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compositionComposition:OFLOXACIN-0.3%
prescription
Prescription Medicine
info
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Ofloren 0.3% Drop is used to treat infections caused by bacteria including pneumonia, gonorrhoea (a sexually transmitted disease), typhoid fever, infectious diarrhoea, and infections of the skin, eye/ear, bone, joint, abdomen, and prostate (male reproductive gland). It contains Ofloxacin, which works by killing bacteria that cause infections and preventing the further spread of the infection. In some cases, you may experience sleep problems, headache, dizziness, nausea, vomiting, diarrhoea, itching, external genital itching in women, vaginal inflammation (vaginitis) and taste changes. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions. Do not take this medicine with dairy products as it may lower its efficacy.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

OFLOXACIN-0.3%

Manufacturer/Marketer :

Indoco Remedies Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Ofloren 0.3% Drop

Ofloren 0.3% Drop is a prescription medication used to treat a variety of bacterial infections in the body. It belongs to a class of medicines called fluoroquinolone antibiotics, which work by stopping the growth of harmful bacteria. Doctors commonly prescribe it for infections of the urinary tract, lungs, prostate, and skin.

To clear your infection completely, you must take Ofloren 0.3% Drop regularly at the exact times prescribed by your doctor, even if you start feeling better. It is usually taken once or twice daily and can be taken with or without food.

Do not take Ofloren 0.3% Drop at the same time as dairy products, calcium-fortified foods, antacids, or mineral supplements, as they can reduce how much medicine your body absorbs. Take Ofloren 0.3% Drop at least 2 hours before or 2 hours after these products. Staying well-hydrated by drinking plenty of water during your treatment is a highly helpful lifestyle habit that supports your kidneys while taking this medicine.

While taking Ofloren 0.3% Drop, you might experience mild side effects like nausea, diarrhoea, or headache. However, you must contact your doctor immediately if you experience serious issues such as severe joint or tendon pain, numbness, tingling, or sudden changes in your mood or sleep patterns.

Talk to your doctor before taking Ofloren 0.3% Drop if you have a history of tendon problems, nerve disorders, kidney disease, or myasthenia gravis. Do not take this medicine if you have ever had a severe allergic reaction to similar antibiotics, or if you have a history of tendon swelling or tearing caused by this class of drugs.

This medicine can interact with multivitamin supplements, antacids containing magnesium or aluminium, and iron pills, which can stop your body from absorbing the medicine properly. You should also limit alcohol intake as it can worsen dizziness, and consult your doctor if you are pregnant, breastfeeding, or over the age of 65 before starting treatment.

Uses of Ofloren 0.3% Drop

Ofloren 0.3% Drop may be prescribed to treat the following bacterial infections: 

  • Urinary tract infections (UTIs): Ofloren 0.3% Drop helps clear bacterial infections of the bladder and kidneys by stopping the bacteria from multiplying.
  • Respiratory tract infections: It treats lung infections like bacterial bronchitis and pneumonia by targeting and eliminating the responsible bacteria.
  • Prostate infections: It penetrates prostate tissue effectively to resolve long-term or sudden bacterial inflammation of the prostate gland.
  • Skin and soft tissue infections: It destroys bacteria causing deep or superficial skin infections, helping your skin heal.

Key Benefits

Ofloren 0.3% Drop helps treat bacterial infections and supports recovery in several ways: 

  • Treats Bacterial Infections: Effectively targets and eliminates bacteria responsible for a variety of infections.
  • Relieves Infection Symptoms: Helps reduce symptoms such as pain, fever, burning during urination, coughing, and other infection-related discomforts.
  • Promotes Faster Recovery: By controlling bacterial growth, it helps the body recover more quickly and return to normal daily activities.
  • Prevents Infection Progression: Helps stop the spread and worsening of bacterial infections when taken as prescribed.
  • Reduces the Risk of Recurrence: Completing the full course of treatment helps ensure that harmful bacteria are eliminated and may reduce the risk of the infection returning or developing antibiotic resistance.

Directions for Use

To use Ofloren 0.3% Drop safely and effectively, follow these instructions: 

  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet.
  • You can take this medicine with or without food, but try to take it at the same times each day to keep a constant level of medicine in your body.
  • Avoid taking this medicine at the same time as antacids, iron supplements, multivitamins, or dairy products (like milk or yoghurt), as they can block its absorption. Take Ofloren 0.3% Drop either 2 hours before or 2 hours after these substances.
  • Drink plenty of fluids throughout the day while taking this medicine to protect your kidneys.

Always follow your doctor's exact instructions regarding the duration of your treatment. Even if your symptoms disappear, continue taking the medication until the full prescribed course is finished.

How Ofloren 0.3% Drop Works

The active ingredient in Ofloren 0.3% Drop, ofloxacin, belongs to the fluoroquinolone class of antibiotics and works by targeting essential enzymes inside bacterial cells. It blocks two enzymes known as DNA gyrase (topoisomerase II) and topoisomerase IV, which bacteria need to copy, repair, and replicate their DNA. Without these enzymes, bacteria cannot multiply, repair damaged genetic material, or survive. Because human cells do not rely on these bacterial enzymes, Ofloren 0.3% Drop selectively targets infection-causing bacteria while leaving human cells largely unaffected. This helps stop the infection from spreading and allows your immune system to clear the remaining bacteria.
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Alcohol

Unsafe

Alcohol is not known to cause any unpleasant side effects if taken along with Ofloren 0.3% Drop. But intake of alcohol with Ofloren 0.3% Drop may damage your liver. So intake of Ofloren 0.3% Drop should be avoided with Ofloren 0.3% Drop.

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Pregnancy

Unsafe

Ofloren 0.3% Drop is a pregnancy Category C medicine. It is not known whether Ofloren 0.3% Drop will affect pregnant women or fetus or not. Hence, the intake of Ofloren 0.3% Drop should be avoided if you are pregnant or planning to become pregnant as it may harm the baby.

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Breast Feeding

Caution

Ofloren 0.3% Drop is excreted in human milk. But the amount of Ofloren 0.3% Drop absorbed by the nursing infant is unknown. So, it should not be taken while breastfeeding.

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Driving

Caution

Ofloren 0.3% Drop can affect alertness and coordination. So, operating machinery which requires concentration should be avoided.

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Liver

Caution

Ofloren 0.3% Drop to be taken with caution, especially if you have a history of liver diseases/conditions. Your doctor may have to adjust the dose if there are symptoms of nausea, vomiting, loss of appetite, dark-colored urine, yellowing of or skin/eye.

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Kidney

Caution

Ofloren 0.3% Drop to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Safe if prescribed

Ofloren 0.3% Drop can be given to children but under child specialist medical supervision. Ofloren 0.3% Drop is prescribed to the children to treat complicated urinary tract infections, anthrax infection, or plague infection.

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Heart

Consult your doctor

Please consult your doctor before using Ofloren 0.3% Drop if you have pre-existing heart problems. Your doctor will prescribe Ofloren 0.3% Drop if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Please consult a doctor before giving Ofloren 0.3% Drop to geriatric patients. Your doctor will prescribe Ofloren 0.3% Drop if the benefits outweigh the risks.

What if I have taken an overdose of Ofloren 0.3% Drop

In case of an accidental overdose, seek immediate medical attention or contact a poison control centre right away. Symptoms of an overdose may include severe dizziness, confusion, seizures, or stomach upset.

Diet & Lifestyle Advise

  • Stay well-hydrated: Drink 8 to 10 glasses of water daily to help prevent the medicine from forming crystals in your urine.
  • Avoid direct sunlight: This medicine makes your skin highly sensitive to UV rays. Wear protective clothing, hats, and a broad-spectrum sunscreen when outdoors, and avoid tanning beds.
  • Separate calcium and dairy: Do not eat calcium-rich foods (like milk, yoghurt, or calcium-fortified juices) at the same time as Ofloren 0.3% Drop, as they significantly lower the medicine's effectiveness.
  • Rest your joints: Avoid strenuous exercise or heavy lifting during your treatment, as fluoroquinolone medicines can weaken tendons and increase the risk of injury.
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Have a query?

How Soon It Starts Working

The time required for Ofloren 0.3% Drop to start to work: Ofloren 0.3% Drop ideally shows its action within 1 to 2 hours after administration. The time for which the effects of Ofloren 0.3% Drop last: The effect of Ofloren 0.3% Drop lasts for 2 days.

What if you forget to take Ofloren 0.3% Drop

If you miss a dose, take it as soon as you remember. However, if your next scheduled dose is only a few hours away, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store Ofloren 0.3% Drop at controlled room temperature, ideally between 20°C and 25°C (68°F to 77°F). • Keep the medication in its original container, tightly closed, to protect it from direct light, heat, and moisture.

Drug Warnings

  • Check your tendons: Stop taking Ofloren 0.3% Drop immediately and contact your doctor if you experience sudden pain, snapping, or swelling in a tendon or joint.
  • Watch for nerve pain: Discontinue the medicine and alert your healthcare provider if you experience numbness, tingling, or a 'pins and needles' sensation in your hands or feet.
  • Inspect the tablets: Always inspect your tablets before taking them; do not use them if the packaging is damaged, or if the tablets are discoloured or crumbling.
  • Monitor your blood sugar: If you have diabetes, monitor your blood sugar closely, as this medicine can cause sudden shifts in blood glucose levels.
  • Avoid driving if dizzy: Do not drive, operate machinery, or perform tasks requiring mental alertness until you know how this medication affects you.

verifiedApollotooltip

Inform your doctor if you are taking any of the following medicines, as they may interact with Ofloren 0.3% Drop: 

  • Antacids, iron, and zinc supplements: Taking these alongside Ofloren 0.3% Drop can bind the antibiotic in your gut, severely reducing how much of the medicine your body absorbs.
  • Blood thinners (like warfarin): Combining these can increase the effect of the blood thinner, raising your risk of bleeding.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs): Taking painkillers like ibuprofen with Ofloren 0.3% Drop can increase the risk of central nervous system stimulation and seizures.
  • Diabetes medications: Can interact to cause unpredictable shifts in blood sugar levels, increasing the risk of low blood sugar.

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verifiedApollotooltip

Certain foods and beverages may affect how Ofloren 0.3% Drop works or increase the risk of side effects:

  • Dairy products and calcium-fortified foods: Consuming these alone with the medicine can block its absorption, making the treatment less effective.
  • Caffeine: This medicine can slow down how your body processes caffeine, leading to increased jitteriness, a rapid heartbeat, or sleep issues.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Ofloren 0.3% Drop is used to treat bacterial infections, including pneumonia, gonorrhoea (a sexually transmitted disease), typhoid fever, infectious diarrhoea, and infections of the skin, eye/ear, bone, joint, abdomen, and prostate (male reproductive gland).
If you miss a dose of Ofloren 0.3% Drop, take the missed dose as soon as you remember it. However, if it's almost time for the next dose, do not take a double dose to make up for a missed one.
No, Ofloren 0.3% Drop should not be taken along with dairy products as it might affect the absorption and efficacy of Ofloren 0.3% Drop. However, you can take it with a meal that includes these foods or drinks.
Ofloren 0.3% Drop makes your skin sensitive to sunlight known as photosensitivity. So, prolonged exposure to sunlight or ultraviolet light should be avoided. In case of emergency, you should always wear sunscreen before going out.
Yes, after taking Ofloren 0.3% Drop, you may have diarrhea. Ofloren 0.3% Drop is an antibiotic that kills or prevents bacterial growth, so in case some good intestinal bacteria which aid in digestion might also get killed. So, drink plenty of fluids and take probiotics to prevent excessive loss of fluids from the body (dehydration).
No, Ofloren 0.3% Drop should be taken in the dose and duration as advised by the doctor. If you take it in more than the recommended dose, it might cause unpleasant side effects. If you think your symptoms are not improving, please consult your doctor
You are recommended to take Ofloren 0.3% Drop either 2 hours before or 2 hours after taking an antacid, multivitamin, or other product that has calcium/magnesium/aluminium/iron/zinc, antiulcer agent (sucralfate) or anti-HIV drug (didanosine).
If you experience joint or tendon pain, stop taking the medication immediately, avoid physical activity, and contact your doctor right away. This is a known safety precaution as this class of medicine can affect tendons. Talk to your doctor for an alternative treatment.
It is highly recommended to avoid or severely limit alcohol while taking this medicine. Alcohol can increase side effects like dizziness, lightheadedness, and drowsiness, making daily tasks unsafe. Talk to your doctor if you have concerns about alcohol use.
No, you must finish the entire course prescribed by your doctor even if you feel completely better. Stopping early can allow the remaining bacteria to multiply again, causing the infection to return and potentially become resistant to antibiotics. Talk to your doctor before stopping the medication.
No, Ofloren 0.3% Drop is an antibiotic and only treats bacterial infections. It has no effect on viruses, and using it for viral infections like colds or the flu will not help and can lead to antibiotic resistance. Talk to your doctor about appropriate treatments for viral symptoms.
This medicine is generally not recommended during pregnancy or breastfeeding unless your doctor decides the benefits clearly outweigh the risks. It may affect bone and joint development in the developing baby. Talk to your doctor to discuss safer alternatives.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. MedlinePlus. A691005 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026]Check here
  2. Drugs.com Clinical Review Team. Ofloxacin Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  3. Ofloxacin [EMC SmPC]. 2016. [Accessed on 01 Apr. 2019]Check here
  4. Ofloxacin [Prescribing Information]. 2008. [Accessed on 01 Apr. 2019]Check here
  5. David G. Bailey, George Dresser and J. Malcolm O. Arnold, MB. National Library of Medicine (NIH). Grapefruit–medication interactions: Forbidden fruit or avoidable consequences. [Revised in 18th October 2018] [Accessed on 3rd May 2022]Check here
  6. Cologne, Germany: Institute for Quality and Efficiency in Health Care (IQWiG). National Library of Medicine (NIH). Using medication: Using antibiotics correctly and avoiding resistance. [Revised in 13th December 2013] [Accessed on 3rd May 2022]Check here
  7. Gerard Laboratories. Electronic Medicines Compendium (EMC). [Revised in November 2021] [Accessed on 3rd May 2022]Check here

Country of origin

India
Other Info - OF46119
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