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compositionComposition:METRONIDAZOLE-100MG+OFLOXACIN-50MG
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Nor-Metrogyl O Suspension is an antibiotic medicine used to treat bacterial infections in children. It contains Ofloxacin and Metronidazole. Ofloxacin works by inhibiting the repair of the bacterial cell wall (a protective covering) and causing damage to the bacterial cell wall. This eventually leads to the death of the bacterial cell and thus prevents the growth of bacterial infections. Metronidazole kills parasites and anaerobic bacteria that are responsible for causing infections. It works by damaging their DNA.

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Written By Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

METRONIDAZOLE-100MG+OFLOXACIN-50MG

Manufacturer/Marketer :

Lekar Pharma Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Nor-Metrogyl O Suspension

Nor-Metrogyl O Suspension is an antibiotic medicine used to treat bacterial infections in children. It is used in treating infections of the skin, throat, ear, and lungs caused by bacteria. It is also used in the treatment of dysentery (bloody stools) caused by amoeba. A bacterial infection occurs when harmful bacteria enter and grow in the body. This bacteria can infect any part of the body and multiply very quickly. Amoebic dysentery can be caused due to Entamoeba histolytica, Giardia lamblia, or Clostridium difficile.

Nor-Metrogyl O Suspension is a combination medicine containing Ofloxacin (fluoroquinolone) and Metronidazole (antimicrobials). Ofloxacin works by inhibiting the repair of the bacterial cell wall (a protective covering) and causing damage to the bacterial cell wall. This eventually leads to the death of the bacterial cell and thus prevents the growth of bacterial infections. Metronidazole kills parasites and anaerobic bacteria that are responsible for causing infections. It works by damaging their DNA.

Nor-Metrogyl O Suspension may cause certain side effects in your child such as indigestion, diarrhea, nausea, and stomach pain. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your paediatrician. Nor-Metrogyl O Suspension should be given as advised by your paediatrician. Do not give more than the prescribed dose of Nor-Metrogyl O Suspension to the child. Generally, the dose of the medicine will be decided by your paediatrician depending upon the type and severity of the infection.

Nor-Metrogyl O Suspension is intended for pediatric use only. Avoid giving Nor-Metrogyl O Suspension to your child if she/he is allergic to antibiotics. Keep your doctor informed about your child’s health condition including his current medications and medical history to rule out any side effects/interactions. Before administration, let your paediatrician know if your child has lung disease, muscle weakness, liver, and kidney disease.

Uses of Nor-Metrogyl O Suspension

Nor-Metrogyl O Suspension is used in the treatment of bacterial infections and amoebic dysentry. The detailed uses of Nor-Metrogyl O Suspension are as follows:

  • Tooth abscesses and gum infections: Nor-Metrogyl O Suspension is used in the treatment of tooth abscesses and gum infections.
  • Treatment of Gastrointestinal infections: Nor-Metrogyl O Suspension is used in the treatment of gastrointestinal infections such as diarrhoea and dysentery.
  • Treatment of bacterial and parasitic infections:Nor-Metrogyl O Suspension is used in the treatment of various infections like lung infections, urinary tract infections and genital tract infections.

Key Benefits

Nor-Metrogyl O Suspension contains Ofloxacin and Metronidazole (antimicrobials). Both these drugs are broad-spectrum antibiotics that act against aerobic (grow in the presence of oxygen) and anaerobic (grow in the absence of oxygen) bacteria. Nor-Metrogyl O Suspension is used in the treatment of several bacterial infections and amoebic dysentry in children. Ofloxacin works by inhibiting the repair of the bacterial cell wall (a protective covering) and causing damage to the bacterial cell wall. This eventually leads to the death of the bacterial cell and thus prevents the growth of bacterial infections. Metronidazole works by damaging the DNA. This kills parasites and anaerobic bacteria that are responsible for causing infections.

Side effects of Nor-Metrogyl O Suspension 60ml
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
  • Manage stress by practising deep breathing, yoga or meditation.
  • Participating in activities you enjoy, or exercising may also help manage agitation.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Exercise regularly. Try physical activities like walking, running, or dancing.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
  • Eat a balanced diet rich in fruits, vegetables, and whole grains to support overall health.
  • Include foods high in omega-3 fatty acids, like salmon and walnuts, to support eye health.
  • Stay hydrated by drinking plenty of water.
  • Engage in regular physical activity, like walking or yoga, to improve mobility and balance.
  • Practice stress-reducing techniques, like meditation or deep breathing, to manage emotional challenges.
  • Establish a daily routine to maintain independence and organization.
  • Consider learning Braille or using assistive technologies to enhance daily life.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.
  • To the affected part, apply warm compresses to get a temporary relief.
  • Rinse your eye carefully with clean water and try to blow any dust particle that could have entered.
  • Take over the counter medication to lubricate your eye or if there is pain due to allergy to soothe the eye.
  • If there is persistent pain in your eye, consult your doctor and follow the medication immediately.

Directions for Use

  • Nor-Metrogyl O Suspension can be administered with or without food as directed by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Administer the prescribed dose to the child using the measuring cup/dosing syringe.
  • Shake well before use.

How Nor-Metrogyl O Suspension Works

Nor-Metrogyl O Suspension is a combination medicine containing Ofloxacin (fluoroquinolone) and Metronidazole (antimicrobials). Ofloxacin works by inhibiting the repair of the bacterial cell wall (a protective covering) and causing damage to the bacterial cell wall. This eventually leads to the death of the bacterial cell and thus prevents the growth of bacterial infections. Metronidazole kills parasites and anaerobic bacteria that are responsible for causing infections. It works by damaging their DNA.
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Alcohol

Not applicable

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Pregnancy

Not applicable

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Breast Feeding

Not applicable

-

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Driving

Not applicable

-

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Liver

Caution

Please consult your doctor if your child has a liver impairment or if you have any concerns regarding this.

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Kidney

Caution

Please consult your doctor if your child has a kidney impairment or if you have any concerns regarding this.

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Children

Safe if prescribed

Nor-Metrogyl O Suspension is safe for children if prescribed by the doctor. The dose of the medicine will be decided by your paediatrician. Do not give more than the recommended dose to your child.

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Heart

Caution

Nor-Metrogyl O Suspension may rarely cause a serious heart rhythm issue (QT prolongation and torsades de pointes). Children with heart conditions or on certain medications may be at higher risk. Consult a pediatrician before use.

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Geriatrics

Not applicable

Nor-Metrogyl O Suspension is for paediatric patients only.

What if I have taken an overdose of Nor-Metrogyl O Suspension

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Nor-Metrogyl O Suspension may include confusion, dizziness or drowsiness, hot and cold flushes, loss of muscle coordination, nausea, numbness and swelling of the face, numbness, pain, burning, or tingling in your hands or feet, seizures, slurred speech, and vomiting. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Diet & Lifestyle Advise

  • Include more fiber-enriched food in your child’s diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth.
  • Fiber foods may help restore healthy gut bacteria after a course of antibiotics.
  • Avoid giving too much calcium, or iron-enriched foods, as it might affect the working of Nor-Metrogyl O Suspension. 
  • Make your child drink more fluids to avoid dehydration.
  • Do not make your child drink or eat a lot of caffeine-containing products such as cola, or chocolate.
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Have a query?

How Soon It Starts Working

The time required for Nor-Metrogyl O Suspension to start to work: The onset time of Nor-Metrogyl O Suspension has not been clinically established. The time for which the effects of Nor-Metrogyl O Suspension last: The duration of Nor-Metrogyl O Suspension’s effect is clinically not established.

What if you forget to take Nor-Metrogyl O Suspension

If you miss administering a dose to your child, give it as soon as you remember. If it's almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not give two doses at once.

Storage

• Store in a cool and dry place away from sunlight. • Keep Nor-Metrogyl O Suspension out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

Avoid giving Nor-Metrogyl O Suspension to your child if she/he is allergic to antibiotics. Keep your doctor informed about your child’s health condition including his current medications and medical history to rule out any side effects/interactions. Before administration, let your paediatrician know if your child has lung disease, muscle weakness, liver, and kidney disease. Dairy products should be avoided along with Nor-Metrogyl O Suspension.

Drug-Drug Interactions

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Drug-Drug Interactions: Nor-Metrogyl O Suspension may interact with caffeine-containing medications, antacids, etc. Give Nor-Metrogyl O Suspension either 2 hours before or 2 hours after taking an antacid, multivitamin, or other product that has calcium/magnesium/aluminium/iron/zinc,

Drug-Food Interactions: No interactions found/established. 

Drug-Disease Interactions: Inform your doctor before administering Nor-Metrogyl O Suspension if your child has any history of lung disease, kidney or liver disease.

Ofloxacin + MetronidazoleAmprenavir
Critical
Ofloxacin + MetronidazoleCisapride
Critical

Drug-Drug Interactions

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Ofloxacin + MetronidazoleAmprenavir
Critical
How does the drug interact with Nor-Metrogyl O Suspension 60ml:
Co-administration of Amprenavir with Ofloxacin and Metronidazole can increase the risk or severity of side effects.

How to manage the interaction:
Taking Ofloxacin and Metronidazole with Amprenavir is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience throbbing in the head and neck, difficulty breathing, vomiting, chest pain, rapid heartbeat, palpitation, low blood pressure, dizziness contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Ofloxacin + MetronidazoleCisapride
Critical
How does the drug interact with Nor-Metrogyl O Suspension 60ml:
Coadministration of Ofloxacin and Metronidazole with Cisapride can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Ofloxacin Metronidazole with Cisapride together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience dizziness, shortness of breath, chest pain, rapid heartbeat contact a doctor immediately. Do not discontinue any medications without consulting a doctor. Note: Cisapride is no longer available on the market.
Ofloxacin + MetronidazoleHalofantrine
Critical
How does the drug interact with Nor-Metrogyl O Suspension 60ml:
Using halofantrine together with ofloxacin and Metronidazole can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Ofloxacin and Metronidazole with Halofantrine can cause an interaction, please consult a doctor before taking it. You should seek immediate medical attention if you develop dizziness, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
Ofloxacin + MetronidazoleAmiodarone
Critical
How does the drug interact with Nor-Metrogyl O Suspension 60ml:
Taking Amiodarone with Ofloxacin and Metronidazole may significantly increase the risk of an abnormal heart rhythm.

How to manage the interaction:
Although Amiodarone with Ofloxacin and Metronidazole interact, it can be taken if prescribed by a doctor. If you get dizziness, or fast or racing heartbeats, consult a doctor. Do not stop taking any medications without consulting a doctor.
Ofloxacin + MetronidazoleArsenic trioxide
Severe
How does the drug interact with Nor-Metrogyl O Suspension 60ml:
Coadministration of Arsenic trioxide with ofloxacin and Metronidazole may raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Although Ofloxacin and Metronidazole with Arsenic trioxide interact, they can be used if prescribed by a doctor. Consult a doctor if you have dizziness, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
Ofloxacin + MetronidazoleTolazamide
Severe
How does the drug interact with Nor-Metrogyl O Suspension 60ml:
Co-administration of Ofloxacin and Metronidazole with Tolazamide can have an effect on blood glucose levels.

How to manage the interaction:
Although combining Ofloxacin and Metronidazole with Tolazamide can lead to an interaction, they can be taken on a doctor's advice. If you experience headache, dizziness, rapid heartbeat, increased thirst, and urination consult a doctor. Do not discontinue any medications without consulting a doctor.
Ofloxacin + MetronidazoleRibociclib
Severe
How does the drug interact with Nor-Metrogyl O Suspension 60ml:
Coadministration of Ribociclib together with ofloxacin and Metronidazole may raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Although Ofloxacin and Metronidazole with Ribociclib interact, they can be used if prescribed by a doctor. Consult a doctor if you have dizziness, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
Ofloxacin + MetronidazoleDroperidol
Severe
How does the drug interact with Nor-Metrogyl O Suspension 60ml:
Coadministration of Droperidol together with Ofloxacin and Metronidazole may increase the risk of an abnormal heart rhythm.

How to manage the interaction:
Although Ofloxacin and Metronidazole with Droperidol interact, they can be used if prescribed by a doctor. Consult a doctor if you have dizziness, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
Ofloxacin + MetronidazoleTolbutamide
Severe
How does the drug interact with Nor-Metrogyl O Suspension 60ml:
Co-administration of Ofloxacin and Metronidazole with Tolbutamide can affect blood glucose levels.

How to manage the interaction:
Although Ofloxacin and Metronidazole with Tolbutamide can lead to an interaction, they can be taken on a doctor's advice. If you experience headache, dizziness, rapid heartbeat, increased thirst, and urination consult a doctor. Do not discontinue any medications without consulting a doctor.
Ofloxacin + MetronidazoleTriamcinolone
Severe
How does the drug interact with Nor-Metrogyl O Suspension 60ml:
Co-administration of Triamcinolone with Ofloxacin and Metronidazole can cause tendinitis (inflammation of the thick fibrous cords that connect muscle to bone) and tendon rupture (injuries to the soft tissues that connect muscles and joints).

How to manage the interaction:
Although Ofloxacin and Metronidazole with Triamcinolone interact, they can be used if prescribed by a doctor. Consult a doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Nor-Metrogyl O Suspension is used to treat Bacterial Infections and Amoebic dysentry.
Nor-Metrogyl O Suspension is a combination medicine containing Ofloxacin (fluoroquinolone) and Metronidazole. Ofloxacin works by inhibiting the repair of the bacterial cell wall (a protective covering) and causing damage to the bacterial cell wall. This e Metronidazole kills parasites and anaerobic bacteria that are responsible for causing infections. It works by damaging their DNA.
No. As it is an antibiotic, it is advised to complete the entire treatment course of your child as prescribed. If the treatment is stopped abruptly, there may be drug resistance.
Nor-Metrogyl O Suspension can cause diarrhea in children. Nor-Metrogyl O Suspension is an antibiotic that kills toxic bacteria, but it can also affect the useful bacteria in your intestine or stomach and lead to diarrhea. If your child experience diarrhea that is watery or bloody, call your doctor. Do not use anti-diarrheal medicine unless your paediatrician suggests it.
Let the doctor know if the child has liver problems, blood issues, a low white blood cell count (leukopenia), or nervous system conditions (such as convulsions). Taking Nor-Metrogyl O Suspension may also increase the risk of developing tendinitis (swelling of the tissue that connects bone to muscle) or tendon rupture. Dairy products should be avoided while using Nor-Metrogyl O Suspension, and you should limit exposure to sunlight, as it may increase the risk of phototoxicity or photosensitivity.
Nor-Metrogyl O Suspension can be useful in treating loose motions if the cause is a bacterial or parasitic infection. However, it is not recommended for all cases of diarrhoea, as it may not be effective for viral infections or non-infectious causes. Please consult your doctor for proper diagnosis and treatment.
If your child develops a rash after taking Nor-Metrogyl O Suspension, it could be a sign of an allergic reaction or a side effect. Discontinue the medication right away and contact your doctor to discuss what to do next and get the right treatment.
Yes, Nor-Metrogyl O Suspension is an antibiotic that combines two medicines: ofloxacin and metronidazole. Ofloxacin targets bacterial DNA replication, while metronidazole is effective against anaerobic bacteria and certain parasites. Both are bactericidal in nature, and collectively they help treat the infection effectively.
If you accidentally give an excess dose of Nor-Metrogyl O Suspension, monitor for potential side effects such as nausea, vomiting, stomach upset, loss of appetite, dry mouth, and a metallic taste. Contact your doctor immediately, as taking too much of the antibiotic may lead to adverse reactions.
If your child shows no improvement even after completing the prescribed course of Nor-Metrogyl O Suspension, please consult your doctor. Also, inform the doctor if the symptoms are getting worse while using Nor-Metrogyl O Suspension.
To prevent any interactions, it is advised to consult the doctor before using other medicines with Nor-Metrogyl O Suspension. Inform the doctor if the child is taking anti-arrhythmics (quinidine, hydroquinidine, disopyramide, amiodarone, sotalol, dofetilide, ibutilide), tricyclic antidepressants, (clomipramine, amitriptyline), antipsychotics, or antimicrobials (erythromycin, clarithromycin, azithromycin).
Though Nor-Metrogyl O Suspension may not interact with vaccines, it is advised to consult the doctor before receiving vaccination. Let the doctor know if your child is due to undergo vaccination while on treatment with Nor-Metrogyl O Suspension.
Before giving Nor-Metrogyl O Suspension to your child, tell the doctor if your child has any allergies, especially to any of its ingredients, or to other antibacterial or anti-amoebic medicines. You should inform the doctor if your child has any existing medical conditions, such as liver or kidney problems, low white blood cell count (leukopenia), or muscle spasms (convulsions). Also, let the doctor know if your child is taking any other medications to prevent potential interactions.
Nor-Metrogyl O Suspension contains metronidazole which might cause reddish-brown discolouration of urine as a side effect. It is usually harmless, and the condition will subside once treatment is completed. However, consult the doctor if you have any concerns or notice dark urine or blood in urine.
It is best to consult your doctor before giving Nor-Metrogyl O Suspension along with cough & cold medicines. Nor-Metrogyl O Suspension is typically used to treat bacterial infections, but it does not work against viral infections like the common cold.
The common side effects of Nor-Metrogyl O Suspension include nausea, vomiting, stomach pain, headache, and dizziness. If these side effects persist or worsen, please consult your doctor.
If you forget to give Nor-Metrogyl O Suspension to your child, give the missed dose as soon as you remember, unless it is almost time for the next dose. If that is the case, skip the missed dose and give the next dose at the usual time. Never give two doses at once to make up for a missed dose.
Yes, Nor-Metrogyl O Suspension is a broad-spectrum antibiotic that can treat a variety of infections in different parts of the body. It is effective against infections in areas such as the gastrointestinal tract, lungs, blood, heart, skin, bones, joints, and nervous system.

Disclaimer

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Reference

  1. Ofloxacin [FDA Label]. 2008. [Accessed on 19 Jan. 2021]Check here
  2. Metronidazole Rosemont 200mg/5ml Oral Suspension - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2022 [Accessed on 08 Dec 2025]Check here
  3. Metronidazole Rosemont 200mg/5ml Oral Suspension - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2022 [Accessed on 08 Dec 2025]Check here
  4. Ofloxacin 200 mg Tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2022 [Accessed on 08 Dec 2025]Check here
  5. Ofloxacin 200 mg Tablets - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2022 [Accessed on 08 Dec 2025]Check here
  6. Connor B. Weir; Jacqueline K. Le., Metronidazole, National Library of Medicine. [Revised April 2022] [Accessed on 22 June 2022]Check here
  7. JB Chemicals, OFM SUSP, CIMS. [Accessed on 22 June 2022] suspCheck here

Country of origin

India

Manufacturer/Marketer address

SHETH GOVINDRAO SMRITI 83 B&CDR A B ROAD WORLI MUMBAI MH 400018 INDIA
Other Info - NOR0392
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