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  3. Onimar 400 Tablet

Onimar 400 Tablet, Pack of 10 TabletS
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Onimar 400 Tablet is used for the management of asthma and chronic obstructive pulmonary disease (COPD). It contains Theophylline, which works by relaxing the airway in the lungs and making it easier to breathe. In some cases, you may experience side effects such as nausea, vomiting, restlessness, tremors, headache, muscle cramps, and increased heart rate. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

THEOPHYLLINE-400MG

Manufacturer/Marketer :

Emcee Pharmaceuticals (P) Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Onimar 400 Tablet

Onimar 400 Tablet is a respiratory medicine which belongs to the class of 'Xanthine' primarily used for the management of asthma and chronic obstructive pulmonary disease (COPD). Asthma is a breathing problem in which airways narrow, swell and may produce extra mucus, which may lead to breathing difficulty and trigger cough, a whistling sound (wheezing) when you breathe out and shortness of breath. COPD is a group of progressive lung diseases, most commonly emphysema (shortness of breath) and chronic bronchitis (inflammation and irritation of bronchial tubes). Initially, it may be mild, but in severe cases, it can lead to total blockage of airways and damage to the lungs.

Onimar 400 Tablet contains Theophylline, which helps in the treatment of asthma and chronic obstructive pulmonary disease (COPD). Theophylline works by relaxing the airway in the lungs and making it easier to breathe. In addition to this, theophylline also helps in treating the symptoms hence making it easier to treat. It is generally a long-term treatment.

You should take Onimar 400 Tablet without food, mostly on an empty stomach. It should be swallowed whole with a glass of water. Do not chew, bite, or break it. Your doctor will advise you on how often you take your tablets based on your medical condition. In some cases, you may experience nausea, vomiting, restlessness, tremors, headache, muscle cramps, and increased heart rate. Most of these side effects of Onimar 400 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Let your doctor know about this, as it may cause withdrawal symptoms. Do not take this medicine if you have any lung disease, muscle weakness (myasthenia gravis), sleeping disorder, difficulty in sleeping (sleep apnoea), severe liver disease, or problem with alcohol or other prescription recreational drugs. Onimar 400 Tablet is a habit-forming drug, and hence, there is a risk of dependence on this medicine. So, before stopping this medicine, contact a doctor as it may cause withdrawal symptoms like anxiety, increased heart rate, tremors, or general unwell feeling.

Uses of Onimar 400 Tablet

Onimar 400 Tablet is used in the treatment of Asthma, Chronic obstructive pulmonary disease (COPD). The detailed uses of Onimar 400 Tablet are as follows:<br/>• Asthma Management: Onimar 400 Tablet is used to treat asthma symptoms, such as wheezing, coughing, and shortness of breath.<br/>• Chronic Obstructive Pulmonary Disease (COPD): Onimar 400 Tablet helps to manage symptoms of COPD, including bronchitis and emphysema.<br/>• Improving Breathing: Onimar 400 Tablet relaxes and opens air passages in the lungs, making it easier to breathe by reducing inflammation and increasing airflow, thereby providing relief from respiratory symptoms.<br/>

Directions for Use

• Onimar 400 Tablet should be taken on an empty stomach, at least 1 hour before or 2 hours after a meal.• Avoid taking it with foods high in caffeine, such as cocoa, tea, coffee, and chocolate, as these foods may increase the risk of side effects.• It is usually taken 1-4 times a day, or as prescribed by your doctor, depending on the severity of your medical condition.• Swallow Onimar 400 Tablet as a whole with a glass of water.• Do not crush or chew this medication.

Medicinal Benefits

Onimar 400 Tablet contains Theophylline, which helps in the treatment of asthma and chronic obstructive pulmonary disease (COPD). Theophylline works by relaxing the airway in the lungs and making it easier to breathe. In addition to this, theophylline also helps in treating the symptoms hence making it easier to treat. It is generally a long-term treatment.

How Onimar 400 Tablet Works

Onimar 400 Tablet contains Theophylline, which helps in the treatment of asthma and chronic obstructive pulmonary disease (COPD). Theophylline works by relaxing the airway in the lungs and making it easier to breathe. In addition to this, theophylline also helps in treating the symptoms hence making it easier to treat. It is generally a long-term treatment.
Side effects of Onimar 400 Tablet
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Maintain consistent habits, sleep patterns and food times to help maintain stability and reduce confusion.
  • Mindfulness techniques such as deep breathing or meditation help you stay focused and in the now.
  • Participate in cognitive therapy to enhance your ability to remember, focus and solve problems.
  • As directed by your physician, take your medications to help control underlying disorders like depression, anxiety or cognitive impairment.
Here are the steps to manage medication-triggered tremors or involuntary shaking:
  • Notify your doctor immediately if you experience tremors or involuntary shaking after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen or recommend alternative techniques like relaxation, meditation, or journaling to alleviate tremor symptoms.
  • Your doctor may direct you to practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling.
  • Regular physical activity, such as walking or jogging, can help reduce anxiety and alleviate tremor symptoms.
  • Your doctor may recommend lifestyle changes, such as avoiding caffeine, getting enough sleep, and staying hydrated, to help manage tremors.
  • Maintain regular follow-up appointments with your doctor to monitor tremor symptoms and adjust treatment plans as needed.

What if I have taken an overdose of Onimar 400 Tablet

Do not take more than the prescribed dose of Onimar 400 Tablet as it may cause overdose. The symptoms of overdose include slow heart rate, seizures (fits), fainting or weak pulse. Seizures caused due to overdose of Theophylline may cause permanent brain damage or it can be fatal. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take this medicine if you have any lung disease, muscle weakness (myasthenia gravis), sleeping disorder or difficulty in sleeping (sleep apnoea), severe liver disease, or problem with alcohol or other prescription recreational drugs. Onimar 400 Tablet is a habit-forming drug, so there is a risk of dependence on this medicine. So, before stopping this medicine, contact a doctor as it may cause withdrawal symptoms like anxiety, increased heart rate, tremors, or general unwell feeling.

Drug-Drug Interactions

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TheophyllineRiociguat
Critical
TheophyllineLabetalol
Severe

Drug-Drug Interactions

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TheophyllineRiociguat
Critical
How does the drug interact with Onimar 400 Tablet:
Co-administration of Onimar 400 Tablet with Riociguat can increase the risk of low blood pressure.

How to manage the interaction:
Taking Onimar 400 Tablet with Riociguat is not recommended but can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, lightheadedness, fainting, flushing (a sudden reddening of the face), headache, and nasal congestion (stuffy nose). Do not discontinue any medications without consulting a doctor.
TheophyllineLabetalol
Severe
How does the drug interact with Onimar 400 Tablet:
Taking Labetalol with Onimar 400 Tablet may reduce the effectiveness of Labetalol and increase Onimar 400 Tablet's effects.

How to manage the interaction:
Although taking Labetalol and Onimar 400 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience sleeplessness, shaking, irregular heartbeats, or trouble breathing, consult a doctor. Do not discontinue any medications without a doctor's advice.
TheophyllinePindolol
Severe
How does the drug interact with Onimar 400 Tablet:
Taking pindolol with Onimar 400 Tablet, could make pindolol less effective and increase the effects of Onimar 400 Tablet.

How to manage the interaction:
Although taking pinolol and Onimar 400 Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as nausea, vomiting, insomnia, tremors, restlessness, uneven heartbeats, or difficulty breathing, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
TheophyllineBisoprolol
Severe
How does the drug interact with Onimar 400 Tablet:
Co-administration of Bisoprolol with Onimar 400 Tablet may cause Bisoprolol to be less effective and increase the effects of Onimar 400 Tablet.

How to manage the interaction:
Although there may be an interaction, Bisoprolol can be taken with Onimar 400 Tablet if prescribed by the doctor. Consult the prescriber if you experience nausea, vomiting, insomnia, shaking hands and legs, restlessness, uneven heartbeats, or difficulty breathing. Do not discontinue the medication without consulting a doctor.
TheophyllineNebivolol
Severe
How does the drug interact with Onimar 400 Tablet:
Combined use of Nebivolol with Onimar 400 Tablet may increase the effect of Onimar 400 Tablet.

How to manage the interaction:
Although there is a possible interaction between Onimar 400 Tablet and Nebivolol, you can take these medicines together if prescribed by your doctor. However, if you experience nausea, vomiting, insomnia, tremors, restlessness, irregular heartbeats, contact a doctor. Do not discontinue any medications without a doctor's advice.
TheophyllineBupropion
Severe
How does the drug interact with Onimar 400 Tablet:
Co-administration of Onimar 400 Tablet with bupropion can increase the risk of seizures (fits).

How to manage the interaction:
Co-administration of bupropion along with Onimar 400 Tablet can lead to an interaction, it can be taken if recommended by a doctor. In case you experience any symptoms like Temporary confusion, A state of staring, Uncontrollable jerking movements of the arms and legs, Consciousness or awareness loss, Changes in cognition or emotion, consult a doctor. Do not discontinue any medications without consulting a doctor.
TheophyllineDeferasirox
Severe
How does the drug interact with Onimar 400 Tablet:
Taking deferasirox with Onimar 400 Tablet may significantly increase the blood levels of Onimar 400 Tablet.

How to manage the interaction:
Although taking deferasirox and Onimar 400 Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as nausea, vomiting, diarrhea, loss of hunger, headache, shaking, confusion, restlessness, sleeplesness, fits, heart palpitations, and/or irregular heartbeat. Do not discontinue any medications without consulting a doctor.
TheophyllineMetoprolol Tartrate
Severe
How does the drug interact with Onimar 400 Tablet:
Taking Metoprolol Tartrate with Onimar 400 Tablet could make Metoprolol Tartrate less effective and increase the side effects of Onimar 400 Tablet

How to manage the interaction:
Although taking metoprolol tartrate and Onimar 400 Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as nausea, vomiting, insomnia, tremors, restlessness, uneven heartbeats, or difficulty breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TheophyllineNebivolol
Severe
How does the drug interact with Onimar 400 Tablet:
Coadministration of Nebivolol with Onimar 400 Tablet may reduce the effect of Nebivolol.

How to manage the interaction:
Taking Nebivolol with Onimar 400 Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as nausea, vomiting, insomnia, tremors, restlessness, uneven heartbeats, or difficulty breathing, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
TheophyllinePropranolol
Severe
How does the drug interact with Onimar 400 Tablet:
Using propranolol together with Onimar 400 Tablet makes the propranolol less effective in controlling blood pressure, and it also increases the effects of Onimar 400 Tablet

How to manage the interaction:
Although taking Propranolol together with Onimar 400 Tablet can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor if you experience nausea, vomiting, sleeplessness, tremors, restlessness, irregular heartbeats, or difficulty breathing. Do not stop using any medication without consulting a doctor.

Drug-Food Interactions

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THEOPHYLLINE-400MGCaffeine containing foods/drinks
Moderate

Drug-Food Interactions

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THEOPHYLLINE-400MGCaffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Caffeine consumption can modify Onimar 400 Tablet blood levels. Caffeine should be avoided in excess while using Onimar 400 Tablet. Consult a doctor if you suffer any symptoms such as headaches, sleeplessness, or increases in blood pressure or heart rate. Do not discontinue any medications without consulting a doctor.

Diet & Lifestyle Advise

  • Eat a healthy diet specially green leafy vegetables and strictly do not consume alcohol, caffeine (coffee, tea and cola drinks and chocolate). Here Caffeine is a stimulant and can decrease Onimar 400 Tablet’s calming effects and alcohol can enhance Onimar 400 Tablet's effects.
  • Smoking should be avoided while taking Onimar 400 Tablet as it can alter the blood levels of theophylline, which may affect the dosing.
  • It is very important to maintain hygiene like washing hands after coming from outside as people with asthma/COPD are at a greater risk to infections.
  • Stay active and do regular exercise to improve quality of life and increase tolerance to shortness of breath.
  • Talk with family member if you feel low or are stressed as it helps to improve symptoms of COPD and keep it under control.
  • Shortness of breath can be eased by doing pursed lip breathing exercise. In this, just relax your neck and shoulder muscles, breathe in with your nose for two seconds and breathe out through pursed lips for four seconds. Such exercises will help you to improve your breath.

Habit Forming

No

Therapeutic Class

ANTIHYPONATREMIC

Onimar 400 Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Alcohol can alter the way Onimar 400 Tablet works. Please consult your doctor if you intend to drink alcohol whilst taking Onimar 400 Tablet.

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Pregnancy

Safe if prescribed

If you are breastfeeding do not take Onimar 400 Tablet until you have talked to your doctor.

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Breast Feeding

Safe if prescribed

If you are pregnant do not take Onimar 400 Tablet until you have talked to your doctor.

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Driving

Unsafe

Onimar 400 Tablet usually causes dizziness, drowsiness and visual disturbances which may affect their ability to drive or operate machinery. So, do not drive or operate heavy machinery if you feel sleepy or dizzy after taking Onimar 400 Tablet. Tell your doctor if you get these types of side effects.

bannner image

Liver

Caution

Onimar 400 Tablet to be taken with caution, especially if you have a history of liver disease. The dose may have to be adjusted by your doctor.

bannner image

Kidney

Safe if prescribed

Onimar 400 Tablet does not have any reported interaction; hence, in case you experience any difficulty discuss with your doctor.

bannner image

Children

Caution

Children under six years of age should not take Onimar 400 Tablet.

Have a query?

FAQs

Onimar 400 Tablet is used to manage asthma and chronic obstructive pulmonary disease (COPD).

Onimar 400 Tablet contains Theophylline, which relaxes the lungs&amp;#039; airways and makes breathing easier.

If you remember within 4 hours of the time Onimar 400 Tablet was due, take Onimar 400 Tablet straight away. Take your next dose at your normal time. Do not take a double dose to make up for a forgotten does of Onimar 400 Tablet.

Yes, Onimar 400 Tablet can lead to withdrawl symptoms. So, it should not be stopped abruptly. Consult your doctor and your dose might be lowered if required.

No, dose of Onimar 400 Tablet should not be increased without consulting your doctor as it may increase risk of hypokalemia (high blood potassium level) which may lead to side effects of Onimar 400 Tablet and also effect its efficacy.

No, you should not take Onimar 400 Tablet if you have ulcers as it may worsen your ulcers and lead to bleeding and inflammation. So, please consult your doctor before starting Onimar 400 Tablet as dose adjustment may be required.

Onimar 400 Tablet is contraindicated in patients who are allergic to any of its ingredients. It is advised to avoid taking Onimar 400 Tablet and beta-blockers like propranolol together at once.

No, Onimar 400 Tablet should not be taken with any medication, if you are taking it for seizures it might worsen your condition and lead to symptoms like confusion, trouble talking, tremors or twitching, loss of muscle tone or tense muscles.

You will probably be prescribed Onimar 400 Tablet for a long time. Do not stop taking them unless your doctor tells you to, even if you feel better.

Onimar 400 Tablet may cause side effects such as vomiting, diarrhoea, dizziness and indigestion. If these side effects persist or worsen, please consult your doctor.

Take Onimar 400 Tablet as advised by your doctor. Swallow it as a whole with a glass of water. Do not break, crush or chew it.

Onimar 400 Tablet starts working quickly and you may see an improvement in symptoms within about 30 minutes of taking it. However, it may take a little longer about 4 to 8 hours to show full effect. If there is no considerable improvement in your symptoms, consult your doctor.

While taking Onimar 400 Tablet, you should avoid foods high in caffeine such as cocoa, tea, coffee, and chocolate as these foods increase Onimar 400 Tablet side effects. Also, you should avoid alcohol and tobacco. If you have any concerns regarding food restriction, please discuss with your doctor.

Country of origin

India

Manufacturer/Marketer address

DB-107, Ground Floor, Sector-I, Salt Lake City, Kolkata- 700064
Other Info - ONI0031

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:33 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.1021.pdf
  2. https://www.drugs.com/mtm/theophylline.html
  3. https://www.asthma.org.uk/advice/inhalers-medicines-treatments/add-on-treatments/theophylline/
  4. https://www.healthline.com/health/copd/lifestyle-changes-help-manage

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