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compositionComposition:CEFUROXIME-250MG
prescription
Prescription Medicine
info
Oratil 250 Tablet 10's
Oratil 250 Tablet 10's
Oratil 250 Tablet 10's
Oratil 250 Tablet 10's
Oratil 250 Tablet 10's

ORATIL 250MG TABLET is used to treat bacterial infections. It contains Cefuroxime, which works by killing infection-causing bacteria. It may cause common side effects like headache, dizziness, stomach upset, and unpleasant taste in the mouth. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

CEFUROXIME-250MG

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About ORATIL 250MG TABLET

ORATIL 250MG TABLET belongs to the class of antibiotics known as cephalosporin, indicated for treating a wide range of bacterial infections. It helps in the treatment of urinary tract infections, respiratory tract infections, uncomplicated gonorrhoea (sexually transmitted infection), and Lyme disease.

ORATIL 250MG TABLET contains Cefuroxime, a broad-spectrum antibiotic which works by blocking the activity of the enzyme that makes peptidoglycan (a vital component of the bacterial cell wall). As a result, the bacterial cell cannot grow and multiply and finally gets killed.

ORATIL 250MG TABLET may cause side effects like headache, dizziness, stomach upset, overgrowth of candida (fungal skin infection), and unpleasant taste in the mouth. These side effects usually resolve after some time. However, if these side effects persist, consult your doctor.

Do not take ORATIL 250MG TABLET if you are allergic to any of its components. Consult your doctor if you are pregnant or breastfeeding. Keep your doctor informed about your health conditions and medications to prevent any potential interactions.

Uses of ORATIL 250MG TABLET

ORATIL 250MG TABLET is used in the treatment of Bacterial infections. The detailed uses of ORATIL 250MG TABLET are as follows:

  • Bacterial Infections: ORATIL 250MG TABLET is commonly used to treat various bacterial infections, including respiratory tract infections, urinary tract infections, ear Infections, and skin infections.
  • Treatment of Bronchitis: ORATIL 250MG TABLET can help treat bronchitis, an infection of the airway tubes leading to the lungs, by targeting the underlying bacterial cause.
  • Treatment of Gonorrhea: ORATIL 250MG TABLET treats gonorrhea, eliminating the bacteria and alleviating symptoms.
  • Treatment of Lyme Disease: ORATIL 250MG TABLET can be used to treat Lyme disease, a bacterial infection caused by tick bites, helping to eliminate the bacteria and manage symptoms.
  • Treatment of Throat or Tonsil Infections: ORATIL 250MG TABLET can be used to treat bacterial infections of the throat or tonsils, helping to relieve symptoms.
  • Treatment of Sinusitis: ORATIL 250MG TABLET can effectively treat sinus infections caused by susceptible bacteria, alleviating symptoms like nasal congestion and facial pain.
  • Pneumonia Treatment: ORATIL 250MG TABLET is sometimes prescribed to treat pneumonia, especially community-acquired infections, helping patients recover faster.

Key Benefits

  • ORATIL 250MG TABLET is a broad-spectrum antibiotic used to treat a wide variety of bacterial infections caused by both gram-positive and gram-negative bacteria.
  • It is highly effective in the treatment of respiratory tract infections, ear infections, skin and soft tissue infections, genitourinary tract infections, and bone infections.
  • In addition to treating active infections, ORATIL 250MG TABLET is also prescribed to prevent the spread of infections following a surgical procedure.
  • It is also used in the early treatment of Lyme disease, caused by the bacterium Borrelia burgdorferi, in adults and children over 12 years of age.
  • ORATIL 250MG TABLET demonstrates strong antibacterial activity against a range of bacteria, including Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes, Haemophilus influenzae, Haemophilus parainfluenzae, Klebsiella pneumoniae, Moraxella catarrhalis, and Neisseria gonorrhoeae.
Side effects of Oratil 250 Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Inflammation of Vagina needs immediate attention and cannot be ignored.
  • Get a physical examination and prevent wearing clothes that can hold heat and moisture.
  • Avoid using vaginal sprays or perfumed soaps that increase itching and irritation.
  • Follow your doctor's instructions, and rest well with proper medication.
  • Take a balanced diet and get regular screenings to reduce inflammation.

Directions for Use

  • ORATIL 250MG TABLET can be taken with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow ORATIL 250MG TABLET as a whole with a glass of water.
  • Do not crush, break, or chew it.

How ORATIL 250MG TABLET Works

ORATIL 250MG TABLET is a broad-spectrum antibiotic that kills a wide range of bacteria (bactericidal). It kills the bacteria by binding to the outer layer and blocking the activity of the enzyme that makes peptidoglycan (a vital component of the bacterial cell wall). As a result, the bacterial cell cannot grow and multiply and finally gets killed.
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Alcohol

Unsafe

You are recommended not to consume alcohol along with ORATIL 250MG TABLET.

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Pregnancy

Safe if prescribed

ORATIL 250MG TABLET is a pregnancy category B drug. So, ORATIL 250MG TABLET can be safely taken by pregnant women if prescribed by the doctor.

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Breast Feeding

Caution

ORATIL 250MG TABLET is excreted in human milk; caution should be exercised. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Driving

Caution

No studies on the effects on the ability to drive and use machines have been performed. However, as this medicine may cause dizziness, patients should be warned to be cautious when driving or operating machinery.

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Liver

Caution

Consult your doctor; there is no substantial research yet on the use of ORATIL 250MG TABLET in patients with liver problems.

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Kidney

Caution

Consult your doctor, as there is no substantial research yet on the use of ORATIL 250MG TABLET in people with kidney problems.

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Children

Safe if prescribed

ORATIL 250MG TABLET can be given safely to children provided the dose has been prescribed by a child specialist. However, there is no clinical evidence of using ORATIL 250MG TABLET in children under the age of 3 months.

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Heart

Consult your doctor

Please consult your doctor before using ORATIL 250MG TABLET if you have pre-existing heart problems. Your doctor will prescribe ORATIL 250MG TABLET if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Please consult a doctor before administering ORATIL 250MG TABLET to geriatric patients. Your doctor will prescribe ORATIL 250MG TABLET if the benefits outweigh the risks.

What if I have taken an overdose of ORATIL 250MG TABLET

Do not take more than the prescribed dose of ORATIL 250MG TABLET as it may cause an overdose. The symptoms of overdose include seizures (fits). If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • It would be best to take probiotics after taking the full course of ORATIL 250MG TABLET to restore some of the healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria, which helps stimulate their growth. Thus, fibre foods may help restore healthy gut bacteria after taking a course of antibiotics. Whole grains like whole-grain bread and brown rice should be included in your diet.
  • Avoid taking too much calcium-enriched foods and drinks, as it might affect the working of ORATIL 250MG TABLET.
  • Avoid intake of alcoholic beverages with ORATIL 250MG TABLET as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the ORATIL 250MG TABLET in fighting off infections.

Have a query?

How Soon It Starts Working

The time required for ORATIL 250MG TABLET to start to work: ORATIL 250MG TABLET ideally shows its action within 2 to 3 hours after administration. The time for which the effects of ORATIL 250MG TABLET last: The effect of ORATIL 250MG TABLET lasts for 8 hours.

What if you forget to take ORATIL 250MG TABLET

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and take the next dose at the scheduled time. Do not take a double dose.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Do not take ORATIL 250MG TABLET if you are allergic to any of its components.
  • ORATIL 250MG TABLET may cause Clostridioides difficile-associated diarrhoea (CDAD). If you experience severe, persistent diarrhoea, or if you find blood or mucus in your stools, consult your doctor immediately.
  • Consult your doctor if you are pregnant or breastfeeding.
  • Let your doctor know if you have pre-existing medical conditions or are taking any other medicines, including supplements and herbal products.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions: You should avoid taking ORATIL 250MG TABLET with oral birth control pills, medicines that reduce gastric acidity (like antacids, omeprazole), immunosuppressing drugs (mycophenolate or mycophenolic acid), medicines used for reducing uric acid (probenecid), and some urine glucose tests. Besides this, it also interacts with typhoid and BCG vaccines.

Drug-Food Interactions: Grapefruit juice and dietary supplements containing minerals like calcium may dampen the effect of antibiotics.

Drug-Disease Interactions: Inform your doctor if you have colitis, kidney disease, dialysis, liver disease, epilepsy (fits) or diarrhoea.

CefuroximeBCG vaccine
Severe
CefuroximeDalteparin
Severe

Drug-Drug Interactions

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CefuroximeBCG vaccine
Severe
How does the drug interact with Oratil 250 Tablet:
Co-administration of Oratil 250 Tablet may reduce the anti-tumor activity of BCG in the bladder.

How to manage the interaction:
Talk to your doctor before receiving BCG if you are currently being treated with Oratil 250 Tablet. To ensure adequate response to your treatment, you should not receive BCG until after you complete your antibiotic therapy. Do not discontinue the medication without consulting a doctor.
CefuroximeDalteparin
Severe
How does the drug interact with Oratil 250 Tablet:
Co-administration of Dalteparin and Oratil 250 Tablet can increase the blood levels and effects of Dlateparin.

How to manage the interaction:
Taking Oratil 250 Tablet with Dalteparin together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
CefuroximeLepirudin
Severe
How does the drug interact with Oratil 250 Tablet:
The therapeutic efficacy of Lepirudin can be decreased when used in combination with Oratil 250 Tablet.

How to manage the interaction:
Although taking Oratil 250 Tablet and Lepirudin together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

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Therapeutic Class

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FAQs

ORATIL 250MG TABLET is used to treat a wide range of bacterial infections. It helps in the treatment of urinary tract infections (UTI), mild to moderate lower respiratory tract infections (bronchitis), severe lower respiratory tract infections (pneumonia), pyelonephritis (kidney inflammation due to the bacterial infection), uncomplicated gonorrhoea (sexually transmitted infection), and Lyme disease (caused due to biting of infected black-legged tick insect).
ORATIL 250MG TABLET is a broad-spectrum antibiotic that kills a wide range of bacteria (bactericidal). It kills the bacterial cell by binding to the outer layer of the bacteria and blocking the activity of the enzyme that makes peptidoglycan (a vital component of the bacterial cell wall). As a result, the bacterial cell cannot grow and multiply and finally gets killed.
No, it is a prescribed drug, given by a physician for preventing specific medical conditions. Taking it on your own can cause unwanted side effects.
You should avoid taking ORATIL 250MG TABLET with oral birth control pills, medicines that reduce gastric acidity (like antacids, omeprazole), immunosuppressing drugs (mycophenolate or mycophenolic), medicines used for reducing uric acid (probenecid), and some urinary glucose tests. Besides this, it also interacts with typhoid and BCG vaccines.
Depending upon the severity of your medical condition, your doctor may prescribe it to you daily for a specific duration. The usual dose of ORATIL 250MG TABLET is 5-10 days, but depending on your current infection state, your doctor may extend your dose intake for more days.
Try to stay well hydrated by drinking at least six glasses of water or other fluids per day. Keep your underwear clean and try to use cotton underwear to avoid the spread of infection. Always keep your bladder empty as much as possible by peeing regularly. Your doctor may prescribe cranberry juice with antibiotics to treat a urinary tract infection.
After taking an antibiotic, you may need to wait for up to three hours before eating or drinking any dairy products, including milk, butter, yoghurt, and cheese. Grapefruit juice and dietary supplements containing minerals like calcium may also work to dampen the effect of antibiotics.
If you have taken an accidental overdose of ORATIL 250MG TABLET, you may have diarrhoea, nausea or vomiting. In rare cases, it can also cause convulsions or seizures (fits). Try to reach out to the doctor in this case.
No. ORATIL 250MG TABLET treats only bacterial infection. Cough, flu or cold are usually caused by viruses. So, you should consult a doctor for these conditions.
Yes. ORATIL 250MG TABLET may interact with birth control pills and lower their efficiency. So, you should tell your doctor if you are using any birth control pills.
No. You should complete the full course of ORATIL 250MG TABLET as your doctor prescribes. You must take ORATIL 250MG TABLET at the right dose, times, and for the right number of days.
ORATIL 250MG TABLET might be a safer alternative if you are allergic to amoxicillin. However, please consult the doctor before starting ORATIL 250MG TABLET.
ORATIL 250MG TABLET helps treat respiratory tract infections, ear infections, skin infections, genitourinary infections, and bone infections.
ORATIL 250MG TABLET may cause dizziness in some cases. Therefore, drive or operate machinery only if you are alert.
Do not discontinue ORATIL 250MG TABLET without consulting the doctor. To treat your infection effectively, continue taking ORATIL 250MG TABLET for the prescribed duration even though you feel better.
If you miss a dose of ORATIL 250MG TABLET take it as soon as you remember, However, if it is almost time for the scheduled dose, skip the missed dose and take the next dose at the scheduled time.
ORATIL 250MG TABLET may interact with other medications. Consult the doctor if you are taking oral birth control pills, antacids, immuno-suppressing drugs, or medicines used for reducing uric acid.
Avoid alcohol consumption as it might lower the effectiveness of ORATIL 250MG TABLET.
ORATIL 250MG TABLET can be taken by pregnant or breastfeeding women if prescribed by the doctor. Please consult the doctor if you are pregnant, think you are pregnant, planning for pregnancy or breastfeeding.
Side effects of ORATIL 250MG TABLET include headache, dizziness, stomach upset, overgrowth of candida (fungal skin infection), and an unpleasant taste in the mouth. Consult the doctor if the side effects persist or worsen.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. U.S. Food and Drug Administration (FDA). 050605S048,050672S034Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026] Check here
  2. Electronic Medicines Compendium (EMC). Product Summary of Product Characteristics (SmPC). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  3. Electronic Medicines Compendium (EMC). Pil.3810 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  4. Drugs.com Clinical Review Team. Cefuroxime Patient Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  5. Cefuroxime [EMC SmpC]. 2025. [Accessed on 29 Oct. 2025] Check here
  6. Cefuroxime Cefuroxime. 2025. [Accessed on Feb 2 2026] Check here
  7. Zinnat Tablets 125mg - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2025 [Accessed on 27 Oct 2025]Check here

Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Other Info - ORA0062

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