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More about the Product

Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Oflokem-OZ Plus Suspension

Oflokem-OZ Plus Suspension is a combination prescription medicine for treating mixed infections caused by both bacteria and microscopic parasites. It is most commonly used to treat severe stomach and intestinal infections, such as bacterial or parasitic diarrhoea, dysentery, and deep-seated dental or pelvic infections. By clearing out the harmful germs causing these conditions, it helps restore healthy digestive and bodily function.

To get the best results, you must take Oflokem-OZ Plus Suspension exactly as prescribed by your doctor and finish the entire course, even if your symptoms go away after a few doses. It is highly recommended to take this medicine with food to prevent stomach irritation. Staying well-hydrated and resting your digestive system by eating bland foods can also help speed up your recovery.

While taking Oflokem-OZ Plus Suspension, some people may experience mild side effects like a metallic taste, nausea, or a temporary loss of appetite. However, you should contact your doctor right away if you experience severe symptoms, such as sudden tendon pain, numbness or tingling in your hands or feet, or severe skin rashes.

Talk to your doctor or pharmacist before taking Oflokem-OZ Plus Suspension if you have a history of liver damage, kidney disease, nerve disorders, or seizures. Do not take this medicine if you have had a severe allergic reaction to similar antibacterial medicines in the past, or if you have a history of tendon swelling or rupture associated with these treatments.

This medicine can interact strongly with certain substances, particularly alcohol, which can trigger severe vomiting, rapid heartbeats, and headaches. Tell your healthcare provider about all other medicines you are taking, especially blood thinners or antacids. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly individual, consult your doctor before starting this medication.

Uses of Oflokem-OZ Plus Suspension

Oflokem-OZ Plus Suspension may be prescribed to treat the following infections: 

  • Bacterial diarrhoea and dysentery: It targets and eliminates the harmful bacteria and parasites in the digestive tract that cause painful abdominal cramps and loose, watery, or bloody stools.
  • Gastrointestinal infections: It clears mixed infections in the stomach and intestines, helping to relieve bloating, gas, and abdominal pain.
  • Gynaecological infections: It treats infections of the female reproductive system by destroying both oxygen-tolerant and oxygen-sensitive bacteria.
  • Dental infections: It resolves deep tooth abscesses and severe gum infections, relieving severe dental pain and swelling.

Key Benefits

Oflokem-OZ Plus Suspension combines two antimicrobial medicines that work together to treat a broad range of bacterial and parasitic infections. This dual-action approach helps provide effective symptom relief and supports a faster recovery.

  • Provides Broad-Spectrum Infection Control: Helps treat mixed infections caused by both bacteria and parasites, offering comprehensive infection management.
  • Simplifies Treatment: Combines two active ingredients into a single medicine, making treatment more convenient and easier to follow.
  • Relieves Digestive Symptoms: Helps reduce symptoms such as abdominal cramps, diarrhoea, and discomfort associated with gastrointestinal infections.
  • Promotes Faster Recovery: By controlling the infection quickly, it helps reduce inflammation and supports a quicker return to normal daily activities.
  • Prevents Infection Spread: Helps stop the growth and spread of infection-causing organisms, reducing the risk of complications.

Directions for Use

Always take Oflokem-OZ Plus Suspension exactly as prescribed by your doctor. Do not change your dose or stop taking it early without consulting them.

  • Swallow the tablet whole with a full glass of water.
  • Do not crush, chew, or break the tablet, as this can affect how the medicine is absorbed and cause an unpleasant taste.
  • Take this medicine with food or immediately after a meal to protect your stomach from irritation or nausea.
  • Space your doses evenly throughout the day to keep a constant level of the medicine in your system.

How Oflokem-OZ Plus Suspension Works

Oflokem-OZ Plus Suspension contains two active bacterial-fighting ingredients, ofloxacin and metronidazole, that work together to destroy infection-causing organisms. The first active component, ofloxacin, belongs to a class of medicines called fluoroquinolone antibiotics. It works by blocking a vital bacterial enzyme needed for copying and repairing bacterial DNA. Without this enzyme, the bacteria cannot multiply and eventually die. The second active component, metronidazole, belongs to the nitroimidazole class of antimicrobials. It specifically targets anaerobic bacteria (which thrive in environments without oxygen, like the gut) and single-celled parasites. When this component enters the microbial cell, it undergoes a chemical change that damages the cell's DNA, causing immediate cell death. Together, these two mechanisms provide a thorough sweep of the infected area, ensuring no resistant germs are left behind.
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Alcohol

Unsafe

Alcohol should not be consumed while taking Oflokem-OZ Plus Suspension, as it may increase the risk of side effects like dizziness and drowsiness.

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Pregnancy

Unsafe

Oflokem-OZ Plus Suspension should not be taken during pregnancy, especially during the first trimester, as it may cause harm to the fetus. If you become pregnant while taking Oflokem-OZ Plus Suspension, stop taking the medication, and contact your doctor immediately.

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Breast Feeding

Unsafe

Oflokem-OZ Plus Suspension may pass into the breast milk, so avoid taking Oflokem-OZ Plus Suspension while breastfeeding.

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Driving

Unsafe

Oflokem-OZ Plus Suspension can cause dizziness, confusion, and drowsiness. Therefore, avoid driving or operating machinery unless you are mentally alert and competent.

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Liver

Consult your doctor

Oflokem-OZ Plus Suspension to be taken with caution, especially if you have a history of liver diseases. The dose may have to be adjusted by your doctor.

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Kidney

Consult your doctor

Oflokem-OZ Plus Suspension to be taken with caution, especially if you have a history of kidney diseases. The dose may have to be adjusted by your doctor.

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Children

Safe if prescribed

Oflokem-OZ Plus Suspension can be given to the children if prescribed by a doctor.

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Heart

Consult your doctor

Please consult your doctor before using Oflokem-OZ Plus Suspension if you have pre-existing heart problems.

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Geriatrics

Consult your doctor

Please consult a doctor before giving Oflokem-OZ Plus Suspension to geriatric patients.

What if I have taken an overdose of Oflokem-OZ Plus Suspension

In case of an accidental overdose, seek immediate medical attention or contact a local poison control centre. Symptoms of an overdose may include severe dizziness, nausea, vomiting, confusion, or fits (seizures).

Diet & Lifestyle Advise

  • Stay hydrated: Drink plenty of fluids, such as water, clear broths, or oral rehydration solutions (ORS), to replace lost fluids and prevent dehydration caused by diarrhoea.
  • Avoid all alcohol: Do not consume alcohol during your treatment and for at least 3 days after finishing Oflokem-OZ Plus Suspension to avoid severe, dangerous interactions.
  • Eat simple, bland foods: Stick to easily digestible foods like rice, bananas, applesauce, and plain toast. Avoid dairy products, spicy dishes, and highly fatty foods until your digestive tract has fully recovered.
  • Protect yourself from the sun: This medicine can make your skin highly sensitive to sunlight. Wear protective clothing, sunglasses, and a broad-spectrum sunscreen when spending time outdoors.
health query

Have a query?

How Soon It Starts Working

The time required for Oflokem-OZ Plus Suspension to start to work: The time required for Oflokem-OZ Plus Suspension to show its action is unknown. The time for which the effects of Oflokem-OZ Plus Suspension last: The duration of action for Oflokem-OZ Plus Suspension is unknown.

What if you forget to take Oflokem-OZ Plus Suspension

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Storage

• Store Oflokem-OZ Plus Suspension tablets at room temperature, ideally between 15°C and 30°C (59°F to 86°F). • Keep the medicine in its original packaging to protect it from direct light, high heat, and moisture.

Drug Warnings

  • Complete the Full Course: Do not skip doses or stop taking Oflokem-OZ Plus Suspension early, even if you feel better, as this may cause the infection to return and increase the risk of antibiotic resistance.
  • Inspect Before Use: Check the medication packaging before use and do not take the tablets if the blister seal is broken or the tablets appear damaged or discoloured.
  • Avoid Certain Antacids and Supplements: Do not take antacids containing magnesium or aluminium, or supplements containing iron, calcium, or zinc, within two hours of taking this medicine, as they may reduce its absorption.
  • Watch for Tendon Problems: Rest the affected area and contact your doctor immediately if you develop sudden pain, swelling, or tenderness in a tendon, particularly around the ankle, knee, or wrist.
  • Use Caution When Driving: Avoid driving, operating machinery, or performing tasks that require alertness if you feel dizzy or lightheaded after taking this medicine.

Drug-Drug Interactions

verifiedApollotooltip

Inform your doctor if you are taking any of the following medicines, as they may interact with Oflokem-OZ Plus Suspension: 

  • Blood thinners (like warfarin): Taking these together can increase the risk of bleeding by enhancing the blood-thinning effect.
  • Antacids and mineral supplements: Compounds containing magnesium, aluminium, iron, or zinc can bind to the medicine, significantly reducing its absorption.
  • Seizure medications (like phenytoin): May increase the levels of these drugs in your body, leading to toxicity.
Critical

Drug-Drug Interactions

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Critical
How does the drug interact with Oflokem-OZ Plus Suspension 30 ml:
Using Mesoridazine together with Oflokem-OZ Plus Suspension 30 ml can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Mesoridazine with Oflokem-OZ Plus Suspension 30 ml is not recommended, please consult a doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
How does the drug interact with Oflokem-OZ Plus Suspension 30 ml:
Co-administration of Oflokem-OZ Plus Suspension 30 ml with Thioridazine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Oflokem-OZ Plus Suspension 30 ml with Thioridazine together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain, or tightness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Oflokem-OZ Plus Suspension 30 ml:
Co-administration of Oflokem-OZ Plus Suspension 30 ml with Ziprasidone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Oflokem-OZ Plus Suspension 30 ml with Ziprasidone together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or chest pain, ontact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Oflokem-OZ Plus Suspension 30 ml:
Co-administration of Oflokem-OZ Plus Suspension 30 ml with Dronedarone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Oflokem-OZ Plus Suspension 30 ml with Dronedarone together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or chest pain, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Oflokem-OZ Plus Suspension 30 ml:
Co-administration of Oflokem-OZ Plus Suspension 30 ml with Saquinavir can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Oflokem-OZ Plus Suspension 30 ml with Saquinavir together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or chest pain, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Oflokem-OZ Plus Suspension 30 ml:
Co-administration of Oflokem-OZ Plus Suspension 30 ml with Sotalol can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Oflokem-OZ Plus Suspension 30 ml with Sotalol together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. If you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain, or tightness, contact a doctor. Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Oflokem-OZ Plus Suspension 30 ml:
Co-administration of Oflokem-OZ Plus Suspension 30 ml with Quinidine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Oflokem-OZ Plus Suspension 30 ml with Quinidine together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or chest pain, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Oflokem-OZ Plus Suspension 30 ml:
Co-administration of Oflokem-OZ Plus Suspension 30 ml with Disopyramide can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Oflokem-OZ Plus Suspension 30 ml with Disopyramide together is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Oflokem-OZ Plus Suspension 30 ml:
Using Bepridil together with Oflokem-OZ Plus Suspension 30 ml drugs can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Oflokem-OZ Plus Suspension 30 ml with Bepridil can cause an interaction, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats. Do not stop using any medications without consulting a doctor.
How does the drug interact with Oflokem-OZ Plus Suspension 30 ml:
The combination of Amiodarone and Oflokem-OZ Plus Suspension 30 ml may significantly increase the risk of an abnormal heart rhythm.

How to manage the interaction:
Although Amiodarone and inOrnidazole + Ofloxacin teract, it can be taken if prescribed by a doctor. If you get dizziness, lightheadedness, fainting, or fast or racing heartbeats, consult a doctor. Do not stop taking any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip

The following foods and beverages may interact with Oflokem-OZ Plus Suspension and affect its safety or effectiveness: 

  • Alcohol: Can cause a severe, highly uncomfortable reaction characterised by rapid heart rate, low blood pressure, severe headache, and vomiting.
  • Caffeine: This medicine can slow down how your body processes caffeine, making you feel anxious, shaky, or experience a racing heart.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Oflokem-OZ Plus Suspension is a combination of two antibiotics that include Ofloxacin and Metronidazole. Ofloxacin prevents the division of bacterial cells and inhibits their repair mechanism, leading to the death of the bacteria. Metronidazole kills parasites and anaerobic bacteria that cause infections. It works by damaging their DNA. Both antibiotics are bactericidal in nature and work together to treat the infection effectively.
Oflokem-OZ Plus Suspension is a combination of antibacterial (ofloxacin) and anti-amoebic (metronidazole) medication used to treat various infections caused by bacteria. It is also effective in treating diarrhoea due to mixed infections and amoebic dysentery.
It is not advised to take alcohol with Oflokem-OZ Plus Suspension. Taking alcohol while taking Oflokem-OZ Plus Suspension can cause serious side effects such as headaches, feeling or being sick, pain in the stomach, hot flushes, a fast or irregular heartbeat, dizziness, drowsiness, etc.
Oflokem-OZ Plus Suspension can make your skin sensitive to sunlight, a condition known as photosensitivity. So, prolonged exposure to sunlight or ultraviolet light should be avoided. In the event of an emergency, always wear sunscreen before going outdoors.
If you miss a dose of Oflokem-OZ Plus Suspension, take it as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for the missed one.
No. Oflokem-OZ Plus Suspension is an antibacterial medicine that acts only against bacterial infections, not against viral infections. You should not take it without consulting your doctor first. Self-medication is dangerous and can lower the efficacy of Oflokem-OZ Plus Suspension, leading to antibiotic resistance.
Yes, intake of Oflokem-OZ Plus Suspension may cause dry mouth, and you may feel thirsty frequently. Try to drink plenty of fluids (water with electrolytes) and probiotics. You may also experience dry lips, for which you can use lip balm.
Avoid intake of Oflokem-OZ Plus Suspension if you have a history of liver diseases, low blood white cells (leukopenia), seizures (fits), gastrointestinal diseases (like Crohn's disease, Inflammatory bowel disease), and other neurological diseases.
The common side effects of Oflokem-OZ Plus Suspension include nausea, vomiting, stomach upset, loss of appetite, dry mouth, a metallic taste, headache, dizziness, drowsiness, and confusion. Most of these side effects of Oflokem-OZ Plus Suspension do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.
This medicine is generally not recommended during pregnancy or breastfeeding unless your doctor decides the benefits outweigh the potential risks. Some of the active ingredients can cross the placenta and pass into breast milk. Talk to your doctor or pharmacist to discuss safer options.
A metallic taste is a very common and temporary side effect of this medicine. It is completely harmless and will go away once your treatment is complete. You can manage this by brushing your teeth regularly, using mouthwash, or chewing sugar-free gum.
No. Antacids containing aluminium, magnesium, or calcium can bind to this medicine in your stomach, preventing it from being absorbed properly and reducing its strength. Take your antacid at least 2 hours before or 2 hours after taking Oflokem-OZ Plus Suspension.
If you stop taking the medicine too early, the strongest bacteria and parasites may survive and multiply again. This can cause your infection to return worse than before and make the germs resistant to future antibiotic treatments. Always complete the full course prescribed.
Yes, one of the drug classes in Oflokem-OZ Plus Suspension is associated with a rare but serious risk of tendon inflammation or tendon rupture. If you experience sudden joint pain, swelling, or stiffness, stop exercising immediately, avoid putting weight on the area, and contact your doctor.
If you develop severe, watery diarrhoea, especially with stomach cramps and a fever, do not take any over-the-counter anti-diarrhoeal medicines. This could be a sign of a serious secondary bowel infection. Contact your doctor immediately for an evaluation.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - OFL0510
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