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compositionComposition:BEMPEDOIC ACID-180MG
prescription
Prescription Medicine
info
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Nexred 180Mg Tab is used to lower the high cholesterol together with lifestyle changes (diet, weight loss, exercise). It contains Bempedoic acid, which works by blocking an enzyme (ATP citrate lyase) needed for the production of cholesterol. This helps block the production of cholesterol in the liver and increases the removal of LDL cholesterol. Thereby, it helps decrease bad cholesterol in the body.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

BEMPEDOIC ACID-180MG

Manufacturer/Marketer :

Dr Reddy's Laboratories Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Nexred 180Mg Tab

Nexred 180Mg Tab is used together with lifestyle changes and certain cholesterol-lowering medicines to decrease bad cholesterol in patients with heart disease or familial heterozygous hypercholesterolemia (an inherited condition in which cholesterol cannot be removed from the body normally).

Nexred 180Mg Tab contains Bempedoic acid, which works by blocking an enzyme (ATP citrate lyase) needed for the production of cholesterol. This helps block the production of cholesterol in the liver and increases the removal of LDL cholesterol. Thereby, it helps decrease bad cholesterol in the body.

In some cases, Nexred 180Mg Tab may cause side effects such as anaemia, gout, and pain in the shoulders, arms or legs. Most of these side effects may not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.

Do not take Nexred 180Mg Tab if you are pregnant or breastfeeding. Nexred 180Mg Tab is not recommended for children below 18 years, as the safety and effectiveness have not been established. Inform the doctor regarding your health condition and medicines you are taking to rule out any possible side effects/interactions.

Uses of Nexred 180Mg Tab

Nexred 180Mg Tab is used in the treatment of high cholesterol. The detailed uses of Nexred 180Mg Tab are as follows:

  • Lowering LDL cholesterol: Nexred 180Mg Tab is prescribed to reduce low-density lipoprotein cholesterol (LDL-C), commonly known as bad cholesterol. It works by inhibiting the enzyme ATP citrate lyase, which plays a key role in cholesterol production in the liver.
  • Treatment of primary hyperlipidemia: Nexred 180Mg Tab is used in adults with primary hyperlipidemia, including heterozygous familial hypercholesterolemia, a genetic condition that causes very high cholesterol levels.
  • Cardiovascular risk reduction: In patients with established heart disease or those at high risk, Nexred 180Mg Tab may be used alongside statins or as an alternative when statins are not tolerated, to help reduce the risk of heart attack, stroke, or coronary procedures.

Key Benefits

  • Nexred 180Mg Tab belongs to a group of medicines called adenosine triphosphate-citrate lyase (ACL) inhibitors used in addition to the cholesterol-lowering diet in adult patients with primary hypercholesterolaemia (high cholesterol) or mixed dyslipidaemia (imbalance of lipids).
  • Nexred 180Mg Tab contains bempedoic acid, which works by blocking an enzyme (ATP citrate lyase) needed for the production of cholesterol.
  • This helps block the production of cholesterol in the liver and increases the removal of LDL cholesterol.
  • It helps decrease bad cholesterol in the body.
Side effects of Nexred 180 mg Tablet
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Increased creatinine levels must be corrected immediately with the help of a doctor.
  • Reduce strenuous activities that can lead to muscle breakdown and production of creatinine.
  • Sleep for 7-8 hours per night to assist your body in repairing and rebuilding tissue.
  • Manage your blood pressure by implementing changes in lifestyle like losing weight, reducing stress and exercising regularly.
  • Avoid smoking and drinking alcohol.
  • High levels of liver enzymes need immediate medical attention.
  • Watch your diet and consume low-fat foods, like green leafy vegetables, fish, whole grains, nuts, etc.
  • Regularly do strengthening exercises to control your cholesterol levels.
  • Avoid drinking alcohol as it can affect your liver.
  • Focus on losing weight as it can help control cholesterol and maintain liver enzymes.
  • Practice yoga and meditation to improve liver functioning and overall health.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

Directions for Use

  • Nexred 180Mg Tab can be taken with or without food as advised by your doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication for effective results.
  • Swallow Nexred 180Mg Tab as a whole with water.
  • Do not crush, chew, or break it.

How Nexred 180Mg Tab Works

Nexred 180Mg Tab contains Bempedoic acid, which works by blocking an enzyme (ATP citrate lyase) needed for the production of cholesterol. This helps block the production of cholesterol in the liver and increases the removal of LDL cholesterol. Thereby, it helps decrease bad cholesterol in the body.
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Nexred 180Mg Tab . Please consult a doctor.

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Pregnancy

Unsafe

Nexred 180Mg Tab may harm the unborn baby. Do not take Nexred 180Mg Tab if you are pregnant, think you may be pregnant or if you are trying to become pregnant. Consult the doctor immediately if you become pregnant during treatment with Nexred 180Mg Tab .

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Breast Feeding

Unsafe

It is unknown if Bempedoic acid passes into breast milk. Do not take Nexred 180Mg Tab if you are breastfeeding.

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Driving

Safe if prescribed

Nexred 180Mg Tab has little or no influence on your ability to drive.

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Liver

Consult your doctor

It is not known if Nexred 180Mg Tab is safe and effective in people with liver disease. Please consult the doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

It is not known if Nexred 180Mg Tab is safe and effective in people with kidney disease, including end-stage kidney disease, who are on dialysis. Please consult the doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Nexred 180Mg Tab is not recommended for children below 18 years as the safety and effectiveness have not been established.

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Heart

Caution

Take Nexred 180Mg Tab with caution, especially if you have a history of heart disease. Inform your doctor before receiving the Nexred 180Mg Tab if you have a history of heart diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

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Geriatrics

Caution

Nexred 180Mg Tab can be used in the elderly when prescribed by a doctor. If you have any concerns about using Nexred 180Mg Tab , please consult a doctor.

What if I have taken an overdose of Nexred 180Mg Tab

Do not take more than the prescribed dose. Using more medication will not improve your symptoms; instead, they may cause poisoning or serious side effects. If you suspect that you may have overdosed of Nexred 180Mg Tab or observe any side effects, please go to the emergency department of the closest hospital or nursing home.

Diet & Lifestyle Advise

  • Follow a cholesterol-lowering diet.
  • Exercise regularly. It helps in maintaining proper weight and lowers cholesterol.
  • Limit salt and sugar intake.
  • Avoid smoking and alcohol consumption.
  • Choose healthy fats and cut down on trans fats.
  • Include omega-3 fatty acids, fibre-rich food, fruits and vegetables.
  • Get active by engaging in any physical activity, such as swimming, brisk walking, or jogging. Take stairs instead of elevators/lifts.
health query

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How Soon It Starts Working

  • The time required for Nexred 180Mg Tab to start to work: Nexred 180Mg Tab ideally shows its action within 3.5 hours after administration. 
  • The time for which the effects of Nexred 180Mg Tab last: The effect of Nexred 180Mg Tab lasts for 15 to 24 hours.

What if you forget to take Nexred 180Mg Tab

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose.

Storage

• Store in a cool and dry place away from sunlight.• Keep Nexred 180Mg Tab out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Do not take Nexred 180Mg Tab if you are allergic to any of its components or if you are pregnant or breastfeeding.
  • Inform the doctor if you have/had gout, severe kidney or liver problems, or tendon problems.
  • Consult the doctor immediately if you become pregnant during treatment with Nexred 180Mg Tab .
  • Seek medical attention if you experience symptoms of gout (tender joints, joint redness, severe foot pain, especially in the toe joint, warm joints, and swelling), tendon problems (pain, swelling, tears and inflammation of tendons), or tendon rupture (hear or feel a snap or pop in a tendon area, bruising right after an injury in a tendon area, or are unable to move the affected area or put weight on the affected area).

Drug-Drug Interactions

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Drug-Drug Interactions: Inform the doctor if you are taking statins (atorvastatin, fluvastatin, pitavastatin, pravastatin, rosuvastatin, simvastatin), medicine used to treat pulmonary artery hypertension (bosentan), anti-hypertensive (fimasartan), or medicines used to treat hepatitis C (asunaprevir, glecaprevir, grazoprevir, voxilaprevir).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Inform the doctor if you have gout/hyperuricemia (high uric acid levels), tendon problems, or severe kidney or liver problems.

Bempedoic acidBudesonide
Severe
Bempedoic acidOfloxacin
Severe

Drug-Drug Interactions

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Bempedoic acidBudesonide
Severe
How does the drug interact with Nexred 180 mg Tablet:
Co-administration of Budesonide with Nexred 180 mg Tablet can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although taking Budesonide with Nexred 180 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience pain, swelling, or inflammation in joints consult a doctor immediately. Exercising or using the injured area should also be avoided. Do not discontinue the medications without a doctor's advice.
Bempedoic acidOfloxacin
Severe
How does the drug interact with Nexred 180 mg Tablet:
Co-administration of Nexred 180 mg Tablet and Ofloxacin can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although taking Nexred 180 mg Tablet and Ofloxacin together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have pain, swelling, or inflammation in a muscle location such as the back of the ankle, shoulder, or biceps. Exercising or using the injured area should also be avoided. Do not discontinue any medications without consulting a doctor.
Bempedoic acidFludrocortisone
Severe
How does the drug interact with Nexred 180 mg Tablet:
Taking Nexred 180 mg Tablet with Fludrocortisone can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Nexred 180 mg Tablet can be taken with Fludrocortisone if prescribed by the doctor. However, if you experience pain, swelling, or inflammation in joints, consult a doctor. Exercising or using the injured area should also be avoided Do not discontinue any medications without consulting a doctor.
Bempedoic acidHydrocortisone
Severe
How does the drug interact with Nexred 180 mg Tablet:
Co-administration of Nexred 180 mg Tablet with Hydrocortisone can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Nexred 180 mg Tablet can be taken with Hydrocortisone if prescribed by the doctor. However, if you experience pain, swelling, or inflammation of joints consult a doctor. Exercise and using the impacted area should both be avoided. Do not discontinue any medications without a doctor's advice.
Bempedoic acidCortisone
Severe
How does the drug interact with Nexred 180 mg Tablet:
Co-administration of Nexred 180 mg Tablet and Cortisone can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Nexred 180 mg Tablet can be taken with Cortisone if prescribed by the doctor. However, if you experience pain, inflammation, or swelling of joints, consult a doctor. Do not discontinue any medications without a doctor's advice.
Bempedoic acidEnoxacin
Severe
How does the drug interact with Nexred 180 mg Tablet:
Co-administration of Nexred 180 mg Tablet and enoxacin can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Nexred 180 mg Tablet can be taken with Enoxacin if prescribed by the doctor. However, if you experience pain, inflammation, or swelling in joints consult a doctor. Exercise and using the impacted area should both be avoided. Do not discontinue any medications without a doctor's advice.
Bempedoic acidSimvastatin
Severe
How does the drug interact with Nexred 180 mg Tablet:
Using Simvastatin together with Nexred 180 mg Tablet can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Co-administration of Simvastatin and Nexred 180 mg Tablet can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any muscle pain, weakness, fever, dark urine, joint pain or swelling, vomiting, and yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
Bempedoic acidMethylprednisolone
Severe
How does the drug interact with Nexred 180 mg Tablet:
Co-administration of Nexred 180 mg Tablet with Methylprednisolone can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Nexred 180 mg Tablet can be taken with Methylprednisolone if prescribed by the doctor. However, if you experience pain, swelling, or inflammation of joints, consult a doctor. Exercise and using the impacted area should both be avoided. Do not discontinue any medications without a doctor's advice.
Bempedoic acidCiprofloxacin
Severe
How does the drug interact with Nexred 180 mg Tablet:
Taking Nexred 180 mg Tablet with Ciprofloxacin may can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Nexred 180 mg Tablet can be taken with Ciprofloxacin if prescribed by the doctor. However, if you experience pain, inflammation, or swelling in joints, consult a doctor immediately. Exercise and using the affected area should be avoided. Do not discontinue any medications without a doctor's advice.
Bempedoic acidTriamcinolone
Severe
How does the drug interact with Nexred 180 mg Tablet:
Taking Nexred 180 mg Tablet with Triamcinolone can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction between Nexred 180 mg Tablet and triamcinolone, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience pain, swelling, or inflammation of a tendon area such as the back of the ankle, shoulder, or biceps, stop taking Nexred 180 mg Tablet and consult a doctor. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[MISCELLANEOUS]

FAQs

Nexred 180Mg Tab is used to decrease bad cholesterol in patients with heart disease or familial heterozygous hypercholesterolemia (an inherited condition in which cholesterol cannot be removed from the body normally).
Nexred 180Mg Tab works by blocking the production of cholesterol in the liver. Thereby, it helps treat high cholesterol.
Do not discontinue Nexred 180Mg Tab without consulting your doctor, as it could lead to a rise in cholesterol. To get effective results, continue taking Nexred 180Mg Tab for as long as prescribed. Do not hesitate to speak with your doctor if you experience any difficulty while taking Nexred 180Mg Tab .
Tendon problems may happen in people taking Nexred 180Mg Tab . Consult the doctor if you experience pain, swelling, inflammation and tears of tendons, including Achilles (back of ankle), arm and shoulder. The risk of tendon problems may be increased if you are above 60 years of age, have renal problems, have had tendon problems or are taking antibiotics or corticosteroids.
Nexred 180Mg Tab can sometimes cause tiredness. Although it's not a common side effect, some people may feel fatigued while taking it. If you're experiencing this, talk to your doctor. They can help determine if it's related to the medication and recommend what to do.
Nexred 180Mg Tab can sometimes affect the liver. While it's generally safe, some people may have slightly elevated liver enzymes. These usually go back to normal on their own. If you notice any signs of liver problems, like yellowing of the skin or dark urine, talk to your doctor right away.
Your doctor may not prescribe Nexred 180Mg Tab if you have a history of tendon problems, severe liver problems, or if you're pregnant or breastfeeding. It can also interact with certain other medications. If you have any of these conditions, talk to your doctor before starting Nexred 180Mg Tab .
Take it with food or between meals or as advised by the doctor. Swallow the medicine as a whole with a glass of water; do not chew or break it.
LDL cholesterol is often called "bad cholesterol" because it can clog your arteries. This can make it harder for blood to reach your heart, increasing your risk of heart problems.
HDL cholesterol is often called "good cholesterol" because it helps clear out bad cholesterol. Higher levels of HDL can be good for your heart health. But it's important to manage both good and bad cholesterol for a healthy heart.
The only way to know whether you have high cholesterol is to get your cholesterol checked. Your health professional can do a simple blood test. This is called a lipid profile.
A healthy level of total cholesterol is below 5mmol/L. HDL (good cholesterol) is above 1.0mmol/L for men or above 1.2mmol/L for women. non-HDL (bad cholesterol) is below 4mmol/L.
High cholesterol can increase your risk of heart problems. It can build up in your arteries and cause problems like heart attacks. If you have symptoms like chest pain, shortness of breath, or fatigue, see a doctor. They can check your cholesterol and recommend treatment.
Lifestyle changes can help Nexred 180Mg Tab work better. Eat healthy, exercise regularly, maintain a healthy weight, quit smoking, limit alcohol, and manage stress. These changes can help lower your cholesterol and reduce your risk of heart problems.
No, you should not stop taking Nexred 180Mg Tab without consulting your doctor. High cholesterol is a chronic condition, and you may need to continue taking medication to maintain healthy cholesterol levels.
While Nexred 180Mg Tab is generally well-tolerated, some people may experience side effects such as muscle pain, joint pain, fatigue, or digestive issues. If you experience any adverse effects, talk to your doctor.
Yes, Nexred 180Mg Tab is generally safe for people with diabetes. However, it's important to monitor your blood sugar levels closely while taking this medication.
If you have mild to moderate kidney problems, you may still be able to take Nexred 180Mg Tab . However, it's important to discuss this with your doctor, as your dosage may need to be adjusted.
It typically takes 4-8 weeks for Nexred 180Mg Tab to start lowering cholesterol levels.
No, Nexred 180Mg Tab is not known to cause weight gain.
Yes, Nexred 180Mg Tab can be taken with other cholesterol-lowering medications if prescribed by the doctor.
You can lower your cholesterol by eating healthy, exercising, quitting smoking, and managing stress. Sometimes, you might also need medicine.
High cholesterol can be caused by many things, including age, family history, diet, lack of exercise, smoking, being overweight, and having conditions like diabetes or thyroid problems.
It depends on how risky you are of having heart problems. If you have a lot of things that can increase your risk, you might need to check it more often.

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Reference

  1. Electronic Medicines Compendium (EMC). Pil.11743 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. U.S. Food and Drug Administration (FDA). 211616S000Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  3. MedlinePlus. A620020 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026]Check here
  4. Bempedoic Acid [Product Information]. 2024. [Accessed on 05 Mar. 2025]Check here
  5. Daiichi Sankyo UK Limited. Nilemdo 180 mg film‑coated tablets: Summary of Product Characteristics [Internet]. UK: Datapharm Ltd.; last updated 07 Jul 2025 [Accessed on 2025 Dec 30]Check here
  6. Elani Streja, Dan A. Streja. Management of Dyslipidemia in the Elderly. NIH National Library of Medicine. National Center for Biotechnology Information. Endotext [Internet]. September 2020. [Accessed on 4th August 2022]Check here
  7. Central Drugs Standard Control Organization (CDSCO). Drugs: Approved Drugs / Vaccines / r-DNA / Blood Products [Internet]. Government of India; [Accessed on 2025 Dec 30]Check here

Country of origin

India

Manufacturer/Marketer address

Dr. Reddy'S Laboratories Ltd., 8-2-337, Road No. 3, Banjara Hills, Hyderabad, Telangana 500034, India
Other Info - NEX0362
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