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Oceva 10mg/ml Injection is used to treat eye diseases causing vision impairment, such as neovascular (wet) age-related macular degeneration, macular oedema following retinal vein occlusion, diabetic macular oedema, proliferative diabetic retinopathy, and choroidal neovascularization. It is also used to treat retinopathy of prematurity in babies born prematurely. Oceva 10mg/ml Injection contains Ranibizumab, a vascular endothelial growth factor A (VEGF-A) antagonist, which binds to VEGF-A (a protein which causes abnormal blood vessel growth and swelling, leading to vision impairment) present in the eyes, blocks its action and prevents abnormal growth and swelling. Thus, it helps stabilize and improve your vision.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

RANIBIZUMAB-10MG/ML

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

Parenteral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Oceva 10mg/ml Injection

Oceva 10mg/ml Injection is a prescription injection used to treat serious vision conditions caused by abnormal blood vessel growth in the back of the eye. It is commonly prescribed to treat conditions like wet age-related macular degeneration and diabetic eye damage. By targeting the root cause of fluid leakage in the retina, this medicine helps protect and preserve your sight.

This medication is injected directly into the eye by a specialist, usually once a month or as decided by your eye doctor. Since it is an injection, you do not need to worry about taking it with or without food. To help support your treatment results, it is highly recommended to eat a diet rich in eye-healthy nutrients and protect your eyes from bright sunlight.

While using Oceva 10mg/ml Injection, you may experience mild, temporary side effects like eye redness, irritation, or seeing small spots in your vision. However, if you experience severe eye pain, worsening redness, or sudden changes in your vision, you must contact your doctor immediately. These serious signs require prompt medical evaluation to protect your eye health.

Before starting treatment, tell your eye doctor if you have any pre-existing eye conditions, such as glaucoma or a history of eye inflammation. Do not use this medicine if you currently have an active eye infection or severe inflammation inside your eye. Sharing your complete medical history helps ensure your doctor can plan your treatment safely.

There are no known direct interactions between this eye injection and foods or alcohol, but you should still tell your doctor about all other eye drops or medicines you use. If you are pregnant, breastfeeding, or an older adult, consult your doctor to discuss the risks and benefits of using this medicine.

Uses of Oceva 10mg/ml Injection

Oceva 10mg/ml Injection is used to treat serious vision conditions caused by abnormal blood vessel growth in the back of the eye. The detailed uses of Oceva 10mg/ml Injection are as follows:

  • Wet age-related macular degeneration (AMD): Oceva 10mg/ml Injection helps stop the growth and leakage of abnormal blood vessels in the macula, which prevents severe central vision loss.
  • Diabetic macular oedema (DME): Oceva 10mg/ml Injection reduces fluid buildup and swelling in the retina caused by leaking blood vessels in people with diabetes.
  • Diabetic retinopathy: Oceva 10mg/ml Injection treats damage to the retinal blood vessels, lowering the risk of severe vision loss and bleeding inside the eye.
  • Macular oedema following retinal vein occlusion (RVO): Oceva 10mg/ml Injection helps clear fluid accumulation in the retina that occurs after a blockage in one of the eye's veins.
  • Myopic choroidal neovascularisation (mCNV): Oceva 10mg/ml Injection stops abnormal blood vessels from growing under the retina in individuals with extreme near-sightedness.

Key Benefits

Oceva 10mg/ml Injection helps treat certain retinal and eye conditions by reducing swelling and abnormal fluid build-up in the eye. By protecting the retina, it helps preserve vision and supports long-term eye health.

  • Helps Preserve Vision: By controlling the underlying retinal swelling, Oceva 10mg/ml Injection helps stabilise vision and may improve visual clarity in some patients, supporting daily activities such as reading, driving, and recognising faces.
  • Reduces Retinal Swelling and Fluid Build-Up: By decreasing fluid leakage and swelling in the retina, Oceva 10mg/ml Injection helps protect the delicate tissues responsible for clear vision.
  • Supports Long-Term Eye Health: Regular treatment helps reduce the risk of progressive vision loss associated with chronic retinal conditions and supports ongoing protection of visual function.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication, to improve effectiveness.
  • Oceva 10mg/ml Injection will be administered by a healthcare professional.
  • Do not self-administer it.

How Oceva 10mg/ml Injection Works

Oceva 10mg/ml Injection contains ranibizumab, which works by targeting and blocking a specific protein in the eye called vascular endothelial growth factor A (VEGF-A). In several eye diseases, the body produces too much of this protein, which signals abnormal, weak blood vessels to grow in the retina. These new blood vessels are fragile and easily leak fluid, blood, and proteins, leading to swelling and vision loss. When injected into the eye, the active medicine in Oceva 10mg/ml Injection binds directly to VEGF-A, preventing it from interacting with its receptors. This action stops the growth of abnormal blood vessels and prompts existing leaking vessels to close up and dry. As a result, swelling and fluid accumulation in the retina decrease, which helps preserve and clear your vision.
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Oceva 10mg/ml Injection. Please consult the doctor.

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Pregnancy

Caution

Oceva 10mg/ml Injection should not be used during pregnancy unless the benefits outweigh the risks. Consult the doctor if you are pregnant, think you may be pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

It is not known whether Oceva 10mg/ml Injection passes into breast milk. However, if you are breastfeeding, inform your doctor before receiving Oceva 10mg/ml Injection.

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Driving

Caution

Oceva 10mg/ml Injection may cause temporary vision blurring. Avoid driving or operating heavy machinery if you experience this.

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Liver

Caution

If you have a history of liver problems, inform the doctor before receiving Oceva 10mg/ml Injection.

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Kidney

Caution

Dose adjustment may not be needed in patients with renal impairment. However, if you have a history of kidney problems, inform the doctor before receiving Oceva 10mg/ml Injection.

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Children

Caution

Oceva 10mg/ml Injection is not recommended for children as the safety and effectiveness have not been established except for retinopathy of prematurity (ROP) in babies born prematurely. However, the safety profile in preterm infants has not been established beyond 2 years.

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Heart

Caution

Oceva 10mg/ml Injection can generally receive even if you have heart problems, but with careful medical oversight. Studies show that Oceva 10mg/ml Injection does not significantly increase the risk of heart attack, stroke, or death in patients with cardiovascular conditions. However, if you're at high risk or receiving frequent injections, your doctor may evaluate your heart health more closely before proceeding.

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Geriatrics

Consult your doctor

Oceva 10mg/ml Injection is generally not recommended for geriatric patients with certain health risks unless clearly indicated. Due to age-related vulnerabilities, doctors may consider alternative treatments and avoid its use unless the benefits outweigh potential complications.

What if I have taken an overdose of Oceva 10mg/ml Injection

Because Oceva 10mg/ml Injection is injected directly by an experienced healthcare professional in a clinical setting, receiving an overdose is extremely unlikely. However, if you experience unusual symptoms, severe pain, or a sudden change in vision after your treatment, contact your eye specialist or seek immediate medical attention.

Diet & Lifestyle Advise

  • Eat lutein-rich foods: Include plenty of dark, leafy greens like spinach, kale, and collard greens in your diet, as they contain nutrients that support retinal health.
  • Quit smoking: Smoking increases oxidative stress in the eyes and is strongly linked to the worsening of macular degeneration and diabetic eye diseases.
  • Wear UV-blocking sunglasses: Protect your eyes from harmful ultraviolet light by wearing sunglasses that filter out 99% to 100% of UVA and UVB rays.
  • Control blood sugar and blood pressure: If you have diabetic retinopathy, maintaining stable blood sugar and blood pressure levels can significantly slow down damage to your retinal blood vessels.
  • Monitor your vision at home: Use an Amsler grid daily (if recommended by your doctor) to check for any new wavy lines or blank spots in your central vision and report changes immediately.
health query

Have a query?

How Soon It Starts Working

The time required for Oceva 10mg/ml Injection to start to work: The time required for Oceva 10mg/ml Injection to show its action is unknown. The time for which the effects of Oceva 10mg/ml Injection last: The duration of action for Oceva 10mg/ml Injection is unknown.

What if you forget to take Oceva 10mg/ml Injection

If you miss an appointment for your injection, contact your eye clinic as soon as possible to reschedule. Keeping your regular appointment schedule is critical to preventing your eye condition from worsening and protecting your vision. Do not wait until your next scheduled visit without speaking to your doctor first.

Storage

•Store Oceva 10mg/ml Injection in a refrigerator at a temperature between 2°C and 8°C (36°F to 46°F).

Drug Warnings

  • Check your vision daily: Monitor the vision in your treated eye by covering the untreated eye to check for any sudden changes, blurs, or blind spots in the days following your injection.
  • Do not drive immediately: Your eye doctor will likely dilate your pupils, and your vision may be blurry or highly sensitive to light after the injection. Arrange for someone else to drive you home safely.
  • Avoid rubbing your eyes: To prevent infection and irritation, do not touch or rub your treated eye for at least 24 hours after receiving the injection.
  • Watch for infection signs: Contact your doctor immediately if you notice worsening eye pain, deep redness, light sensitivity, or any unusual discharge from the eye.
  • Track your appointments: Consistency is key; keep a calendar of your injection appointments to ensure you do not miss a scheduled treatment phase.

Drug-Drug Interactions

verifiedApollotooltip
  • Other intravitreal medications: Using other medications injected into the same eye at the same time may increase the risk of severe eye irritation or alter how Oceva 10mg/ml Injection works. Always consult your doctor before using multiple eye treatments.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip

  • No clinically significant food interactions are known with Oceva 10mg/ml Injection when used as directed. 

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[OPHTHALMOLOGIC AGENTS]

FAQs

Oceva 10mg/ml Injection is used to treat Neovascular (wet) age-related macular degeneration (AMD), macular oedema following retinal vein occlusion (RVO), diabetic macular oedema (DME), proliferative diabetic retinopathy (PDR), and choroidal neovascularization (CNV). Also used in premature babies to treat retinopathy of prematurity (ROP).
Oceva 10mg/ml Injection works by stopping abnormal blood vessel growth and leakage in the eyes that may cause vision loss.
Oceva 10mg/ml Injection may affect fertility. Fertility problems may interfere with the ability to get pregnant or father a child. Consult the doctor if you have any concerns.
Oceva 10mg/ml Injection can be used in the elderly aged 65 years or older if prescribed by the doctor. However, talk to the doctor if you have any concerns.
Oceva 10mg/ml Injection should not be used by individuals who are allergic to any of its active ingredients and those who have an eye infection, eye inflammation, or severe inflammation within the eye. Always consult your healthcare provider before using this medication.
The duration of treatment with Oceva 10mg/ml Injection depends on the condition being treated and your response to the medication. Your healthcare provider will determine the appropriate length of treatment.
After taking Oceva 10mg/ml Injection, inform your doctor if you experience eye pain, discomfort, redness, blurred vision, or increased sensitivity to light. Monitor for signs of infection or retinal detachment, and contact your doctor if these occur. Your doctor may also check eye pressure, as it can temporarily rise. Additionally, inform your doctor if you have a history of eye conditions or stroke-related symptoms.
Oceva 10mg/ml Injection causes side effects such as inflammation of eye, retinal bleeding (bleeding in the back of eye), eye pain, a bloodshot eye, small particles or spots in the vision, eye irritation, dry eye, redness or itching in eye, and increased eye pressure. However, please contact a doctor if these side effects persist for longer durations.
Oceva 10mg/ml Injection is injected directly into the jelly-like part of the eye (the vitreous) by an eye specialist in a sterile clinical environment. Before the injection, your eye is thoroughly cleaned and numbed with drops to ensure you remain comfortable. Talk to your doctor if you have concerns about the procedure.
Most patients feel mild pressure but little to no actual pain during the injection, as your eye doctor will apply numbing eye drops beforehand. You may experience some mild scratchiness or irritation for a day or two afterward. Talk to your doctor if you experience lasting discomfort.
The total number of injections depends entirely on your specific eye condition and how your retina responds to the treatment. Many patients start with monthly injections, which may later become less frequent. Talk to your doctor to understand your personalised treatment plan.
No, you should not drive immediately after your appointment. The numbing drops, pupil dilation, and the injection itself can cause temporary blurry vision and light sensitivity. Please arrange for a friend, family member, or service to drive you home safely. Talk to your doctor if you have questions.
Yes, it is common to see a small red spot on the white of your eye (a minor broken blood vessel) or to notice temporary dark spots or floaters in your vision for a few days. However, if these spots multiply rapidly or are accompanied by flashes of light, seek medical help immediately. Talk to your doctor if you notice any unusual vision changes.
If you miss a scheduled appointment, contact your eye clinic immediately to reschedule. Delaying your injection can cause fluid to build up again in your retina, which could lead to irreversible vision loss. Talk to your doctor to get back on track.
Yes, but you must inform your eye specialist about all other prescription and over-the-counter eye drops you use. Your doctor will advise you on the correct way and timing to use them safely alongside your injections. Talk to your doctor before starting any new eye drops.
The safety of Oceva 10mg/ml Injection in pregnant or breastfeeding women has not been fully studied, so it should only be used if absolutely necessary. You must discuss the potential risks and benefits with your eye specialist before starting treatment. Talk to your doctor if you are pregnant or breastfeeding.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India
Other Info - OC65082
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