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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Nifurant-SR Tablet is used to prevent and treat bacterial infections like urinary tract infections (UTIs), including Bladder Infection (cystitis). It is also used to treat kidney infections. It contains Nitrofurantoin, which kills bacteria by entering their cells and destroying their genetic material. As a result, it is effective against bacterial infections. It may cause common side effects like nausea, vomiting, diarrhoea, loss of appetite and headaches. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Manufacturer/Marketer :

Trumac Healthcare

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Nifurant-SR Tablet

Nifurant-SR Tablet belongs to a group of antibacterial or antibiotics. Nifurant-SR Tablet is used to prevent and treat bacterial infections like urinary tract infections (UTIs), including Bladder Infection (cystitis). Besides this, it is also used in to treat kidney infections. A urine infection is often called a urinary tract infection (or simply, UTI). Most urine infections are caused by germs (bacteria). They are usually easily treated with a short course of an antibacterial medicine such as Nifurant-SR Tablet . Occasionally, longer-term treatment is needed to prevent infections from coming back.

Nifurant-SR Tablet contains Nitrofurantoin. When you take Nifurant-SR Tablet , your body immediately filters it out of your blood and into your urine. If you have a urinary tract infection, this indicates that the treatment is concentrated at the site of illness. On the other hand, nitrofurantoin kills bacteria by entering their cells and destroying their genetic material. As a result, it is effective against bacterial infections.

You should take Nifurant-SR Tablet only if your doctor has prescribed you. Most bacterial infections get treated within one week, while some conditions might take longer. If you stop taking it too early, the infection may return or worsen. So, it would be best if you tried to complete the prescribed dosage. During the treatment with Nifurant-SR Tablet , you may observe some common side effects like feeling sick (nausea), vomiting, diarrhoea, loss of appetite and headaches. But these side effects are usually in the initial phase and then resolve after some time. However, if these side effects persist, let your doctor know about this if you notice any sudden wheeziness, tightness in the chest or throat, difficulty in breathing, swelling of the eyelids, face or lips, rash or itching (especially affecting your whole body) STOP TAKING your medicine and go to a doctor immediately.

Nifurant-SR Tablet is generally well-tolerated among adults and children. Do not take Nifurant-SR Tablet if you are allergic to amoxicillin, penicillin antibiotics, have liver/kidney problems, and had any vaccinations. If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking Nifurant-SR Tablet . As far as it is known, Nifurant-SR Tablet may be used in pregnancy. However, it should not be used during labour or delivery because there is a possibility that use at this stage may affect the baby. If you want to breastfeed, please consult your doctor first.

Uses of Nifurant-SR Tablet

Nifurant-SR Tablet is used in the treatment of bacterial infections like urinary tract infections (UTIs), including bladder Infection, cystitis, and kidney infections.The detailed uses of Nifurant-SR Tablet are as follows:<br/> • Urinary tract infections (UTIs): Nifurant-SR Tablet treats urinary tract infections caused by bacteria like E. coli, by stopping the growth of bacteria, helping to relieve symptoms and clear the infection.<br/> • Bladder Infection: Nifurant-SR Tablet treats bladder infections by killing the bacteria that cause the infection, helping to relieve symptoms like burning during urination and frequent urination.<br/> • Cystitis: Nifurant-SR Tablet is commonly used to treat cystitis, which is inflammation of the bladder often caused by bacterial infections. It helps to alleviate symptoms and clears the infection.<br/> • Kidney infections: Nifurant-SR Tablet may also provide relief from the symptoms due to kidney infections that are often caused by bacteria.<br/>

Directions for Use

  • Nifurant-SR Tablet can be taken with or without food or as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Nifurant-SR Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it. 

Medicinal Benefits

Nifurant-SR Tablet contains antibiotic Nitrofurantoin, which helps in treating and preventing a wide range of bacterial infections like urinary tract infections (UTIs), including Bladder Infection (cystitis) and kidney infections caused by most susceptible bacteria (susceptible strains of Escherichia coli, enterococci, staphylococci, Citrobacter, Klebsiella and Enterobacter). It is bactericidal in nature and works by killing bacteria that cause infections by preventing the formation of the cell wall required for living. It also inhibits the repair of bacterial cells. Altogether it kills the bacteria.

How Nifurant-SR Tablet Works

Nifurant-SR Tablet contains Nitrofurantoin. When you take Nifurant-SR Tablet , your body immediately filters it out of your blood and into your urine. If you have a urinary tract infection, this indicates that the treatment is concentrated at the site of illness. On the other hand, nitrofurantoin kills bacteria by entering their cells and destroying their genetic material. As a result, it is effective against bacterial infections.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Nifurant-SR Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

What if I have taken an overdose of Nifurant-SR Tablet

Do not take more than the prescribed dose of Nifurant-SR Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Nifurant-SR Tablet if you are allergic or have had a severe reaction to Nifurant-SR Tablet or any other medicines in the past, or inherited conditions such as porphyria (a blood disorder), glucose-6-phosphate dehydrogenase (G6PD) deficiency,  severe kidney disease, diabetes, or any illness-causing severe weakness, anaemia or vitamin B deficiency. Inform your doctor if you have or have ever had a kidney, heart, or lung transplant, a joint or tendon disorder such as rheumatoid arthritis (an autoimmune disorder of joints causing pain, swelling, and loss of function), seizures (fits), epilepsy or if you participate in regular physical activity. Taking Nifurant-SR Tablet may worsen muscle weakness in people with myasthenia gravis (a nervous system disorder that causes muscle weakness) and cause severe difficulty breathing or death. Grapefruit, a calcium-rich food, should be avoided along with Nifurant-SR Tablet . And also, exposure to sunlight should be avoided while taking Nifurant-SR Tablet as it may cause increased phototoxicity or photosensitivity. Patients with epilepsy and irregular heartbeat (QT prolongation) should tell their doctor before taking Nifurant-SR Tablet .

Drug-Drug Interactions

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NitrofurantoinRopivacaine
Severe

Drug-Drug Interactions

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NitrofurantoinRopivacaine
Severe
How does the drug interact with Nifurant-SR Tablet:
Combining Nifurant-SR Tablet with Ropivacaine can increase the risk of methemoglobinemia (a condition in which the iron in the hemoglobin molecule (the red blood pigment) is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although there is a possible interaction between Nifurant-SR Tablet and Ropivacaine, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms, it's important to contact your doctor right away. These symptoms include gray discoloration of the skin, feeling sick, having a headache, feeling dizzy or lightheaded, feeling tired, having trouble breathing, a fast or irregular heartbeat, and feeling anxious or confused. Don't hesitate to reach out to a doctor if you experience any of these. Do not stop using any medications without a doctor's advice.
How does the drug interact with Nifurant-SR Tablet:
Coadministration of Nifurant-SR Tablet with leflunomide can increase the risk or severity of liver problems.

How to manage the interaction:
Although there is an interaction between Nifurant-SR Tablet and leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NitrofurantoinMepivacaine
Severe
How does the drug interact with Nifurant-SR Tablet:
Combining Nifurant-SR Tablet with Mepivacaine can increase the risk of methemoglobinemia (a condition in which the iron in the hemoglobin molecule is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking Nifurant-SR Tablet and Mepivacaine together can cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms, it's important to contact a doctor right away: gray skin color, feeling sick, headache, feeling dizzy or lightheaded, tiredness, trouble breathing, fast or shallow breathing, a fast heartbeat, feeling your heart pounding, feeling anxious or confused. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nifurant-SR Tablet:
Taking Bupivacaine and Nifurant-SR Tablet may cause methemoglobinemia, (a condition in which the iron in the hemoglobin molecule -the red blood pigment is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Taking bupivacaine and Nifurant-SR Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
NitrofurantoinTetracaine
Severe
How does the drug interact with Nifurant-SR Tablet:
Combining Nifurant-SR Tablet with Tetracaine can increase the risk of methemoglobinemia (a condition in which the iron in the hemoglobin molecule is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking Nifurant-SR Tablet and Tetracaine together can cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms, it's important to contact a doctor right away if you experience your skin turning gray, feeling sick to your stomach, having a headache, feeling dizzy or lightheaded, being very tired, having trouble breathing, breathing quickly or not deeply enough, a fast heartbeat, feeling your heart pounding, feeling anxious or confused. Do not stop using any medications without talking to a doctor.
NitrofurantoinBCG vaccine
Severe
How does the drug interact with Nifurant-SR Tablet:
When BCG vaccine is used with Nifurant-SR Tablet, its effectiveness may be reduced.

How to manage the interaction:
Taking Nifurant-SR Tablet with BCG vaccine together can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without a doctor's advice. Do not stop using any medications without consulting a doctor.
Severe
How does the drug interact with Nifurant-SR Tablet:
Combining Nifurant-SR Tablet with Procaine can increase the risk of methemoglobinemia (a condition in which the iron in the hemoglobin molecule (the red blood pigment) is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Taking Nifurant-SR Tablet with Procaine together can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms, it's important to contact a doctor right away. These symptoms include gray skin color, feeling sick, having a headache, feeling dizzy or lightheaded, feeling tired, having trouble breathing, a fast or irregular heartbeat, and feeling anxious or confused. Do not discontinue any medications without consulting a doctor.
NitrofurantoinSodium nitrite
Severe
How does the drug interact with Nifurant-SR Tablet:
Combining Nifurant-SR Tablet with Sodium nitrite can increase the risk of methemoglobinemia (a condition in which the iron in the hemoglobin molecule is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Taking Nifurant-SR Tablet with Sodium nitrite together can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms, it's important to contact a doctor right away if you experience gray skin color, nausea, a headache, feeling dizzy or lightheaded, being tired, having trouble breathing, having a fast or irregular heartbeat, and feeling anxious or confused. Do not discontinue any medications without consulting a doctor.
NitrofurantoinMipomersen
Severe
How does the drug interact with Nifurant-SR Tablet:
Coadministration of Mipomersen with Nifurant-SR Tablet may increase the risk of liver problems.

How to manage the interaction:
There may be a possibility of interaction between Nifurant-SR Tablet and Mipomersen, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away. These symptoms include liver problems, fever, rash, itching, loss of appetite, feeling sick, throwing up, feeling tired, feeling unwell, pain in the upper right side of your belly, dark urine, yellowing of the skin or eyes, chills, joint pain, swelling, bruising, not wanting to eat, belly pain, liver damage, bleeding, or throwing up. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nifurant-SR Tablet:
Coadministration of Nifurant-SR Tablet with Teriflunomide can increase the risk or severity of liver damage.

How to manage the interaction:
Taking Nifurant-SR Tablet with Teriflunomide together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • It would be best to take probiotics after taking the full course of Nifurant-SR Tablet to restore some healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.

  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. Thus fibre foods may help restore healthy gut bacteria after taking a course of antibiotics. Whole grains like whole-grain bread, and brown rice, should be included in your diet.

  • Avoid taking too much calcium enriched foods and drinks as it might affect the working of Nifurant-SR Tablet .

  • Avoid intake of alcoholic beverages with Nifurant-SR Tablet as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Nifurant-SR Tablet in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS
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Alcohol

Consult your doctor

No reported interaction with Nifurant-SR Tablet . But, It is best to avoid alcohol while taking medication.

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Pregnancy

Caution

Nifurant-SR Tablet can be safely taken by pregnant women if prescribed by the doctor. But do not take nitrofurantoin during labour and childbirth, as there's a chance that it can affect the baby's blood.

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Breast Feeding

Consult your doctor

Nifurant-SR Tablet is excreted in breast milk. Caution should be exercised, and it is advisable to consult a doctor before using it.

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Driving

Unsafe

Nifurant-SR Tablet may cause dizziness and drowsiness, and the patient should not drive or operate machinery.

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Liver

Consult your doctor

If you have or had a history or evidence of any liver-related diseases, please consult the doctor before taking medicine.

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Kidney

Consult your doctor

Nifurant-SR Tablet is contraindicated in patients with renal dysfunction and patients with an eGFR of less than 45 ml/minute. It is advisable to consult a doctor before using it.

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Children

Safe if prescribed

Nifurant-SR Tablet can be given to children but under child specialist medical supervision. Nifurant-SR Tablet is prescribed to the children to treat complicated urinary tract infections.

Have a query?

FAQs

Nifurant-SR Tablet is used to treat bacterial infections like urinary tract infections (UTIs), including bladder infections, cystitis and kidney infections.

Nifurant-SR Tablet kills bacteria by entering their cells and destroying their genetic material. As a result, it is effective against bacterial infections.

Nifurant-SR Tablet belongs to the class of penicillin antibiotic. Nifurant-SR Tablet is a broad-spectrum antibiotic effective against a wide range of bacteria. On the other hand, penicillin is a narrow-spectrum antibiotic effective against less number of bacteria.

No. You should complete the full course of Nifurant-SR Tablet as prescribed by your doctor. After completing the full course of Nifurant-SR Tablet will work. It is important that you take Nifurant-SR Tablet at the right dose, right times and for the right numbers of days.

Nifurant-SR Tablet does not work against viral infection. So, treating common cold and cough should not be taken.

Nifurant-SR Tablet makes your skin sensitive to sunlight, known as photosensitivity. So, prolonged exposure to sunlight or ultraviolet light should be avoided. In case of emergency, you should always wear sunscreen before going out.

No, Nifurant-SR Tablet should be taken in the dose and duration as advised by the doctor. If you take it in more than the recommended dose, it might cause unpleasant side effects. If you think your symptoms are not improving, please consult your doctor.

Stay hydrated by drinking at least six glasses of water or other fluids. Keep your underwear clean, and use underwear made of cotton to avoid spreading infection. Always keep your bladder empty as much as possible by peeing regularly. Your doctor may prescribe cranberry juice with antibiotics to treat urinary tract infections.

Always follow your pharmacist's or doctor's advice and the instructions that come with your medicine.

Your dose of Nifurant-SR Tablet depends on whether it's to treat or prevent a medical condition, your age, and how bad the infection is.

Nifurant-SR Tablet can cause acute or chronic liver injury. So, inform your doctor before prescribing Nifurant-SR Tablet about your medical condition. Your doctor will monitor your liver with blood tests and adjust the treatment if necessary.

Never take an extra dose to make up for a forgotten one. It may lead to more prone to more adverse events.

In some cases, Nifurant-SR Tablet may cause blurred vision. It may be severe and, in some instances, permanent. So, seek medical attention immediately if you observe any symptoms related to this.

In some instances, Nifurant-SR Tablet may cause neurological adverse effects, including headache, drowsiness, vertigo, dizziness, nystagmus (involuntary eye movement), intracranial hypertension, and peripheral neuropathy.

No, Nifurant-SR Tablet is not a sleeping pill; it is an antibiotic medication. However, it can make you feel dizzy or sleepy.

Nifurant-SR Tablet begins working within a few hours, but it should be taken for 5 to 7 days to fully treat an infection.

No, Nifurant-SR Tablet is not intended to treat anxiety. It is an antibiotic medication.

Acidic foods, spicy foods, alcohol, and caffeine can all increase UTI symptoms and nitrofurantoin side effects, so you may want to avoid these while taking the medication.

Even if you feel better, continue taking nitrofurantoin until the end of the prescription. If you stop taking nitrofurantoin too soon or skip doses, your infection may become more difficult to cure, and the bacteria may develop antibiotic resistance.

Nifurant-SR Tablet might cause weight loss as taking it makes you feel less or not hungry (loss of appetite). However, it varies from person to person.

Swallow the tablet whole with a drink of water. Do not chew or break them. Take Nifurant-SR Tablet with or after a meal or snack. This helps your body absorb the medicine, as well as helping to prevent stomach upset.

Country of origin

India

Manufacturer/Marketer address

Plot 231, Phase-1, Industrial Area, Panchkula, Haryana (134113)
Other Info - NIF0054

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