablet does not cure HIV infection. However, it helps to control the disease and prevent opportunistic infections. Nevir-ER Tablet is used in combination with other anti-retroviral medicines.

Nevir-ER Tablet is an antiretroviral medicine. It contains Neviparine, which belongs to the class of non-nucleoside reverse transcriptase inhibitors (NNRTI) used to treat HIV infection.

Yes, Nevir-ER Tablet is safe if taken in the dose and duration prescribed by the doctor.

Nevir-ER Tablet can be taken with or without food. Swallow it as a whole with a glass of water. Do not chew, crush, or break the medicine.

Yes, Nevir-ER Tablet is an effective antiretroviral medicine used in the treatment of Human Immunodeficiency Virus (HIV) infection.

If you miss a dose of Nevir-ER Tablet , take it as soon as you remember. However, if it is almost time for the scheduled dose, skip the missed dose and take the next dose at the scheduled time.

Nevir-ER Tablet may cause side effects such as nausea, headache, abdominal pain, loss of appetite, vomiting, fatigue, diarrhoea, myalgia (muscle pain), skin rash and other allergic reactions. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

A €“ 504, Shapath-4, B/S Hotel Crowne Plaza, Opp. Karnavati Club, S. G. Highway ,Ahmedabad 380 051 Gujarat
Other Info - NEV0080

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:20 PM IST

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Reference

  1. https://www.ncbi.nlm.nih.gov/books/NBK554477/#:~:text=Nevirapine%20is%20a%20drug%20used,antiretroviral%20therapy%20(ART)%20medications.
  2. https://go.drugbank.com/drugs/DB00238
  3. https://medlineplus.gov/druginfo/meds/a600035.html
  4. https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/020636s039_020933s030lbl.pdf

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