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compositionComposition:CEFAZOLIN-2000MG
prescription
Prescription Medicine
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Nostof 2 gm Injection 1's is used to treat bacterial infections. It contains Cefazolin which works by interfering with the formation of bacterial cell walls, thereby killing the bacteria. In some cases, this medicine may cause side effects such as injection site reactions (pain, swelling, redness), vomiting, nausea, indigestion, diarrhoea, and dizziness. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CEFAZOLIN-2000MG

Manufacturer/Marketer :

Jolly Healthcare

Consume Type :

Parenteral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Nostof 2 gm Injection 1's

Nostof 2 gm Injection 1's is a prescription antibiotic injection used to treat a wide variety of serious bacterial infections. It is commonly prescribed for infections of the skin, bones, joints, lungs, and urinary tract, as well as for preventing infections before and after surgical procedures.

Because this medicine is given as an injection, it enters your bloodstream directly, meaning food intake does not affect how well it works. To fight your infection effectively, it must be given at regular, consistent intervals as directed by your doctor. Staying well-hydrated and resting during your treatment will support your body's natural healing process.

While using Nostof 2 gm Injection 1's, you may experience mild side effects such as redness or discomfort at the injection site, mild nausea, or temporary stomach upset. If you experience severe symptoms like persistent watery diarrhoea, severe abdominal cramps, or a high fever, you must contact your doctor immediately.

Before starting treatment, tell your doctor if you have kidney disease, stomach disorders like colitis, or a history of allergies. Do not take this if you have ever had a severe allergic reaction to cephalosporin antibiotics or penicillin.

This medication can interact with other drugs such as blood thinners or certain water pills, which may increase the risk of side effects. If you are pregnant, breastfeeding, or an elderly patient, talk to your doctor to ensure this treatment is safe for your specific needs.

Uses of Nostof 2 gm Injection 1's

Nostof 2 gm Injection 1's is used to treat various bacterial infections and may also be given to help prevent infections associated with certain surgical procedures. Its uses include:

  • Surgical infection prevention: Nostof 2 gm Injection 1's is injected before, during, or after surgery to prevent bacteria from entering and infecting the surgical site.
  • Skin and soft tissue infections: Nostof 2 gm Injection 1's helps clear painful bacterial skin infections by stopping the growth of the bacteria causing the swelling, heat, and redness.
  • Bone and joint infections: Nostof 2 gm Injection 1's penetrates deep into bone and joint tissues to eliminate stubborn bacteria, aiding in recovery and reducing painful inflammation.
  • Urinary tract infections (UTIs): Nostof 2 gm Injection 1's treats severe or complicated infections of the bladder and kidneys by targeting the specific bacteria in the urinary tract.
  • Severe lung infections: Nostof 2 gm Injection 1's helps resolve serious respiratory infections, such as pneumonia, by clearing bacterial pathogens from the lungs.
  • Blood infections (sepsis): Nostof 2 gm Injection 1's works quickly in the bloodstream to fight off widespread, life-threatening bacterial infections throughout the body.

Key Benefits

Nostof 2 gm Injection 1's is a cephalosporin antibiotic that helps treat susceptible bacterial infections and may also provide protection against certain surgery-related infections. Its benefits include:

  • Fast-acting relief: Because Nostof 2 gm Injection 1's is injected directly into a vein or muscle, it enters the bloodstream immediately. This allows the medicine to start fighting the infection much faster than oral antibiotics, helping you feel better sooner.
  • Effective infection clearance: It helps relieve debilitating symptoms like high fever, severe pain, and weakness by systematically destroying the bacteria causing the illness, putting you on the path to a steady recovery.
  • Crucial surgical protection: For patients undergoing surgery, it provides a vital shield against potential post-operative infections, ensuring a smoother, safer, and less complicated healing process.
Side effects of Nostof 2 gm Injection
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Nostof 2 gm Injection 1's will be administered by a nurse or doctor.
  • Do not self-administer

How Nostof 2 gm Injection 1's Works

Nostof 2 gm Injection 1's contains cefazolin, which belongs to a class of medicines called cephalosporin antibiotics. It works by targeting the protective outer wall that bacteria need to survive. Bacteria require a strong cell wall to maintain their shape and protect themselves from their environment. Nostof 2 gm Injection 1's prevents the bacteria from properly building and repairing this wall. Without a stable outer wall, the bacterial cells rupture and die. This effectively stops the infection from spreading further, allowing your body's natural immune system to clear out the remaining bacteria.
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Alcohol

Unsafe

Avoid consuming alcohol while taking Nostof 2 gm Injection 1's to prevent unpleasant side-effects.

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Pregnancy

Caution

Nostof 2 gm Injection 1's is a category B pregnancy drug and is given to pregnant women only if the doctor thinks benefits outweigh risks. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Caution

Nostof 2 gm Injection 1's may be excreted in human milk in small amounts. Therefore, it is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks. Please consult a doctor if you are breastfeeding.

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Driving

Caution

Nostof 2 gm Injection 1's may cause dizziness in some people. Therefore, avoid driving if you feel dizzy after taking Nostof 2 gm Injection 1's.

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Liver

Caution

Take Nostof 2 gm Injection 1's with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Nostof 2 gm Injection 1's should be used in patients with kidney diseases with extreme caution as Nostof 2 gm Injection 1's may cause renal toxicity. Dose adjustments are necessary.

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Children

Safe if prescribed

Nostof 2 gm Injection 1's is safe for children if prescribed by a doctor. Do not use Nostof 2 gm Injection 1's in a child without a doctor's advice. Nostof 2 gm Injection 1's should never be used in a premature baby, or in any new-born baby who has jaundice (yellowing of the skin or eyes).

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Heart

Consult your doctor

Please inform your doctor if you have a history of heart disease before using Nostof 2 gm Injection 1's. Your doctor will prescribe it only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Limited information available for use of Nostof 2 gm Injection 1's in elderly patients. Please consult your doctor.

What if I have taken an overdose of Nostof 2 gm Injection 1's

If you suspect an overdose, or if you experience severe symptoms like seizures, extreme dizziness, or difficulty breathing after receiving too much of this medicine, seek immediate medical attention or call emergency services right away.

Diet & Lifestyle Advise

  • Stay well-hydrated: Drink plenty of water throughout the day. Good hydration helps your kidneys flush out the medication efficiently and keeps your body strong while fighting infection.
  • Support your gut health: Antibiotics can disrupt the balance of healthy bacteria in your stomach. Consider eating probiotic-rich foods like plain yoghurt or taking a probiotic supplement a few hours after your injection to help prevent stomach upset.
  • Get plenty of rest: Your body uses a large amount of energy to fight off infections. Prioritise sleep and limit strenuous physical activities until you have fully recovered.
  • Avoid alcohol: While alcohol does not directly stop Nostof 2 gm Injection 1's from working, it can strain your liver, cause dehydration, and worsen side effects like nausea or dizziness, delaying your recovery.
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How Soon It Starts Working

The time required for Nostof 2 gm Injection 1's to start to work: Nostof 2 gm Injection 1's starts to show its action within 15 to 60 minutes of administration. The time for which the effects of Nostof 2 gm Injection 1's last: Nostof 2 gm Injection 1's effect lasts for 6 to 8 hours.

What if you forget to take Nostof 2 gm Injection 1's

If you are injecting this medicine at home and you miss a dose, inject it as soon as you remember. However, if it is almost time for your next scheduled injection, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for a missed one. If you are unsure, talk to your doctor or pharmacist for guidance.

Storage

•Store the dry powder vials of Nostof 2 gm Injection 1's at room temperature, between 20°C and 25°C (68°F to 77°F) • Keep them in their original packaging to protect them from direct light and moisture.

Drug Warnings

  • Inspect before use: Always check the liquid vial before injecting. The solution must be clear and colourless to pale yellow. Do not use it if you notice any cloudiness, discolouration, or floating particles.
  • Rotate injection sites: If you are receiving muscle injections, rotate the injection site each time (such as using different thighs or buttocks) to minimise skin irritation and muscle soreness.
  • Practice needle safety: Never reuse needles or syringes. Dispose of them immediately after a single use in a designated sharps container to prevent accidental needle sticks.
  • Complete the full course: Even if you feel completely better after a few days, finish the entire course prescribed by your doctor. Stopping too early can allow the remaining bacteria to multiply and become resistant to the medication.
  • Monitor your kidneys: If you are on this medicine for a prolonged period, your doctor may require routine blood tests to check your kidney function.

Drug-Drug Interactions

verifiedApollotooltip

Certain medicines may interact with Nostof 2 gm Injection 1's and increase the risk of bleeding, kidney-related complications, or reduced vaccine effectiveness. Important interactions include:

  • Blood thinners (like warfarin): Injecting Nostof 2 gm Injection 1's with blood thinners may increase the risk of bleeding. Your doctor may need to monitor your blood clotting times closely.
  • Water pills (loop diuretics like furosemide): Combining these with Nostof 2 gm Injection 1's can increase the risk of kidney damage.
  • Live bacterial vaccines (such as typhoid vaccine): This medicine can stop live bacterial vaccines from working properly. Avoid getting vaccinations while using this medicine unless approved by your doctor.
CefazolinRifampicin
Severe
CefazolinHeparin
Severe

Drug-Drug Interactions

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CefazolinRifampicin
Severe
How does the drug interact with Nostof 2 gm Injection:
Taking rifampicin with Nostof 2 gm Injection may increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between Nostof 2 gm Injection and rifampicin, they can be taken together if prescribed by a doctor. However, if you experience unusual bleeding, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
CefazolinHeparin
Severe
How does the drug interact with Nostof 2 gm Injection:
When Nostof 2 gm Injection is used with Heparin, it enhances the effects of heparin.

How to manage the interaction:
Although taking Heparin and Nostof 2 gm Injection together can cause an interaction, it can be taken if a doctor has suggested it. However, consult the doctor if you experience bleeding, bruising, throwing up, headache, feeling lightheaded, feeling weak, or blood in your urine or stools. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Nostof 2 gm Injection 1's when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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FAQs

Nostof 2 gm Injection 1's is used to treat bacterial infections of the nose, lungs, ear, bones, joints, skin, urinary tract, prostate gland and reproductive system. Besides this, it is also used before surgeries to prevent post-surgical bacterial infections.
Nostof 2 gm Injection 1's contains Cefazolin which works by interfering with the formation of bacterial cell walls, thereby impairing the bonds that hold the bacterial cell wall together. This process ultimately disrupts the formation of bacterial cell wall formation, which kills the bacteria. Thus, it helps in treating and preventing the spread of infections.
Diarrhoea might be a side-effect of Nostof 2 gm Injection 1's. Drink lots of fluids and eat food rich in fibre if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience excess diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.
It is recommended to complete the course of Nostof 2 gm Injection 1's even if you feel better as it is an antibiotic, and leaving it in between may lead to even severe infection that will, in fact, stop responding to the antibiotic as well (antibiotic resistance).
Nostof 2 gm Injection 1's may interfere with urine test (for sugar) and Coomb’s test (blood test) giving false-positive results. Therefore, if you are about to undergo any laboratory tests, inform your doctor or lab technician that you are taking Nostof 2 gm Injection 1's.
Nostof 2 gm Injection 1's should be used with caution in patients with kidney problems as it may increase the risk of adverse effects. Therefore, inform your doctor if you have any kidney problems before taking Nostof 2 gm Injection 1's so that the dose may be adjusted accordingly.
Consult the doctor if your condition does not get better even after completing the duration of treatment or if your condition worsens during treatment with Nostof 2 gm Injection 1's.
In some cases, Nostof 2 gm Injection 1's may cause side effects like injection site reactions (pain, swelling, redness), vomiting, allergic reaction, nausea, indigestion, diarrhoea, lightheadedness and dizziness. Most of these side effects of Nostof 2 gm Injection 1's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
No, Nostof 2 gm Injection 1's is not absorbed well by the stomach, so it is not available as a pill or tablet. It must be injected directly into a vein or a muscle to work effectively. Talk to your doctor if you have concerns about receiving injections.
This medicine is generally considered safe during pregnancy, but it should only be used if clearly needed and prescribed by a healthcare provider. If you are pregnant or planning to become pregnant, talk to your doctor to weigh the benefits and risks.
It is best to avoid alcohol during your treatment. Alcohol does not stop the medicine from working, but it can dehydrate you, strain your liver, and worsen side effects like nausea, headache, or dizziness. Talk to your doctor for personalised advice.
Mild pain, redness, or swelling at the injection site is common. Applying a warm compress can sometimes help ease the discomfort. However, if the pain worsens or if you notice spreading redness, heat, or pus, talk to your doctor right away.
Yes, there is a small chance of cross-reactivity. If you have had a severe allergic reaction to penicillin, you must inform your doctor before using this medicine, as you may also be allergic to it. Talk to your doctor to discuss safe alternatives.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Cc-102, Link Road, Jawahar Nagar, Jaipur -302004(Raj) India
Other Info - NOS0135
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