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compositionComposition:NIMESULIDE-100MG
prescription
Prescription Medicine
info
Nise 100 Tablet 15's
Nise 100 Tablet 15's
Nise 100 Tablet 15's
Nise 100 Tablet 15's

Nise 100 Tablet is used to treat pain and dysmenorrhea (painful periods or menstrual cramps). Besides this, it is also used to treat dental pain that can result from damage to the tooth nerve, infection, decay, extraction, or injury. It contains Nimesulide, which works by blocking the effects of a chemical called prostaglandin, which is responsible for inducing pain and inflammation in the body. It may cause common side effects like nausea, diarrhoea, changes in liver enzymes, and vomiting. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

NIMESULIDE-100MG

Manufacturer/Marketer :

Dr Reddy's Laboratories Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Nise 100 Tablet

Nise 100 Tablet is used to treat pain and dysmenorrhea (painful periods or menstrual cramps). They are also used to treat dental pain, which can result from damage to the tooth nerve, infection, decay, extraction, or injury.

Nise 100 Tablet contains Nimesulide, which works by blocking the effects of a chemical called prostaglandin, which is responsible for inducing pain and inflammation in the body.

Like all medicines, Nise 100 Tablet may cause common side effects like nausea, diarrhoea, changes in liver enzymes, and vomiting. Most of these side effects do not require medical attention and resolve gradually over time. However, if the side effects persist or worsen, consult a doctor.

Do not take Nise 100 Tablet if you are allergic to any of its components. It is not recommended for use in children, people with liver disease, heart disease, or gastric ulcers/bleeding problems. Nise 100 Tablet may affect fertility and can be passed in milk. The use of Nise 100 Tablet should be avoided in pregnant and nursing mothers.

Uses of Nise 100 Tablet

Nise 100 Tablet used in the treatment of pain relief. The detailed uses of Nise 100 Tablet are as follows: 

  • Pain Relief: Nise 100 Tablet provides relief from mild to moderate pain, such as headaches, toothaches, and joint pain.
  • Anti-inflammatory: Nise 100 Tablet reduces inflammation and swelling in conditions like arthritis and muscle injuries, relieving pain and discomfort.
  • Fever Reduction: Nise 100 Tablet also helps to reduce fever, making you feel better and more comfortable.
  • Menstrual Pain: Nise 100 Tablet is often prescribed for alleviating cramps and discomfort associated with menstruation.
  • Post-operative Pain: Doctors may recommend Nise 100 Tablet to manage pain following surgical procedures and aid recovery.

Key Benefits

Nise 100 Tablet provides effective relief from pain, swelling, and inflammation, helping you regain comfort and move more easily throughout the day. By targeting both pain and inflammatory processes, this medicine offers several key benefits:

  • Rapid Pain Relief: Nise 100 Tablet is absorbed quickly by the body, allowing you to experience relief from discomfort and pain shortly after taking it.
    Reduced Inflammation: By targeting the root causes of swelling, this medication helps lower inflammation in muscles and joints, paving the way for a faster and smoother recovery.
  • Restored Mobility: Easing severe joint and muscle pain helps you move more freely and comfortably, making it easier to perform your daily activities without constant discomfort.

Directions for Use

  • Take Nise 100 Tablet exactly as prescribed by your doctor, using the lowest effective dose for the shortest time needed.
  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break any extended-release tablet or granule formulation. Standard immediate-release tablets may be split if advised by your doctor or pharmacist.
  • Always take this medicine after a meal to reduce the risk of an upset stomach.
    Never take more than the recommended dose, and do not take it for longer than 15 days in a row.
    Talk to your doctor or pharmacist if you are unsure about your schedule or how to take your dose.
     

How Nise 100 Tablet Works

Nise 100 Tablet works by blocking the action of specific chemical messengers in the body known as prostaglandins. These chemicals are naturally released when you experience an injury or inflammation, and they are responsible for causing pain, swelling, and fever. By stopping these messengers from being produced, Nise 100 Tablet effectively turns down the pain signals and reduces swelling, helping you feel more comfortable.
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Alcohol

Unsafe

Taking Nise 100 Tablet with alcohol may cause dizziness or drowsiness. So, avoid or limit the intake of alcoholic beverages with Nise 100 Tablet .

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Pregnancy

Unsafe

Use of Nise 100 Tablet during pregnancy is not recommended, especially during the last 3 months of pregnancy, as it may harm the unborn baby.

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Breast Feeding

Unsafe

Use of Nise 100 Tablet during breastfeeding is not recommended as it may pass through the milk and harm the baby.

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Driving

Caution

Nise 100 Tablet may cause dizziness, sleepiness, and drowsiness. Drive only if you are alert.

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Liver

Unsafe

Nise 100 Tablet can cause hepatotoxicity (liver damage). So, it is not recommended for people with liver disease/impairment.

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Kidney

Caution

Nise 100 Tablet to be taken with caution, especially if you have a history of kidney disease. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Nise 100 Tablet is not recommended for children below 12 years of age. It may cause kidney problems in children and adolescents who are dehydrated.

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Heart

Unsafe

Nise 100 Tablet should be avoided in cardiac patients as it can lead to serious cardiovascular risks

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Geriatrics

Caution

Nise 100 Tablet should be given with caution in geriatrics due to increased risk of side effects. If you have any concerns about using Nise 100 Tablet , please consult a doctor.

What if I have taken an overdose of Nise 100 Tablet

Do not take more than the prescribed dose of Nise 100 Tablet as it may cause kidney problems. If you suspect you have taken an overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Protect your stomach: Avoid consuming spicy, highly acidic, or fried foods while taking this medicine, as they can worsen stomach irritation.
     
  • Stay hydrated: Drink plenty of water throughout the day to help your kidneys process the medication safely and efficiently.
  • Avoid alcohol completely: Do not drink alcohol while taking Nise 100 Tablet , as the combination severely increases your risk of liver damage and stomach bleeding.
  • Rest and gentle movement: If you are treating joint pain or muscle strains, balance rest with gentle stretching rather than heavy exercise to prevent further injury while the pain is masked.
     

Health Queries

I have a recurring fever with chills, sweating, and joint pain in my wrist, back, and ankles, and taking a Nise tablet only provided temporary relief; what medication should I take?

Vikas Singh

Vikas Singh

M Pharmacy

Your symptoms of recurring fever, chills, sweating, and joint pain suggest an underlying infection such as malaria, dengue, chikungunya, or a bacterial illness. Nise (nimesulide) only temporarily masks the pain and fever but will not cure the underlying cause. Self-medicating with stronger drugs is unsafe and can be harmful. I strongly advise you to consult a healthcare professional immediately. You need diagnostic blood tests (like a complete blood count, malaria, or dengue test) to identify the specific cause. Once diagnosed, a doctor will prescribe the appropriate targeted treatment, such as antibiotics or antimalarials. Please stay well-hydrated and rest until you see a doctor.

I have been suffering from a cold and fever since yesterday morning and have already taken Wikoryl and Nise tablets; what other medicine should I take?

G.santoshini Reddy

G.santoshini Reddy

M Pharmacy (Pharmaceutics)

Please do not take any more medicines. Wikoryl already contains paracetamol, an antihistamine, and a decongestant, while Nise contains nimesulide, a strong painkiller. Combining these two medications already puts you at risk of therapeutic duplication, which can strain your liver and kidneys. Adding more self-prescribed drugs can be dangerous. Instead, rest, stay hydrated with warm fluids, and try steam inhalation for nasal congestion. If your fever and cold do not improve within 48 hours, or if you develop new symptoms like breathlessness, please consult a doctor immediately for a proper evaluation and safe prescription.

I developed red rashes all over my body, especially on my hands and legs, after taking Nise, paracetamol, an antibiotic, and cetirizine for a fever. What medicine should I take to treat these rashes?

G.santoshini Reddy

G.santoshini Reddy

M Pharmacy (Pharmaceutics)

You are likely experiencing an allergic drug reaction to one of the medications you recently took, most commonly the antibiotic or Nise. Please stop taking Nise, paracetamol, and the antibiotic immediately. Do not attempt to self-medicate with more drugs to treat this rash. Since the rash developed despite taking cetirizine (an antihistamine), you need a professional medical evaluation. Please visit a doctor or an emergency clinic immediately so they can prescribe safer alternatives and proper treatment. Seek urgent emergency care if you experience any difficulty breathing, dizziness, or swelling of your face, lips, or throat.

I have been suffering from a fever for 8 days, which stays at 102°F and only drops to 100°F after taking Crocin. My Widal and malaria (MP) tests are negative. Last night I took a Nise tablet, which dropped my temperature to 97.8°F but caused severe weakness, and now it is back up to 99°F. What medicine should I take to properly treat this persistent fever and weakness?

G.santoshini Reddy

G.santoshini Reddy

M Pharmacy (Pharmaceutics)

Please consult a doctor immediately and stop taking Nise (Nimesulide), as it can cause a sudden, unsafe drop in temperature and severe weakness. An 8-day persistent fever requires proper medical evaluation. Since Widal and malaria tests are negative, your doctor may recommend further tests like a Complete Blood Count (CBC), Dengue test, or Urine Routine to find the exact cause. Avoid self-medicating with strong painkillers or antibiotics. For now, stick to Crocin (Paracetamol) only when your temperature exceeds 100°F. Use tepid water sponging to lower fever safely, and drink plenty of fluids (like ORS or coconut water) to recover from the weakness. Please seek immediate medical attention.

I work on computers all day, wear glasses, and suffer from severe eye pain. I have been taking Nise painkillers for the past two years; what appropriate medicine or eye drops should I use instead?

G.santoshini Reddy

G.santoshini Reddy

M Pharmacy (Pharmaceutics)

Please stop taking Nise immediately. Daily use of this painkiller for two years is highly unsafe and can cause serious kidney, liver, and stomach damage. Your severe eye pain is likely due to digital eye strain, dry eyes, or an outdated glasses prescription.Instead of oral painkillers, use over-the-counter lubricating eye drops (like Carboxymethylcellulose 0.5%) 4 times a day to relieve dryness. Follow the 20-20-20 rule: every 20 minutes, look at something 20 feet away for 20 seconds.Most importantly, please consult an ophthalmologist immediately for a comprehensive eye exam to rule out serious conditions and update your prescription.

Have a query?

How Soon It Starts Working

  • The time required for Nise 100 Tablet to start to work: The time required for Nise 100 Tablet to start to work is 2 to 3 hours after administration.
  • The time for which the effects of Nise 100 Tablet last: The duration of action for Nise 100 Tablet is unknown.

What if you forget to take Nise 100 Tablet

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and take the next dose at the regular time.

Storage

• Store Nise 100 Tablet tablets in their original packaging at room temperature, ideally between 15°C and 30°C (59°F to 86°F). • Keep the medicine in a dry place away from direct sunlight, moisture, and extreme heat.

Drug Warnings

  • Limit treatment duration: Never take this medication for more than 15 consecutive days to protect your liver from damage.
  • Check other pain relievers: Do not take Nise 100 Tablet alongside other non-steroidal anti-inflammatory drugs (NSAIDs) or paracetamol, as this can lead to accidental overdose and severe organ damage.
  • Watch for fever: If you develop a fever or flu-like symptoms while taking this medicine, stop using it immediately and contact your doctor, as this can be an early sign of a liver reaction.
  • Be cautious when driving: This medicine may cause dizziness or sleepiness in some people. Avoid driving or operating machinery until you know how it affects you.
  • Check package integrity: Always inspect the blister pack before use; do not take any tablet if the foil is broken, torn, or shows signs of tampering.

Drug-Drug Interactions

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Drug-Drug Interactions

  • Blood thinners (like warfarin): May significantly increase your risk of severe stomach bleeding.
  • Other pain relievers: Taking these together increases the risk of severe liver damage and stomach ulcers.
  • Water pills (diuretics) and blood pressure medicines: Nise 100 Tablet can reduce their effectiveness and increase the risk of kidney problems.
  • Lithium: May raise lithium levels in your blood, increasing the risk of lithium toxicity.

 

Drug-Food Interactions

  • Alcohol: Strictly avoid alcohol, as it drastically increases the danger of liver damage and stomach bleeding when combined with this medicine.

 

Drug-Disease Interactions

  • Liver disease: Taking Nise 100 Tablet can worsen liver function and cause serious liver damage; do not take this if you have active or historical liver issues.
  • Stomach ulcers or bleeding: Can trigger severe internal bleeding or worsen existing ulcers.
    Kidney or heart failure: May cause fluid retention, worsening high blood pressure, heart failure, or kidney function.
     
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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FAQs

Nise 100 Tablet is used to relieve pain, including menstrual pain and dental pain.

Nise 100 Tablet works by blocking the effect of a chemical known as prostaglandin, which is responsible for inducing pain and inflammation in the body.

No, Nise 100 Tablet is not indicated for stomach pain. If you have stomach pain post-ingestion, it may be a sign of a stomach ulcer or gastric bleeding. Do not take Nise 100 Tablet in this condition. It is better to inform your doctor if you experience stomach pain after taking this medication.

No, Nise 100 Tablet should not be taken as a long-term medication as it may lead to stomach ulcers/bleeding and kidney problems. Take Nise 100 Tablet in the doses and for the duration as mentioned by your doctor.

Yes, Nise 100 Tablet should preferably be taken with food to avoid an upset stomach. If taken on an empty stomach, it may cause stomach irritation and upset stomach.

Nise 100 Tablet may cause dizziness. If you feel dizzy, please rest and avoid driving, as it can be harmful.

No, Nise 100 Tablet does not cause weight gain.

Nise 100 Tablet is not recommended for children below 12 years of age. If you have any concerns, consult a child's specialist before giving Nise 100 Tablet to your child.

Nise 100 Tablet may cause side effects such as nausea, vomiting, or diarrhoea. If these side effects persist or worsen, please consult your doctor.

Nise 100 Tablet is not an antibiotic. It belongs to the class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs; pain-relieving drugs), which help in relieving pain associated with several disease conditions.

You are not recommended to take Nise 100 Tablet with paracetamol as both the medicines belong to the same class known as non-steroidal anti-inflammatory drugs (NSAIDs), and taking them together may increase the risk of gastric ulceration and bleeding. However, please consult your doctor before using Nise 100 Tablet with other medicines.

Nise 100 Tablet does not contain aspirin. It contains Nimesulide.

Nise 100 Tablet is safe when used as prescribed by your doctor.

You can take Nise 100 Tablet for headache only when advised by your doctor.

Nise 100 Tablet does not make you drowsy at prescribed doses. However, taking too much of Nise 100 Tablet can make you drowsy (feeling sleepy).

No, Nise 100 Tablet does not contain sulphur.

Nise 100 Tablet can be taken with ibuprofen. However, please consult your doctor before taking Nise 100 Tablet with other medicines to avoid drug interactions.

Nise 100 Tablet can be taken with aspirin. However, please consult your doctor before taking Nise 100 Tablet with other medicines to avoid drug interactions.

No, in India, Nise 100 Tablet is not banned.

Nise 100 Tablet is usually not recommended during breastfeeding. Therefore, take your doctor’s advice before using Nise 100 Tablet if you are breastfeeding.

No, Nise 100 Tablet is not recommended during pregnancy, especially in the last three months. There have been reports of kidney failure in newborn babies if Nise 100 Tablet was used in the late stage of pregnancy. Consult your doctor before taking Nise 100 Tablet or any medicine during pregnancy.

Nise 100 Tablet is safe in asthma patients if taken as advised by your doctor. However, always inform your doctor about your disease history in case you have asthma and if you are taking other medicines.

No, you should not take Nise 100 Tablet on an empty stomach. Taking it with or after a meal helps protect your stomach lining and reduces the risk of side effects like indigestion, heartburn, or stomach pain. Talk to your doctor if you continue to experience stomach discomfort.

Nise 100 Tablet is absorbed quickly by the body, and meaningful pain relief typically begins within 30 to 60 minutes after taking it. If you do not feel better after a few days, talk to your doctor.

Nise 100 Tablet is only meant for short-term pain relief and should not be used as a long-term daily treatment for chronic arthritis. Using it for more than 15 days increases the risk of serious liver damage. Talk to your doctor to find a safer long-term treatment plan for your arthritis.

No, you must absolutely avoid alcohol while taking Nise 100 Tablet . Both alcohol and this medication are processed by the liver, and combining them significantly increases your risk of severe liver damage and stomach bleeding. Talk to your doctor if you have concerns about alcohol use.

No, Nise 100 Tablet is generally not recommended for use during pregnancy, especially in the last three months, as it can harm the unborn baby. It is also not recommended for breastfeeding mothers. Talk to your doctor for safer pain relief alternatives.

If you feel dizzy or sleepy after taking Nise 100 Tablet , avoid driving, riding a bicycle, or operating tools and machinery. Rest in a safe place until you feel fully alert. Talk to your doctor if this side effect persists or worsens.

No, you should not take Nise 100 Tablet with other pain relievers unless advised by your doctor. Taking it with paracetamol may increase the risk of liver damage. Taking it with other NSAIDs such as ibuprofen or aspirin may increase the risk of stomach ulcers, gastrointestinal bleeding, and liver-related side effects. Talk to your doctor or pharmacist before combining any pain medications.

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While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Dr. Reddy's Laboratories Ltd., 8-2-337, Road No. 3, Banjara Hills, Hyderabad, Telangana 500034, INDIA
Other Info - NIS0001

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