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  3. On N On 4mg Tablet

On N On 4mg Tablet, Pack of 1 Tablet
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Composition :

ONDANSETRON-4MG

Manufacturer/Marketer :

Aeon Pharma Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About On N On 4mg Tablet

On N On 4mg Tablet is an antiemetic medicine. It is used to prevent nausea and vomiting associated with moderately emetogenic cancer chemotherapy and radiotherapy in children. It is also used to treat nausea and vomiting caused by stomach problems and surgery. Nausea is an uneasy feeling in which a person feels an urge to vomit, while vomiting is the natural response to the body's forceful discharge of the stomach contents.

On N On 4mg Tablet contains 'Ondanestron' that belongs to serotonin 5-HT3 receptor antagonist. It works by blocking the action of a chemical called serotonin in the body, which is responsible for nausea and vomiting. As a result, On N On 4mg Tablet prevents the sensation of nausea and vomiting caused by cancer chemotherapy.

On N On 4mg Tablet may cause certain side effects in your child, such as feeling of warmth, headache, diarrhoea, and stomach pain. These side effects generally resolve over time. However, if it does not resolve, stop giving this medicine to your child and contact the paediatrician. Do not give more than the prescribed dose of On N On 4mg Tablet to the child. On N On 4mg Tablet can be given with or without food. Your paediatrician will decide the dose of the medicine.

On N On 4mg Tablet is intended for paediatric use only. Avoid giving On N On 4mg Tablet to your child if she/he is allergic to it. Keep your doctor informed about your child’s health condition, including his current medications and medical history, to rule out any side effects/interactions. Before administration, inform your child’s doctor if your child has liver and kidney problems.

Uses of On N On 4mg Tablet

On N On 4mg Tablet is used in the prevention of Nausea and Vomiting. The detailed uses of On N On 4mg Tablet are as follows:<br/>•Postoperative Nausea and Vomiting Relief: On N On 4mg Tablet is commonly used to alleviate nausea and vomiting experienced by patients after surgical procedures, often caused by anesthesia.<br/>•Supportive Care in Palliative Settings: On N On 4mg Tablet provides relief for nausea and vomiting in palliative care patients, helping to improve comfort amidst challenges from underlying conditions or treatment side effects.<br/>

Directions for Use

• On N On 4mg Tablet can be administered with or without food as directed by the doctor.• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Administer the prescribed dose to the child using the measuring cup/dosing syringe.• Shake well before use.

Medicinal Benefits

On N On 4mg Tablet contains 'Ondanestron' that belongs to serotonin 5-HT3 receptor antagonist. It works by blocking the action of a chemical called serotonin in the body, which is responsible for nausea and vomiting. As a result, On N On 4mg Tablet prevents the sensation of nausea and vomiting caused by cancer chemotherapy.

How On N On 4mg Tablet Works

On N On 4mg Tablet contains 'Ondanestron' that belongs to serotonin 5-HT3 receptor antagonist. It works by blocking the action of a chemical called serotonin in the body, which is responsible for nausea and vomiting. As a result, On N On 4mg Tablet prevents the sensation of nausea and vomiting caused by cancer chemotherapy.

Storage

Store in a cool and dry place away from sunlight
Side effects of On N On 4mg Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
  • Avoid rubbing or scratching the affected area, as this can cause further irritation and discomfort.
  • Consider using a humidifier to add moisture to the air and help reduce the sensation.
  • Seek medical attention if the sensation is severe, persistent, or worsens over time.
  • Avoid extreme temperatures, such as hot or cold showers, that can exacerbate the sensation.
  • Wear light, breathable clothing to help keep the body cool and reduce the sensation.
  • Avoid triggers that can cause the sensation, such as spicy foods or hot drinks.
  • Use cool compresses or fans to help lower body temperature and reduce the sensation.
Managing Medication-Triggered malaise (Feeling Unwell): A Step-by-Step Guide:
  • If you experience persistent or severe malaise (a general feeling of discomfort, illness, or unease) after taking medication, seek medical attention immediately.
  • Inform your doctor about the medication you're taking and the symptoms you're experiencing.
  • Your treatment plan may be modified, which may include adjusting the dosage, substituting with an alternative medication, or discontinuing the medication. Additionally, certain lifestyle changes may be recommended to help manage symptoms.
  • To manage malaise symptoms, follow your doctor's advice, such as getting plenty of rest, staying hydrated, and practicing stress-reducing techniques.
  • Track your symptoms regularly and report any changes or concerns to your healthcare provider to ensure the malaise is managed effectively.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

What if I have taken an overdose of On N On 4mg Tablet

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of On N On 4mg Tablet may include constipation, dizziness or lightheadedness, fainting, irregular heartbeat, and sudden loss of vision for a short time. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Avoid giving On N On 4mg Tablet to your child if he/she is allergic to it. Keep your doctor informed about your child’s health condition, including his current medications and medical history, to rule out any side effects/interactions. Before administration, inform your doctor if your child has liver and kidney disease. This medicine is intended for only the paediatric population. Hence, it is not recommended for use in special populations (pregnant and breastfeeding mothers) and adults.

Drug-Drug Interactions

verifiedApollotooltip
OndansetronZiprasidone
Critical
OndansetronAnagrelide
Severe

Drug-Drug Interactions

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OndansetronZiprasidone
Critical
How does the drug interact with On N On 4mg Tablet:
Taking On N On 4mg Tablet with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking On N On 4mg Tablet with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
OndansetronAnagrelide
Severe
How does the drug interact with On N On 4mg Tablet:
Taking On N On 4mg Tablet with anagrelide increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of On N On 4mg Tablet alongside anagrelide can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, get medical help immediately. Do not discontinue any medications without a doctor's advice.
OndansetronVilazodone
Severe
How does the drug interact with On N On 4mg Tablet:
When Vilazodone is taken with On N On 4mg Tablet, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in body).

How to manage the interaction:
There may be a possibility of interaction between Vilazodone and On N On 4mg Tablet, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea-call a doctor right away. Do not stop using any medications without a doctor's advice.
OndansetronTapentadol
Severe
How does the drug interact with On N On 4mg Tablet:
Using Tapentadol together with On N On 4mg Tablet might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Although taking On N On 4mg Tablet along with tapentadol can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.
OndansetronVortioxetine
Severe
How does the drug interact with On N On 4mg Tablet:
When On N On 4mg Tablet, is taken with Vortioxetine it can cause serotonin syndrome (A condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Co-administration of On N On 4mg Tablet along with Vortioxetine can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.
OndansetronFurazolidone
Severe
How does the drug interact with On N On 4mg Tablet:
When On N On 4mg Tablet, is taken with furazolidone it can cause serotonin syndrome. (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of On N On 4mg Tablet along with furazolidone can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.
OndansetronSumatriptan
Severe
How does the drug interact with On N On 4mg Tablet:
Using On N On 4mg Tablet together with Sumatriptan might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Co-administration of On N On 4mg Tablet along with sumatriptan can lead to an interaction, it should be taken only if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.
OndansetronIloperidone
Severe
How does the drug interact with On N On 4mg Tablet:
Taking On N On 4mg Tablet with Iloperidone increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of On N On 4mg Tablet along with Iloperidone can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
OndansetronSotalol
Severe
How does the drug interact with On N On 4mg Tablet:
Taking On N On 4mg Tablet and Sotalol can increase the risk or severity of irregular heart rhythms which can be severe.

How to manage the interaction:
Although taking On N On 4mg Tablet and Sotalol can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat consult a doctor. Do not discontinue any medications without a doctor's advice.
OndansetronParoxetine
Severe
How does the drug interact with On N On 4mg Tablet:
When On N On 4mg Tablet is taken with paroxetine, can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Co-administration of On N On 4mg Tablet along with paroxetine can result in an interaction, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea, or fast or rapid heartbeats during therapy, consult the doctor. Do not stop using any medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Certain food items/medicines are known to cause nausea/vomiting to your child.
  • Make your child drink more fluids to avoid dehydration.
  • Providing your child with a healthy diet that includes lots of fruits and vegetables, nuts, and low-fat dairy products will help keep your child in good health and avoid chances of nausea and vomiting. 
  • Avoid giving greasy or oily foods to your child, as this food triggers nausea and vomiting.

Habit Forming

No

Therapeutic Class

ANTIEMETICS

On N On 4mg Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Not applicable

-

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Pregnancy

Not applicable

-

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Breast Feeding

Not applicable

-

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Driving

Not applicable

-

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Liver

Caution

Please consult your doctor if your child has a liver impairment or if you have any concerns regarding this. Your paediatrician will weigh the benefits and risks before prescribing On N On 4mg Tablet to your child.

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Kidney

Caution

Please consult your doctor if your child has a kidney impairment or if you have any concerns regarding this. Your paediatrician will weigh the benefits and risks before prescribing On N On 4mg Tablet to your child.

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Children

Safe if prescribed

On N On 4mg Tablet is safe for children above 4 years of age if prescribed by the doctor. The dose of the medicine will be decided by your paediatrician. Do not give more than the recommended dose to your child.

Have a query?

FAQs

On N On 4mg Tablet is used to treat vomiting.

On N On 4mg Tablet contains Ondanestron; that belongs to serotonin 5-HT3 receptor antagonist. It works by blocking the action of a chemical called serotonin in the body which is responsible for causing nausea and vomiting.

Use On N On 4mg Tablet for as long as your paediatrician suggested.

Country of origin

India
Other Info - ON78831

Disclaimer

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Author Details

Veda MaddalaDoctor badge

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Jul 18, 2025 | 7:04 AM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/020103s035_020605s019_020781s019lbl.pdf
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