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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Oxifyline PR 400 Tablet 15's is used to treat pain in the legs due to insufficient blood flow (intermittent claudication). It also reduces cramping, numbness, or weakness in the legs on walking in such patients. It works by decreasing the viscosity (thickness) of blood, allowing it to pass more easily through the blood vessels, especially in the small blood vessels of the hands and feet. It can also increase the distance you can walk without pain since it improves your legs blood circulation. It is recommended in patients whose pain has not improved even after lifestyle changes like quitting smoking and doing regular exercise. In some cases, it may cause side effects such as nausea, vomiting, diarrhoea, headache, lightheadedness, sleep problems, intrahepatic cholestasis (removal of bile from the liver is blocked), abdomen pain, constipation, and urine discolouration.
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Manufacturer/Marketer :

Steris Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Oxifyline PR 400 Tablet 15's

Oxifyline PR 400 Tablet 15's belongs to a class of medicines called Hemorrheologic agents (affects blood viscosity), primarily used to treat pain in the legs due to insufficient blood flow (intermittent claudication). It also reduces cramping, numbness, or weakness in the legs on walking in such patients. Intermittent claudication is a peripheral vascular disease in which you have cramp-like pain in your legs when you walk and is caused by an insufficient blood supply in your legs.

Oxifyline PR 400 Tablet 15's works by decreasing the viscosity (thickness) of blood, allowing it to pass more easily through the blood vessels, especially in the small blood vessels of the hands and feet. It can also increase the distance you can walk without pain since it improves your legs' blood circulation. It is recommended in patients whose pain has not improved even after lifestyle changes like quitting smoking and doing regular exercise.

Oxifyline PR 400 Tablet 15's should be taken regularly in dose and duration as advised by the doctor. Your doctor will advise you on the exact dosage and how often you have to take Oxifyline PR 400 Tablet 15's based on your medical condition. You may experience nausea, vomiting, diarrhoea, headache, lightheadedness, sleep problems, intrahepatic cholestasis (removal of bile from the liver is blocked), abdomen pain, constipation, and urine discolouration in some cases. Most of these side effects of Oxifyline PR 400 Tablet 15's do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Oxifyline PR 400 Tablet 15's should not be stopped abruptly without consulting the doctor as it may lead to unpleasant side effects. Inform your doctor before starting Oxifyline PR 400 Tablet 15's if you have any kidney or liver disease or plan to become pregnant, or are breastfeeding. Also, lifestyle changes should be continued with Oxifyline PR 400 Tablet 15's for best results. Do not take Oxifyline PR 400 Tablet 15's if you ever had bleeding in your brain or the retina of your eyes, heart failure, chest pain, heart disease, and blood pressure.

Uses of Oxifyline PR 400 Tablet 15's

Oxifyline PR 400 Tablet 15's is used in the treatment of intermittent claudication. The detailed uses of Oxifyline PR 400 Tablet 15's are as follows:

  • Treats Intermittent Claudication: Oxifyline PR 400 Tablet 15's improves blood flow by decreasing blood viscosity (thickness), thereby helping to relieve leg pain and cramps experienced during walking or at rest due to poor blood circulation (intermittent claudication).
  • Manages Peripheral Vascular Disease (PVD): Oxifyline PR 400 Tablet 15's enhances blood circulation in the arms and legs, thereby reducing symptoms of PVD such as numbness, pain, and cramping.

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Directions for Use

  • Oxifyline PR 400 Tablet 15's can be taken with meals or as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Oxifyline PR 400 Tablet 15's as a whole with a glass of water.
  • Do not chew, crush, or break it.

Medicinal Benefits

Oxifyline PR 400 Tablet 15's contains 'Pentoxyfilline', which is a peripheral vasodilator that works by decreasing the viscosity (thickness) of blood, allowing it to pass more easily through the blood vessels, especially in the small blood vessels of the hands and feet. It can also increase the distance you can walk without pain since it improves your legs' blood circulation. It is recommended in patients whose pain has not improved even after lifestyle changes like quitting smoking and doing regular exercise.

How Oxifyline PR 400 Tablet 15's Works

Oxifyline PR 400 Tablet 15's works by decreasing the viscosity (thickness) of blood, allowing it to pass more easily through the blood vessels, especially in the small blood vessels of the hands and feet. It can also increase the distance you can walk without pain since it improves your legs' blood circulation.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Oxifyline PR 400 Tablet 15's

Do not take more than the prescribed dose of Oxifyline PR 400 Tablet 15's as it may cause overdose. The symptoms of overdose include fever, severe drowsiness, fainting, seizures (fits), or flushing (warmth, redness, or tingly feeling). If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Oxifyline PR 400 Tablet 15's if you are allergic to any of its components. Inform your doctor if you are pregnant or breastfeeding. Before taking Oxifyline PR 400 Tablet 15's, please tell your doctor if you are using any blood thinners, as it can increase the risk of severe bleeding. Oxifyline PR 400 Tablet 15's is not intended for prolonged use unless prescribed by a physician. Inform your doctor if have had any type of bleeding in your brain or the retina of your eyes, have low blood pressure (less than 90 mm of Hg), or have had a heart attack, kidney disease, or liver disease. Tell your doctor that you are using Oxifyline PR 400 Tablet 15's before undergoing any dental or other surgery. Your doctor might stop this medicine before the surgery. Oxifyline PR 400 Tablet 15's should not be stopped abruptly without consulting the doctor as it may lead to unpleasant side effects. Also, lifestyle changes should be continued with Oxifyline PR 400 Tablet 15's for best results and a speedy recovery.

Diet & Lifestyle Advise

  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.

  • Lsodium chloride (table salt) intake alt) in your daily diet.

  • Quitting smoking is the best strategy to lower the risk of heart disease.

  • Avoid chronic stress. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.

  • Try to include heart-healthy omega-3 fatty acid-containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

VASODILATORS

All Substitutes & Brand Comparisons

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Alcohol

Caution

Avoid consumption of alcohol with Oxifyline PR 400 Tablet 15's as it may increase adverse effects such as dizziness, fainting, light-headedness or headache.

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Pregnancy

Caution

Oxifyline PR 400 Tablet 15's is a Category C pregnancy drug and is given to pregnant women only if the doctor thinks the benefits outweigh the risks. Please consult a doctor if you are pregnant.

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Breast Feeding

Unsafe

Oxifyline PR 400 Tablet 15's is not recommended for breastfeeding mothers as it may harm the baby.

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Driving

Caution

Drive with caution, Oxifyline PR 400 Tablet 15's may cause blurry vision, and dizziness or weariness.

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Liver

Caution

Oxifyline PR 400 Tablet 15's to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Oxifyline PR 400 Tablet 15's to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Oxifyline PR 400 Tablet 15's is not recommended for children. The safety and effectiveness of Oxifyline PR 400 Tablet 15's have not been established in children.

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Heart

Consult your doctor

Please inform your doctor if you have any pre-existing heart problems

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Geriatrics

Safe if prescribed

Oxifyline PR 400 Tablet 15's can be given safely to the elderly if advised by the doctor.

FAQs

Oxifyline PR 400 Tablet 15's is used to treat pain in the legs due to insufficient blood flow (intermittent claudication). It also reduces cramping, numbness, or weakness in the legs when walking in such patients.

No, you should not stop taking Oxifyline PR 400 Tablet 15's even if you feel better as the pain might come back and become even worse.

No, it is a prescribed drug given by a physician to prevent specific medical conditions. Taking it on your own can cause unwanted side effects.

Oxifyline PR 400 Tablet 15's is not a blood thinner. Oxifyline PR 400 Tablet 15's contains 'Pentoxifylline' that belongs to a group of medicines called peripheral vasodilators, primarily used to treat pain in the legs due to insufficient blood flow (intermittent claudication).

If you forget to take Oxifyline PR 400 Tablet 15's at any time, take it as soon as you remember, then continue to take it at the usual times. Do not take a double dose to make up for a forgotten dose.

Country of origin

India

Manufacturer/Marketer address

A.O. : 328-A, Tanaji Chowk, New Mill Road, Kurla (West), Mumbai 400070.
Other Info - OXI0403

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