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compositionComposition:GLYCERYL TRINITRATE-5MG
prescription
Prescription Medicine
info
Nitrocin 25 mg Injection 5 ml
Nitrocin 25 mg Injection 5 ml
Nitrocin 25 mg Injection 5 ml
Nitrocin 25 mg Injection 5 ml
Nitrocin 25 mg Injection 5 ml

Nitrocin 25 mg Injection 5 ml belongs to the class of anti-anginal drugs, which is used in the treatment of angina pectoris, heart attack (myocardial infarction) and Perioperative hypertension. It helps relax and widen blood vessels, improving blood flow and reducing the workload on the heart.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

GLYCERYL TRINITRATE-5MG

Manufacturer/Marketer :

Samarth Life Sciences Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Nitrocin 25 mg Injection 5 ml

Nitrocin 25 mg Injection 5 ml is primarily used for treating angina pectoris and myocardial infarction. Nitrocin 25 mg Injection 5 ml can also be used to control intraoperative blood pressure. Angina occurs when the heart does not receive sufficient oxygen.

Nitrocin 25 mg Injection 5 ml contains Glyceryl Trinitrate, which relaxes blood vessels (veins and arteries).

Nitrocin 25 mg Injection 5 ml may cause side effects like headache, hypotension, tachycardia (fast heart rate), dyspnea (shortness of breath), dizziness, light-headedness, and blurred vision. Most of these side effects do not require medical attention. However, if the side effects are persistent, reach out to your doctor.

Inform your doctor if you are allergic or hypersensitive to any component present in Nitrocin 25 mg Injection 5 ml. If you are pregnant, suspect you are pregnant, plan to have a baby, or if you are breastfeeding, inform your doctor before receiving this medicine. 

Uses of Nitrocin 25 mg Injection 5 ml

Nitrocin 25 mg Injection 5 ml is used in the treatment of heart-related conditions such as:

  • Angina pectoris: It helps relieve chest pain by relaxing and widening the blood vessels, improving blood flow to the heart.
  • Myocardial infarction (heart attack): Nitrocin 25 mg Injection 5 ml aids in reducing the heart's workload and oxygen demand during a heart attack.

Key Benefits

  • Helps quickly reduce chest pain caused by reduced blood flow to the heart.
  • Relaxes and widens blood vessels, allowing better blood flow.
  • Decreases the pressure on the heart, helping it pump blood more easily.
  • Helps improve heart failure symptoms by reducing strain on the heart.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Nitrocin 25 mg Injection 5 ml will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Nitrocin 25 mg Injection 5 ml Works

Nitrocin 25 mg Injection 5 ml contains Glyceryl Trinitrate, a natural vasodilator that works by relaxing the blood vessels (veins and arteries). This boosts the blood supply to your heart, allowing more oxygen to reach your heart muscles and reducing chest pain. Thus, it prevents and treats various heart conditions.
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Alcohol

Unsafe

Concomitant use of nitrates and alcohol may cause hypotension. So intake of Nitrocin 25 mg Injection 5 ml should be avoided with Nitrocin 25 mg Injection 5 ml.

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Pregnancy

Consult your doctor

Nitrocin 25 mg Injection 5 ml should not be used during pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Nitrocin 25 mg Injection 5 ml.

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Breast Feeding

Consult your doctor

The safety of Nitrocin 25 mg Injection 5 ml is unknown during breastfeeding. So, inform your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Nitrocin 25 mg Injection 5 ml.

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Driving

Unsafe

Nitrocin 25 mg Injection 5 ml can cause dizziness. So, operating machinery and driving, both of which require concentration, should be avoided.

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Liver

Consult your doctor

Tell your doctor before receiving the Nitrocin 25 mg Injection 5 ml if you have a history of liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Consult your doctor

Tell your doctor before receiving the Nitrocin 25 mg Injection 5 ml if you have had a kidney impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Unsafe

Safety of Nitrocin 25 mg Injection 5 ml is not known in children below the age of 18 years.

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Heart

Caution

Nitrocin 25 mg Injection 5 ml is used to treat heart conditions like angina by improving blood flow. It must be administered with caution, especially in cases of low blood pressure or recent heart events.

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Geriatrics

Caution

Geriatric patients can receive Nitrocin 25 mg Injection 5 ml, but they may be more sensitive to its effects, such as dizziness or low blood pressure. Careful monitoring and dose adjustments help ensure safe and effective use.

What if I have taken an overdose of Nitrocin 25 mg Injection 5 ml

Nitrocin 25 mg Injection 5 ml is administered by a health care professional in a hospital setting. Hence, the chances of overdose are less. Overdose toxicity primarily results from an augmented vasodilatory response. Expected in these patients are hypotension, venous pooling, increased vasodilation, and decreased cardiac output. Your doctor may take necessary measures if an overdose is suspected.

Diet & Lifestyle Advise

Diet

  • Eat a heart-healthy diet with plenty of fruits, vegetables, and whole grains.
  • Reduce salt intake to help control blood pressure and protect heart health.
  • Limit fatty and fried foods to maintain healthy cholesterol levels.

Lifestyle changes

  • Do moderate exercises such as walking or light stretching to maintain heart health.
  • Avoid heavy physical exertion that may trigger chest pain or angina.
  • Rest immediately if chest pain occurs and use the sublingual tablet as prescribed.
  • Consult your doctor before starting new exercises, especially if you have heart disease.

Stress management

  • Practice relaxation techniques such as deep breathing or meditation to reduce stress.
  • Maintain regular sleep habits to support heart health and reduce anxiety.
  • Avoid emotional stress and overexertion, as they may trigger angina (chest pain).

Habits

  • Avoid excessive alcohol and smoking, as it may increase dizziness and lower blood pressure.

Have a query?

How Soon It Starts Working

  • The time required for Nitrocin 25 mg Injection 5 ml to start to work: Nitrocin 25 mg Injection 5 ml ideally shows its action within 1 to 2 minutes after administration.
  • The time for which the effects of Nitrocin 25 mg Injection 5 ml last: The effect of Nitrocin 25 mg Injection 5 ml lasts for 3 to 4 minutes.

What if you forget to take Nitrocin 25 mg Injection 5 ml

As this medicine is administered in a hospital by your healthcare professional, the chances of missing a dose are less. However, if you have any concerns, contact your doctor.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Inform your doctor if you are allergic to Glyceryl Trinitrate, any of the other ingredients of this medicine, or any other nitrates.
  • It is not recommended to take Nitrocin 25 mg Injection 5 ml if you have a shock (a medical condition where insufficient blood flow reaches the body tissues) or low blood pressure or low blood volume or low blood oxygen or have fluid accumulation in the lung, or have ever had a serious head injury, cerebral haemorrhage (bleeding in the brain) or have or had heart conditions.
  • It is strictly recommended not to take Nitrocin 25 mg Injection 5 ml if you use riociguat, a medicine used to treat pulmonary hypertension.
  • Please check with the doctor before taking the Nitrocin 25 mg Injection 5 ml if you have/had severe liver or kidney problems, an underactive thyroid (thyroid dysfunction), or hypothermia (body temperature is lower than normal).

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interaction: Nitrocin 25 mg Injection 5 ml may interact with certain medicines and increase side effects:

  • Erectile dysfunction medication (sildenafil, tadalafil)
    • Potential effect: May cause a rapid decrease in blood pressure
  • Antidepressants (amitriptyline)
    • Potential effect: May increase the risk of low BP and lightheadedness.
  • Medicines used for High BP (atenolol, amlodipine)
    • Potential effect: May enhance the BP-lowering effect.
  • Blood thinners (warfarin)
    • Potential effect: May increase the risk of bleeding.

Drug-Food Interaction: Limit alcohol consumption and caffeine-containing drinks.

Drug-Disease Interaction: Inform your doctor if you have a history of the following conditions before taking Nitrocin 25 mg Injection 5 ml, as it may worsen your condition or cause complications.

  • Myocardial infarction
  • Congestive heart failure
  • Anaemia
  • Hemodialysis (a procedure where a dialysis machine and a special filter called an artificial kidney)
  • Hypotension
  • Intracranial pressure
  • Pericarditis (inflammation of the pericardium)
  • Hypertrophic cardiomyopathy
  • Glaucoma.
Glyceryl trinitrateAvanafil
Critical
Glyceryl trinitrateVardenafil
Critical

Drug-Drug Interactions

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Glyceryl trinitrateAvanafil
Critical
How does the drug interact with Nitrocin 25mg/5ml Inj:
Taking Avanafil and Nitrocin 25mg/5ml Inj together can increase the risk or severity of low blood pressure.

How to manage the interaction:
Combining Avanafil and Nitrocin 25mg/5ml Inj is generally avoided as it can lead to an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, and priapism (prolonged and painful erection unrelated to sexual activity), consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Glyceryl trinitrateVardenafil
Critical
How does the drug interact with Nitrocin 25mg/5ml Inj:
Taking Vardenafil and Nitrocin 25mg/5ml Inj together can increase the risk or severity of low blood pressure.

How to manage the interaction:
Combining Vardenafil and Nitrocin 25mg/5ml Inj is generally avoided as it can lead to an interaction, but it can be taken if your doctor has advised it. However, if you experience symptoms like dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, and priapism (prolonged and painful erection unrelated to sexual activity), consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Glyceryl trinitrateMethylergometrine
Critical
How does the drug interact with Nitrocin 25mg/5ml Inj:
Coadministration of Methylergometrine with Nitrocin 25mg/5ml Inj can increase the levels and side effects of Methylergometrine.

How to manage the interaction:
Taking Methylergometrine with Nitrocin 25mg/5ml Inj is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, headache, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor. Do not discontinue any medications without first consulting your doctor.
Glyceryl trinitrateTetracaine
Severe
How does the drug interact with Nitrocin 25mg/5ml Inj:
Coadministration of Tetracaine and Nitrocin 25mg/5ml Inj has the potential to induce methemoglobinemia (a rare condition where red blood cells are unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking Tetracaine and Nitrocin 25mg/5ml Inj together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as grey discolouration of the skin, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Glyceryl trinitratePrilocaine
Severe
How does the drug interact with Nitrocin 25mg/5ml Inj:
Coadministration of Prilocaine and Nitrocin 25mg/5ml Inj has the potential to induce methemoglobinemia (a rare condition where red blood cells are unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking prilocaine and Nitrocin 25mg/5ml Inj together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Glyceryl trinitrateProcaine
Severe
How does the drug interact with Nitrocin 25mg/5ml Inj:
Coadministration of Procaine and Nitrocin 25mg/5ml Inj has the potential to induce methemoglobinemia (a rare condition where red blood cells are unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking procaine and Nitrocin 25mg/5ml Inj together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Glyceryl trinitrateSodium nitrite
Severe
How does the drug interact with Nitrocin 25mg/5ml Inj:
Coadministration of Sodium nitrite and Nitrocin 25mg/5ml Inj has the potential to induce methemoglobinemia (a rare condition where red blood cells are unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking Sodium nitrite and Nitrocin 25mg/5ml Inj together can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as grey discolouration of the skin, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not discontinue any medications without first consulting your doctor.
Glyceryl trinitrateMepivacaine
Severe
How does the drug interact with Nitrocin 25mg/5ml Inj:
Coadministration of Mepivacaine and Nitrocin 25mg/5ml Inj has the potential to induce methemoglobinemia (a rare condition where red blood cells are unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking Mepivacaine and Nitrocin 25mg/5ml Inj together can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as grey discolouration of the skin, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not discontinue any medications without consulting your doctor.
Glyceryl trinitrateRopivacaine
Severe
How does the drug interact with Nitrocin 25mg/5ml Inj:
Coadministration of Ropivacaine and Nitrocin 25mg/5ml Inj has the potential to induce methemoglobinemia (a rare condition where red blood cells are unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking Ropivacaine and Nitrocin 25mg/5ml Inj together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Glyceryl trinitrateChloroprocaine
Severe
How does the drug interact with Nitrocin 25mg/5ml Inj:
Coadministration of Chloroprocaine and Nitrocin 25mg/5ml Inj can increase the risk of developing methemoglobinemia (a rare condition where red blood cells are unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking Chloroprocaine and Nitrocin 25mg/5ml Inj together can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as grey discoloration of the skin, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIANGINALS]

FAQs

Nitrocin 25 mg Injection 5 ml belongs to the class of anti-anginal medication, primarily used for treating angina pectoris and myocardial infarction. Nitrocin 25 mg Injection 5 ml can also use to control intraoperative blood pressure.
Nitrocin 25 mg Injection 5 ml contains Glyceryl Trinitrate, a natural vasodilator that relaxes the muscles surrounding blood vessels, making the heart's job easier.
Nitrocin 25 mg Injection 5 ml may result in hypotension (low blood pressure). Therefore, regular blood pressure monitoring is recommended while on Nitrocin 25 mg Injection 5 ml therapy.
Nitrocin 25 mg Injection 5 ml is prescribed when a quick response is needed, or when individuals cannot take tablets.
No, you should not take Nitrocin 25 mg Injection 5 ml with the erectile dysfunction medication, such as sildenafil, vardenafil, or tadalafil, as the simultaneous administration of Nitrocin 25 mg Injection 5 ml and these drugs can dangerously drop the blood pressure.
Yes, Nitrocin 25 mg Injection 5 ml can cause a headache. Please increase fluid intake as it is known to cause headaches when taking Nitrocin 25 mg Injection 5 ml. If the problem persists, consult your doctor and do as advised.
Caution should be exercised while using Nitrocin 25 mg Injection 5 ml, especially if you have hyperthyroidism (overactive thyroid); inform your doctor before taking Nitrocin 25 mg Injection 5 ml because it may mask your symptoms or make it difficult to recognise the signs of excess thyroid hormone in the body.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.6296 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  2. Glyceryl Trinitrate 5 mg/ml Sterile Concentrate — Summary of Product Characteristics (SmPC) – (emc) [Internet]. Medicines.org.uk. 2025 [Accessed on 26 Sep 2025] Check here
  3. Kim KH, Kerndt CC, Adnan G, et al. Nitroglycerin. [Updated 2023 Jul 31]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; [Accessed on 11 Mar 2025] Check here
  4. Elkayam U, Aronow WS. Glyceryl trinitrate (nitroglycerin) ointment and isosorbide dinitrate: a review of their pharmacological properties and therapeutic use. Drugs. 1982 Mar;23(3):165-94 [Accessed on 11 Mar 2025] Check here
  5. CDSCO. [Accessed on 02 Jun. 2026] Check here
  6. Torrent Pharmaceuticals Ltd. VASOVIN XL: Summary of Product Characteristics [Internet]. Feb 2022 [Accessed on 2025 Sep 26]Check here

Country of origin

India

Manufacturer/Marketer address

Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.
Other Info - NIT0022

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