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compositionComposition:RUCAPARIB-300MG
prescriptionPrescription Medicine
Nuparp 300 Tablet 60's

Nuparp 300 Tablet is indicated in the treatment of ovarian, fallopian tube, and primary peritoneal cancer. It contains Rucaparib, which works by blocking an enzyme that repairs damaged DNA in cancer cells, resulting in their death. Thus, it kills cancer cells and helps treat cancer. In some cases, it may cause side effects such as fatigue, nausea, vomiting, diarrhoea, and decreased or loss of appetite.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

RUCAPARIB-300MG

Manufacturer/Marketer :

Zydus Cadila

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Nuparp 300 Tablet

Nuparp 300 Tablet belongs to the group of anti-cancer medicines called PARP (poly adenosine diphosphate-ribose polymerase) indicated in the treatment of ovarian cancer, fallopian tube, and primary peritoneal cancer. It is also indicated in the treatment of prostate cancer that has spread to other areas in the body in people with a specific gene who have received other treatments.

Nuparp 300 Tablet contains Rucaparib, which works by blocking an enzyme that repairs damaged DNA in cancer cells, resulting in their death. Thereby, it kills cancer cells and helps treat cancer.

In some cases, Nuparp 300 Tablet may cause side effects such as fatigue, nausea, vomiting, diarrhoea, decreased or loss of appetite. Most of these side effects may not require medical attention and resolve gradually over time. However, if any of the side effects persist or worsen, inform your doctor.

Let the doctor know if you are allergic to any of the components in Nuparp 300 Tablet . Nuparp 300 Tablet is not recommended for use in children as the safety and effectiveness have not been established. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Nuparp 300 Tablet

Nuparp 300 Tablet used in the treatment of ovarian cancer, fallopian tube cancer, primary peritoneal cancer and prostate cancer. The detailed uses of Nuparp 300 Tablet are as follows:

  • Treatment of Ovarian Cancer: Nuparp 300 Tablet targets and treats ovarian cancer, particularly in patients with BRCA mutations, by inhibiting PARP enzymes and blocking cancer cell growth.
  • Managing Fallopian Tube Cancer: Nuparp 300 Tablet provides treatment options for patients with fallopian tube cancer, offering a potential therapeutic benefit in managing the disease.
  • Therapy for Primary Peritoneal Cancer: Nuparp 300 Tablet is effective in treating primary peritoneal cancer, helping to control tumor growth and improve patient outcomes.
  • Treatment of Prostate Cancer: Nuparp 300 Tablet is used to treat certain cases of prostate cancer, especially those with specific genetic mutations, such as BRCA1 and BRCA2, providing a targeted treatment approach.

Key Benefits

Nuparp 300 Tablet belongs to the group of anti-cancer medicines called PARP (poly adenosine diphosphate-ribose polymerase) indicated in the treatment of prostate cancer. It is also used to help maintain the response to other treatments for certain types of ovarian cancer, fallopian tube, and primary peritoneal cancer that have returned in adults who have partially or completely responded to other chemotherapy treatments and in people with a specific gene who have received treatment with at least two other chemotherapy treatments. Nuparp 300 Tablet contains Rucaparib, which works by blocking an enzyme that repairs damaged DNA in the cancer cells, resulting in their death. Thereby, it kills cancer cells and helps treat cancer. 

Side effects of Nuparp 300 Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Regularly brush and floss your teeth.
  • Rinse your mouth with water and baking soda a solution to neutralize acid in the mouth. This makes your food taste as it should.
  • Drink plenty of water or non-caffeinated drinks to prevent dry mouth which may lead to altered taste.
  • Try ginger, peppermint, fruit or green teas, lemonade, ginger ale or fruit juice to help mask unpleasant tastes.
  • Try sucking on sugar-free ice pops or ice cubes to prevent dry mouth.
  • High levels of liver enzymes need immediate medical attention.
  • Watch your diet and consume low-fat foods, like green leafy vegetables, fish, whole grains, nuts, etc.
  • Regularly do strengthening exercises to control your cholesterol levels.
  • Avoid drinking alcohol as it can affect your liver.
  • Focus on losing weight as it can help control cholesterol and maintain liver enzymes.
  • Practice yoga and meditation to improve liver functioning and overall health.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

Directions for Use

  • Nuparp 300 Tablet can be taken with or without food.
  • Follow your doctor’s instructions on the dosage and timing of this medication. Try to take it at the same time each day or as recommended by a doctor for optimal results.
  • Swallow the whole tablet with a glass of water.
  • Do not break, chew or crush Nuparp 300 Tablet .

How Nuparp 300 Tablet Works

Nuparp 300 Tablet contains Rucaparib, which works by blocking an enzyme that repairs damaged DNA in cancer cells, resulting in their death. Thereby, it kills cancer cells and helps treat cancer.
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Alcohol

Consult your doctor

It is not known whether Nuparp 300 Tablet interacts with alcohol. Please consult your doctor.

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Pregnancy

Unsafe

Nuparp 300 Tablet should not be used during pregnancy as it may harm your unborn baby.

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Breast Feeding

Unsafe

Avoid breastfeeding whilst on treatment with Nuparp 300 Tablet and for at least two weeks after the last dose.

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Driving

Caution

In some cases, Nuparp 300 Tablet may cause tiredness. So, drive or operate machinery only if you are alert.

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Liver

Consult your doctor

If you have a history of liver disease, please inform your doctor before taking Nuparp 300 Tablet .

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Kidney

Consult your doctor

If you have a history of kidney disease, please inform your doctor before taking Nuparp 300 Tablet .

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Children

Unsafe

Nuparp 300 Tablet is not recommended for children as the safety and effectiveness have not been established.

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Heart

Caution

Nuparp 300 Tablet may be used in patients with heart problems, but only with close monitoring due to potential cardiovascular side effects. Your doctor will assess your heart status and adjust treatment as needed.

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Geriatrics

Caution

Nuparp 300 Tablet is considered safe for elderly patients, but doctors monitor closely for side effects and organ function. No dose adjustment is typically needed unless other health issues are present.

What if I have taken an overdose of Nuparp 300 Tablet

Do not take more than prescribed dose. Using more medication will not improve your symptoms; rather they may cause poisoning or serious side-effects. If you suspect that you may have overdosed of Nuparp 300 Tablet , please go to the emergency department of the closest hospital or nursing home.

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain a proper weight.
  • Avoid smoking and alcohol consumption.
  • Include vegetables, fruits, herbs, and spices in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs, and added sugar.
  • Get optimal sleep; rest well.

Have a query?

Drug Warnings

Do not take Nuparp 300 Tablet if you are allergic to any of its components or if you are pregnant or breastfeeding. Nuparp 300 Tablet may cause serious side effects like bone marrow problems called Myelodysplastic Syndrome (MDS) or a type of cancer of the blood called Acute Myeloid Leukemia (AML). Seek immediate medical attention if you experience weakness, weight loss, fever, frequent infections, blood in urine or stools, feeling very tired, shortness of breath, and bleeding or bruising more easily. Consult your doctor immediately if you become pregnant during treatment with Nuparp 300 Tablet . Let your doctor know if you are taking any other medicines, including supplements and herbal products.

Drug-Drug Interactions

verifiedApollotooltip
RucaparibZiprasidone
Critical
RucaparibCladribine
Severe

Drug-Drug Interactions

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RucaparibZiprasidone
Critical
How does the drug interact with Nuparp 300 Tablet:
Coadministration of Nuparp 300 Tablet and Ziprasidone may increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Nuparp 300 Tablet with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
RucaparibCladribine
Severe
How does the drug interact with Nuparp 300 Tablet:
Taking Nuparp 300 Tablet with Cladribine can increase the risk of developing serious infections.

How to manage the interaction:
There may be a possibility of interaction between Cladribine and Nuparp 300 Tablet, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away. These symptoms include fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you urinate. Do not stop using any medications without a doctor's advice.
RucaparibPirfenidone
Severe
How does the drug interact with Nuparp 300 Tablet:
Taking Pirfenidone with Nuparp 300 Tablet can increase the risk or severity of its side effects such as liver disease or gastric problems.

How to manage the interaction:
Co-administration of Pirfenidone with Nuparp 300 Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately.
RucaparibInfliximab
Severe
How does the drug interact with Nuparp 300 Tablet:
When Nuparp 300 Tablet is taken with Infliximab, can lead to or increase the risk or severity of developing serious infections.

How to manage the interaction:
Co-administration of Infliximab with Nuparp 300 Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RucaparibMoxifloxacin
Severe
How does the drug interact with Nuparp 300 Tablet:
Using moxifloxacin together with Nuparp 300 Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Moxifloxacin and Nuparp 300 Tablet, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - like a fast or irregular heartbeat, severe or long-lasting diarrhea, vomiting, complications, sudden feeling dizzy or lightheaded, fainting, difficulty breathing, or feeling your heart beating fast - make sure to call your doctor right away. Do not stop using any medications without a doctor's advice.
RucaparibGatifloxacin
Severe
How does the drug interact with Nuparp 300 Tablet:
Taking Gatifloxacin with Nuparp 300 Tablet can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Gatifloxacin with Nuparp 300 Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RucaparibSotalol
Severe
How does the drug interact with Nuparp 300 Tablet:
Using sotalol together with Nuparp 300 Tablet can increase the risk or severity of irregular heart rhythms which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Although there is a possible interaction between Sotalol and Nuparp 300 Tablet, you can take these medicines together if prescribed by a doctor. If you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations consult a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[CHEMOTHERAPY]

FAQs

Nuparp 300 Tablet is used treat Ovarian cancer, Fallopian tube cancer, Primary peritoneal cancer and Prostate cancer.

Nuparp 300 Tablet works by blocking an enzyme that repairs damaged DNA in the cancer cells, resulting in their death. Thereby, it helps treat cancer.

Nuparp 300 Tablet may make your skin sensitive to sunlight. Therefore, avoid unnecessary or prolonged exposure to sunlight. Also, wear protective clothing and apply sunscreen.

If you experience nausea, vomiting, diarrhoea, or abdominal pain, consult your doctor, as these may be signs that Nuparp 300 Tablet is affecting your stomach or bowels.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads,Ahmedabad €“ 380015 Gujarat, India.
Other Info - NUP0077

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