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compositionComposition:INSULIN GLARGINE-100IU
prescription
Prescription Medicine
info
Nobeglar-Uno 100IU Prefilled Pen 3 ml
Nobeglar-Uno 100IU Prefilled Pen 3 ml

Nobeglar-Uno 100IU Prefilled Pen 3 ml is used to treat type 1 and type 2 diabetes mellitus. It contains Insulin glargine, a long-acting insulin that works by replacing the insulin that is normally produced by the body. Sometimes, you may experience side effects such as injection site reactions. The injection site should be rotated to prevent skin changes such as lumps under the skin. Let the doctor know if you are taking any other medicines or have pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

INSULIN GLARGINE-100IU

Manufacturer/Marketer :

Mankind Pharma Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Nobeglar-Uno 100IU Prefilled Pen 3 ml

Nobeglar-Uno 100IU Prefilled Pen 3 ml is a long-acting insulin injection used to control high blood sugar in adults and children with diabetes mellitus. It is prescribed for both type 1 diabetes, where the body does not make insulin, and type 2 diabetes, where the body cannot use insulin properly. Maintaining stable insulin levels helps prevent serious long-term complications associated with high blood sugar.

You will typically inject Nobeglar-Uno 100IU Prefilled Pen 3 ml once a day. It is highly important to use it at the same time every day to maintain steady blood sugar levels in your body. Because this medication is an injection that works continuously over 24 hours, you can take it with or without food. Combining this injection with healthy food choices and regular physical activity is essential to get the best results from your treatment.

The most common side effect of this medication is low blood sugar (hypoglycemia), which can cause shakiness, sweating, and dizziness. Other common issues include mild reactions at the injection site, such as redness or swelling. If you experience any serious side effects, such as severe breathing difficulties, sudden swelling of your face or throat, or extreme dizziness, seek emergency medical help immediately.

Do not take this if you are currently experiencing an episode of low blood sugar or if you have ever had an allergic reaction to this medication or any of its ingredients. Before starting your treatment, talk to your doctor if you have kidney disease, liver damage, or heart failure, as these conditions may require special monitoring or dose adjustments.

Using alcohol while taking Nobeglar-Uno 100IU Prefilled Pen 3 ml can unpredictably affect your blood sugar levels, significantly increasing your risk of severe low blood sugar. Tell your doctor about all other medicines you are taking, as many drugs can interact with your insulin therapy. If you are pregnant, planning to become pregnant, breastfeeding, or are an older adult, talk to your doctor or pharmacist to ensure this medication is safe for your specific situation.

Uses of Nobeglar-Uno 100IU Prefilled Pen 3 ml

Your doctor may prescribe Nobeglar-Uno 100IU Prefilled Pen 3 ml to treat several conditions, including:

  • Type 1 Diabetes Mellitus: Nobeglar-Uno 100IU Prefilled Pen 3 ml helps replace the insulin your body is unable to produce naturally, keeping your daily blood sugar levels stable over a 24-hour period.
  • Type 2 Diabetes Mellitus: Nobeglar-Uno 100IU Prefilled Pen 3 ml is used to lower blood sugar levels when oral diabetes medications or other lifestyle changes are no longer sufficient to keep your diabetes under control.

Key Benefits

Nobeglar-Uno 100IU Prefilled Pen 3 ml provides long-lasting blood sugar control by delivering a steady supply of insulin throughout the day and night. By maintaining stable glucose levels and simplifying diabetes management, this medicine offers several key health benefits:

  • Steady 24-Hour Blood Sugar Control: Nobeglar-Uno 100IU Prefilled Pen 3 ml releases insulin slowly and consistently into the bloodstream, helping prevent sudden spikes and drops in blood sugar and providing reliable day-and-night glucose stability.
  • Protection Against Diabetes Complications: By helping maintain blood sugar within the target range, Nobeglar-Uno 100IU Prefilled Pen 3 ml reduces the risk of long-term diabetes-related complications, including nerve damage, kidney problems, vision loss, and cardiovascular concerns.
  • Convenient Daily Diabetes Management: With a simple once-daily injection schedule, Nobeglar-Uno 100IU Prefilled Pen 3 ml helps meet your background insulin requirements consistently, making daily diabetes care easier and more manageable.
     

Directions for Use

Always follow your doctor's exact instructions regarding your dose and how to inject Nobeglar-Uno 100IU Prefilled Pen 3 ml. Do not change your dose or stop using this medication without consulting your healthcare provider first.

  • Inject Nobeglar-Uno 100IU Prefilled Pen 3 ml under the skin (subcutaneously) of your thigh, upper arm, or abdomen.
  • Never inject this medication into a vein or a muscle, as this can cause the insulin to act too quickly and lead to dangerously low blood sugar.
  • Rotate your injection site with every dose to prevent skin changes, such as lumps or thinning of the fat under the skin.
  • Do not mix Nobeglar-Uno 100IU Prefilled Pen 3 ml in the same syringe with any other insulin, and do not dilute it with other liquids.

How Nobeglar-Uno 100IU Prefilled Pen 3 ml Works

Nobeglar-Uno 100IU Prefilled Pen 3 ml contains insulin glargine. It works by mimicking the natural, steady background release of insulin that a healthy pancreas normally provides. Once injected under the skin, the solution forms micro-crystals in the fatty tissue. These crystals dissolve very slowly over time, releasing a constant, low level of insulin into your bloodstream over 24 hours. Once in your blood, the insulin acts like a key that allows your body's cells to absorb sugar (glucose) from your bloodstream to use for energy. At the same time, it stops your liver from producing and releasing excess sugar into your blood, keeping your overall blood glucose levels stable and within a safe range.
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Nobeglar-Uno 100IU Prefilled Pen 3 ml to avoid unpleasant side effects.

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Pregnancy

Safe if prescribed

Nobeglar-Uno 100IU Prefilled Pen 3 ml can be used during pregnancy. Your insulin dose may need to be changed during pregnancy and after delivery. Please consult your doctor before taking Nobeglar-Uno 100IU Prefilled Pen 3 ml.

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Breast Feeding

Safe if prescribed

Nobeglar-Uno 100IU Prefilled Pen 3 ml can be given safely to nursing mothers but only under the supervision of a physician. Your physician may make adjustments in your insulin doses and your diet.

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Driving

Caution

Drive with caution, Nobeglar-Uno 100IU Prefilled Pen 3 ml usually causes drowsiness and affects driving ability. Your ability to concentrate and react may be reduced if you have hypoglycaemia (low blood sugar).

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Liver

Caution

Nobeglar-Uno 100IU Prefilled Pen 3 ml to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Nobeglar-Uno 100IU Prefilled Pen 3 ml to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Safe if prescribed

Nobeglar-Uno 100IU Prefilled Pen 3 ml can be given safely to children provided the dose is prescribed by a child specialist.

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Heart

Caution

Nobeglar-Uno 100IU Prefilled Pen 3 ml should be administered with caution in patients with heart problems. Please inform your doctor about any existing heart problems before using Nobeglar-Uno 100IU Prefilled Pen 3 ml.

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Geriatrics

Caution

Nobeglar-Uno 100IU Prefilled Pen 3 ml should be administered with caution in elderly patients. If you have any concerns, please consult your doctor.

What if I have taken an overdose of Nobeglar-Uno 100IU Prefilled Pen 3 ml

Do not take more than the prescribed dose of Nobeglar-Uno 100IU Prefilled Pen 3 ml as it may cause overdose and lead to low blood sugar. If you suspect you have taken an overdose or have symptoms of low blood sugar or other symptoms such as seizures (fits) or loss of consciousness, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Track your carbohydrate intake: Maintain a consistent daily intake of carbohydrates to help keep your blood sugar levels predictable and prevent sudden drops.
  • Always carry fast-acting sugar: Keep a source of quick sugar with you at all times, such as glucose tablets, fruit juice, or hard candies, to treat sudden low blood sugar quickly.
  • Exercise safely: Physical activity lowers blood sugar. Test your blood sugar levels before, during, and after exercise, and discuss with your doctor if you need to adjust your food intake or dose.
  • Monitor blood sugar regularly: Test your blood sugar levels as directed by your healthcare team to understand how your body is responding to the medication
  • Stay hydrated: Drink plenty of water throughout the day, especially in hot weather or during physical activity, as dehydration can affect your blood sugar control.

Have a query?

How Soon It Starts Working

The time required for Nobeglar-Uno 100IU Prefilled Pen 3 ml to start to work: Nobeglar-Uno 100IU Prefilled Pen 3 ml ideally shows its action within 1.5 to 2 hours after administration. The time for which the effects of Nobeglar-Uno 100IU Prefilled Pen 3 ml last: The effect of Nobeglar-Uno 100IU Prefilled Pen 3 ml lasts for 24 hours.

What if you forget to take Nobeglar-Uno 100IU Prefilled Pen 3 ml

If you are using this medication on a regular schedule and you miss a dose but remember within 2 hours, use it as soon as you remember. If it has been more than 2 hours, consult your doctor. Do not double the dose to catch up.

Storage

• Store unused, unopened Nobeglar-Uno 100IU Prefilled Pen 3 ml vials or injection pens in the refrigerator between 2°C and 8°C. •Do not freeze this medication, and discard it immediately if it has been frozen.
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Keep Refrigerated. Do not freeze.Prepaid payment required.

Drug Warnings

  • Always inspect the liquid inside the vial or pen before injecting; it must be completely clear and colorless. Do not use it if it looks cloudy, colored, or has floating particles.
  • Never share your Nobeglar-Uno 100IU Prefilled Pen 3 ml injection pen, needle, or syringe with anyone else, even if the needle has been changed, to avoid spreading serious infections.
  • Always use a new, sterile needle for every injection to prevent infections and avoid blocked needles.
  • Rotate your injection site within your chosen area (thigh, arm, or stomach) with each dose to prevent hard lumps or skin damage from developing.
  • Check your blood sugar before driving, operating machinery, or performing tasks that require concentration, as low blood sugar can impair your coordination and alertness.

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Drug-Drug Interactions:

Inform your doctor if you are taking any of the following medicines, as they may interact.

  • May increase the risk of low blood sugar when combined with other diabetes medicines (such as sulfonylureas), certain blood pressure drugs (such as ACE inhibitors), or certain antidepressants (such as MAO inhibitors).
  • May decrease the effectiveness of Nobeglar-Uno 100IU Prefilled Pen 3 ml, leading to high blood sugar, when taken with corticosteroids (such as prednisone), thyroid hormones, or certain atypical antipsychotics.
  • Certain blood pressure medications (such as beta-blockers) may mask the common warning signs of low blood sugar, such as a rapid heart rate, sweating, or palpitations.

Drug-Food Interactions:

  • Drinking alcohol can unpredictably affect your blood sugar levels, either causing a sudden drop or prolonging the risk of severe low blood sugar.

Drug-Disease Interactions:

Inform your doctor if you have a history of the following conditions before taking Nobeglar-Uno 100IU Prefilled Pen 3 ml, as it may worsen your condition or cause complications.

  • Kidney or Liver Damage: May require a gradually decreasing dose because your body may process and clear the insulin more slowly, increasing the risk of low blood sugar.
  • Heart Failure: Taking Nobeglar-Uno 100IU Prefilled Pen 3 ml alongside certain oral diabetes medicines (such as thiazolidinediones) may cause your body to retain fluid, which can worsen heart failure.
     

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FAQs

Nobeglar-Uno 100IU Prefilled Pen 3 ml is used to treat type 1 diabetes in adults and children and type 2 diabetes mellitus in adults.
Nobeglar-Uno 100IU Prefilled Pen 3 ml works by replacing the insulin that is normally produced by the body. It helps move sugar from the blood into other body tissues where it is used for energy. Nobeglar-Uno 100IU Prefilled Pen 3 ml also prevents the liver from producing more sugar.
Nobeglar-Uno 100IU Prefilled Pen 3 ml should be stored in a refrigerator (2°C-8°C). Do not freeze.
Type-2 diabetes generally does not affect healthy children and teens, but it may affect children who are obese, which is also known as Childhood Obesity.
Cut back on foods high in sodium, alcohol, fried foods, and high-carb food and drinks like sugary drinks, drinks with added sugar, white rice and starchy vegetables.
Nobeglar-Uno 100IU Prefilled Pen 3 ml should not be discontinued without a doctor's consultation as stopping Nobeglar-Uno 100IU Prefilled Pen 3 ml may cause severe hypoglycaemia (low blood sugar) and ketoacidosis (buildup of acid in the blood). Consult the doctor if you feel uncomfortable after taking Nobeglar-Uno 100IU Prefilled Pen 3 ml.
The injection site should be changed to prevent skin changes like lumps under the skin. Nobeglar-Uno 100IU Prefilled Pen 3 ml may not work well if injected into the lumpy area.
Maintain a healthy diet and exercise regularly. Limit sugar intake and avoid smoking & alcohol consumption. Manage stress by doing meditation or yoga.
Hypoglycaemia (low blood sugar) may occur because you inject too much insulin, miss or delay meals, do not eat enough, eat food containing less carbohydrate than normal, drink alcohol, lose carbohydrates due to vomiting or diarrhoea, do more exercise than usual or a different type of physical activity, are recovering from an injury, illness, operation or stress, or are taking/have stopped taking other medicines.
Nobeglar-Uno 100IU Prefilled Pen 3 ml contains insulin glargine, a modified insulin which is very similar to human insulin.
Check the label for directions and use Nobeglar-Uno 100IU Prefilled Pen 3 ml as advised by the doctor. Talk to the doctor if you have any concerns. Fill the injection with the appropriate dose. Pick the injection site and wipe it with an alcohol swab. Now, pinch up the skin, inject the needle into the skin and then push the plunger in. After injecting the insulin, pull out the needle and dispose of the syringe safely.
Nobeglar-Uno 100IU Prefilled Pen 3 ml should be used only as prescribed by the doctor. The doctor will recommend the dose and duration based on your condition.
Using more than the prescribed dose of Nobeglar-Uno 100IU Prefilled Pen 3 ml may cause hypoglycaemia (low blood sugar). Monitor blood glucose levels and consult the doctor if the blood sugar levels are low.
The dose of Nobeglar-Uno 100IU Prefilled Pen 3 ml may need to be changed based on your blood sugar levels, lifestyle conditions, if are taking certain other medicines, during pregnancy, after giving birth, and breastfeeding.
Serious side effects of Nobeglar-Uno 100IU Prefilled Pen 3 ml include severe allergic reactions (rash/itching all over the body, severe swelling of skin or mucous membrane, shortness of breath, a fall in blood pressure with rapid heartbeat and sweating) and hypoglycaemia (thirst, tiredness, increased urge to urinate, tiredness, fast heartbeat, and low blood pressure). Seek immediate medical attention if you experience these symptoms.
Nobeglar-Uno 100IU Prefilled Pen 3 ml can be given to treat both the conditions of type 1 and type 2 diabetes mellitus. However, your doctor will decide whether Nobeglar-Uno 100IU Prefilled Pen 3 ml can be given to you or not, depending on your present condition. Nobeglar-Uno 100IU Prefilled Pen 3 ml should be avoided in patients who are allergic to Nobeglar-Uno 100IU Prefilled Pen 3 ml or other forms of insulin. It should be avoided in patients suffering from low potassium level (hypokalemia), moderate to severe kidney disease or liver disease. Inform the doctor if you are pregnant or breastfeeding.
No. You must never mix Nobeglar-Uno 100IU Prefilled Pen 3 ml with any other insulin or liquid in the same syringe. Mixing it can change how the medication is absorbed, preventing it from working correctly and potentially causing dangerous blood sugar fluctuations. Talk to your doctor if you require multiple types of insulin.
You should inject Nobeglar-Uno 100IU Prefilled Pen 3 ml once a day, at the exact same time every day. Your doctor will help you decide whether a morning or evening injection fits your lifestyle and treatment needs best. Talk to your doctor or pharmacist if you need help establishing a routine.
If you experience symptoms of low blood sugar and are able to swallow safely, consume 15 grams of fast-acting sugar immediately, such as a half-cup of fruit juice, three glucose tablets, or a few hard candies. Wait 15 minutes, check your blood sugar again, and repeat if it is still too low. Talk to your doctor if you experience frequent low blood sugar episodes.
Yes, you can travel with your medication. Keep unopened vials or pens cool by using an insulated travel bag with cold packs, making sure they do not touch ice directly to prevent freezing. Always carry your active, in-use pen or vial in your hand luggage rather than checked baggage to protect it from extreme temperature changes in the cargo hold. Talk to your doctor for a travel letter if needed.
No, you do not need to eat a meal immediately after injecting Nobeglar-Uno 100IU Prefilled Pen 3 ml because it is a long-acting insulin that provides a steady, continuous release over 24 hours. However, you must still maintain your regular, scheduled meals throughout the day to keep your blood sugar balanced. Talk to your doctor or pharmacist about how to align your meals with your injection.
No. If your medication has been frozen, even if it has thawed out, you must discard it immediately. Freezing damages the structure of the medicine, making it ineffective and unsafe for controlling your blood sugar. Always store your medication in the main compartment of the refrigerator, away from the freezer element.
Injecting this medication into a muscle can cause your body to absorb the medicine much faster than intended. This can lead to a sudden, severe drop in your blood sugar. Monitor your blood sugar levels closely, keep fast-acting sugar nearby, and seek medical help if your blood sugar drops dangerously low. Talk to your doctor or pharmacist if you are unsure about proper injection techniques.
Keeping your blood sugar well-controlled is highly important during pregnancy for both you and your baby. Nobeglar-Uno 100IU Prefilled Pen 3 ml is commonly used during pregnancy, but your insulin requirements may change significantly during this time. Talk to your doctor to discuss how to adjust your dose and safely manage your blood sugar throughout your pregnancy.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.7920 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  2. Drugs.com Clinical Review Team. Insulin Glargine Drug Interactions Reference. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  3. Insulin glargine [EMC Label]. 2018. [Accessed on 12 Mar. 2019] Check here
  4. Insulin Glargine [FDA Prescription Information]. 2013. [Accessed on 08 Oct. 2021] Check here
  5. Insulin glargine injection [Prescribing Information]. 2021. [Accessed on 05 Jul. 2023] Check here
  6. Ema.insulin glargine. [[Accessed on 26.June].2019] Check here
  7. Lactmed.insulin glargine. [[Accessed on 26.June].2019] Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Insulin. [Updated 2018 Oct 31]:Check here

Country of origin

India

Manufacturer/Marketer address

208, Okhla Industrial Estate, Phase 3, New Delhi - 110020.
Other Info - NOB0069

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