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compositionComposition:CHLORTHALIDONE-12.5MG+OLMESARTAN MEDOXOMIL-40MG
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Prescription Medicine
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Olmibid CT-40/12.5mg Tablet is used to treat high blood pressure. It contains Olmesartan medoxomil and Chlorthalidone, which work by relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently. Also, it removes extra water and certain electrolytes from the body. Together it lowers fluid overload, blood pressure and improves blood flow. In some cases, you may experience side effects such as headache, nausea, or dizziness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CHLORTHALIDONE-12.5MG+OLMESARTAN MEDOXOMIL-40MG

Manufacturer/Marketer :

Eswar Therapeutics Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Olmibid CT-40/12.5mg Tablet

Olmibid CT-40/12.5mg Tablet is a prescription tablet used to treat high blood pressure (hypertension). It works to lower blood pressure, which helps reduce the risk of serious cardiovascular events such as strokes and heart attacks. This medicine is typically prescribed when a single medication is not enough to control your blood pressure.

For the best results, you must take Olmibid CT-40/12.5mg Tablet consistently every single day, exactly as directed by your doctor. You can take this tablet with or without food, but taking it at the same time each day helps maintain steady levels of the medicine in your body. Incorporating a low-sodium diet and regular physical activity will also support your treatment.

While taking Olmibid CT-40/12.5mg Tablet , you may experience some mild side effects, such as dizziness or a lightheaded feeling. Most people tolerate this medication well, but you must contact your doctor immediately if you notice signs of severe dehydration, muscle weakness, or a sudden change in how much you urinate.

Do not take this if you are pregnant, as it can cause serious harm or death to an unborn baby. You should also talk to your doctor before starting Olmibid CT-40/12.5mg Tablet if you have severe kidney disease, liver damage, gout, or diabetes.

This medication can interact with other drugs, including pain relievers like ibuprofen, which can put extra strain on your kidneys. It is also important to limit alcohol while taking Olmibid CT-40/12.5mg Tablet because alcohol can worsen dizziness. Always consult your doctor if you are breastfeeding or are an older adult, as your body may require closer monitoring.

Uses of Olmibid CT-40/12.5mg Tablet

Olmibid CT-40/12.5mg Tablet is used to treat high blood pressure and help reduce the risk of cardiovascular complications associated with hypertension. The detailed uses of Olmibid CT-40/12.5mg Tablet are as follows: 

  • Hypertension (High Blood Pressure): Olmibid CT-40/12.5mg Tablet helps by relaxing blood vessels and reducing extra fluid in the body, which lowers overall blood pressure and protects your heart and organs from long-term damage.
     

Key Benefits

Lowering high blood pressure does not usually make you feel different immediately, but the long-term health benefits of taking Olmibid CT-40/12.5mg Tablet are substantial. By keeping your blood pressure within a healthy range, this medication helps protect you from silent, life-threatening complications.

  • Reduces Stroke and Heart Attack Risk: Consistently controlled blood pressure significantly lowers the strain on your heart and the blood vessels in your brain.
  • Convenient Dual Action: By combining two distinct blood pressure control methods into a single daily tablet, it simplifies your routine and reduces the number of pills you need to take.
  • Protects Kidneys and Blood Vessels: Long-term blood pressure control helps prevent permanent damage to your vital organs.
     

Directions for Use

Always take Olmibid CT-40/12.5mg Tablet exactly as prescribed by your doctor. Follow these simple guidelines to ensure you take it safely and effectively:

  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet.
  • You can take this medicine with or without food.
  • Try to take your dose at the same time every day, preferably in the morning, to prevent having to wake up during the night to urinate.
  • Keep taking this medication even if you feel well, as high blood pressure often has no noticeable symptoms.

Never adjust your dose or stop taking this medication without consulting your doctor first.
 

How Olmibid CT-40/12.5mg Tablet Works

Olmibid CT-40/12.5mg Tablet contains two active ingredients that work together through different mechanisms to lower blood pressure more effectively than either medicine alone. The first ingredient, olmesartan medoxomil, belongs to a group of medicines called angiotensin II receptor blockers (ARBs). It works by blocking the action of angiotensin II, a natural substance that causes blood vessels to tighten and narrow. By preventing this effect, olmesartan helps blood vessels relax and widen, allowing blood to flow more easily and reducing blood pressure. The second ingredient, chlorthalidone, is a thiazide-like diuretic, often called a 'water pill.' It helps the kidneys remove excess salt and water from the body through urine. This reduces the amount of fluid circulating in the blood vessels, which helps lower blood pressure. Chlorthalidone also has a long duration of action, providing blood pressure control throughout the day. Together, these medicines help lower blood pressure, reduce strain on the heart and blood vessels, and decrease the risk of complications associated with hypertension.
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Olmibid CT-40/12.5mg Tablet to avoid unpleasant side-effects.

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Pregnancy

Unsafe

Olmibid CT-40/12.5mg Tablet should not be taken until prescribed. Olmibid CT-40/12.5mg Tablet is a Category C/D pregnancy drug which is considered unsafe for pregnant women. Olmibid CT-40/12.5mg Tablet can have some harmful effects on the baby (foetus), Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

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Breast Feeding

Unsafe

Olmibid CT-40/12.5mg Tablet is not recommended in breastfeeding mothers. It is excreted into milk in small amounts and is cleared slowly. It can accumulate in the infant, especially newborns or preterm infants. Lactation might also be suppressed due to the effect of Olmibid CT-40/12.5mg Tablet .

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Driving

Unsafe

It is not recommended to drive after taking Olmibid CT-40/12.5mg Tablet as it may occasionally cause drowsiness or fatigue.

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Liver

Caution

Olmibid CT-40/12.5mg Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Olmibid CT-40/12.5mg Tablet to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Use of Olmibid CT-40/12.5mg Tablet in children less than 1 year of age is not recommended as the safety and efficacy of Olmibid CT-40/12.5mg Tablet in these age groups have not yet been established.

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Heart

Caution

Olmibid CT-40/12.5mg Tablet is often prescribed to patients with heart problems to treat hypertension. However, it must be taken strictly under medical supervision, as it can affect liver and kidney function and may interact with other heart medications.

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Geriatrics

Caution

Olmibid CT-40/12.5mg Tablet should be taken with caution in geriatric patients. Please inform your doctor before using Olmibid CT-40/12.5mg Tablet .

What if I have taken an overdose of Olmibid CT-40/12.5mg Tablet

Do not take more than the prescribed dose of Olmibid CT-40/12.5mg Tablet as it may cause serious side effects. If you suspect you have taken overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Reduce Sodium Intake: Limit salt in your meals and avoid processed foods, as sodium causes your body to hold onto extra fluid, raising blood pressure.
  • Stay Hydrated, but Moderately: Drink a healthy amount of fluids, but check with your doctor if you have kidney or heart issues.
  • Limit Potassium Substitutes: Since this medicine can affect potassium levels in your blood, avoid using salt substitutes that contain potassium without talking to your doctor.
  • Move Safely: Stand up slowly from sitting or lying positions to avoid sudden drops in blood pressure that can cause dizziness.
  • Maintain Regular Exercise: Gentle cardiovascular exercises like walking can help strengthen your heart and lower blood pressure naturally.
     
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How Soon It Starts Working

  • The time required for Olmibid CT-40/12.5mg Tablet to start to work: The time required for Olmibid CT-40/12.5mg Tablet to show its action is unknown.
  • The time for which the effects of Olmibid CT-40/12.5mg Tablet last: The effect of Olmibid CT-40/12.5mg Tablet lasts for 24 hours.

What if you forget to take Olmibid CT-40/12.5mg Tablet

Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and follow your regular dosing schedule. Do not take a double dose to make up for your missed dose.

Storage

Store Olmibid CT-40/12.5mg Tablet tablets at controlled room temperature, ideally between 20°C and 25°C (68°F to 77°F). • Keep the tablets in their original packaging to protect them from moisture and direct light.

Drug Warnings

  • Pregnancy Warning: Stop taking Olmibid CT-40/12.5mg Tablet immediately and contact your doctor if you discover you are pregnant, as it can cause serious injury or death to a developing fetus.
  • Watch for Dehydration: Excessive sweating, vomiting, or diarrhoea can cause a severe drop in blood pressure and lead to kidney complications.
  • Avoid NSAIDs: Consult your pharmacist before taking over-the-counter pain relievers like ibuprofen or naproxen, as they can reduce the blood-pressure-lowering effects of Olmibid CT-40/12.5mg Tablet and strain your kidneys.
  • Monitor Electrolytes: Keep all appointments for blood tests so your doctor can check your kidney health and potassium levels.
  • Be Careful Driving: This medicine can make you feel dizzy or tired, especially when you first start taking it. Avoid driving or operating machinery until you know how it affects you.
     

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Drug-Drug Interactions

Inform your doctor if you are taking any of the following medicines, as they may interact with Olmibid CT-40/12.5mg Tablet :

  • Lithium: Taking Olmibid CT-40/12.5mg Tablet with lithium can increase lithium levels in your blood, raising the risk of severe lithium toxicity.
  • NSAIDs (like ibuprofen or naproxen): These pain relievers can lower the effectiveness of your blood pressure medicine and increase the risk of acute kidney injury.
  • Other Blood Pressure Medicines: Combining Olmibid CT-40/12.5mg Tablet with other blood pressure medicines, particularly aliskiren in patients with diabetes, may increase the risk of very low blood pressure, kidney problems, and changes in potassium levels. Because olmesartan may increase potassium while chlorthalidone may lower it, regular monitoring of electrolyte levels may be required.

Drug-Food Interactions

The following foods and beverages may interact with Olmibid CT-40/12.5mg Tablet and affect its safety or effectiveness:

  • Potassium Supplements and Salt Substitutes: Using these while taking Olmibid CT-40/12.5mg Tablet can cause potassium to build up to dangerous levels in your blood.
  • Alcohol: Drinking alcohol can increase the blood-pressure-lowering effect, making you more prone to dizziness, fainting, or drowsiness.

Drug-Disease Interactions

Inform your doctor if you have a history of the following conditions before taking Olmibid CT-40/12.5mg Tablet , as it may worsen your condition or cause complications:

  • Severe Kidney Disease or Anuria: Do not take this medicine if your kidneys are not producing urine, as it can worsen kidney failure.
  • Gout: The water pill component of this medicine can increase uric acid levels, which may trigger or worsen gout attacks.
  • Diabetes: This medication may alter blood glucose levels, meaning your diabetes treatment might need adjustment.
     

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Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

FAQs

Olmibid CT-40/12.5mg Tablet is used to treat high blood pressure. It works by relaxing blood vessels, this allows the blood to flow more smoothly and the heart to pump more efficiently. Olmibid CT-40/12.5mg Tablet also removes extra water and certain electrolytes from the body. Thereby, it lowers fluid overload and blood pressure.
Taking Olmibid CT-40/12.5mg Tablet may cause dehydration. So, to avoid dehydration, drink plenty of fluids and inform your doctor if you feel extremely thirsty.
It's unlikely that Olmibid CT-40/12.5mg Tablet affects fertility in men or women. However, some water pills like hydrochlorothiazide may lead to erectile dysfunction. There's not enough evidence to say for certain. For best advise, consult your doctor.
Olmibid CT-40/12.5mg Tablet can be safely taken as long as your doctor has prescribed it to you. Conditions such as high blood pressure are life-long conditions and one should not abruptly discontinue it without discussing it with a doctor.
Olmibid CT-40/12.5mg Tablet is a combination of two medicines namely: Olmesartan medoxomil and Chlorthalidone. Olmesartan medoxomil is an angiotensin receptor blocker (ARB) that works by blocking the hormone angiotensin, thereby relaxing blood vessels. Chlorthalidone is a diuretic or water pill that removes extra water and certain electrolytes from the body. Together they lower fluid overload, blood pressure and improve blood flow.
You can take Olmibid CT-40/12.5mg Tablet at any time of day, but it's preferable to take it in the morning. Consistency is key, so try to take it at the same time every day. Most importantly, follow your doctor's instructions and take Olmibid CT-40/12.5mg Tablet exactly as directed.
Taking Olmibid CT-40/12.5mg Tablet can cause dizziness in some people. This is usually mild and temporary. To minimize this risk, take Olmibid CT-40/12.5mg Tablet as directed, get up slowly, and avoid standing for long periods. If you experience severe or persistent dizziness, contact your doctor. Always consult your doctor if you have concerns about side effects or taking Olmibid CT-40/12.5mg Tablet .
While using Olmibid CT-40/12.5mg Tablet , consider making lifestyle changes to help manage your blood pressure and overall health. Maintain a healthy weight, exercise for at least 30 minutes a day, and eat a balanced diet rich in whole grains, fruits, vegetables, and low-fat dairy products. Limit your sodium intake and alcohol consumption, and quit smoking if you haven't already. Manage stress through mindfulness practices and social support, and monitor your blood pressure daily. Additionally, include omega-3 rich foods in your diet and use low-fat oils like olive, soybean, canola, and coconut oil for cooking. Remember to consult your doctor for personalized advice on making these lifestyle changes to ensure you're taking the best care of your health.
Olmibid CT-40/12.5mg Tablet is not typically associated with weight gain and does not significantly affect body weight. However, it's important to remember that individual results may vary. If you have specific concerns or questions, it's always best to consult with your healthcare provider for personalized guidance and care.
Although rare, Olmibid CT-40/12.5mg Tablet may cause serious side effects in a few individuals. These severe reactions include swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs, as well as severe diarrhea, weight loss, difficulty breathing or swallowing, hoarseness, sore throat with fever, unusual bleeding or bruising, and severe skin rash with peeling skin. If you experience any of these symptoms, seek medical attention promptly. Your doctor will assess the risks and recommend the best course of action to relieve them.
Generally, Olmibid CT-40/12.5mg Tablet is considered safe for long-term use, as it is often prescribed to manage conditions like high blood pressure, which may require lifelong treatment. In fact, many people take Olmibid CT-40/12.5mg Tablet for extended periods to maintain healthy blood pressure and reduce the risk of cardiovascular complications as directed by the doctor. However, it's essential to regularly consult with your doctor to monitor your response to the medication, adjust dosages as needed, and minimize potential side effects.
Tell your doctor you're taking Olmibid CT-40/12.5mg Tablet before surgery. They may ask you to stop taking it for a while to ensure your safety. This is because Olmibid CT-40/12.5mg Tablet can lower blood pressure. Follow your doctor's advice to avoid any problems.
Common side effects of Olmibid CT-40/12.5mg Tablet include dizziness, bradycardia (slow heart rate), cold extremities, headache, hypotension (low blood pressure), and nausea. While these side effects may be uncomfortable, they often have a minimal impact and may subside over time. However, if your symptoms worsen or become severe, consult your doctor promptly. They will assess your situation and provide guidance on managing your side effects, which may include adjusting your treatment plan to minimize your discomfort.
No, you must not take Olmibid CT-40/12.5mg Tablet if you are pregnant. Taking it during pregnancy can cause severe harm or even death to the unborn baby. If you become pregnant while taking this medication, stop taking it immediately and contact your doctor.
Some people may notice a reduction in blood pressure within 1 to 2 weeks of starting treatment. However, the full blood-pressure-lowering effect may take several weeks and can continue to improve for up to 8 weeks with regular use. Continue taking the medicine exactly as prescribed and attend follow-up appointments so your doctor can monitor your progress. Talk to your doctor if your blood pressure remains high after a few weeks.
Severe muscle cramps can be a sign that the fluid and electrolyte levels in your body are off. You should contact your doctor right away to have your potassium and other blood levels checked.
No, high blood pressure usually has no outward symptoms, so you may feel perfectly fine even when your blood pressure is high. Stopping Olmibid CT-40/12.5mg Tablet suddenly can cause your blood pressure to spike. Always talk to your doctor before making any changes.
No, you should avoid salt substitutes containing potassium. This medicine can affect how your body handles potassium, and adding extra potassium can lead to dangerously high levels in your blood. Talk to your doctor or pharmacist for safe dietary advice.
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed one and continue with your normal schedule. Do not take two doses at once. Talk to your doctor or pharmacist if you frequently miss doses.
In some patients, particularly those with pre-existing kidney disease or severe dehydration, this medication can affect kidney function. Your doctor will likely monitor your kidneys through simple blood tests. Talk to your doctor if you experience sudden changes in urination.

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Reference

  1. Electronic Medicines Compendium (EMC). Product Summary of Product Characteristics (SmPC). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. Drugs.com Clinical Review Team. Olmesartan Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  3. Mayo Clinic Staff. Drg 20071817 Inhalation and Dosage Monograph. Rochester, MN: Mayo Foundation for Medical Education; 2025. [Accessed on 02 Jun. 2026]Check here
  4. Electronic Medicines Compendium (EMC). Pil.8787 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  5. Chlorthalidone [Prescribing Information]. 2019. [Accessed on 28th Sept. 2023]Check here
  6. Olmesartan Medoxomil [Package Insert Leaflet]. 2022. [Accessed on 28th Sept. 2023]Check here
  7. Olmesartan medoxomil 10 mg Film-coated tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. [Accessed on 24 Mar 2025]Check here

Country of origin

India

Manufacturer/Marketer address

203 & 204, Aspen, Kesar Garden, Sector -20, Navi Mumbai
Other Info - OLM0391
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