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Ntinib 200 Capsule 30's is used to treat Philadelphia chromosome-positive chronic myeloid leukaemia (a type of blood cancer). It contains Nilotinib, which works by blocking the action of an abnormal protein produced by an abnormal Philadelphia chromosome that signals abnormal white blood cells (cancerous cells) to multiply. Thus, it stops the multiplication, inhibits the growth of cancerous cells, and then causes their death.
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About Ntinib 200 Capsule 30's
Ntinib 200 Capsule 30's belongs to the class of anticancer drugs called tyrosine kinase inhibitors used in the treatment of Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML). Ph+ CML is a type of blood cancer that causes white blood cells to behave differently.
Ntinib 200 Capsule 30's contains Nilotinib which works by blocking the action of an abnormal protein (Bcr-Abl tyrosine kinase) produced by an abnormal Philadelphia chromosome that signals abnormal white blood cells (cancerous cells) to multiply. Thereby, it stops the multiplication and inhibits the growth of cancerous cells and then causes the death of these cells.
Take Ntinib 200 Capsule 30's as prescribed. You are recommended to take Ntinib 200 Capsule 30's for as long as your doctor has advised it for you based on your medical condition. Sometimes, Ntinib 200 Capsule 30's may cause common side effects such as vomiting, nausea, diarrhoea, headache, constipation, tiredness, and muscle and joint pain. Most of these side effects of Ntinib 200 Capsule 30's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
If you are allergic to Nilotinib or any other medicines, please tell your doctor. Avoid taking Ntinib 200 Capsule 30's if you are pregnant or breastfeeding. You are recommended to use effective contraceptive methods while taking Ntinib 200 Capsule 30's and for two weeks after completing the course of Ntinib 200 Capsule 30's. Ntinib 200 Capsule 30's is not recommended for children below one year of age. Drive only if you are alert as Ntinib 200 Capsule 30's may cause dizziness or visual disorders as side effects in some people. If you have yellow skin and eyes, dark-coloured urine, or stomach pain while taking Ntinib 200 Capsule 30's, contact your doctor immediately, as these might be symptoms of liver problems.
Uses of Ntinib 200 Capsule 30's
Ntinib 200 Capsule 30's is used in the treatment of Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML). The detailed uses of Ntinib 200 Capsule 30's are as follows:

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Directions for Use
Medicinal Benefits
Ntinib 200 Capsule 30's contains Nilotinib, an anticancer drug used to treat Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML). In chronic myeloid leukemia (CML) patients, a change in genetic material (DNA) triggers a signal that tells the body to produce more abnormal white blood cells (cancerous cells). Nilotinib works by blocking this signal and thus stops the production of cancerous cells. Ntinib 200 Capsule 30's is used in adults and children with newly diagnosed Ph+ CML in the chronic phase and in adults with Ph+ CML in the accelerated and chronic phase who did not tolerate or no longer benefit from other treatments, including Imatinib.
How Ntinib 200 Capsule 30's Works
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What if I have taken an overdose of Ntinib 200 Capsule 30's
Drug Warnings
If you are allergic to Nilotinib or any other medicines, please tell your doctor. Avoid taking Ntinib 200 Capsule 30's if you are pregnant or breastfeeding. You are recommended to use effective contraceptive methods while taking Ntinib 200 Capsule 30's and for two weeks after completing the course of Ntinib 200 Capsule 30's. Ntinib 200 Capsule 30's is not recommended for children below one year of age. Ntinib 200 Capsule 30's may affect the growth and development of children with chronic phase Ph+ CML. Some children and adolescents may have slower than normal growth while taking Ntinib 200 Capsule 30's. Therefore, your doctor will monitor the growth of your child at regular visits. Drive only if you are alert as Ntinib 200 Capsule 30's may cause dizziness or visual disorders as side effects in some people. Ntinib 200 Capsule 30's may increase the risk of liver problems, especially in people with a history of liver problems. Therefore, if you have yellow skin and eyes, dark-coloured urine, or stomach pain while taking Ntinib 200 Capsule 30's, contact your doctor immediately, as these might be symptoms of liver problems. Inform your doctor if you have a severe problem with lactose (milk sugar) or other sugars as Ntinib 200 Capsule 30's may contain lactose. Most people who have mild or moderate lactose intolerance can take Ntinib 200 Capsule 30's. Avoid taking Ntinib 200 Capsule 30's if you have low levels of magnesium or potassium in the blood or long QTc syndrome. If you have had a surgical procedure involving the removal of the entire stomach (total gastrectomy), inform your doctor before taking Ntinib 200 Capsule 30's.
Diet & Lifestyle Advise
Habit Forming
Therapeutic Class
Alcohol
Consult your doctor
The interaction of Ntinib 200 Capsule 30's with alcohol is unknown. Please discuss with your doctor if you have any concerns regarding this.
Pregnancy
Unsafe
Ntinib 200 Capsule 30's is not recommended for use during pregnancy as it may harm the unborn baby. Therefore, inform your doctor if you are pregnant or planning for pregnancy before taking Ntinib 200 Capsule 30's. Also, you are advised to use effective birth control measures during treatment with Ntinib 200 Capsule 30's and for up to 2 weeks after the last dose of Ntinib 200 Capsule 30's.
Breast Feeding
Unsafe
You are recommended to avoid breastfeeding during treatment with Ntinib 200 Capsule 30's and for two weeks after the final dose. Inform your doctor if you are breastfeeding.
Driving
Caution
If you experience side effects such as dizziness or visual disorders, avoid driving or operating machinery until you are alert.
Liver
Caution
Inform your doctor if you have liver problems before taking Ntinib 200 Capsule 30's. Your doctor may adjust the dose if necessary based on your condition.
Kidney
Consult your doctor
Limited information is available on the use of Ntinib 200 Capsule 30's in patients with impaired kidney function. Therefore, if you have kidney problems, inform your doctor before taking Ntinib 200 Capsule 30's.
Children
Caution
Ntinib 200 Capsule 30's is not recommended for children below 1 year of age as the safety and effectiveness were not established.
Heart
Please consult your doctor if you have heart problems before using Ntinib 200 Capsule 30's.
Geriatrics
Consult your doctor
Please consult a doctor if you have any concerns regarding the use of Ntinib 200 Capsule 30's in elderly patients.
Ntinib 200 Capsule 30's is used to treat Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML).
Ntinib 200 Capsule 30's contains Nilotinib, an anticancer drug. In chronic myeloid leukemia (CML) patients, a change in genetic material (DNA) triggers a signal that tells the body to produce more abnormal white blood cells (cancerous cells). Nilotinib works by blocking this signal and thus stops the production of cancerous cells.
You are not recommended to take antacids and Ntinib 200 Capsule 30's at the same time. You are advised to take antacids containing magnesium hydroxide, aluminium hydroxide, and simethicone about two hours before or two hours after taking Ntinib 200 Capsule 30's. However, please consult a doctor before taking other medicines with Ntinib 200 Capsule 30's.
You are recommended to avoid grapefruit juice, grapefruit and any supplement containing grapefruit extract while taking Ntinib 200 Capsule 30's as it may increase the amount of Nilotinib in the body and cause serious side effects.
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