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Nicoduce 48mg Injection is mainly used to prevent or treat angina pectoris in adults who cannot take beta-blockers (blood pressure-lowering pills). Angina pectoris is a kind of chest pain due to decreased blood flow to the heart. It is a symptom of coronary artery disease.
Nicoduce 48mg Injection contains Nicorandil, that opens potassium channels present on the muscle cells within the walls of blood vessels and relaxes these muscle cells and widens blood vessels.
Some people may experience side effects such as headache, nausea, vomiting, dizziness, injection site reactions, weakness or flushing (reddening of the skin). Most of these side effects of Nicoduce 48mg Injection do not require medical attention and resolve over time. However, if the side effects persist, please consult your doctor.
Nicoduce 48mg Injection will be administered by a healthcare professional; do not self-administer. The dose of the medicine will be decided by the physician based on the severity of the disease.
If you are allergic to Nicoduce 48mg Injection or any other medicines, please tell your doctor. Inform your doctor if you are pregnant or breastfeeding. Nicoduce 48mg Injection is not recommended for children as the safety and effectiveness were not been established. It is advised to drive only if you are alert as Nicoduce 48mg Injection may cause dizziness or weakness. Avoid alcohol consumption with Nicoduce 48mg Injection as it may cause severely low blood pressure.
Nicoduce 48mg Injection is used in the treatment of angina pectoris (heart-related chest pain). The detailed use of Nicoduce 48mg Injection is as follows:
Unsafe
You are recommended to avoid consumption of alcohol with Nicoduce 48mg Injection as it may cause severely low blood pressure.
Unsafe
There is limited information on the use of Nicoduce 48mg Injection in pregnant women. Usually, it is not recommended for pregnant women. Therefore, if you are pregnant or planning pregnancy, please inform your doctor.
Consult your doctor
There is limited information on the use of Nicoduce 48mg Injection in breastfeeding mothers. Therefore, please inform your doctor if you are a breastfeeding mother.
Unsafe
Nicoduce 48mg Injection may cause dizziness or weakness in some people. Therefore, avoid driving if you feel dizzy or weak after receiving Nicoduce 48mg Injection.
Caution
Take Nicoduce 48mg Injection with caution, especially if you have a history of liver disease.
Caution
Take Nicoduce 48mg Injection with caution, especially if you have a history of kidney disease.
Unsafe
Nicoduce 48mg Injection is not recommended for children as safety and effectiveness were not established.
Caution
Take Nicoduce 48mg Injection with caution, especially if you have a history of heart disease.
Caution
Nicoduce 48mg Injection should be used with caution in elderly patients. Please consult your doctor before use.

Have a query?
The time required for Nicoduce 48mg Injection to start to work: The exact onset time of Nicoduce 48mg Injection has not been clinically established. The time for which the effects of Nicoduce 48mg Injection last: The duration of Nicoduce 48mg Injection’s effect is clinically not established.
Keep Refrigerated. Do not freeze.Prepaid payment required.
Drug-Drug Interaction: Nicoduce 48mg Injection may interact with medicines used to treat erectile dysfunction (vardenafil, sildenafil, tadalafil), drugs to treat pulmonary hypertension (riociguat), medicine to treat premature ejaculation (dapoxetine), pain reliever (aspirin), steroids (prednisolone), high blood pressure-lowering medicines (lisinopril, ramipril, losartan, valsartan, candesartan).
Drug-Food Interaction: Nicoduce 48mg Injection may interact with alcohol. Therefore, avoid alcohol intake while treatment with Nicoduce 48mg Injection as it may cause severe low blood pressure.
Drug-Disease Interaction: Avoid administration of Nicoduce 48mg Injection if you have hypotension (severe low blood pressure), low blood volume, pulmonary oedema (build-up of fluid in the lungs) or any heart problems.
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Nicoduce 48mg Injection is used to treat Angina pectoris (heart-related chest pain).
Nicoduce 48mg Injection contains Nicorandil which works by relaxing and widening blood vessels. Thereby, Nicoduce 48mg Injection reduces the workload of the heart by making it easier for the heart to pump blood around the body and does not require much oxygen. Also, Nicoduce 48mg Injection helps to prevent angina by increasing oxygen and blood supply to the heart muscle by widening coronary arteries within the heart.
Nicoduce 48mg Injection may cause headache as a common side effect, especially in the first few days of treatment. However, if the condition persists or worsens, please consult a doctor so that the dose may be reduced initially.
Nicoduce 48mg Injection is not recommended for patients with severe hypotension (low blood pressure) as it may increase the risk of worsening the condition. Therefore, inform your doctor if you have low blood pressure before taking Nicoduce 48mg Injection.
You are not recommended to take aspirin (pain reliever) with Nicoduce 48mg Injection as co-administration of these two medicines may increase the risk of ulcers or other adverse effects. However, please consult a doctor before taking other medicines with Nicoduce 48mg Injection.
You are recommended to avoid receiving Nicoduce 48mg Injection if you have hypotension (severe low blood pressure), low blood volume, pulmonary oedema (accumulation of fluid in the lungs) or any heart problems such as left ventricular failure with low filling pressure, cardiac decompensation or cardiogenic shock.
You are not recommended to take more than the prescribed dose of Nicoduce 48mg Injection as it may cause Nicoduce 48mg Injection overdose resulting in symptoms such as weakness, dizziness (signs of low blood pressure), and fast or irregular heartbeat. However, if you experience any of these symptoms while receiving Nicoduce 48mg Injection, please consult a doctor immediately.
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