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Nisgin Tablet is used for the relief of painful skeletal muscle spasms. It contains Nimesulide and Chlorzoxazone, which provide relief from skeletal muscle spasms, pain or stiffness. It may cause common side effects such as nausea, vomiting, diarrhoea, weakness, and stomach upset. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Manufacturer/Marketer :

Kniss Laboratories Pvt Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Nisgin Tablet

Nisgin Tablet is an oral prescription medication used to relieve acute pain associated with muscle spasms. It helps treat conditions involving severe muscle stiffness, tension, and discomfort arising from sprains, strains, or other muscle injuries.

To get the best results, you must take Nisgin Tablet consistently and exactly as prescribed by your doctor, typically for a short duration. It is highly recommended to take this medication with food or after a meal to help prevent stomach irritation. Alongside taking your medicine, resting the affected muscle, staying well-hydrated, and performing gentle stretches can support your recovery.

While taking Nisgin Tablet, some people may experience mild side effects like drowsiness, dizziness, or a mild upset stomach. However, you must talk to your doctor immediately if you notice serious signs such as yellowing of your skin or eyes, dark urine, or severe abdominal pain, as these could point to liver damage.

Talk to your doctor before starting this medication if you have a history of stomach ulcers, kidney problems, or heart conditions. Do not take this if you have active liver disease, severe kidney impairment, or a history of allergic reactions to other pain relievers.

Nisgin Tablet can interact with other drugs like blood thinners or other pain relievers, making it important to share your full medication list with your healthcare provider. Avoid drinking alcohol while on this medication, as it significantly increases the risk of drowsiness and liver damage. Pregnant, breastfeeding, or elderly individuals should consult their doctor before using Nisgin Tablet to ensure safety. Nisgin Tablet is approved only for short-term use in adults and is not recommended for children below 12 years of age. Due to the risk of serious liver-related side effects, treatment duration should not exceed the period prescribed by your doctor. 

Uses of Nisgin Tablet

Nisgin Tablet is used in the treatment of Musculoskeletal pain. The detailed uses of Nisgin Tablet are as follows:

  • Muscle spasms: Nisgin Tablet helps by relaxing stiff muscles and easing the severe pain associated with sudden, involuntary muscle contractions.
  • Back pain: It targets both the muscle tension and the underlying inflammation in the back, making movement easier.
  • Sprains and strains: It relieves acute musculoskeletal pain and swelling caused by sudden physical injuries.

Key Benefits

Nisgin Tablet helps relieve musculoskeletal pain, inflammation, and muscle stiffness, allowing for more comfortable movement and daily activities. By addressing both pain and muscle tightness, it supports faster recovery and improved physical function. Benefits may include:

  • Helps relieve muscle pain and discomfort.
  • Reduces inflammation and swelling associated with musculoskeletal conditions.
  • Helps relax tight muscles and reduce muscle stiffness.
  • Improves mobility and flexibility during recovery.
  • Supports participation in daily activities and physical therapy with greater comfort.
  • Promotes faster recovery and overall physical well-being.

Directions for Use

  • Take Nisgin Tablet with food to prevent stomach upset.
  • Follow your doctor’s recommendations on the dosage and timing of this medication to achieve optimal results.
  • Swallow Nisgin Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Nisgin Tablet Works

Nisgin Tablet contains Nimesulide and Chlorzoxazone. • Nimesulide: It helps relieve pain, swelling, and inflammation by reducing the substances in the body that cause these symptoms. This helps improve comfort and mobility. • Chlorzoxazone: It helps relax stiff and tense muscles, reducing muscle spasms and discomfort. This helps improve movement and provides relief from muscle-related pain.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Nisgin Tablet as it may increase the risk of stomach bleeding.

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Pregnancy

Consult your doctor

Please consult your doctor if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Please consult your doctor if you are breastfeeding; your doctor will decide whether Nisgin Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

Nisgin Tablet may cause dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Nisgin Tablet is not recommended in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Nisgin Tablet should not be given to children as the safety and effectiveness were not established.

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Heart

Unsafe

This medicine is contraindicated in cardiac patients due to its adverse effects.

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Geriatrics

Caution

Nisgin Tablet can be given in elderly patients with caution and only if prescribed by the doctor.

What if I have taken an overdose of Nisgin Tablet

In case of an accidental overdose, seek immediate emergency medical attention or contact a poison control center right away. Symptoms of an overdose may include severe drowsiness, nausea, vomiting, stomach pain, or difficulty breathing.

Diet & Lifestyle Advise

  • Stay hydrated: Drink plenty of water throughout the day, as dehydration can worsen muscle spasms and cramps.
  • Use heat or cold therapy: Apply an ice pack to the affected area for the first 48 hours to reduce swelling, then switch to a warm compress or heating pad to relax tight muscles.
  • Gentle movement: Avoid prolonged bed rest. Gentle stretching and light walking can prevent muscle stiffness and promote blood flow to speed up healing.
  • Supportive posture: Use ergonomic chairs and maintain good posture while sitting or standing to avoid putting unnecessary strain on recovering muscles.
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How Soon It Starts Working

The time required for Nisgin Tablet to start to work: The time required for Nisgin Tablet to start to work is 30 minutes after administration. 

The time for which the effects of Nisgin Tablet last: The effect of Nisgin Tablet lasts for 6 to 8 hours.

What if you forget to take Nisgin Tablet

If you miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Monitor for signs of liver problems: Nisgin Tablet may affect the liver. Use it only for the prescribed duration and contact your doctor if you develop symptoms such as loss of appetite, nausea, unusual tiredness, dark urine, or yellowing of the skin or eyes.
  • Use caution during activities requiring alertness: Nisgin Tablet may cause significant drowsiness, dizziness, or reduced concentration. Avoid driving, operating heavy machinery, or performing hazardous tasks until you know how the medicine affects you.
  • Avoid taking other pain medicines without medical advice: Do not use other NSAIDs or paracetamol-containing products while taking Nisgin Tablet unless advised by your doctor, as this may increase the risk of stomach irritation and liver-related side effects.
     
  • Inspect the medicine before use: Check that the blister pack is sealed and undamaged. Do not use the tablets if the packaging is torn or if the tablets appear discolored or altered.
  • Use only as directed: Nisgin Tablet is not recommended for children below 12 years of age and should not be used for longer than prescribed, as prolonged use may increase the risk of serious liver problems.
  • Seek immediate medical attention for serious symptoms: Get emergency medical help if you develop yellowing of the skin or eyes, dark urine, severe abdominal pain, facial swelling, difficulty breathing, widespread rash, vomiting blood, black tarry stools, severe dizziness, loss of consciousness, breathing difficulties, or if an overdose is suspected.

Drug-Drug Interactions

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Drug-Drug Interactions

  • Blood thinners (e.g.,  warfarin): Taking these together may increase the risk of stomach bleeding.
  • Other pain relievers (NSAIDs): Combining Nisgin Tablet with other NSAIDs can increase the risk of severe stomach ulcers and bleeding.
  • Certain blood pressure medications (like ACE inhibitors): Nisgin Tablet may reduce the effectiveness of these medications and increase the risk of kidney issues.

Drug-Food Interactions

Alcohol: Avoid consuming alcohol, as it can cause extreme drowsiness and significantly increases the risk of serious liver damage when combined with this medication.

Drug-Disease Interactions

  • Liver disease: Do not take this medication if you have a history of liver impairment, as it can worsen liver damage.
  • Stomach ulcers: If you have active or recurrent stomach ulcers or gastrointestinal bleeding, Nisgin Tablet can worsen your condition.
  • Kidney impairment: This medication should be used with extreme caution or avoided in people with severe kidney disease, as it can affect kidney function.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[MUSCLE RELAXANTS]

FAQs

Nisgin Tablet is used for the relief of painful skeletal muscle spasms.
Nisgin Tablet contains Nimesulide and Chlorzoxazone. Nimesulide works by inhibiting the synthesis of prostaglandins responsible for pain and inflammation. Chlorzoxazone acts on the brain and spinal cord centres, where it inhibits the multisynaptic reflex involved in muscle spasms, thereby providing relief from skeletal muscle spasms. Together, Nisgin Tablet helps in relieving musculoskeletal pain.
Nisgin Tablet is generally prescribed for short-term use. Avoid taking Nisgin Tablet for longer durations unless prescribed by the doctor, as it could lead to unpleasant side effects and liver damage. Use the minimum effective dose for the shortest duration of time.
Do not take Nisgin Tablet along with other painkiller medicines unless prescribed by the doctor, as it can lead to unpleasant side effects and can increase the risk of stomach bleeding associated with NSAIDs.
Physical therapy helps relieve muscle spasms. Therefore, proper rest and physical therapy are recommended to enhance and complement treatment with Nisgin Tablet.
Diarrhoea might be a side-effect of Nisgin Tablet. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you experience severe diarrhoea or if you find blood in stools.
Nisgin Tablet contains Nimesulide, an NSAID, which can enhance the activity of anticoagulant drugs leading to an increased risk of bleeding complications. Therefore, it is not recommended to take anti-coagulants along with Nisgin Tablet unless told by the doctor.
No, you should avoid alcohol while taking Nisgin Tablet. Alcohol can increase the risk of severe drowsiness and significantly raises the chance of liver damage. Talk to your doctor if you have concerns.
It is best not to take Nisgin Tablet on an empty stomach. Taking it with food or milk helps protect your stomach lining and reduces the risk of stomach upset.
If you notice dark urine, yellowing of your skin or eyes, or severe upper stomach pain, stop taking Nisgin Tablet immediately and contact your doctor. These can be signs of liver irritation or damage.
Pregnant or breastfeeding women should avoid taking Nisgin Tablet unless specifically advised by their doctor. Some ingredients in this medication may not be safe for the developing baby. Talk to your doctor to discuss safer alternatives.
Many people may begin to notice relief from muscle pain and stiffness within a few hours of taking Nisgin Tablet. However, the exact onset of relief can vary depending on the dose, formulation, severity of symptoms, and individual response to treatment.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

1445 Ross Ave, Suite 1400, Dallas, Texas 75202
Other Info - NI96283
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