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compositionComposition:DAPAGLIFLOZIN-10MG+LINAGLIPTIN-5MG
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Ondero-D 10 Tablet is an antidiabetic medicine used to treat Type II Diabetes. It contains Dapagliflozin (sodium-glucose cotransporter-2 inhibitors) and Linagliptin (dipeptidyl peptidase-4 inhibitor). It reduces the sugar production by liver cells and delays sugar absorption from the intestines. Thus, It helps control blood sugar levels. Ondero-D 10 Tablet may cause side effects such as diarrhoea, headache, dizziness, hypoglycaemia, nausea, and vomiting.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

DAPAGLIFLOZIN-10MG+LINAGLIPTIN-5MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Ondero-D 10 Tablet

Ondero-D 10 Tablet is a prescription medication used to manage blood sugar levels in adults with type 2 diabetes mellitus. It helps control high blood sugar when used alongside a proper diet and exercise plan, reducing the risk of serious diabetes-related complications. This daily tablet contains two blood-sugar-lowering medicines that work in harmony to help you reach your long-term health goals.

For the best results, you should take Ondero-D 10 Tablet consistently at the same time every day, either with or without food. Staying regular with your medication helps maintain steady, predictable blood sugar levels throughout the day and night. Combining this daily treatment with a balanced, low-glycaemic diet and regular physical activity will significantly enhance your results.

While taking Ondero-D 10 Tablet , some people may experience mild side effects such as an increased need to urinate, mild nausea, or a stuffy nose. However, you must contact your doctor immediately if you face serious symptoms like severe abdominal pain, persistent vomiting, extreme dizziness, or signs of a severe urinary tract infection.

Before starting this medicine, talk to your doctor if you have a history of kidney disease, liver damage, pancreas problems, or frequent urinary tract infections. Do not take this medicine if you have type 1 diabetes, diabetic ketoacidosis, or severe kidney failure requiring dialysis.

This medication can interact with other blood pressure pills or other diabetes therapies, which can increase your risk of low blood sugar or dehydration. It is also important to avoid excessive alcohol consumption while taking this medication, as alcohol can increase the risk of a dangerous condition called ketoacidosis. If you are pregnant, planning to become pregnant, breastfeeding, or are over the age of 65, consult your doctor to ensure this treatment is safe for you.

Uses of Ondero-D 10 Tablet

Ondero-D 10 Tablet is used to treat Type 2 diabetes mellitus. The detailed uses of Ondero-D 10 Tablet are as follows:

  • Type 2 Diabetes Mellitus: Ondero-D 10 Tablet helps lower blood sugar levels in adults by helping the kidneys remove excess sugar through urine and improving the body's natural insulin response after meals.
  • Prevention of Diabetes Complications: By keeping blood sugar levels within a healthy target range, this medication helps reduce the long-term risk of kidney damage, nerve problems, blindness, and cardiovascular events.

Key Benefits

Ondero-D 10 Tablet helps manage type 2 diabetes by combining two blood sugar-lowering medicines in a single tablet. With regular use as prescribed, it helps provide effective glucose control, simplifies treatment, and reduces the risk of diabetes-related complications.

  • Provides Effective Blood Sugar Control: By combining two complementary medicines, this treatment helps control blood sugar levels throughout the day, including after meals, supporting better long-term glucose management and HbA1c control.
  • Simplifies Your Treatment Routine: The single-tablet formulation reduces the number of pills you need to take each day, making it easier to follow your treatment plan consistently.
  • Protects Against Long-Term Complications: Maintaining stable blood sugar levels helps protect the kidneys, eyes, nerves, heart, and blood vessels from the harmful effects of chronic high blood sugar, supporting better overall health and quality of life.
Side effects of Ondero-D 10 Tablet
Managing Medication-Triggered UTIs: A Comprehensive Approach:
  • Inform your doctor about the medication you're taking and the UTI symptoms you're experiencing.
  • Your doctor may adjust your medication regimen or consider alternative medications or dosages that may reduce the risk of UTIs.
  • Drink plenty of water (at least 8-10 glasses a day) to help flush out bacteria. Avoid sugary drinks and caffeine, which can exacerbate UTI symptoms.
  • Urinate when you feel the need rather than holding it in. This can help prevent bacterial growth and reduce the risk of UTIs.
  • Consider cranberry supplements: Cranberry supplements may help prevent UTIs by preventing bacterial adhesion.
  • Monitor UTI symptoms and report any changes to your doctor.
  • If antibiotics are prescribed, take them as directed and complete the full course.
  • Exercise for at least 30 minutes most days of the week.
  • Limit alcohol consumption.
  • Consider a low carbohydrate diet that limits grains, starchy vegetables and fruit. Include foods rich in protein and fat.
  • Avoid excess sugar, fatty foods and carbohydrates.
  • Aim for weight loss as it helps to improve cardiovascular health and minimize the risk of complications related to obesity.
  • Eat fiber-rich foods, fruits, and vegetables, and track your food intake to monitor calorie consumption.
  • Limit takeout and restaurant meals, and weigh yourself weekly to stay motivated.
  • Build balanced meals, allow yourself to enjoy treats in moderation, and prioritize sleep and stress management through exercise and relaxation techniques.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Directions for Use

  • Take Ondero-D 10 Tablet with or without food or as advised by a doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow the medicine as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Ondero-D 10 Tablet Works

Ondero-D 10 Tablet contains two active ingredients that work in completely different ways to manage your blood sugar levels. Together, they provide a dual-action approach to diabetes care. The first active ingredient, dapagliflozin, works directly on your kidneys. It blocks the proteins that normally reabsorb sugar back into your bloodstream. By doing this, it allows your kidneys to filter out excess sugar and flush it safely out of your body through your urine. The second active ingredient, linagliptin, works by helping your pancreas. It prevents the breakdown of natural hormones in your body that signal the pancreas to release more insulin when you eat. At the same time, it tells your liver to stop producing unnecessary sugar. Together, these dual actions ensure your blood sugar stays within a healthy, stable range.
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Alcohol

Unsafe

Avoid consumption of alcohol during treatment with Ondero-D 10 Tablet as it may cause serious side effects.

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Pregnancy

Consult your doctor

If you are pregnant or planning pregnancy, inform your doctor before starting treatment with Ondero-D 10 Tablet . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Limited data is available on the effect of Ondero-D 10 Tablet on breastfeeding. Hence, if you are a nursing mother, inform your doctor before taking Ondero-D 10 Tablet . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Caution

Ondero-D 10 Tablet may cause dizziness in some patients. Hence, drive or operate vehicles only if you are alert.

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Liver

Consult your doctor

If you have a pre-existing or a history of liver disease, inform your doctor before taking Ondero-D 10 Tablet . Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Consult your doctor

If you have a pre-existing or a history of kidney disease, inform your doctor before taking Ondero-D 10 Tablet . Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Ondero-D 10 Tablet is not recommended for use in children below 12 years of age as the safety and efficacy are not established.

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Heart

Safe if prescribed

Ondero-D 10 Tablet is generally safe for heart patients. However, it is important to consult your doctor if you have any concerns or underlying conditions.

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Geriatrics

Safe if prescribed

Ondero-D 10 Tablet is generally considered safe for use in geriatric patients; however, significant precautions should be taken due to age-related sensitivities.

What if I have taken an overdose of Ondero-D 10 Tablet

If you take more than your prescribed dose, seek emergency medical care immediately. Symptoms of an overdose may include severe dizziness, nausea, or a sudden, severe drop in blood sugar.

Diet & Lifestyle Advise

  • Monitor your carbohydrate intake: Focus on complex carbohydrates like whole grains, vegetables, and legumes, which raise blood sugar gradually, rather than refined sugars and sodas.
  • Stay consistently hydrated: Because one of the active ingredients works by removing sugar through your urine, you will lose more fluids than usual. Drink plenty of water throughout the day to prevent dehydration.
  • Establish a regular exercise routine: Aim for at least 150 minutes of moderate-intensity aerobic exercise, like brisk walking, per week to help your muscles use insulin more effectively.
  • Practice good foot care: People with diabetes are more prone to foot issues. Check your feet daily for cuts, sores, or redness, and keep them clean and dry.

Health Queries

Why is my wife's after-meal blood sugar level not decreasing after taking Ondero 5 mg, when she has had a hepatitis A liver infection for 15 days and her blood sugar has risen from 200 to 350, even though her liver test (bilirubin) levels have improved?

Y. Lakshmi Thulasi

Y. Lakshmi Thulasi

Pharm-D (Post baccalaureate)

When the body fights an infection like hepatitis A, it undergoes physical stress. This stress releases hormones that naturally raise blood sugar levels and make medications like Ondero (linagliptin) less effective, even as her liver begins to recover. Since her blood sugar has reached 350 mg/dL, it is very important to contact her doctor promptly. They may need to temporarily adjust her treatment, perhaps adding insulin, to safely bring her levels down while her body fully heals. Please keep her well-hydrated in the meantime.
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Have a query?

How Soon It Starts Working

  • The time required for Ondero-D 10 Tablet to start to work: Ondero-D 10 Tablet ideally shows its action within a few hours after administration.
  • The time for which the effects of Ondero-D 10 Tablet last: The duration of action for Ondero-D 10 Tablet is unknown.

What if you forget to take Ondero-D 10 Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take two doses at the same time to make up for a forgotten one.

Storage

• Store Ondero-D 10 Tablet tablets at room temperature, ideally between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Check your blood sugar levels regularly as directed by your doctor, especially during periods of stress, illness, or changes in your physical activity.
  • Stay alert for signs of low blood sugar (hypoglycemia), such as shakiness, sweating, fast heartbeat, and confusion, and always keep a fast-acting sugar source (like glucose tablets or fruit juice) nearby.
  • Pay close attention to your body during times of illness, fever, or poor eating; consult your doctor immediately if you feel extremely weak, nauseous, or have deep, rapid breathing, as these can be early signs of ketoacidosis.
  • If you are scheduled for any surgery or medical procedures that require fasting, talk to your doctor beforehand, as you may need to temporarily pause taking Ondero-D 10 Tablet .

Drug-Drug Interactions

verifiedApollotooltip
  • Insulin and Sulfonylureas: Combining Ondero-D 10 Tablet with these medications can significantly increase your risk of low blood sugar. Your doctor may need to adjust your doses.
  • Diuretics (Water pills): Taking this medication with diuretics can increase the risk of dehydration and dangerously low blood pressure.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Avoid heavy drinking or alcohol binges while taking this medication, as it significantly raises the risk of diabetic ketoacidosis and can cause unpredictable changes in blood sugar.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIDIABETICS]

FAQs

Ondero-D 10 Tablet belongs to the group of anti-diabetic medicines used to treat type-2 diabetes mellitus.
Ondero-D 10 Tablet is a combination medicine containing Linagliptin that enhances glucose-mediated insulin secretion, thereby reducing fasting and post-prandial blood sugar concentrations. Dapagliflozin helps remove excess sugar from the body via urine. Metformin helps reduce sugar production by cells in the liver and delays sugar absorption from the intestines.
Hypoglycemia/low blood sugar levels could be the side effect of Ondero-D 10 Tablet . Hypoglycemia generally occurs when Ondero-D 10 Tablet is taken along with other antidiabetic medicines, without food or with alcohol. Consume sugary food such as candy or fruit juice if you experience hypoglycemic symptoms such as dizziness, cold sweats, anxiety, or tremors. Regularly monitor blood glucose levels while taking Ondero-D 10 Tablet .
Low-fibre diets, high-fat diets, sugary diets, obesity, smoking, stress, lack of exercise, age, genetic factors, and certain medical conditions are the common causes of diabetes.
This medication relies on your kidneys to work safely and effectively. If you have mild to moderate kidney issues, your doctor will determine if this medication is safe for you. However, you should not take Ondero-D 10 Tablet if you have severe kidney failure or are on dialysis. Talk to your doctor.
While Ondero-D 10 Tablet is not prescribed specifically for weight loss, one of its active ingredients helps remove excess sugar through your urine, which can result in mild weight loss for some patients. However, weight changes vary from person to person. Talk to your doctor.
Using this medication during pregnancy is generally not recommended, especially during the second and third trimesters, as it may affect the developing baby. If you are pregnant or planning to become pregnant, your doctor will suggest alternative therapies. Talk to your doctor.
It is best to avoid or strictly limit alcohol while taking this medicine. Alcohol can increase your risk of developing low blood sugar or a serious, life-threatening condition called diabetic ketoacidosis. Talk to your doctor.
Yes. This medication works best when combined with a healthy, low-sugar diet and regular physical exercise. Medication is designed to support, not replace, these vital lifestyle habits. Talk to your doctor.
Because this medication helps your body remove excess sugar through your urine, the higher sugar content in your urinary tract can increase the risk of genital yeast infections in both men and women. Maintaining good hygiene can help reduce this risk. Talk to your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. U.S. Food and Drug Administration (FDA). 202293S020Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  2. National Center for Biotechnology Information (NCBI). Pmc8952231 Scientific Research Publication. Bethesda, MD: NLM; 2025. [Accessed on 02 Jun. 2026]Check here
  3. Linagliptin [Product Information]. 2020. [Accessed on 27 Sep. 2023]Check here
  4. Trajenta 5 mg film-coated tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2021 [Accessed on 4 March 2022]Check here
  5. Trajenta 5 mg film-coated tablets - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2021 [Accessed on 4 March 2022]Check here
  6. Forxiga 10 mg film-coated tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2022 [Accessed on 17 May 2022]Check here
  7. Forxiga 10 mg film-coated tablets - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2022 [Accessed on 17 May 2022]Check here

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3Rd Floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country Of Origin: India
Other Info - OND0188
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