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OFM-DS Suspension is an antibiotic medicine used to treat bacterial infections in children. It contains Ofloxacin and Metronidazole. Ofloxacin works by inhibiting the repair of the bacterial cell wall (a protective covering) and causing damage to the bacterial cell wall. This eventually leads to the death of the bacterial cell and thus prevents the growth of bacterial infections. Metronidazole kills parasites and anaerobic bacteria that are responsible for causing infections. It works by damaging their DNA.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Lekar Pharma Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About OFM-DS Suspension

OFM-DS Suspension is a suspension prescribed to treat mixed bacterial and parasitic stomach infections in children. It is commonly used to manage infectious diarrhoea, dysentery, and other gastrointestinal tract infections. By targeting two different types of disease-causing organisms in the gut, it helps restore your child’s digestive health.
To ensure the infection is completely cleared, this medicine must be taken consistently at the exact times prescribed by your doctor. It is usually taken twice daily and is best given with food to prevent any stomach upset. Alongside this medicine, keeping your child hydrated with oral rehydration solutions and serving light, easily digestible meals will support their recovery.
While using this medicine, your child might experience mild side effects like a temporary metallic taste, nausea, or a slight loss of appetite. However, if you notice serious signs such as a severe skin rash, yellowing of the eyes, or extreme dizziness, stop the medicine and contact your doctor immediately.
Before starting your child on this medicine, inform your doctor if they have any pre-existing liver issues, kidney problems, or a history of tendon pain. Children who are allergic to either of the active ingredients or similar medicines must not take this suspension.
Do not give this medicine at the same time as dairy products, calcium-fortified juices, or antacids, as they can prevent the medicine from being absorbed properly. Always consult your paediatrician before combining this medicine with any other prescription or over-the-counter medications.

Uses of OFM-DS Suspension

Your doctor may prescribe OFM-DS Suspension to help manage the following conditions:

  • Infectious Diarrhoea and Dysentery: It stops the growth of both bacteria and amoebae in the gut, quickly reducing loose stools and stomach pain.
  • Gastrointestinal Infections: It targets harmful microorganisms in the digestive tract, clearing up infections that cause bloating, cramps, and fever.

Key Benefits

When used as directed as part of your treatment plan, OFM-DS Suspension may provide the following benefits:

  • Rapid Relief from Stomach Discomfort: By quickly clearing the infection-causing germs, OFM-DS Suspension reduces painful abdominal cramps and stomach spasms, letting your child rest comfortably.
  • Prevents Severe Dehydration: By stopping frequent loose stools and vomiting, this medicine helps your child retain vital fluids and nutrients, speeding up their return to play and daily activities.
  • Dual-Action Coverage: Because it fights both bacteria and parasites simultaneously, it ensures that mixed infections are thoroughly treated without the need for multiple separate medications.
Side effects of OFM-DS Suspension 60 ml
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
  • Manage stress by practising deep breathing, yoga or meditation.
  • Participating in activities you enjoy, or exercising may also help manage agitation.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Exercise regularly. Try physical activities like walking, running, or dancing.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
  • Eat a balanced diet rich in fruits, vegetables, and whole grains to support overall health.
  • Include foods high in omega-3 fatty acids, like salmon and walnuts, to support eye health.
  • Stay hydrated by drinking plenty of water.
  • Engage in regular physical activity, like walking or yoga, to improve mobility and balance.
  • Practice stress-reducing techniques, like meditation or deep breathing, to manage emotional challenges.
  • Establish a daily routine to maintain independence and organization.
  • Consider learning Braille or using assistive technologies to enhance daily life.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.
  • To the affected part, apply warm compresses to get a temporary relief.
  • Rinse your eye carefully with clean water and try to blow any dust particle that could have entered.
  • Take over the counter medication to lubricate your eye or if there is pain due to allergy to soothe the eye.
  • If there is persistent pain in your eye, consult your doctor and follow the medication immediately.

Directions for Use

  • OFM-DS Suspension can be administered with or without food as directed by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Administer the prescribed dose to the child using the measuring cup/dosing syringe.
  • Shake well before use.

How OFM-DS Suspension Works

OFM-DS Suspension contains Ofloxacin and Metronidazole, which work together to eliminate harmful bacteria and parasites. Ofloxacin is an antibiotic that works by blocking a vital enzyme that bacteria need to repair and copy their DNA. Without this enzyme, the bacteria cannot multiply and quickly die off. Metronidazole is an antiprotozoal and antibacterial agent that enters the cells of parasites (like amoebae) and certain anaerobic bacteria. Once inside, it damages their DNA, stopping them from growing and causing further infection. Together, these two ingredients deliver a comprehensive shield, clearing out the digestive tract safely and effectively.
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Alcohol

Not applicable

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Pregnancy

Not applicable

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Breast Feeding

Not applicable

-

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Driving

Not applicable

-

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Liver

Caution

Please consult your doctor if your child has a liver impairment or if you have any concerns regarding this.

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Kidney

Caution

Please consult your doctor if your child has a kidney impairment or if you have any concerns regarding this.

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Children

Safe if prescribed

OFM-DS Suspension is safe for children if prescribed by the doctor. The dose of the medicine will be decided by your paediatrician. Do not give more than the recommended dose to your child.

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Heart

Caution

OFM-DS Suspension may rarely cause a serious heart rhythm issue (QT prolongation and torsades de pointes). Children with heart conditions or on certain medications may be at higher risk. Consult a pediatrician before use.

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Geriatrics

Not applicable

OFM-DS Suspension is for paediatric patients only.

What if I have taken an overdose of OFM-DS Suspension

If you suspect your child has taken more than the prescribed dose of OFM-DS Suspension, seek immediate medical attention.

Diet & Lifestyle Advise

  • Stay Hydrated: Keep your child well-hydrated by offering frequent, small sips of oral rehydration solutions (ORS), clear broths, or coconut water to replace lost salts and fluids.
  • Eat Gentle Foods: Serve simple, bland foods that are easy on the stomach, such as bananas, rice, applesauce, and toast, while avoiding spicy, oily, or greasy meals.
  • Keep Hands Clean: Practice strict hand hygiene by washing your hands and your child’s hands thoroughly with soap and water before meals and after using the bathroom to prevent reinfection.
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How Soon It Starts Working

The time required for OFM-DS Suspension to start to work: The onset time of OFM-DS Suspension has not been clinically established. The time for which the effects of OFM-DS Suspension last: The duration of OFM-DS Suspension’s effect is clinically not established.

What if you forget to take OFM-DS Suspension

If you forget to give a dose, give it as soon as you remember. However, if it is almost time for the next scheduled dose, skip the missed one and continue with the regular schedule. Never give a double dose to make up for a missed one.

Storage

• Store OFM-DS Suspension at room temperature, safely between 15°C and 30°C (59°F to 86°F).

Drug Warnings

  • Shake Well: Always shake the bottle vigorously before each dose to make sure the ingredients are properly mixed.
  • Do Not Share: Never give this medicine to other children, even if they have the same symptoms.
  • Watch for Tendon Pain: Monitor your child for joint swelling or tendon pain, especially in older, active children. Stop the medicine and call your doctor if this happens.
  • Check Before Use: Do not use the medicine if it looks discoloured, contains clumps, or has leaked from the bottle.
  • Finish the Course: Always complete the full treatment prescribed by your doctor, even if your child feels better, to prevent the infection from returning.

Drug-Drug Interactions

verifiedApollotooltip
  • Antacids and Multivitamins: Giving medicines containing iron, zinc, calcium, or magnesium at the same time can significantly decrease the absorption of OFM-DS Suspension.
  • Blood Thinners: May increase the effects of blood-thinning medications, raising the risk of bleeding.
  • Seizure Medications: Certain anti-seizure drugs can speed up how the body processes OFM-DS Suspension, making it less effective.
Critical

Drug-Drug Interactions

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Critical
How does the drug interact with OFM-DS Suspension 60 ml:
Using halofantrine together with ofloxacin and Metronidazole can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Ofloxacin and Metronidazole with Halofantrine can cause an interaction, please consult a doctor before taking it. You should seek immediate medical attention if you develop dizziness, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
How does the drug interact with OFM-DS Suspension 60 ml:
Taking Amiodarone with Ofloxacin and Metronidazole may significantly increase the risk of an abnormal heart rhythm.

How to manage the interaction:
Although Amiodarone with Ofloxacin and Metronidazole interact, it can be taken if prescribed by a doctor. If you get dizziness, or fast or racing heartbeats, consult a doctor. Do not stop taking any medications without consulting a doctor.
Critical
How does the drug interact with OFM-DS Suspension 60 ml:
Co-administration of Amprenavir with Ofloxacin and Metronidazole can increase the risk or severity of side effects.

How to manage the interaction:
Taking Ofloxacin and Metronidazole with Amprenavir is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience throbbing in the head and neck, difficulty breathing, vomiting, chest pain, rapid heartbeat, palpitation, low blood pressure, dizziness contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with OFM-DS Suspension 60 ml:
Coadministration of Ofloxacin and Metronidazole with Cisapride can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Ofloxacin Metronidazole with Cisapride together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience dizziness, shortness of breath, chest pain, rapid heartbeat contact a doctor immediately. Do not discontinue any medications without consulting a doctor. Note: Cisapride is no longer available on the market.
How does the drug interact with OFM-DS Suspension 60 ml:
Coadministration of Citalopram together with Ofloxacin and Metronidazole may raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Even though Ofloxacin and Metronidazole with Citalopram interact, they can be used if prescribed by a doctor. Consult a doctor if you have dizziness, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
How does the drug interact with OFM-DS Suspension 60 ml:
Coadministration of Dolasetron with ofloxacin and Metronidazole may increase the risk of an abnormal heart rhythm.

How to manage the interaction:
Although Ofloxacin and Metronidazole with Dolasetron interact, they can be used if prescribed by a doctor. Consult a doctor if you have dizziness, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
How does the drug interact with OFM-DS Suspension 60 ml:
Coadministration of Ofloxacin and Metronidazole with Papaverine can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Ofloxacin and Metronidazole with Papaverine together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience dizziness, shortness of breath, chest pain, rapid heartbeat contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with OFM-DS Suspension 60 ml:
Coadministration of Chloroquine together with ofloxacin and Metronidazole may raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Although Ofloxacin and Metronidazole with Chloroquine interact, they can be used if prescribed by a doctor. Consult a doctor if you have dizziness, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
How does the drug interact with OFM-DS Suspension 60 ml:
Coadministration of Ribociclib together with ofloxacin and Metronidazole may raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Although Ofloxacin and Metronidazole with Ribociclib interact, they can be used if prescribed by a doctor. Consult a doctor if you have dizziness, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
How does the drug interact with OFM-DS Suspension 60 ml:
Coadministration of Ofloxacin and Metronidazole with Vandetanib can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Ofloxacin and Metronidazole with Vandetanib together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience dizziness, shortness of breath, chest pain, rapid heartbeat contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Dairy and Calcium-Rich Foods: Milk, yoghurt, or calcium-fortified juices can bind to the medicine in the gut and prevent it from being absorbed properly. Give these foods at least 2 hours before or after the medicine.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

OFM-DS Suspension is used to treat Bacterial Infections and Amoebic dysentry.
OFM-DS Suspension is a combination medicine containing Ofloxacin (fluoroquinolone) and Metronidazole. Ofloxacin works by inhibiting the repair of the bacterial cell wall (a protective covering) and causing damage to the bacterial cell wall. This e Metronidazole kills parasites and anaerobic bacteria that are responsible for causing infections. It works by damaging their DNA.
OFM-DS Suspension can cause diarrhea in children. OFM-DS Suspension is an antibiotic that kills toxic bacteria, but it can also affect the useful bacteria in your intestine or stomach and lead to diarrhea. If your child experience diarrhea that is watery or bloody, call your doctor. Do not use anti-diarrheal medicine unless your paediatrician suggests it.
Let the doctor know if the child has liver problems, blood issues, a low white blood cell count (leukopenia), or nervous system conditions (such as convulsions). Taking OFM-DS Suspension may also increase the risk of developing tendinitis (swelling of the tissue that connects bone to muscle) or tendon rupture. Dairy products should be avoided while using OFM-DS Suspension, and you should limit exposure to sunlight, as it may increase the risk of phototoxicity or photosensitivity.
OFM-DS Suspension can be useful in treating loose motions if the cause is a bacterial or parasitic infection. However, it is not recommended for all cases of diarrhoea, as it may not be effective for viral infections or non-infectious causes. Please consult your doctor for proper diagnosis and treatment.
If your child develops a rash after taking OFM-DS Suspension, it could be a sign of an allergic reaction or a side effect. Discontinue the medication right away and contact your doctor to discuss what to do next and get the right treatment.
Yes, OFM-DS Suspension is an antibiotic that combines two medicines: ofloxacin and metronidazole. Ofloxacin targets bacterial DNA replication, while metronidazole is effective against anaerobic bacteria and certain parasites. Both are bactericidal in nature, and collectively they help treat the infection effectively.
If you accidentally give an excess dose of OFM-DS Suspension, monitor for potential side effects such as nausea, vomiting, stomach upset, loss of appetite, dry mouth, and a metallic taste. Contact your doctor immediately, as taking too much of the antibiotic may lead to adverse reactions.
If your child shows no improvement even after completing the prescribed course of OFM-DS Suspension, please consult your doctor. Also, inform the doctor if the symptoms are getting worse while using OFM-DS Suspension.
To prevent any interactions, it is advised to consult the doctor before using other medicines with OFM-DS Suspension. Inform the doctor if the child is taking anti-arrhythmics (quinidine, hydroquinidine, disopyramide, amiodarone, sotalol, dofetilide, ibutilide), tricyclic antidepressants, (clomipramine, amitriptyline), antipsychotics, or antimicrobials (erythromycin, clarithromycin, azithromycin).
Though OFM-DS Suspension may not interact with vaccines, it is advised to consult the doctor before receiving vaccination. Let the doctor know if your child is due to undergo vaccination while on treatment with OFM-DS Suspension.
Before giving OFM-DS Suspension to your child, tell the doctor if your child has any allergies, especially to any of its ingredients, or to other antibacterial or anti-amoebic medicines. You should inform the doctor if your child has any existing medical conditions, such as liver or kidney problems, low white blood cell count (leukopenia), or muscle spasms (convulsions). Also, let the doctor know if your child is taking any other medications to prevent potential interactions.
Yes. OFM-DS Suspension contains metronidazole, which may cause the urine to appear dark or reddish-brown. This is a common and harmless side effect that usually disappears after the treatment is completed. However, contact your doctor if the urine is very dark, contains blood, or if your child has pain while passing urine.
The common side effects of OFM-DS Suspension include nausea, vomiting, stomach pain, headache, and dizziness. If these side effects persist or worsen, please consult your doctor.
If you forget to give OFM-DS Suspension to your child, give the missed dose as soon as you remember, unless it is almost time for the next dose. If that is the case, skip the missed dose and give the next dose at the usual time. Never give two doses at once to make up for a missed dose.
Yes, OFM-DS Suspension is a broad-spectrum antibiotic that can treat a variety of infections in different parts of the body. It is effective against infections in areas such as the gastrointestinal tract, lungs, blood, heart, skin, bones, joints, and nervous system.
No, you should avoid giving this medicine with milk or other dairy products, as calcium can prevent the medicine from being absorbed properly. It is best given with water or a light, dairy-free meal. Talk to your doctor or paediatrician if you have questions about your child's diet during treatment.
Do not repeat the dose without medical advice if your child vomits after taking OFM-DS Suspension. Some of the medicine may already have been absorbed, and giving another dose could result in too much medicine. Contact your doctor or pharmacist before giving the dose again, as advice may depend on how soon the vomiting occurred and your child’s individual treatment plan.
It must be used with extreme caution in children with a history of seizures or nerve disorders, as it can potentially trigger or worsen these issues. Always discuss your child's full medical history with your paediatrician before starting this medicine. Talk to your doctor for safe alternatives if needed.
No. Even if your child feels better, continue giving OFM-DS Suspension for the full prescribed course. Stopping treatment early may allow bacteria or parasites to survive, causing the infection to return and increasing the risk of antibiotic resistance. Speak to your doctor if side effects are making it difficult to continue treatment.
No. OFM-DS Suspension treats bacterial and certain parasitic infections and is not effective against viral illnesses such as the common cold or flu. If your child has a cold and is taking cough or cold medicines, consult your doctor before giving them together to ensure they are appropriate and safe.

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Country of origin

INDIA

Manufacturer/Marketer address

SHETH GOVINDRAO SMRITI 83 B&CDR A B ROAD WORLI MUMBAI MH 400018 INDIA
Other Info - OFM0008
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