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compositionComposition:METOPROLOL SUCCINATE-47.5MG
prescription
Prescription Medicine
info
Opramet 50 Tablet PR

Opramet 50 Tablet PR belongs to the class of antihypertensive medicines used in the treatment of high blood pressure. This medicine also helps reduce the chances of heart problems such as heart attack and stroke. This medicine suppresses the contraction of blood vessels and promotes smooth blood flow. It also alters the response to nerve impulses in the heart, thereby making the heart pump blood more easily. Common side effects include dizziness, tiredness, diarrhoea, stomach pain, nausea, and headache.

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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

METOPROLOL SUCCINATE-47.5MG

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Opramet 50 Tablet PR

Opramet 50 Tablet PR is used in the treatment of high blood pressure (hypertension), heart-related chest pain (angina), and irregular heart rhythm (arrhythmia). Hypertension is a lifelong or chronic condition in which the force exerted by the blood against the artery walls becomes so high that it leads to heart disease.

Opramet 50 Tablet PR contains Metoprolol Succinate, which helps in slowing down the heart rate, making it easier for the heart to pump blood throughout the body.

Not everyone who is taking Opramet 50 Tablet PR will get these side effects. In some cases, Opramet 50 Tablet PR may cause certain common side effects like dizziness, tiredness, diarrhoea, stomach pain, nausea, and headache. Most of these side effects do not require medical attention and resolve gradually over time. However, if the side effects are persistent, reach out to your doctor.

You can take Opramet 50 Tablet PR with food or without food. It should be swallowed as a whole with a glass of water. Do not chew, bite, crush, or break it. Your doctor will advise you on how often you should take your tablets based on your medical condition. It is always important to complete your treatment course for better results.

Inform your doctor if you are allergic to Opramet 50 Tablet PR. Also, let your doctor know if you have low blood pressure, asthma, an overactive thyroid, metabolic acidosis, or severe blood circulation problems. Consult your doctor before taking Opramet 50 Tablet PR if you are pregnant or breastfeeding. Opramet 50 Tablet PR is not recommended for use in children. Opramet 50 Tablet PR may cause dizziness, so drive with caution.

Uses of Opramet 50 Tablet PR

Opramet 50 Tablet PR is used in the treatment of High blood pressure (hypertension), prevention of heart-related chest pain (angina), heart rhythm disorder (arrhythmia), and heart attack (myocardial infarction). The detailed uses of Opramet 50 Tablet PR are as follows:

  • Treatment of Hypertension: Opramet 50 Tablet PR controls high blood pressure by reducing the heart rate and the force of contraction, thereby lowering blood pressure.
  • Prevention of Heart-related Chest Pain: Opramet 50 Tablet PR prevents chest pain (angina) by reducing the workload on the heart and improving blood flow to the heart muscle.
  • Control of Abnormal Heart Rhythms: Opramet 50 Tablet PR helps manage irregular heartbeats (arrhythmias) by slowing the heart rate and stabilizing the heart's rhythm, reducing symptoms and improving heart function.
  • Management of Heart Attack: Opramet 50 Tablet PR is used to manage heart attack (myocardial infarction) by reducing the workload on the heart and preventing further damage.

Key Benefits

  • Opramet 50 Tablet PR helps in slowing down the heart rate, making it easier for the heart to pump blood throughout the body.
  • This medicine lowers the blood pressure and helps in reducing the risk of having a stroke, heart attack, or other heart or kidney problems in the future.
  • Opramet 50 Tablet PR may also help in relieving symptoms of migraine-related headache and tremors (fits).

Directions for Use

  • Opramet 50 Tablet PR can be taken with or without food, or as advised by your doctor.
  • Generally, it is recommended to be taken once daily. Follow your doctor's instructions regarding dosage and timing for optimal results.
  • Swallow Opramet 50 Tablet PR as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Opramet 50 Tablet PR Works

Opramet 50 Tablet PR contains Metoprolol succinate, which helps in slowing down the heart rate, making it easier for the heart to pump blood throughout the body. This lowers blood pressure and helps in reducing the risk of having a stroke, heart attack, or other heart or kidney problems in the future.
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Alcohol

Unsafe

Alcohol might increase the blood pressure-lowering effect of Opramet 50 Tablet PR. It might also cause increased dizziness. Therefore, avoid alcohol consumption while taking Opramet 50 Tablet PR.

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Pregnancy

Unsafe

Opramet 50 Tablet PR belongs to pregnancy category C. Opramet 50 Tablet PR is not recommended for use during pregnancy. If you are pregnant, think you are pregnant or planning for pregnancy, consult your doctor.

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Breast Feeding

Caution

Opramet 50 Tablet PR may pass into breastmilk. Consult a doctor before taking Opramet 50 Tablet PR if you are breastfeeding.

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Driving

Caution

Opramet 50 Tablet PR may cause dizziness and tiredness. Therefore, drive or operate machinery only if you are alert.

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Liver

Caution

Dose adjustment may be needed. Consult your doctor before taking Opramet 50 Tablet PR if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Consult your doctor before taking Opramet 50 Tablet PR if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Opramet 50 Tablet PR is not recommended in children as the safety and efficacy have not been established.

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Heart

Caution

Opramet 50 Tablet PR should be taken with caution in patients with heart problems. Therefore, please talk to your doctor before using Opramet 50 Tablet PR.

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Geriatrics

Caution

Opramet 50 Tablet PR should be given at a lower dose for elderly patients to minimize risks, as advised by a healthcare professional.

What if I have taken an overdose of Opramet 50 Tablet PR

Do not take more than the prescribed dose. Overdose of Opramet 50 Tablet PR may cause nausea, vomiting, decreased consciousness or loss of consciousness (coma), irregular, fast, or slow heartbeat, chest pain, dizziness, fatigue or weakness and fainting. Seek immediate medical help if you suspect that you might have taken an overdose of Opramet 50 Tablet PR.

Diet & Lifestyle Advise

  • Maintain a healthy body weight, ideally with a BMI between 18.5 and 24.9, as excess weight increases the risk of high blood pressure and heart disease.
  • Engage in regular physical activity, aiming for at least 150 minutes of moderate-intensity exercise per week (e.g., brisk walking, cycling, swimming) to help lower blood pressure by about 5–8 mmHg.
  • Limit sodium intake to ≤2300 mg per day, with an ideal goal of 1500 mg daily for adults with high blood pressure or heart problems.
  • If you drink alcohol, limit intake to up to 1 drink per day for women and up to 2 drinks per day for men, as excessive drinking can raise blood pressure.
  • Quit smoking, as it significantly increases the risk of heart attack, stroke, and complications from high blood pressure.
  • Manage stress through relaxation techniques, deep breathing, mindfulness, adequate sleep, and spending time with loved ones to help maintain stable blood pressure levels.
  • Monitor blood pressure regularly at home and keep a record. Contact your doctor promptly if you notice frequent or large fluctuations.
  • Eat a heart-healthy diet, rich in fruits, vegetables, whole grains, lean protein, and omega-3 fatty acids (from fish, flaxseeds, or walnuts) to support cardiovascular health.
  • Use healthy cooking oils such as olive, canola, or soybean oil, and limit saturated fats to help manage blood pressure and improve heart health.
  • Follow your doctor’s advice strictly regarding medications, diet, and lifestyle adjustments to reduce the risk of severe heart complications.

Have a query?

How Soon It Starts Working

The time required for Opramet 50 Tablet PR to start to work: Opramet 50 Tablet PR ideally shows its action within 1 hour after administration. The time for which the effects of Opramet 50 Tablet PR last: The effect of Opramet 50 Tablet PR lasts for 12 hours.

What if you forget to take Opramet 50 Tablet PR

Take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for the missed dose.

Storage

• Store in a cool and dry place away from sunlight. • Keep Opramet 50 Tablet PR out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Do not take Opramet 50 Tablet PR if you are allergic to any component present in Opramet 50 Tablet PR or any other beta-blockers.
  • Avoid taking Opramet 50 Tablet PR if you have/had heart conduction, rhythm problems, uncontrolled/severe heart failure, blocked blood vessels, blood circulation problems, untreated pheochromocytoma, metabolic acidosis, low blood pressure, or Prinzmetal angina.
  • Inform your doctor if you have asthma, COPD, diabetes, blood vessel disorder, slow heart rate, pheochromocytoma, myasthenia gravis, dry eye problems, kidney or liver impairment; if you are taking anti-depressants, other blood pressure-lowering medicines, or anti-arrhythmic agents.
  • Consult your doctor before taking Opramet 50 Tablet PR if you are pregnant or breastfeeding.
  • Opramet 50 Tablet PR is not recommended for children as safety and efficacy have not been established.
  • Opramet 50 Tablet PR may cause dizziness, so drive with caution.
  • Don't stop taking Opramet 50 Tablet PR without consulting your doctor. Suddenly stopping the use of Opramet 50 Tablet PR may cause changes in your heart rhythm and blood pressure, cause chest pain, or a heart attack. Your doctor will gradually lower your dose to help prevent these symptoms.

verifiedApollotooltip

Drug-Drug Interaction: Opramet 50 Tablet PR may interact with antacid (cimetidine), blood pressure-lowering agents (hydralazine, clonidine, prazosin), anti-arrhythmic (amiodarone, propafenone), anaesthetics (cyclopropane), anxiolytics (temazepam, nitrazepam, diazepam), NSAID's (indomethacin, celecoxib), antibiotic (rifampicin), anti-fungal (terbinafine), corticosteroids (hydrocortisone, prednisolone), a local anaesthetic (lidocaine), anti-depressants, barbiturates, phenothiazines, and other beta-blockers.

Drug-Food Interaction: Alcohol might increase the blood pressure-lowering effect of Opramet 50 Tablet PR. It might also cause increased dizziness. Therefore, avoid alcohol consumption while taking Opramet 50 Tablet PR.

Drug-Disease Interaction: Opramet 50 Tablet PR may have interaction with disease conditions such as heart conduction problems, rhythm problems, uncontrolled/severe heart failure, blocked blood vessels, blood circulation problems, untreated pheochromocytoma (tumour in the adrenal gland), metabolic acidosis (excess acid in the body), low blood pressure, and Prinzmetal angina.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

FAQs

Opramet 50 Tablet PR is used to treat high blood pressure (hypertension), prevention of heart-related chest pain (angina), heart rhythm disorder (arrhythmia), and heart attack (myocardial infarction).
Opramet 50 Tablet PR helps in slowing down the heart rate, making it easier for the heart to pump blood throughout the body. Thereby, lowers blood pressure.
High blood pressure increases the workload on the arteries and heart. If untreated, it could damage the blood vessels of the heart, brain, kidney and might result in stroke, heart failure or kidney failure. Hypertension increases the risk of heart attacks. Therefore, anti-hypertensives such as Opramet 50 Tablet PR are used to lower the blood pressure to normal; this reduces the risk of developing these disorders.
Do not stop taking Opramet 50 Tablet PR without consulting your doctor, as it may lead to a rise in blood pressure. To treat your condition effectually, continue taking Opramet 50 Tablet PR for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Opramet 50 Tablet PR.
Consult your doctor before taking Opramet 50 Tablet PR if you have hyperthyroidism (overactive thyroid) as it might mask the symptoms or make it difficult to recognise the signs of thyrotoxicosis (excess thyroid hormone in the body).
Consult your doctor before taking Opramet 50 Tablet PR with anti-diabetic medicines as it might mask the signs of low blood sugar. Regular monitoring of blood glucose levels while taking Opramet 50 Tablet PR is advised.
Your doctor may probably ask you to stop taking Opramet 50 Tablet PR 24hours prior to the surgery, as it might lower blood pressure when combined with general anaesthesia. If you are due to have any surgery or are receiving an anaesthetic, inform the doctor that you are taking Opramet 50 Tablet PR.
Taking Opramet 50 Tablet PR along with multivitamin/multimineral supplements may decrease the effect of Opramet 50 Tablet PR. Therefore, maintain a gap of at least 2hours between both. However, you are advised to take Opramet 50 Tablet PR with other medicines only after consulting your doctor.
Yes, Opramet 50 Tablet PR is a selective beta-blocker, that acts on the heart muscles.
No, do not stop taking Opramet 50 Tablet PR if your blood pressure level comes in control as discontinuing suddenly may worsen the condition. Therefore, continue taking Opramet 50 Tablet PR for long as it is advised by your doctor.
No, Opramet 50 Tablet PR is not a blood thinner. Opramet 50 Tablet PR relaxes the blood vessels, and slows down the heart rate. Thereby, it reduces the workload on the heart and makes it easier to pump blood effectively.
The time taken by Opramet 50 Tablet PR to start working varies from person to person. Usually, it starts working within 15 minutes. However, it may take up to 2 hours to start working in some people. The maximum or full effect is usually achieved within 1 week as it starts acting slowly. In case you do not feel any difference while taking Opramet 50 Tablet PR, do not worry. It exerts its beneficial effects when taken for a long time.
The side effects of Opramet 50 Tablet PR include stomach pain, nausea, diarrhoea, dizziness, tiredness or headache. If these side effects persist or worsen, please consult your doctor.
Opramet 50 Tablet PR is generally safe if used as prescribed by the doctor. If this medication is stopped suddenly, it may cause harmful effects such as a sudden increase in the heart rate and affect its activity, which can be dangerous for heart failure patients and in some cases even result in a heart attack. Therefore, take Opramet 50 Tablet PR for the prescribed duration and do not stop taking it suddenly.
Opramet 50 Tablet PR belongs to the class of medicines called beta-blockers. Though their effect on sleep differs from person to person, it has been found that these medications are known to change the sleep pattern and disturb sleep in some patients. On the other hand, it has also been observed to promote better sleep in patients with increased anxiety and heart rate by calming down the nerves and heart. If you have any sleep disturbances, please consult your doctor.
No, you are recommended to avoid alcohol consumption after taking Opramet 50 Tablet PR as alcohol might increase the blood pressure-lowering effect of Opramet 50 Tablet PR and might cause increased dizziness.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Drugs.com Clinical Review Team. Metoprolol Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  2. National Health Service (NHS). Metoprolol - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026] Check here
  3. Electronic Medicines Compendium (EMC). Pil.5816 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  4. U.S. Food and Drug Administration (FDA). 019962S032Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026] Check here
  5. Metoprolol succinate [Prescribing Information]. 2010. [Accessed on 30 Apr. 2025] Check here
  6. Morris J, Dunham A Metoprolol. [Updated 2022 Oct. 2]. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Check here
  7. METOPROLOL SUCCINATE capsule, extended release [Internet]. Dailymed.nlm.nih.gov. 2025 [Accessed on 21st Nov 2025]Check here

Country of origin

India
Other Info - OP55813
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