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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Orsimet-PG2 Tablet 10's is used to treat type 2 diabetes. It works by reducing sugar production in the liver, delaying sugar absorption from the intestines, and removing sugar from the blood. In some cases, this medicine may cause side effects such as stomach pain, nausea, diarrhoea, vomiting, headache, metallic taste, or low blood sugar. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Manufacturer/Marketer :

Orchis Pharmaceuticals

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

About Orsimet-PG2 Tablet 10's

Orsimet-PG2 Tablet 10's belongs to a class of medicines called anti-diabetic drugs used in the treatment of type 2 diabetes, especially in patients whose blood sugar levels are not controlled by diet and exercise alone. Type 2 diabetes is a chronic (long-lasting) condition that affects the way our body processes glucose.

Orsimet-PG2 Tablet 10's contains Glimepiride, Metformin, and Pioglitazone. Glimepiride lowers blood sugar by causing the pancreas to produce insulin. Metformin reduces the production of sugar in the liver and delays sugar absorption from the intestines. Pioglitazone increases the body's sensitivity to insulin. Thereby, Orsimet-PG2 Tablet 10's helps to control blood sugar levels.

In some cases, you may experience stomach pain, nausea, diarrhoea, vomiting, headache, a metallic taste, or low blood sugar. Most of these side effects of Orsimet-PG2 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Orsimet-PG2 Tablet 10's or any other medicines, please tell your doctor. Orsimet-PG2 Tablet 10's is not recommended for children. Consult your doctor if you are breastfeeding, pregnant or planning for pregnancy. Avoid alcohol consumption with Orsimet-PG2 Tablet 10's as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body).

Uses of Orsimet-PG2 Tablet 10's

Orsimet-PG2 Tablet 10's is used in the treatment of type 2 diabetes mellitus. The detailed uses of Orsimet-PG2 Tablet 10's are as follows:

  • Manages Type 2 Diabetes Mellitus: Orsimet-PG2 Tablet 10's to treat type 2 diabetes, especially in patients whose blood sugar levels are not controlled by diet and exercise alone.
  • Reduces Risk of Diabetes-Related Complications: By effectively controlling blood sugar levels, Orsimet-PG2 Tablet 10's helps reduce the risk of long-term complications such as neuropathy and cardiovascular disease.

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Directions for Use

  • Orsimet-PG2 Tablet 10's can be taken with food to avoid stomach upset or as advised by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Orsimet-PG2 Tablet 10's as a whole with a glass of water.
  • Do not chew, crush or break it.

Key Benefits

  • Orsimet-PG2 Tablet 10's is effective in controlling blood sugar levels in people with Type 2 Diabetes.
  • It combines three complementary antidiabetic agents to provide comprehensive glycemic control when diet, exercise, or monotherapy is insufficient.
  • Glimepiride works by stimulating beta cells in the pancreas that produce insulin. Thus, insulin helps to remove sugar from the blood.
  • Metformin works by reducing the sugar production by cells in the liver and delaying sugar absorption from the intestines. Also, it increases the sensitivity of muscle cells to insulin, which enables these cells to remove sugar more effectively from the blood.
  • Pioglitazone works by increasing the sensitivity of liver, muscle and fat cells to insulin and enabling them to remove glucose from the blood more effectively.
  • This medicine ensures long-lasting glycaemic control, reducing the frequency of dosage. It also prevents unnecessary sugar spikes.
  • Orsimet-PG2 Tablet 10's manages blood glucose levels, thereby lowering the risk of complications such as nerve problems, kidney problems, eye problems, and cardiovascular disease.

How Orsimet-PG2 Tablet 10's Works

Orsimet-PG2 Tablet 10's contains Glimepiride, Metformin, and Pioglitazone. Glimepiride lowers blood sugar by causing the pancreas to produce insulin. Metformin reduces the production of sugar in the liver and delays sugar absorption from the intestines. Pioglitazone increases the body's sensitivity to insulin. Thereby, Orsimet-PG2 Tablet 10's helps to control blood sugar levels.

Storage

Store in a cool and dry place away from sunlight
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the steps to manage the medication-triggered Sinusitis (Sinus infection or Inflammation Of Sinuses):
  • Consult your doctor if you experience symptoms of sinusitis, such as nasal congestion, facial pain, or headaches, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your sinusitis symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • If your doctor advises, you can use nasal decongestants or saline nasal sprays to help relieve nasal congestion and sinus pressure.
  • To help your body recover, get plenty of rest, stay hydrated, and engage in stress-reducing activities. If your symptoms persist or worsen, consult your doctor for further guidance.
Here are the step-by-step strategies to manage the side effects of " Muscle Pain" caused by medication usage:
  • Report to Your Doctor: Inform your doctor about the muscle pain, as they may need to adjust your medication.
  • Stretch Regularly: Gentle stretching can help relieve muscle pain and stiffness.
  • Stay Hydrated: Adequate water intake supports muscle health by removing harmful substances and maintaining proper muscle function.
  • Warm or Cold Compresses: Apply cold or warm compresses to the affected area to reduce pain and inflammation.
  • Rest and Relaxation: Adequate rest helps alleviate muscle strain, while relaxation techniques like deep breathing and meditation can soothe muscle tightness, calm the mind, and promote relief from discomfort.
  • Gentle Exercise: Participate in low-impact activities, such as yoga or short walks, to improve flexibility, reduce muscle tension, and alleviate discomfort.
  • Consult a physician: If your symptoms don't improve or get worse, go to the doctor for help and guidance.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.

What if I have taken an overdose of Orsimet-PG2 Tablet 10's

Take Orsimet-PG2 Tablet 10's only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include loss of consciousness, lactic acidosis (buildup of lactic acid in the blood), and pancreatitis (inflammation of the pancreas). If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • If you are allergic to Orsimet-PG2 Tablet 10's or any other medicines, please tell your doctor.
  • Orsimet-PG2 Tablet 10's is not recommended for children.
  • Avoid breastfeeding while taking Orsimet-PG2 Tablet 10's as it may be excreted in human milk.
  • If you are pregnant or planning for pregnancy, please inform your doctor before taking Orsimet-PG2 Tablet 10's as it may harm the unborn baby.
  • Orsimet-PG2 Tablet 10's should be used with caution in elderly patients.
  • Avoid alcohol consumption with Orsimet-PG2 Tablet 10's as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body).
  • Drive only if you are alert after taking Orsimet-PG2 Tablet 10's.
  • Let your doctor know if you are taking any other medicines, including supplements and herbal products.

Drug-Drug Interactions

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MetforminIopanoic acid
Critical
MetforminIohexol
Critical

Drug-Drug Interactions

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MetforminIopanoic acid
Critical
How does the drug interact with Orsimet-PG2 Tablet:
Co-administration of Iopanoic acid with Orsimet-PG2 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Orsimet-PG2 Tablet with Iopanoic acid is not recommended, please consult your doctor before taking it.
MetforminIohexol
Critical
How does the drug interact with Orsimet-PG2 Tablet:
Co-administration of Iohexol with Orsimet-PG2 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Orsimet-PG2 Tablet with Iohexol is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIopromide
Critical
How does the drug interact with Orsimet-PG2 Tablet:
Co-administration of Iopromide with Orsimet-PG2 Tablet can increase the risk of lactic acidosis.

How to manage the interaction:
Taking Iopromide with Orsimet-PG2 Tablet is not recommended, please consult a doctor before taking it. Do not discontinue the medication without consulting a doctor.
MetforminIodixanol
Critical
How does the drug interact with Orsimet-PG2 Tablet:
Co-administration of Iodixanol with Orsimet-PG2 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Orsimet-PG2 Tablet with Iodixanol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIopamidol
Critical
How does the drug interact with Orsimet-PG2 Tablet:
Co-administration of Iopamidol with Orsimet-PG2 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Orsimet-PG2 Tablet with Iopamidol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIoglycamic acid
Critical
How does the drug interact with Orsimet-PG2 Tablet:
Co-administration of Ioglycamic acid with Orsimet-PG2 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Orsimet-PG2 Tablet with Ioglycamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIocarmic acid
Critical
How does the drug interact with Orsimet-PG2 Tablet:
Co-administration of Orsimet-PG2 Tablet and Iocarmic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Orsimet-PG2 Tablet with Iocarmic acid is generally avoided as it can result in an interaction. please consult your doctor before taking it.
MetforminIomeprol
Critical
How does the drug interact with Orsimet-PG2 Tablet:
Co-administration of Iomeprol with Orsimet-PG2 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Orsimet-PG2 Tablet with Iomeprol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIotroxic acid
Critical
How does the drug interact with Orsimet-PG2 Tablet:
Co-administration of Iotroxic acid with Orsimet-PG2 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Orsimet-PG2 Tablet with Iotroxic acid is not recommended, please consult your doctor before taking it.
MetforminIoglicic acid
Critical
How does the drug interact with Orsimet-PG2 Tablet:
Co-administration of Ioglicic acid with Orsimet-PG2 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Orsimet-PG2 Tablet with Ioglicic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do regular exercise such as cycling, walking, jogging, dancing or swimming for a minimum of 30 minutes per day. Invest at least 150 minutes of your week in exercise.
  • Maintain a healthy body weight, as obesity is also related to the onset of diabetes.
  • Maintain a low-fat and low-sugar diet. Replace carbohydrate-containing foods with whole grains, fruits and vegetables, as carbohydrates turn to sugars, leading to high blood sugar.
  • Avoid consumption of alcohol and quit smoking.

Habit Forming

No

Therapeutic Class

[ANTIDIABETICS]

All Substitutes & Brand Comparisons

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Alcohol

Safe if prescribed

You are recommended to avoid consumption of alcohol with Orsimet-PG2 Tablet 10's as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body).

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Pregnancy

Consult your doctor

Orsimet-PG2 Tablet 10's is not recommended for pregnant women as it may harm an unborn baby. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Consult your doctor

Avoid breastfeeding while taking Orsimet-PG2 Tablet 10's as it may be excreted in breastmilk and cause adverse effects in the baby. Therefore, please consult a doctor before using Orsimet-PG2 Tablet 10's if you are breastfeeding.

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Driving

Safe if prescribed

Orsimet-PG2 Tablet 10's may decrease alertness in some people. Therefore, drive only if you are alert after taking Orsimet-PG2 Tablet 10's.

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Liver

Consult your doctor

Take Orsimet-PG2 Tablet 10's with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Consult your doctor

Take Orsimet-PG2 Tablet 10's with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Safe if prescribed

Orsimet-PG2 Tablet 10's is not recommended for children as the safety and effectiveness were not established.

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Heart

Orsimet-PG2 Tablet 10's should be used with caution in patients with heart problems. Inform your doctor about any heart-related conditions before taking Orsimet-PG2 Tablet 10's.

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Geriatrics

Consult your doctor

Orsimet-PG2 Tablet 10's should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using Orsimet-PG2 Tablet 10's.

FAQs

Orsimet-PG2 Tablet 10's is used in the treatment of type 2 diabetes, especially in patients whose blood sugar levels are not controlled by diet and exercise alone.

Orsimet-PG2 Tablet 10's contains Glimepiride, Metformin, and Pioglitazone. Glimepiride lowers blood sugar by causing the pancreas to produce insulin. Metformin reduces the production of sugar in the liver and delays sugar absorption from the intestines. Pioglitazone increases the body's sensitivity to insulin. Thereby, Orsimet-PG2 Tablet 10's helps to control blood sugar levels.

Orsimet-PG2 Tablet 10's may increase the risk of low blood sugar levels, especially with alcohol intake, when you exercise more than usual, delay or miss snacks or meals. However, if you experience any signs of low blood pressure such as dizziness, nausea, light-headedness, dehydration or fainting, please consult a doctor.

You are not recommended to take Orsimet-PG2 Tablet 10's with pregabalin as it may cause weight gain and fluid retention that could lead to heart failure. However, please consult a doctor before using Orsimet-PG2 Tablet 10's with other medicines.

In type 1 diabetes, the body does not produce insulin as the islet cells (insulin-producing cells) in the pancreas are completely destroyed. In type 2 diabetes, though islet cells are working, the body does not respond to insulin as the body becomes resistant to it.

You are not recommended to stop taking Orsimet-PG2 Tablet 10's on your own, as discontinuing Orsimet-PG2 Tablet 10's suddenly may cause recurring symptoms or worsen the condition. However, if you experience any difficulty while taking Orsimet-PG2 Tablet 10's, please consult your doctor so that alternative medicine may be prescribed.

Yes, Orsimet-PG2 Tablet 10's may cause stomach upset as a side effect. Drink water/fluids in small, frequent amounts and chew the food properly while eating.

You are recommended to avoid consumption of alcohol with Orsimet-PG2 Tablet 10's as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body).

Inform the doctor if you are taking any other medicines, have any other medical conditions, and if you are pregnant or breastfeeding.

Yes, Orsimet-PG2 Tablet 10's may lead to vitamin B12 deficiency, particularly on long-term use. Consult the doctor if you experience symptoms of vitamin b12 deficiency such as headache, loss of appetite, fatigue, mental impairment, pins and needle sensation, and pale skin.

Store Orsimet-PG2 Tablet 10's at room temperature, in a dry place. Keep out of sight and reach of children.

Orsimet-PG2 Tablet 10's may cause side effects like stomach pain, nausea, diarrhoea, vomiting, headache, metallic taste, or low blood sugar. If the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Orchid Towers' #313, Valluvar Kottam High Road Nungambakkam Chennai - 600 034 Tamil Nadu, India
Other Info - ORS0097

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