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Composition :

OFLOXACIN-200MG+ORNIDAZOLE-500MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Oflotas OZ Tablet

Oflotas OZ Tablet is a prescription combination medicine used to treat bacterial and parasitic infections, primarily in the gastrointestinal tract. It is commonly prescribed to manage conditions like infectious diarrhoea, dysentery, and certain pelvic or gynecological infections. By targeting two different types of disease-causing organisms, it helps resolve infections thoroughly.

For this medicine to work effectively, you must take it consistently and at the same times every day as directed by your healthcare provider. It is highly recommended to take Oflotas OZ Tablet with food or immediately after a meal to help protect your stomach from irritation. During your recovery, simple lifestyle adjustments like drinking plenty of clean fluids and eating easily digestible meals can support your body's healing process.

While taking Oflotas OZ Tablet , some people may experience mild side effects such as nausea, dizziness, or a temporary metallic taste in the mouth. These effects are usually temporary, but you should contact your doctor immediately if you experience severe symptoms like tingling in your hands or feet, tendon pain, or severe skin rashes.

Do not take this medicine if you have a known allergy to similar antibiotics, or if you have a history of tendon problems or nerve disorders. It is critical to talk to your doctor before starting Oflotas OZ Tablet if you have a history of seizures, liver damage, kidney issues, or heart rhythm abnormalities.

You must completely avoid alcohol while taking this medicine and for at least three days after completing your treatment, as combining them can cause severe vomiting, rapid heartbeats, and headaches. Always consult your doctor before using this medicine if you are pregnant, breastfeeding, or planning a pregnancy.

Uses of Oflotas OZ Tablet

Oflotas OZ Tablet is a combination medicine used to treat a variety of bacterial and parasitic infections affecting the gastrointestinal and urinary systems:

Infectious Diarrhoea and Dysentery: It targets and clears the bacterial and parasitic pathogens responsible for severe, watery, or bloody stools.
Gastrointestinal Infections: It treats infections in the stomach and intestines, helping to relieve abdominal cramps and inflammation.
Gynecological and Pelvic Infections: It helps clear complicated infections of the reproductive tract caused by susceptible anaerobic and aerobic bacteria.
Urinary Tract Infections: It is used to resolve deep-seated bacterial infections of the urinary system.

Key Benefits

The following benefits make Oflotas OZ Tablet effective in managing mixed bacterial and parasitic infections:

Broad-Spectrum Action: It works against both bacteria and protozoa, ensuring comprehensive treatment of mixed infections affecting the gut and urinary tract.
Faster Symptom Relief: Helps reduce diarrhoea, abdominal cramps, and discomfort by targeting the underlying infection.
Prevents Infection Spread: Controls the growth and spread of harmful microorganisms, reducing the risk of complications or recurrence.
Supports Quick Recovery: By eliminating the causative organisms, it helps restore normal digestive and urinary function more quickly, allowing earlier return to daily activities.

Side effects of Oflotas OZ Tablet

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Trouble Falling/ Staying Asleep

Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:

Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
Try relaxing techniques like deep breathing, mindfulness meditation and any others.
Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Dizziness

Here are the 7 steps to manage Dizziness caused by medication:

Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
When standing up, do so slowly and carefully to avoid sudden dizziness.
Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Loose And Watery Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Vomiting

To prevent, manage, and treat Constipation caused by medication usage, follow these steps:

Preventing Vomiting (Before it Happens)
Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
Having a small meal before taking your medication can help reduce nausea and vomiting.
Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
Managing Vomiting (If it Happens)
Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
What to Do if Vomiting Persists
Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Less Hunger

Consume more protein-rich foods and healthy fats like beans, avocados, cheese, nuts and lean meats to minimize appetite.
Prefer foods high in fiber to help feel full for a long time.
If you have decreased appetite, eat only when you are hungry.
Eat several small meals or snacks all day.
Try to take only small sips of fluids while eating.

Directions for Use

Always follow your doctor's precise instructions when taking this medication. Below are the standard guidelines for using Oflotas OZ Tablet safely:

Swallow the tablet whole with a full glass of water. Do not crush, chew, or break it, as this can affect how the medicine is absorbed.
Take the tablet with food or right after a meal to minimise stomach upset.
Try to take your doses at evenly spaced intervals at the same times each day.
Complete the entire course of treatment prescribed by your doctor, even if your symptoms clear up after a few doses. Stopping the medicine too early may allow the infection to return and make the bacteria resistant to future treatments.

How Oflotas OZ Tablet Works

Oflotas OZ Tablet contains ofloxacin and ornidazole, which work together through a dual-action mechanism to treat mixed bacterial and protozoal infections. Ofloxacin is a fluoroquinolone antibiotic that works by inhibiting bacterial DNA replication. It blocks key enzymes required for DNA repair and duplication, preventing bacteria from multiplying and ultimately leading to their death. Ornidazole is an antiprotozoal and antibacterial agent that targets anaerobic organisms. It enters microbial cells and disrupts their DNA structure from within, stopping their ability to grow and spread the infection. Together, these two components provide broad-spectrum coverage by acting on both aerobic and anaerobic organisms, helping to effectively eliminate mixed infections and support faster recovery.

Alcohol

Unsafe

Avoid consuming alcohol while taking Oflotas OZ Tablet as it may cause increased dizziness.

Pregnancy

Consult your doctor

Please consult your doctor if you are pregnant; your doctor will prescribe Oflotas OZ Tablet only if the benefits outweigh the risks.

Breast Feeding

Consult your doctor

Consult your doctor before taking Oflotas OZ Tablet if you are breastfeeding. Your doctor will decide if Oflotas OZ Tablet can be taken by breastfeeding mothers or not.

Driving

Caution

Oflotas OZ Tablet may cause dizziness and drowsiness. So, drive only if you are alert.

Liver

Consult your doctor

Dose adjustment may be needed. Please consult your doctor before taking Oflotas OZ Tablet if you have liver impairment/liver disease.

Kidney

Consult your doctor

Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease before taking Oflotas OZ Tablet .

Children

Unsafe

Oflotas OZ Tablet is not recommended for children as safety and effectiveness have not been established.

Heart

Caution

Oflotas OZ Tablet can be used in heart patients if prescribed by the physician. Please consult your physician if you have any concerns.

Geriatrics

Caution

Oflotas OZ Tablet should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using Oflotas OZ Tablet .

What if I have taken an overdose of Oflotas OZ Tablet

Do not take more than the prescribed dose of Oflotas OZ Tablet as it may cause overdose. The symptoms of overdose include dizziness, confusion, convulsive seizures, nausea, mucosal erosions and impairment of consciousness. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

Stay hydrated: Drink plenty of clean water, clear broths, or oral rehydration solutions to replace fluids lost from diarrhoea.
Eat bland foods: Stick to easy-to-digest items like bananas, plain rice, applesauce, and toast to avoid irritating your stomach.
Be mindful with dairy and caffeine: You do not need to avoid dairy completely. However, avoid taking high-calcium supplements or antacids at the same time as your dose. Caffeine intake may need moderation if you experience jitteriness or palpitations during treatment.
Get adequate rest: Give your body plenty of downtime to help your immune system fight off the infection.

Health Queries

I am suffering from severe fever with chills and frequent loose motions. How should it be treated?

G.santoshini Reddy

M Pharmacy (Pharmaceutics)

Severe fever with chills and frequent loose motions is most often caused by a significant stomach or intestinal infection, and sometimes by food or water contamination, so the most important step is to prevent dehydration and seek proper medical care. Drink plenty of fluids like oral rehydration solution (ORS), clean water, coconut water, or clear soups in small, frequent sips, as the body loses a lot of water and salts through diarrhoea and fever. Eat light, easily digestible foods such as rice, curd, bananas, khichdi, toast, or boiled vegetables, and avoid oily, spicy, and outside food until recovery. Paracetamol can help reduce fever and body aches, but it should be taken in the correct dose and not overused. Do not take antibiotics or strong anti-diarrheal medicines on your own, as the treatment depends on the exact cause of infection. You should consult a doctor urgently if the fever is very high, chills are severe, there is blood in the stools, persistent vomiting, severe abdominal pain, signs of dehydration like dizziness or reduced urination, or if symptoms continue beyond 1-2 days without improvement. In some cases, stool tests or blood tests may be needed to identify the infection and guide proper treatment. With timely care, fluids, rest, and correct medication when needed, most people recover well.

For the past few days, I have had frequent motions and feel a burning sensation when passing stools. What should I do?

Vikas Singh

M Pharmacy

Frequent motions with a burning sensation can be due to gut irritation or a mild infection. Drink plenty of fluids to prevent dehydration and take light, easily digestible foods. Avoid spicy, oily, or very hot foods, as they can increase the burning sensation. Keep the anal area clean and dry to reduce irritation. If symptoms continue or worsen, consult a doctor for proper evaluation.

Have a query?

How Soon It Starts Working

The time required for Oflotas OZ Tablet to start to work: Oflotas OZ Tablet ideally shows its action within 1 to 3 hours after administration. The time for which the effects of Oflotas OZ Tablet last: The effect of Oflotas OZ Tablet lasts for 24 hours.

What if you forget to take Oflotas OZ Tablet

Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and follow your regular dosing schedule. Do not take a double dose to make up for your missed dose.

Storage

• Store Oflotas OZ Tablet tablets at room temperature, ideally between 20°C and 25°C (68°F to 77°F). • Keep the tablets in their original blister packaging to protect them from light and moisture.

Drug Warnings

Check Expiry Date: Always check the expiration date on the blister pack before taking your dose.
Avoid Driving or Machinery Use: Do not drive or operate machinery if you feel dizzy or lightheaded after taking this medicine.
Sun Protection: Protect your skin from direct sunlight, sunlamps, and tanning beds, as this medicine can make your skin highly sensitive to sunburn.
Avoid Certain Antacids and Supplements: Do not take antacids containing magnesium or aluminum, or supplements containing iron or zinc, within 2 hours of taking Oflotas OZ Tablet , as they can stop the medicine from working properly.
Seek Medical Attention: Stop taking the medicine immediately and call your doctor if you experience sudden pain or swelling in any of your joints.
Important Safety Warning (Fluoroquinolone Risk): Ofloxacin belongs to the fluoroquinolone class of antibiotics, which carries a regulatory warning for rare but serious side effects, including tendon inflammation or rupture, peripheral neuropathy (nerve damage causing tingling, burning, or numbness), and in some cases, worsening of muscle or nerve-related conditions. Stop the medicine immediately and contact your doctor if you develop sudden joint or tendon pain, numbness, or unusual nerve sensations.

Drug-Drug Interactions

Drug-Drug Interactions

The following medicines may interact with Oflotas OZ Tablet and affect its safety or effectiveness:

Blood thinners (like warfarin): Combining these can significantly increase your risk of bleeding.
Antacids and mineral supplements: Products containing magnesium, aluminum, calcium, iron, or zinc can block the absorption of Oflotas OZ Tablet , reducing its effectiveness.
Medicines affecting heart rhythm: Taking this medicine alongside other drugs known to affect the heart's electrical activity can increase the risk of irregular heartbeats.
Pain relievers (NSAIDs): Using certain pain relievers alongside Oflotas OZ Tablet can increase the risk of central nervous system side effects, including seizures.

Drug-Food Interactions

Certain foods and beverages may interfere with how Oflotas OZ Tablet works in your body:

Dairy Products (Milk, Yoghurt, Cheese): The main concern is with high-calcium products such as antacids or calcium supplements, which can significantly reduce absorption of ofloxacin. Normal dietary amounts of dairy are generally not clinically significant. However, to be cautious, it is advisable to maintain a 2-hour gap between Oflotas OZ Tablet and high-calcium supplements or antacid products.
Caffeine: This medicine can slow down how your body processes caffeine, leading to increased jitteriness, anxiety, or a rapid heart rate.

Drug-Disease Interactions

Certain medical conditions may affect how Oflotas OZ Tablet works or increase the risk of side effects:

Nerve disorders: May worsen existing symptoms of peripheral neuropathy (numbness or tingling).
Tendon disorders: Increases the risk of tendonitis or tendon rupture, especially in older adults.
Kidney or liver damage: May require your doctor to adjust your dose to prevent the medicine from building up to unsafe levels in your body.
Epilepsy: May lower the seizure threshold, making seizures more likely.

Ornidazole + OfloxacinZiprasidone

Critical

Ornidazole + OfloxacinDisopyramide

Critical

Drug-Drug Interactions

Ornidazole + OfloxacinZiprasidone

Critical

How does the drug interact with Oflotas OZ Tablet:
Co-administration of Oflotas OZ Tablet with Ziprasidone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Oflotas OZ Tablet with Ziprasidone together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or chest pain, ontact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Ornidazole + OfloxacinDisopyramide

Critical

How does the drug interact with Oflotas OZ Tablet:
Co-administration of Oflotas OZ Tablet with Disopyramide can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Oflotas OZ Tablet with Disopyramide together is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Ornidazole + OfloxacinAmiodarone

Critical

How does the drug interact with Oflotas OZ Tablet:
The combination of Amiodarone and Oflotas OZ Tablet may significantly increase the risk of an abnormal heart rhythm.

How to manage the interaction:
Although Amiodarone and inOrnidazole + Ofloxacin teract, it can be taken if prescribed by a doctor. If you get dizziness, lightheadedness, fainting, or fast or racing heartbeats, consult a doctor. Do not stop taking any medications without consulting a doctor.

Ornidazole + OfloxacinCisapride

Critical

How does the drug interact with Oflotas OZ Tablet:
Co-administration of Oflotas OZ Tablet with Cisapride can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Oflotas OZ Tablet with Cisapride together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor. Note: Cisapride is no longer available on the market. Cisapride should only be taken if prescribed by a doctor and closely monitored.

Ornidazole + OfloxacinSotalol

Critical

How does the drug interact with Oflotas OZ Tablet:
Co-administration of Oflotas OZ Tablet with Sotalol can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Oflotas OZ Tablet with Sotalol together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. If you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain, or tightness, contact a doctor. Do not discontinue any medications without consulting a doctor.

Ornidazole + OfloxacinSaquinavir

Critical

How does the drug interact with Oflotas OZ Tablet:
Co-administration of Oflotas OZ Tablet with Saquinavir can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Oflotas OZ Tablet with Saquinavir together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or chest pain, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Ornidazole + OfloxacinMesoridazine

Critical

How does the drug interact with Oflotas OZ Tablet:
Using Mesoridazine together with Oflotas OZ Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Mesoridazine with Oflotas OZ Tablet is not recommended, please consult a doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.

Ornidazole + OfloxacinPimozide

Critical

How does the drug interact with Oflotas OZ Tablet:
Co-administration of Oflotas OZ Tablet with Pimozide can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Oflotas OZ Tablet with Pimozide together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or chest pain, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Ornidazole + OfloxacinQuinidine

Critical

How does the drug interact with Oflotas OZ Tablet:
Co-administration of Oflotas OZ Tablet with Quinidine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Oflotas OZ Tablet with Quinidine together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or chest pain, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Ornidazole + OfloxacinBepridil

Critical

How does the drug interact with Oflotas OZ Tablet:
Using Bepridil together with Oflotas OZ Tablet drugs can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Oflotas OZ Tablet with Bepridil can cause an interaction, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Habit Forming

Therapeutic Class

[ANTIBIOTICS]

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Author Details

Written By

Santoshini Reddy G
M Pharmacy

Reviewed By

Veda Maddala
M Pharmacy

Last Updated

Jun 26, 2026 | 1:24 PM IST

We provide you with authentic, trustworthy and relevant information.

See our editorial policy

Reference

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Other Info - OFL0076

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Oflotas OZ Tablet 10's

Delivery Information

More about the Product

Composition :

Manufacturer/Marketer :

Consume Type :

Expires on or after :

Return Policy :

About Oflotas OZ Tablet

Uses of Oflotas OZ Tablet

Key Benefits

Nausea

Trouble Falling/ Staying Asleep

Headache

Dizziness

Loose And Watery Stools

Vomiting

Less Hunger

Directions for Use

How Oflotas OZ Tablet Works

Alcohol

Pregnancy

Breast Feeding

Driving

Liver

Kidney

Children

Heart

Geriatrics

What if I have taken an overdose of Oflotas OZ Tablet

Diet & Lifestyle Advise

Health Queries

I am suffering from severe fever with chills and frequent loose motions. How should it be treated?

For the past few days, I have had frequent motions and feel a burning sensation when passing stools. What should I do?

How Soon It Starts Working

What if you forget to take Oflotas OZ Tablet

Storage

Drug Warnings

Drug-Drug Interactions

Drug-Drug Interactions

Drug-Food Interactions

Drug-Food Interactions

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What is the use of Oflotas OZ Tablet ?

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Does Oflotas OZ Tablet cause drowsiness?

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Can I take Oflotas OZ Tablet with dairy products?

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