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More about the Product

Composition :

CHLORPHENIRAMINE MALEATE-2MG+PHENYLEPHRINE-2MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Nocold Syrup

Nocold Syrup is used to treat symptoms caused by the common cold, flu, allergies and other breathing problems like sinusitis and bronchitis. An allergy is an immune system response to foreign elements known as allergens.

Nocold Syrup contains Chlorpheniramine maleate and Phenylephrine. Chlorpheniramine maleate blocks the release of histamine in the body, which is known to cause allergic symptoms. Phenylephrine helps shrink the blood vessels in the nasal passage, thereby reducing the stuffy nose.

Take Nocold Syrup as advised by your doctor. The side effects of Nocold Syrup include drowsiness, dizziness, headache, dry mouth/nose/throat, upset stomach, constipation, or trouble sleeping. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Inform your doctor if you are allergic to any of the components of Nocold Syrup. Please tell your doctor before starting Nocold Syrup if you have a liver problem, are pregnant, or are breastfeeding. Nocold Syrup may cause drowsiness and sleepiness, so it is advised not to drive or operate machinery.

Uses of Nocold Syrup

Nocold Syrup is used in the treatment of the Common cold and Allergies. The detailed uses of Nocold Syrup are as follows:

  • Cold Symptom Management: Nocold Syrup is effective in managing common cold symptoms such as throat irritation and nasal congestion, providing relief and comfort during illness.
  • Allergy Symptom Relief: Nocold Syrup may also alleviate symptoms of allergies, including sneezing and a runny nose, making it particularly useful for managing seasonal allergies.

Key Benefits

  • It helps improve breathing, restore nasal airflow, and enhance overall comfort during colds or allergic episodes.
  • Reduces the symptoms of allergies, such as a runny nose, watery eyes, and sneezing.
  • Reduces nasal congestion by causing the nose's enlarged blood vessels to contract.
  • Relieves congestion and sinus pressure.
  • Relieves allergic rhinitis and the common cold.
  • Enhances general comfort and nasal breathing.
Side effects of Nocold Syrup 60 ml
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Directions for Use

  • Nocold Syrup can be taken with or without food. However, if it causes stomach upset, it is advisable to take it with food to minimise discomfort.
  • Follow your doctor’s instructions on dosage and timing.
  • Swallow it as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Nocold Syrup Works

Nocold Syrup contains two medicines, namely, chlorpheniramine maleate (antihistamine/antiallergic) and phenylephrine (decongestant). • Chlorpheniramine maleate blocks the release of histamine in the body, which is known to cause allergic symptoms. • Phenylephrine helps shrink the blood vessels in the nasal passage, thereby reducing the stuffy nose. • Together, Nocold Syrup effectively reduces allergic symptoms.
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Alcohol

Caution

Nocold Syrup may cause excessive dizziness when taken with alcohol, so alcohol intake should be avoided.

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Pregnancy

Consult your doctor

Consult your doctor if you are pregnant or planning a pregnancy. Nocold Syrup should be used only if the doctor prescribes it.

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Breast Feeding

Consult your doctor

Please consult the doctor before taking the Nocold Syrup if you are breastfeeding. Your doctor will prescribe only if the benefits outweigh the risks.

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Driving

Caution

Nocold Syrup is known to cause drowsiness and sleepiness. So, drive only if you are alert.

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Liver

Caution

Nocold Syrup to be taken with caution, especially if you have a history of liver disease. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Nocold Syrup to be taken with caution, especially if you have a history of kidney disease. The dose may have to be adjusted by your doctor.

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Children

Caution

Nocold Syrup is not recommended for children below the age of 4 years. For children aged four years and above, use Nocold Syrup only when prescribed by a child specialist.

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Heart

Caution

Nocold Syrup should be taken with caution in patients with heart conditions. Please inform your doctor about any existing heart problems before starting Nocold Syrup.

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Geriatrics

Caution

Nocold Syrup should be given with caution in elderly patients due to an increased risk of side effects. Please consult your doctor before using Nocold Syrup.

What if I have taken an overdose of Nocold Syrup

Do not take more than the prescribed dose of Nocold Syrup as it may cause an overdose. The symptoms of overdose include fainting, seizures (fits), hallucinations or irregular heartbeat. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

Healthy eating habits:

  • To prevent dryness and discomfort in your stomach, eat light, balanced meals that include fruits, vegetables, and whole grains.
  • To stay hydrated and lessen dryness in your throat and nose, drink lots of water and warm liquids.
  • Steer clear of alcohol and excessive caffeine since these can exacerbate dehydration and tiredness.
  • If you have nausea or acidity after taking the medication, limit foods that are extremely hot or greasy.

Lifestyle changes:

  • To aid in your body's recovery from cold or allergy symptoms, get enough sleep.
  • Avoid exposure to smoking, dust, cold air, and other allergens that can exacerbate symptoms.
  • To relieve nasal congestion, use steam inhalation and keep your home humid.
health query

Have a query?

How Soon It Starts Working

  • The time required for Nocold Syrup to start to work: The time required for Nocold Syrup to show its action is unknown.
  • The time for which the effects of Nocold Syrup last: The duration of action for Nocold Syrup is clinically unknown.

What if you forget to take Nocold Syrup

If you forget to take a dose of Nocold Syrup, take it as soon as you remember. However, if it is nearly time for your next scheduled dose, skip the missed one and go back to your usual dosing routine. Avoid taking two doses at once to make up for the missed dose.

Storage

• Store in a cool and dry place away from sunlight.• Keep Nocold Syrup out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Do not take Nocold Syrup if you are allergic to any of its ingredients or if you have taken an MAO inhibitor (antidepressant medication) in the past 14 days.
  • Please consult your doctor if you are pregnant or breastfeeding before starting Nocold Syrup.
  • Inform your doctor if you have cardiovascular disease, asthma, kidney or liver disease, diabetes, glaucoma, chronic obstructive pulmonary disease, or benign prostatic hyperplasia.
  • Let your doctor know about all other medications you have taken before starting Nocold Syrup.
  • Nocold Syrup may cause drowsiness and sleepiness, so it is advised not to drive or operate machinery unless you are alert.
  • Consumption of alcohol should be avoided as it may lead to excessive drowsiness and sleepiness.
  • If you are due to undergo any surgery, please inform your doctor that you are taking Nocold Syrup, as it should not be taken during surgery.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions: Taking Nocold Syrup with the following medication classes may cause adverse reactions.

  • Anti-depressant drugs (Amitriptyline, Nortriptyline)
    • Potential effect: May cause increased blood pressure. Should be avoided or used in an emergency only if prescribed by the physician.
  • Antibiotics (Furazolidone, Linezolid)
    • Potential effect: May cause increased blood pressure. Should be avoided or used in an emergency only if prescribed by the physician.
  • MAO Inhibitors (Selegiline, Isocarboxazid)
    • Potential effect: May cause severe increased blood pressure. Should be avoided or used in an emergency only if prescribed by the physician.

Drug-Food Interactions: Alcohol should not be used along with Nocold Syrup.

Drug-Disease Interactions: Inform your doctor if you have a history of the following conditions before taking Nocold Syrup, as it may worsen your condition or cause complications.

  • Cardiovascular disease
  • Asthma
  • Kidney or liver disease
  • Diabetes
  • Glaucoma
  • Chronic obstructive pulmonary disease
  • Benign prostatic hyperplasia (BPH) or enlarged prostate gland,
  • Intestinal ulcer or blockage.
Chlorpheniramine + PhenylephrinePropofol
Critical
Chlorpheniramine + PhenylephrineFurazolidone
Critical

Drug-Drug Interactions

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Chlorpheniramine + PhenylephrinePropofol
Critical
How does the drug interact with Nocold Syrup 60 ml:
Taking Nocold Syrup 60 ml with Propofol lowers metabolism, which raises phenylephrine levels. Additionally, it can increase or decrease sleepiness when taken together.

How to manage the interaction:
Taking Nocold Syrup 60 ml with Propofol is not recommended, as it leads to an interaction, but it can be taken if prescribed by a doctor. Do not discontinue the medications without consulting a doctor.
Chlorpheniramine + PhenylephrineFurazolidone
Critical
How does the drug interact with Nocold Syrup 60 ml:
Taking Nocold Syrup 60 ml with Furazolidone can cause an increase in high blood pressure.

How to manage the interaction:
Taking Nocold Syrup 60 ml with Furazolidone is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden headaches, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sweating, lightheadedness, fainting, sudden numbness or weakness (especially on one side of the body), speech difficulties, or fever, consult a doctor immediately. It is advised to use Phenylephrine only after 14 days of stopping Furazolidone. Do not stop using any medications without a doctor’s advice
Chlorpheniramine + PhenylephrineSelegiline
Critical
How does the drug interact with Nocold Syrup 60 ml:
Co-administration of Nocold Syrup 60 ml with Selegiline can raise blood pressure.

How to manage the interaction:
Taking Nocold Syrup 60 ml with Selegiline is not recommended, it can be taken together if prescribed by a doctor. However, consult a doctor immediately if you experience any symptoms such as severe headache, blurred vision, confusion, fits, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting. Do not discontinue any medications without consulting a doctor.
Chlorpheniramine + PhenylephrineIsocarboxazid
Critical
How does the drug interact with Nocold Syrup 60 ml:
Co-administration of Nocold Syrup 60 ml with Isocarboxazid can result in extremely high blood pressure.

How to manage the interaction:
Although taking Nocold Syrup 60 ml together with Isocarboxazid is not recommended as it can result in an interaction, it can be taken if prescribed by a doctor. However, if you develop a sudden, severe headache, blurred vision, confusion, chest pain, nausea, or vomiting, sudden numbness or weakness (particularly on one side of the body), difficulty speaking, fever, sweating, lightheadedness, or fainting, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
Chlorpheniramine + PhenylephrineMethylene blue
Critical
How does the drug interact with Nocold Syrup 60 ml:
Taking Nocold Syrup 60 ml with Methylene blue can cause an increase in high blood pressure.

How to manage the interaction:
Taking Nocold Syrup 60 ml with Methylene blue is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden headaches, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sweating, lightheadedness, fainting, sudden numbness or weakness (especially on one side of the body), speech difficulties, or fever, consult a doctor immediately. It is advised to use Phenylephrine only after 14 days of stopping Methylene blue. Do not stop using any medications without a doctor’s advice.
Chlorpheniramine + PhenylephrineTranylcypromine
Critical
How does the drug interact with Nocold Syrup 60 ml:
Taking Nocold Syrup 60 ml with Tranylcypromine can increase the risk of high blood pressure.

How to manage the interaction:
Taking Nocold Syrup 60 ml with Tranylcypromine is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe headaches, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and fainting. Do not discontinue any medications without consulting a doctor.
Chlorpheniramine + PhenylephrineLinezolid
Critical
How does the drug interact with Nocold Syrup 60 ml:
Co-administration of Nocold Syrup 60 ml together with Linezolid can lead to side effects like increased blood pressure.

How to manage the interaction:
Taking Nocold Syrup 60 ml together with Linezolid is not recommended as it can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe headaches, chest pain, dizziness, difficulty breathing, nausea, vomiting, blurred vision, or anxiety, consult a doctor. Do not stop using any medications without a doctor’s advice.
Chlorpheniramine + PhenylephrinePotassium citrate
Critical
How does the drug interact with Nocold Syrup 60 ml:
Co-administration of Nocold Syrup 60 ml with potassium citrate can make potassium more irritating to your upper intestine and stomach.

How to manage the interaction:
Taking Nocold Syrup 60 ml with Potassium citrate is not recommended as it can lead to an interaction, it can be taken if prescribed by a doctor. However, if you experience any symptoms such as severe stomach pain, bloating, lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
Chlorpheniramine + PhenylephrineSevoflurane
Critical
How does the drug interact with Nocold Syrup 60 ml:
Co-administration of Nocold Syrup 60 ml with Isoflurane makes phenylephrine more harmful. Additionally, phenylephrine reduces sleepiness, and chlorpheniramine and sevoflurane promote sleepiness.

How to manage the interaction:
Co-administration of Nocold Syrup 60 ml with Sevoflurane is not recommended as it can result in an interaction, but it can be taken if prescribed by a doctor. However, if you experience severe headaches, chest pain, dizziness, difficulty breathing, nausea, vomiting, blurred vision, or anxiety, consult a doctor. Do not stop using any medications without a doctor’s advice. Do not discontinue any medications without a doctor's advice.
Chlorpheniramine + PhenylephrineMethoxyflurane
Severe
How does the drug interact with Nocold Syrup 60 ml:
Co-administration of Nocold Syrup 60 ml with Methoxyflurane makes phenylephrine more harmful. Additionally, Phenylephrine reduces and chlorpheniramine promotes sleepiness.

How to manage the interaction:
There may be a possibility of interaction between Phenylephrine and Methoxyflurane, but it can be taken if prescribed by a doctor. However, if you experience severe headaches, chest pain, dizziness, difficulty breathing, nausea, vomiting, blurred vision, or anxiety, consult a doctor. Do not stop using any medications without a doctor’s advice. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIALLERGIC]

FAQs

Nocold Syrup is used to treat symptoms caused by the common cold, flu, allergies and other breathing problems like sinusitis and bronchitis.
Nocold Syrup contains Chlorpheniramine maleate and Phenylephrine. Chlorpheniramine maleate blocks histamine in the body, which is known to cause allergic symptoms. Phenylephrine helps in shrinking the blood vessels in the nasal passage, thereby reducing the stuffy nose. Together, both of them effectively reduce the symptoms of a cold and allergies.
It is not recommended to take Nocold Syrup and any antidepressant medication, as it may lead to unpleasant side effects or drug interactions. Also, Nocold Syrup should be taken at least 15 days after your last dose of antidepressants.
Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take Nocold Syrup and skip the missed dose. Do not take extra medicine to make up for the missed dose.
Nocold Syrup is known to cause drowsiness and sleepiness. Hence, you are recommended to take it at night if you are experiencing excessive drowsiness during the day and avoid driving or doing anything that requires mental alertness.
The exact time may vary depending on the individual's condition and response to the medication. Follow your doctor's instructions carefully to achieve effective results.
Nocold Syrup is not an antibiotic. It is a combination medication that typically contains ingredients like chlorpheniramine, an antiallergic, and phenylephrine, a decongestant.
Nocold Syrup is an antiallergic medication typically containing ingredients like chlorpheniramine and phenylephrine. It is used to relieve cold and flu symptoms, such as fever, headache, and body pain.
Nocold Syrup is generally considered safe when used as prescribed by a doctor. However, like all medications, it can have side effects and potential interactions with other drugs. It's important to follow your doctor's instructions and inform them of any pre-existing and existing medical conditions or medication history to avoid adverse complications.
Nocold Syrup can sometimes cause nausea and vomiting as side effects, though not everyone experiences them as individual responses towards medication may vary. These effects are typically mild and temporary, resolving as the body adjusts to the medication. However, if these symptoms persist or worsen, it’s essential to consult a doctor promptly to ensure the safety and well-being of the individual.
No, you should not take a higher dose of Nocold Syrup than the recommended amount, as it can increase the risk of side effects and adverse health complications. Always follow the dosage your doctor prescribes or as indicated on the package. If you have any concerns about dosing, please discuss them with your doctor.
Yes, there are some contraindications related to the use of Nocold Syrup, such as avoiding using Nocold Syrup if you have an allergy to its ingredients, high blood pressure, severe heart disorders, overactive thyroid, kidney or liver problems, glaucoma, and urinary retention. Always consult your doctor before use.
Store Nocold Syrup in a cool, dry place, and out of sunlight. Keep it out of the reach of children.
The common side effects of Nocold Syrup that may occur in some individuals are drowsiness, dizziness, headache, dry mouth/nose/throat, upset stomach, constipation, or trouble sleeping. Most of these side effects of Nocold Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist, contact your doctor.
If you forget a dose of Nocold Syrup, take it immediately when you remember. However, if your next dose is near, skip the missed dose and continue with your regular schedule. Never double-dose to make up for a missed dose, as this may increase side effects.
If your symptoms persist or fail to improve, consult your doctor. Because the treatment process can be gradual, it may take some time to fully heal your condition. However, if you don't see improvement, your doctor may need to reassess your condition, adjust the dosage, or consider alternative treatments. Don't hesitate to consult your doctor with concerns or questions about your progress.
Don't stop taking your medication just because you're feeling better! This is a crucial moment in your recovery. Stopping too soon can lead to incomplete recovery and the return of symptoms. Instead, report your progress to your doctor and follow their advice. They will guide you on how to taper off the medication, if necessary, safely.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. MedlinePlus. A682543 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026]Check here
  2. Drugs.com Clinical Review Team. Chlorpheniramine Phenylephrine Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  3. MedlinePlus. A606008 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026]Check here
  4. U.S. Food and Drug Administration (FDA). 022113Orig1S000Medr [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  5. WebMD Medical Reference Review Board. Details Drug and Treatment Monograph. Atlanta, GA: WebMD; 2026. [Accessed on 02 Jun. 2026]Check here
  6. Chlorpheniramine maleate, phenylephrine HCl [Prescribing Information]. [Accessed on 18 Apr. 2019]Check here
  7. Chlorpheniramine Chlorpheniramine. 2016. [Accessed on 18 Apr. 2019]Check here

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013.
Other Info - NOC0013
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