Nitrovir 25 mg Injection 5 ml
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About Nitrovir 25 mg Injection 5 ml
Nitrovir 25 mg Injection 5 ml belongs to the class of anti-anginal medication, primarily used for treating angina pectoris and myocardial infarction. Besides this, it is also used to control intraoperative blood pressure.
Nitrovir 25 mg Injection 5 ml contains nitroglycerin, a natural vasodilator that works by relaxing the blood vessels. This boosts the blood supply to your heart, allowing more oxygen to reach your heart muscles and reducing chest pain.
Sometimes, you may experience headaches, low blood pressure, fast heart rate, dizziness, light-headedness, and blurred vision as side effects. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.
Inform your doctor if you are allergic to any component present in Nitrovir 25 mg Injection 5 ml. If you are pregnant or breastfeeding, consult your doctor before receiving this medicine. Keep your doctor informed about your medical history and ongoing medications to rule out any potential interactions.
Uses of Nitrovir 25 mg Injection 5 ml
Nitrovir 25 mg Injection 5 ml is used to treat angina, peri-operative high blood pressure, and myocardial infarction. The detailed uses of Nitrovir 25 mg Injection 5 ml are as follows:
- Management of peri-operative hypertension: Nitrovir 25 mg Injection 5 ml is used to treat high blood pressure during or after surgery.
- Treatment of congestive heart failure: Nitrovir 25 mg Injection 5 ml helps treat congestive heart failure associated with acute myocardial infarction (heart attack).
- Relieves angina: It relieves angina pectoris in patients not responding to sublingual nitroglycerin or beta-blockers.
- During surgery: It is used to induce controlled low blood pressure (hypotension) during surgery (intraoperative hypotension).
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Directions for Use
- Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
- Nitrovir 25 mg Injection 5 ml will be administered by the doctor or healthcare professional.
- Do not self-administer.
Key Benefits
- Nitrovir 25 mg Injection 5 ml contains Nitroglycerin, a fast-acting vasodilator that relaxes and widens blood vessels, leading to improved blood flow and reduced heart workload.
- It helps control high blood pressure during surgery (perioperative hypertension) during cardiovascular procedures like intubation, anaesthesia, sternotomy, and cardiac bypass, as well as in the immediate post-surgical period.
- It manages congestive heart failure after a heart attack by reducing the strain on the heart and improving circulation.
- Nitrovir 25 mg Injection 5 ml relieves angina (chest pain) in patients who do not respond to other antianginal medications, by improving blood and oxygen supply to the heart muscle.
- It is also used to induce controlled low blood pressure during surgery to create a stable, low-pressure environment for certain surgical procedures, reducing bleeding and improving surgical conditions.
How Nitrovir 25 mg Injection 5 ml Works
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What if I have taken an overdose of Nitrovir 25 mg Injection 5 ml
Drug Warnings
- Do not take Nitrovir 25 mg Injection 5 ml if you are allergic to nitroglycerin or any of the other ingredients of this medicine.
- Inform your doctor if you have/had a shock (a medical condition where insufficient blood flow reaches the body tissues), low blood pressure, low blood volume, low blood oxygen, fluid accumulation in the lungs, serious head injury, cerebral haemorrhage (bleeding in the brain) or heart conditions.
- It is recommended not to take Nitrovir 25 mg Injection 5 ml if you use riociguat, a medicine used to treat pulmonary hypertension.
- Please check with the doctor before taking Nitrovir 25 mg Injection 5 ml if you have/had severe liver or kidney problems, an underactive thyroid (thyroid dysfunction), or hypothermia (body temperature is lower than normal).
- Consult your doctor if you are pregnant, planning pregnancy or breastfeeding.
- Let your doctor know if you are taking any other medicines, including supplements or herbal products.
Drug-Drug Interactions
Drug-Drug Interactions
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Coadministration of Methylergometrine with Nitrovir 25 mg Injection 5 ml can increase the levels and side effects of Methylergometrine.
How to manage the interaction:
Taking Methylergometrine with Nitrovir 25 mg Injection 5 ml is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, headache, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor. Do not discontinue any medications without first consulting your doctor.
Taking Vardenafil and Nitrovir 25 mg Injection 5 ml together can increase the risk or severity of low blood pressure.
How to manage the interaction:
Combining Vardenafil and Nitrovir 25 mg Injection 5 ml is generally avoided as it can lead to an interaction, but it can be taken if your doctor has advised it. However, if you experience symptoms like dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, and priapism (prolonged and painful erection unrelated to sexual activity), consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Taking Avanafil and Nitrovir 25 mg Injection 5 ml together can increase the risk or severity of low blood pressure.
How to manage the interaction:
Combining Avanafil and Nitrovir 25 mg Injection 5 ml is generally avoided as it can lead to an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, and priapism (prolonged and painful erection unrelated to sexual activity), consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Coadministration of Sodium nitrite and Nitrovir 25 mg Injection 5 ml has the potential to induce methemoglobinemia (a rare condition where red blood cells are unable to carry oxygen effectively to the tissues).
How to manage the interaction:
Although taking Sodium nitrite and Nitrovir 25 mg Injection 5 ml together can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as grey discolouration of the skin, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not discontinue any medications without first consulting your doctor.
Coadministration of bupivacaine and Nitrovir 25 mg Injection 5 ml can increase the risk and severity of developing methemoglobinemia, (Red blood cells are unable to carry oxygen effectively to the tissues).
How to manage the interaction:
Although taking bupivacaine and Nitrovir 25 mg Injection 5 ml together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
Coadministration of Chloroprocaine and Nitrovir 25 mg Injection 5 ml can increase the risk of developing methemoglobinemia (a rare condition where red blood cells are unable to carry oxygen effectively to the tissues).
How to manage the interaction:
Although taking Chloroprocaine and Nitrovir 25 mg Injection 5 ml together can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as grey discoloration of the skin, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not discontinue any medications without consulting your doctor.
Coadministration of Tetracaine and Nitrovir 25 mg Injection 5 ml has the potential to induce methemoglobinemia (a rare condition where red blood cells are unable to carry oxygen effectively to the tissues).
How to manage the interaction:
Although taking Tetracaine and Nitrovir 25 mg Injection 5 ml together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as grey discolouration of the skin, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Coadministration of Ropivacaine and Nitrovir 25 mg Injection 5 ml has the potential to induce methemoglobinemia (a rare condition where red blood cells are unable to carry oxygen effectively to the tissues).
How to manage the interaction:
Although taking Ropivacaine and Nitrovir 25 mg Injection 5 ml together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Coadministration of Etidocaine and Nitrovir 25 mg Injection 5 ml can increase the risk of developing methemoglobinemia (a rare condition where red blood cells are unable to carry oxygen effectively to the tissues).
How to manage the interaction:
Although taking Etidocaine and Nitrovir 25 mg Injection 5 ml together can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as grey discoloration of the skin, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not discontinue any medications without consulting your doctor.
Coadministration of Levobupivacaine and Nitrovir 25 mg Injection 5 ml can increase the risk of developing methemoglobinemia (a rare condition where red blood cells are unable to carry oxygen effectively to the tissues).
How to manage the interaction:
Although taking Levobupivacaine and Nitrovir 25 mg Injection 5 ml together can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as grey discolouration of the skin, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not discontinue any medications without consulting your doctor.
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Diet & Lifestyle Advise
- Follow a cholesterol-lowering diet.
- Consume a low-salt and low-fat diet.
- Exercise regularly. It helps in maintaining proper weight and lowers cholesterol.
- Limit salt and sugar intake.
- Avoid smoking and alcohol consumption.
- Choose healthy fats and cut down on trans fat.
- Include omega-3 fatty acids, fiber-rich food, fruits, and vegetables.
- Get active by doing physical activities such as swimming, brisk walking, or jogging. Take the stairs instead of elevators/lifts.
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Alcohol
Safe if prescribed
Concomitant use of nitrates and alcohol may cause hypotension. So intake of Nitrovir 25 mg Injection 5 ml should be avoided with Nitrovir 25 mg Injection 5 ml.
Pregnancy
Consult your doctor
Nitrovir 25 mg Injection 5 ml should not be used during pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Nitrovir 25 mg Injection 5 ml.
Breast Feeding
Consult your doctor
The safety of Nitrovir 25 mg Injection 5 ml is not known in breastfeeding women. So, inform your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Nitrovir 25 mg Injection 5 ml.
Driving
Safe if prescribed
Nitrovir 25 mg Injection 5 ml can cause dizziness. So, operating machinery and driving, which require concentration, should be avoided.
Liver
Consult your doctor
Tell your doctor before receiving Nitrovir 25 mg Injection 5 ml if you have a history of liver impairment/disorder. Your doctor will prescribe only if the benefits outweigh the risks.
Kidney
Consult your doctor
Tell your doctor before receiving Nitrovir 25 mg Injection 5 ml if you have a history of kidney impairment/disorder. Your doctor will prescribe only if the benefits outweigh the risks.
Children
Safe if prescribed
The safety of Nitrovir 25 mg Injection 5 ml is not known in children below the age of 18 years.
Heart
Nitrovir 25 mg Injection 5 ml is commonly used to treat heart conditions like angina and heart failure by relaxing blood vessels and improving blood flow. It should be administered under medical supervision, especially if you have low blood pressure or recent cardiac events.
Geriatrics
Consult your doctor
Geriatric patients can receive Nitrovir 25 mg Injection 5 ml, but it may be more sensitive to its effects like dizziness, low blood pressure, or fainting. Close monitoring and careful dose adjustments are essential to ensure safe use.
FAQs
Nitrovir 25 mg Injection 5 ml belongs to the class of anti-anginal medication, primarily used for treating angina pectoris and myocardial infarction. Nitrovir 25 mg Injection 5 ml can also be used to control intraoperative blood pressure.
Nitrovir 25 mg Injection 5 ml contains Nitroglycerin, a natural vasodilator that relaxes the muscles surrounding blood vessels, making the heart's job easier.
Nitrovir 25 mg Injection 5 ml may result in hypotension (low blood pressure). Therefore, regular blood pressure monitoring is recommended while on Nitrovir 25 mg Injection 5 ml therapy.
Nitrovir 25 mg Injection 5 ml is prescribed when a quick response is needed or individuals cannot take tablets.
No, you should not take Nitrovir 25 mg Injection 5 ml with the erectile dysfunction medication, such as sildenafil, vardenafil, or tadalafil, as the simultaneous administration of Nitrovir 25 mg Injection 5 ml and these drugs can drop the blood pressure dangerously.
Yes, Nitrovir 25 mg Injection 5 ml can cause a headache. Please increase fluid intake to cope with the headache. If the problem persists, consult your doctor and do as advised.
Caution should be exercised while using Nitrovir 25 mg Injection 5 ml, especially if you have hyperthyroidism (overactive thyroid); inform your doctor before taking Nitrovir 25 mg Injection 5 ml because it may mask your symptoms or make it difficult to recognise the signs of excess thyroid hormone in the body.
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Reference
- https://cdscoonline.gov.in/CDSCO/Drugs
- https://www.medicines.org.uk/emc/files/pil.6296.pdf
- https://www.mayoclinic.org/drugs-supplements/nitroglycerin-intravenous-route/description/drg-20072938#:~:text=Nitroglycerin%20injection%20is%20used%20to,low%20blood%20pressure)%20during%20surgery.
- https://reference.medscape.com/drug/glyceryl-trinitrate-iv-iv-nitroglycerin-nitroglycerin-iv-342278
