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compositionComposition:NORETHISTERONE-5MG
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Prescription Medicine
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Offday Tablet is used to treat heavy, painful, or irregular periods, premenstrual syndrome (PMS), and endometriosis. Additionally, it may be used in the treatment of breast cancer. It contains Norethisterone, which works by restoring the hormone levels in the body. In some cases, this medicine may cause side effects such as unusual vaginal bleeding or spotting, dizziness, dry mouth, constipation, nausea, and diarrhoea. Let the doctor know if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

NORETHISTERONE-5MG

Manufacturer/Marketer :

Wellesta Healthcare Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Offday Tablet

Offday Tablet is an oral prescription medication used to manage heavy periods, painful menstruation, and irregular cycles. It is also commonly prescribed to treat endometriosis and to temporarily delay the onset of a period. By regulating hormone levels in your body, this medicine helps restore a manageable and predictable menstrual cycle.

For best results, you must take Offday Tablet consistently at the same time each day as directed by your healthcare provider. You can take this tablet with or without food, though taking it with a glass of water is recommended. Incorporating a balanced diet and regular, moderate exercise can further support your body's hormonal balance and improve your treatment results.

While taking Offday Tablet , you may experience mild, temporary side effects such as nausea, headaches, or breast tenderness. Most of these symptoms subside as your body adjusts, but you should contact your doctor immediately if you experience severe symptoms like sudden chest pain or shortness of breath.

Talk to your doctor before starting this medicine if you have a history of high blood pressure, diabetes, or migraines. Do not take this if you are pregnant, have active liver damage, a history of blood clots, or unexplained vaginal bleeding.

This medication can interact with certain epilepsy treatments, tuberculosis therapies, and herbal supplements, which may reduce how well it works. Avoid smoking while taking Offday Tablet , as smoking significantly increases your risk of developing serious blood clots. If you are breastfeeding, elderly, or planning a pregnancy, always consult your doctor or pharmacist before starting treatment.

Uses of Offday Tablet

Offday Tablet is used to manage heavy periods, painful menstruation, and irregular cycles. The detailed uses of Offday Tablet are as follows:

  • Heavy menstrual bleeding: Offday Tablet helps control and significantly lighten abnormally heavy or prolonged blood flow during your cycle.
  • Painful periods: It reduces severe cramping, pelvic discomfort, and abdominal pain associated with menstruation.
  • Endometriosis: It works by limiting the abnormal growth of the womb lining outside the uterus, relieving chronic pelvic pain and inflammation.
  • Delaying periods: It temporarily postpones your menstrual cycle for travel, medical procedures, or personal convenience.

Key Benefits

Offday Tablet helps manage heavy and painful menstrual periods by reducing excessive bleeding and relieving menstrual discomfort. With regular use, it supports better energy levels, improves daily comfort, and enhances overall quality of life.

  • Controls Heavy Menstrual Bleeding: By reducing excessive blood loss during menstruation, this medicine helps lower the risk of iron deficiency, reducing fatigue and physical weakness while supporting better energy levels.
  • Relieves Menstrual and Pelvic Pain: This medicine helps ease painful menstrual cramps, pelvic discomfort, and lower back pain associated with conditions such as endometriosis, improving comfort throughout your menstrual cycle.
  • Supports an Active Lifestyle: By reducing heavy bleeding and menstrual pain, this medicine helps improve physical mobility, allowing you to carry out your daily activities with greater confidence and comfort.

Directions for Use

  • Offday Tablet can be taken with or without food, or as advised by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Offday Tablet as a whole with a glass of water.
  • Do not chew, crush or break it.

How Offday Tablet Works

Offday Tablet contains a synthetic version of progesterone, norethisterone, a natural female sex hormone that regulates the monthly menstrual cycle. Under normal conditions, a drop in progesterone levels triggers the shedding of the womb lining, resulting in a period. This medicine works by maintaining steady hormone levels in your body. By mimicking natural progesterone, it prevents the womb lining from growing too quickly or shedding prematurely. This stabilisation helps stop irregular bleeding, lightens heavy cycles, and prevents menstruation entirely for as long as you continue taking the medication under medical supervision.
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Alcohol

Consult your doctor

The interaction of Offday Tablet with alcohol is unknown. Please consult a doctor before consuming alcohol while using Offday Tablet .

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Pregnancy

Unsafe

Offday Tablet is a category X pregnancy drug and is not recommended for use during pregnancy as it may harm the unborn baby. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Consult your doctor

Offday Tablet is given to breastfeeding women only if the doctor thinks benefits are greater than risks. Please consult a doctor if you are breastfeeding.

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Driving

Safe if prescribed

Offday Tablet usually does not affect your ability to drive or operate machinery.

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Liver

Unsafe

Offday Tablet is not recommended if you have liver disease. However, if you have any concerns regarding this, please consult a doctor.

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Kidney

Caution

Take Offday Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Offday Tablet is not recommended for use in children under 18 years.

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Heart

Caution

Offday Tablet should be used with caution in patients with heart problems. Inform your doctor about any heart-related conditions before taking Offday Tablet .

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Geriatrics

Unsafe

Offday Tablet is generally not recommended for elderly patients due to an increased risk of side effects and reduced effectiveness.

What if I have taken an overdose of Offday Tablet

In case of an accidental overdose, seek immediate medical attention. Symptoms of an overdose may include severe nausea, vomiting, dizziness, or unexpected vaginal bleeding.

Diet & Lifestyle Advise

  • Increase iron-rich foods: If you experience heavy bleeding, eat more spinach, lean red meats, beans, and fortified cereals to help prevent anaemia and fatigue.
  • Stay hydrated: Drink plenty of water throughout the day to help reduce bloating and support overall metabolic function.
  • Engage in gentle exercise: Activities like walking, swimming, or yoga can naturally relieve menstrual cramps, improve pelvic blood flow, and boost your mood.
  • Track your symptoms: Keep a detailed diary of your period dates, bleeding intensity, and any side effects to share with your doctor during follow-up visits.
  • Avoid smoking: Smoking while taking hormone treatments significantly increases the risk of serious cardiovascular complications, including blood clots.
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How Soon It Starts Working

  • The time required for Offday Tablet to start to work: The time required for Offday Tablet to show its action is unknown.
  • The time for which the effects of Offday Tablet last: The duration of action for Offday Tablet is clinically unknown.

What if you forget to take Offday Tablet

If you miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a forgotten tablet, as this may increase your risk of side effects. If you are using this medicine to delay your period, a missed dose may cause breakthrough bleeding or spotting.

Storage

•Store Offday Tablet oral tablets at room temperature, ideally below 25°C or 30°C. •Keep the tablets in their original packaging to protect them from direct light and moisture.

Drug Warnings

  • Always confirm with your doctor that Offday Tablet is safe for you if you have a history of blood clots, heart disease, or liver problems.
  • Do not rely on Offday Tablet as a contraceptive unless your doctor has specifically prescribed it for that purpose; use a barrier method like condoms if you need to prevent pregnancy.
  • Stop taking this medicine immediately and contact your doctor if you experience a sudden migraine, visual disturbances, or severe leg pain.
  • Inform your surgeon or dentist that you are taking this medication well in advance of any planned surgeries, as you may need to stop taking it temporarily to lower your risk of blood clots.
  • Check your blood pressure regularly while taking this medication, especially if you have a history of hypertension.

Drug-Drug Interactions

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  • Epilepsy medications: Taking this medicine with drugs like carbamazepine, phenytoin, or phenobarbital may reduce its effectiveness.
  • Tuberculosis treatments: Rifampicin and rifabutin can speed up how your liver processes Offday Tablet , making it less effective.
  • Herbal remedies: St. John’s Wort can lower the levels of this medicine in your body, reducing its ability to control your symptoms.

Drug-Drug Interactions

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How does the drug interact with Offday Tablet:
Coadministration of Offday Tablet with Dabrafenib can reduce the metabolism and decrease the levels of Offday Tablet in the body.

How to manage the interaction:
Taking Offday Tablet with Dabrafenib together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of hot flashes, vaginal dryness, or abnormal bleeding, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Offday Tablet:
Coadministration of Offday Tablet and Mycophenolic acid can decrease the levels and effects of Offday Tablet.

How to manage the interaction:
There could be a possible interaction between Mycophenolic acid and Offday Tablet, but they can be taken together if your doctor has prescribed them. However, if you experience hot flashes, vaginal dryness, or abnormal bleeding consult a doctor. Do not discontinue any medications without a doctor's advice.
NorethisteroneFosphenytoin
Severe
How does the drug interact with Offday Tablet:
Coadministration of Offday Tablet with Fosphenytoin can reduces the blood levels and effects of Offday Tablet .

How to manage the interaction:
Taking Offday Tablet with Fosphenytoin together can result in an interaction, but it can be taken if your doctor has advised it. If you experience symptoms of abnormal bleeding while using birth control, it's important to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
NorethisteroneBoceprevir
Severe
How does the drug interact with Offday Tablet:
Using Boceprevir and Offday Tablet together can reduce the blood levels and decrease the effectiveness of norethindrone.

How to manage the interaction:
Combining Boceprevir with Offday Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like increased hot flashes, vaginal dryness, or menstrual abnormalities, abnormal bleeding, contact the doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Offday Tablet:
Coadministration of Acitretin with Offday Tablet may interfere with the contraceptive effect of Offday Tablet.

How to manage the interaction:
Acitretin and Offday Tablet should be used together only if prescribed by your doctor. Use of at least two methods of effective contraception is mandatory during acitretin therapy and for at least 3 years after stopping therapy.
How does the drug interact with Offday Tablet:
Coadministration of Offday Tablet with Topiramate can reduce the blood levels and effects of norethindrone in the body. This increases the risk of severe bleeding and unintended pregnancy.

How to manage the interaction:
Taking Offday Tablet and topiramate together can result in an interaction; it can be taken if your doctor has advised it. However, if you notice any symptoms of abnormal bleeding, hot flashes or vaginal dryness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Offday Tablet:
Using Felbamate and Offday Tablet together can reduce the blood levels and effects of norethindrone.

How to manage the interaction:
There may be a possibility of interaction between Offday Tablet and Felbamate, but it can be taken if prescribed by a doctor. If you notice any unusual symptoms like changes in your menstrual cycle, excessive bleeding, make sure to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Offday Tablet:
The combined use of Offday Tablet and phenobarbital can reduce the blood levels and effects of Offday Tablet.

How to manage the interaction:
Although taking phenobarbital and Offday Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. If you experience any symptoms like abnormal bleeding, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
NorethisteroneEtretinate
Severe
How does the drug interact with Offday Tablet:
Using Etretinate and Offday Tablet together can cause severe, birth defects. Never use etretinate if you are pregnant. Both a primary and a secondary form of birth control must be used together and for at least 3 years after stopping therapy.

How to manage the interaction:
Although taking Offday Tablet and Etretinate together can cause an interaction, it can be taken if your doctor has suggested it. If you notice any of these signs, make sure to contact your doctor right away. These symptoms may be related to your birth control. Do not stop using any medications without a doctor's advice.
How does the drug interact with Offday Tablet:
Coadministration of Offday Tablet and primidone can reduce the blood levels and effects of Offday Tablet and increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between Offday Tablet and Primidone, they can be taken together if prescribed by a doctor. However, if you experience abnormal bleeding, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No clinically significant food interactions are known with Offday Tablet when used as directed. 

NORETHISTERONE-5MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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NORETHISTERONE-5MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Consuming Grapefruit juice may increase the blood levels of Offday Tablet. Avoid or limit the consumption of grapefruit and grapefruit juice while taking the Offday Tablet dose. Avoid or limit the consumption of grapefruit and grapefruit juice while taking the Offday Tablet dose.

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[PROGESTIN]

FAQs

Offday Tablet is used to treat heavy, painful, or irregular periods, premenstrual syndrome (PMS), and endometriosis. Additionally, Offday Tablet may be used in the treatment of breast cancer.
Offday Tablet contains Norethisterone, a synthetic hormone that mimics the activity of the natural hormone progesterone. Thereby, it restores hormone levels in the body and regulates the growth and shedding of the womb lining. Thus, it helps to treat menstrual disorders.
Offday Tablet may be used to delay periods. Offday Tablet keeps progesterone levels high and prevents shedding of the womb lining. However, please consult a doctor before using Offday Tablet .
Offday Tablet may increase the risk of a blood clot in the veins of the leg, especially if you are overweight, smoke, or have a history of a blood clot in the lungs or veins, repeated miscarriage or have major surgery, serious injury, or systemic lupus erythematosus (autoimmune disease). Therefore, please inform your doctor if you have any of these conditions before taking Offday Tablet .
You are not recommended to take Offday Tablet with rifampicin as it may decrease the levels of Offday Tablet in blood and reduce its effectiveness. However, please consult a doctor before taking Offday Tablet with other medicines.
Periods usually resume within 3 days of discontinuing Offday Tablet . However, please consult a doctor if you have any concerns regarding this.
Offday Tablet may cause changes in blood sugar levels. Therefore, it is advised to regularly monitor blood sugar levels while taking Offday Tablet and inform your doctor if you have diabetes before taking Offday Tablet .
No, Offday Tablet is not a contraceptive on its own.
No, Offday Tablet is unlikely to cause weight loss.
The recommended dosage can vary greatly depending on the reason for taking the medication. It's crucial to follow your doctor's instructions precisely. Taking an incorrect dosage can lead to ineffective treatment or adverse side effects.
No, Offday Tablet does not cause miscarriages. However, it is not safe to take Offday Tablet during pregnancy.
Offday Tablet can generally be taken either before or after a meal. There is no strict requirement regarding the timing of food intake.
Offday Tablet contains Norethisterone, a second-generation progestin.
The duration of Offday Tablet use can vary depending on the specific medical condition being treated.
Yes, Offday Tablet treats irregular menstrual cycles.
Even after taking Offday Tablet and having unprotected sex, one can get pregnant. However, Offday Tablet is a category X pregnancy drug. It is not recommended for use during pregnancy as it may harm the unborn baby. Please consult a doctor if you are pregnant or planning for pregnancy.
Common side effects of Offday Tablet may cause unusual vaginal bleeding or spotting, dizziness, dry mouth, constipation, nausea, diarrhoea, headache, breast pain, and tenderness. Most of these side effects of Offday Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Yes, Offday Tablet can lead to weight gain in some persons. However, it's crucial to remember that this isn't a common adverse effect. The potential risk of weight gain varies based on the individual and the dosage. Talk to your doctor or pharmacist if you are concerned about weight gain or have any other questions regarding norethisterone acetate. They can provide personalized information based on your circumstances.
Limited research is available. Seek medical attention from your doctor if you have any questions. Remember that self-medication can be risky. Always consult with a healthcare professional for proper diagnosis and treatment.
Yes, bleeding may occasionally occur while taking Offday Tablet . If you're experiencing bleeding while on Offday Tablet and you're concerned, it's important to consult with your healthcare provider. They can determine if the bleeding is normal or if there's another underlying issue.
Offday Tablet usually stops irregular bleeding within a few days, but this varies from person to person. If bleeding persists or worsens, consult your doctor.
The duration of Offday Tablet use depends on your specific medical condition and the reason for taking it.
The exact dosage and schedule for Offday Tablet will vary based on your individual health needs. It is important to follow your doctor's instructions to ensure effective treatment and minimize side effects.
If you forget a dose of Offday Tablet , take it as soon as possible. If it's been more than 12 hours, skip the missed dose and continue with your regular schedule or as directed by the physician.
Yes, Offday Tablet can interact with other medications. It's important to avoid taking Offday Tablet with any medications without consulting your doctor first. They can assess the potential risks and benefits and recommend alternative treatments if necessary.
Store in a cool and dry place away from sunlight. Keep Offday Tablet out of reach and out of sight to children.
Offday Tablet can be used to treat long-term disorders like endometriosis. But you should talk to your doctor about the long-term advantages and risks.
There is no direct drug interaction between alcohol and Offday Tablet . However, heavy alcohol consumption can stress your liver and worsen side effects like headache or nausea. It is best to limit alcohol intake while taking this medicine. Talk to your doctor for further guidance.
This medicine is generally not recommended for breastfeeding mothers, as small amounts of the hormone can pass into breast milk and may affect milk production. Always consult your doctor or pharmacist to discuss safer alternatives.
Yes, it is generally safe to take common over-the-counter painkillers like ibuprofen or paracetamol alongside Offday Tablet to manage menstrual cramps or headaches. However, it is always a good practice to talk to your doctor or pharmacist before combining any medications.

Disclaimer

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Country of origin

India

Manufacturer/Marketer address

Unit 3A Level 2, The Centrium, Phoenix Market City Complex,Lbs Road Kurla(W) Mumbai - 400070
Other Info - OFF0054
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