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compositionComposition:NIMESULIDE-100MG+PARACETAMOL-325MG+TIZANIDINE-2MG
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Prescription Medicine
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NOBEL MR 2MG TABLET is used to relieve pain due to muscle spasms, headaches, migraine, rheumatic pain, backache, and period pain. It works by blocking the chemical messengers that cause pain and relieving muscle spasms. In some cases, this medicine may cause side effects such as nausea, vomiting, dizziness, dry mouth, and diarrhoea. Let the doctor know if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

NIMESULIDE-100MG+PARACETAMOL-325MG+TIZANIDINE-2MG

Manufacturer/Marketer :

Mankind Pharma Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About NOBEL MR 2MG TABLET

NOBEL MR 2MG TABLET is an oral medication prescribed to treat painful muscle spasms and the discomfort associated with stiff musculoskeletal conditions. It helps ease severe muscle tension, reduce swelling, and alleviate acute pain in the back, neck, or joints. This medicine is designed to restore comfortable movement so you can resume your daily routine.

To get the best results, you should take this medicine consistently and exactly at the frequency prescribed by your doctor, typically for a short duration. It is highly recommended to take NOBEL MR 2MG TABLET with food or a glass of milk to protect your stomach lining from irritation. Combining this treatment with gentle daily stretches, staying well-hydrated, and getting adequate rest can significantly improve your recovery.

While taking NOBEL MR 2MG TABLET, you may experience common side effects such as drowsiness, a dry mouth, or mild stomach upset. However, you must contact your doctor immediately if you notice serious symptoms like yellowing of your eyes or skin, dark urine, severe stomach pain, or an unusual skin rash.

Before starting this medicine, tell your doctor if you have a history of stomach ulcers, kidney problems, or heart conditions. Do not take this if you have active liver disease, severe bleeding disorders, or if you have ever had an allergic reaction to other pain-relievers.

This medicine can interact with alcohol, which increases the risk of liver damage and extreme sleepiness, as well as blood thinners and other pain medications. Elderly individuals, pregnant women, and breastfeeding mothers must consult their doctor before using NOBEL MR 2MG TABLET to ensure safety.

Uses of NOBEL MR 2MG TABLET

NOBEL MR 2MG TABLET is used to treat painful muscle spasms and the discomfort associated with stiff musculoskeletal conditions. The detailed uses of NOBEL MR 2MG TABLET are as follows:

  • Painful muscle spasms: Eases sudden, involuntary muscle contractions and stiffness in the back, neck, or other skeletal muscles.
  • Musculoskeletal pain: Reduces swelling, tenderness, and acute pain in joints and muscles, making daily physical movements easier.

Key Benefits

Using NOBEL MR 2MG TABLET provides rapid, multi-action relief by addressing both muscle tightness and underlying pain at the same time. This comprehensive approach helps break the painful cycle of muscle spasm and stiffness, allowing you to move more freely and comfortably.

By easing severe muscle tension, this medication helps you engage in physical therapy, gentle stretching, and daily tasks with minimal discomfort. This speeds up your overall recovery time and helps you return to your active lifestyle sooner. 

Side effects of Nobel Mr 2mg Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Consume more fruits, vegetables, and cruciferous foods like cabbage, kale, and broccoli.
  • Reduced alcohol intake can enhance liver enzyme function.
  • Oxidative stress can be managed by eating foods rich in antioxidants, such as vitamins C and E.
  • Liver function tests regularly can help manage increased levels of AST.

Directions for Use

  • Take NOBEL MR 2MG TABLET with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow it as a whole with a glass of water.
  • Do not crush, chew or break it.

How NOBEL MR 2MG TABLET Works

NOBEL MR 2MG TABLET works through a combination of three active ingredients that target pain and muscle stiffness from different angles. Together, they block pain signals, reduce inflammation, and relax tight muscle fibres. The first active component, tizanidine, is a muscle relaxant that works directly on the central nervous system. It acts on the brain and spinal cord to reduce muscle tone and ease painful spasms, allowing tight muscles to relax. The second active component, nimesulide, is a specialised anti-inflammatory agent. It stops the body from producing certain natural chemical messengers that trigger pain, swelling, and redness at the site of the muscle injury. The third active component, paracetamol, is a widely trusted pain reliever. It works centrally in the brain to block pain signals from being processed, while also helping to lower any fever associated with your condition.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking NOBEL MR 2MG TABLET as it may cause increased drowsiness. It can also increase the risk of stomach bleeding.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks. NOBEL MR 2MG TABLET should not be taken during the last three months of pregnancy.

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Breast Feeding

Caution

Consult your doctor before taking NOBEL MR 2MG TABLET, your doctor will decide whether NOBEL MR 2MG TABLET can be taken by breastfeeding mothers or not.

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Driving

Caution

NOBEL MR 2MG TABLET may cause dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

NOBEL MR 2MG TABLET should not be given to children as safety and effectiveness were not established.

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Heart

Caution

NOBEL MR 2MG TABLET is generally not prescribed for heart patients due to an increased risk of side effects. Please consult your doctor before using NOBEL MR 2MG TABLET.

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Geriatrics

Caution

Limited data is available regarding the use of NOBEL MR 2MG TABLET in elderly patients. If you have any concerns about the usage of NOBEL MR 2MG TABLET in geriatrics, please consult your doctor.

What if I have taken an overdose of NOBEL MR 2MG TABLET

If you take too much of this medicine, seek immediate medical attention. Symptoms of an overdose may include severe drowsiness, extreme dizziness, nausea, vomiting, or stomach pain.

Diet & Lifestyle Advise

  • Stay hydrated: Drink plenty of water throughout the day to help ease dry mouth and keep your muscle tissues healthy.
  • Practice gentle movement: Avoid prolonged bed rest. Engage in light stretching or gentle walking as advised by your physical therapist to prevent further muscle stiffness.
  • Apply heat or cold: Use warm compresses or ice packs on the affected muscle for 15 to 20 minutes at a time to soothe pain and decrease local inflammation.
  • Avoid heavy physical strain: Refrain from heavy lifting, sudden twisting, or intense workouts while your muscles are recovering. 
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How Soon It Starts Working

The time required for NOBEL MR 2MG TABLET to start to work: NOBEL MR 2MG TABLET ideally shows its action within 1 to 2 hours after administration. The time for which the effects of NOBEL MR 2MG TABLET last: The effect of NOBEL MR 2MG TABLET lasts for 6 to 10 hours.

What if you forget to take NOBEL MR 2MG TABLET

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed one.

Storage

• Store this medicine at room temperature between 15°C and 30°C.

Drug Warnings

  • Avoid driving, riding a bicycle, or operating heavy machinery until you know how this medicine affects you, as it can cause significant drowsiness and dizziness.
  • Do not take any other medications containing paracetamol or similar pain relievers while using this medicine to avoid accidental overdose and severe liver damage.
  • Avoid drinking alcohol while taking this medicine, as it greatly increases the risk of severe liver damage and extreme sleepiness.
  • If your muscle pain and stiffness do not begin to improve within a few days of starting this medicine, contact your doctor for advice. 

Drug-Drug Interactions

verifiedApollotooltip
  • Blood thinners: May increase the risk of stomach bleeding when taken with medicines like warfarin.
  • Other central nervous system depressants: May increase drowsiness and dizziness when combined with sleeping pills, anxiety medications, or other muscle relaxants.
  • Blood pressure medicines: May reduce the effectiveness of blood pressure drugs or increase the risk of kidney issues.
  • Certain antibiotics and heart medicines: May interact and increase the risk of side effects. Always inform your doctor of all medicines you are taking.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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  • Food: Taking this medicine with a meal or milk reduces stomach irritation without affecting how well the medicine works.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANALGESICS]

FAQs

NOBEL MR 2MG TABLET is used to relieve pain due to muscle spasms such as arthritis, muscle pain, tooth pain, bone and joint pain, headache, and period pain.
NOBEL MR 2MG TABLET contains Nimesulide, Paracetamol, and Tizanidine. Nimesulide and Paracetamol work by blocking the effect of chemical messengers that cause pain and inflammation at the injured or damaged site. Tizanidine works on the centres of the spinal cord and brain, which helps relieve muscle stiffness, thereby improving muscle movements. Together, NOBEL MR 2MG TABLET helps in reducing pain due to muscle spasms.
Diarrhoea might be a side-effect of NOBEL MR 2MG TABLET. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if the condition persists or worsens.
NOBEL MR 2MG TABLET should not be taken for longer durations unless prescribed by the doctor. Use the minimum effective dose for the shortest duration.
Dry mouth could be a side-effect of NOBEL MR 2MG TABLET. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevents drying of the mouth.
Taking NOBEL MR 2MG TABLET can elevate symptoms of gastric ulcer and bleeding. So, talk to your doctor before taking NOBEL MR 2MG TABLET if you have gastrointestinal bleeding or other bleeding problems like haemophilia before using NOBEL MR 2MG TABLET.
This medicine can cause drowsiness, dizziness, and blurred vision. It is safest to avoid driving or operating machinery until you know how it affects you. Talk to your doctor if you have concerns.
It is highly recommended to take this medicine with food or a glass of milk to protect your stomach lining and avoid irritation. Talk to your doctor or pharmacist for personalised advice.
This medicine is generally not recommended during pregnancy, especially in the third trimester, as it may affect the baby. Always talk to your doctor before starting any new medication if you are pregnant or planning to become pregnant.
You should avoid alcohol while taking this medicine. Alcohol increases the risk of severe liver damage and can make drowsiness or dizziness much worse. Talk to your doctor or pharmacist if you have questions about alcohol use.
Take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one. Do not take a double dose to make up for a missed one. Talk to your doctor or pharmacist if you frequently miss doses.
Do not take other pain relievers, especially those containing paracetamol or nonsteroidal anti-inflammatory drugs, without consulting your healthcare provider, as this can lead to an accidental overdose or severe side effects. Talk to your doctor or pharmacist before combining medicines.
This medicine is not considered addictive when used exactly as prescribed for short-term muscle spasm relief. Always follow your doctor's instructions and do not take it for longer than recommended. Talk to your doctor if you have any history of substance abuse.

Disclaimer

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Country of origin

India

Manufacturer/Marketer address

208, Okhla Industrial Estate, Phase III, New Delhi - 110020
Other Info - NOB0020

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